The SAM model demonstrates excellent generalization on common scenes, but requires strong prior knowledge for complex scenarios and performs poorly on low-contrast applications. It also struggles with professional data, particularly in medical and industrial settings.
A special issue of WORK Journal explores the importance of designing healthy workplaces that address musculoskeletal conditions, burnout, and chronic pain. The issue highlights the need for an interdisciplinary approach integrating medical, psychological, and occupational therapies to prevent work-related illness and injury.
The ZEN-MRI project, funded by the German Ministry of Education and Research, aims to achieve a congenial co-existence between human beings and robots in public areas. Researchers will investigate how to design robots that are perceived as unthreatening and sympathetic.
The study found that the percentage of hospitals offering at least one form of telemedicine service increased from 46% in 2017 to 72% in 2021. Despite rapid growth, persistent disparities in implementation across different hospital types and challenges in health information exchange remain.
A study by Michigan Medicine found that older women over 65 who require complex heart surgery are more likely to be treated at low-quality hospitals, where they also die in greater numbers. The sex disparity in mortality doubled from high-quality to low-quality hospitals.
A team of researchers led by Professor Peter Fineran from the University of Otago discovered a novel regulatory mechanism in a protein used by phages to deploy anti-CRISPR. This finding has significant implications for understanding gene regulation and developing new antimicrobial therapies.
Researchers from Leiden University discuss targeting ABC transporters in pancreatic ductal carcinoma (PDAC), a cancer with poor survival rates. The authors highlight the potential of inhibiting ABC transporters to overcome chemoresistance and suggest developing stratification protocols to identify patients most likely to benefit.
A study found that giving children digital devices to manage tantrums fails to teach them how to regulate their emotions, instead leading to severe problems. Parents' reliance on digital devices can exacerbate existing emotion regulation issues, emphasizing the need for alternative methods such as coaching and emotional recognition.
Researchers have developed a novel method to significantly enhance quantum technology performance by leveraging cross-correlation of two noise sources. This approach extends coherence time, improves control fidelity, and increases sensitivity for high-frequency sensing.
Researchers found Ptip to suppress SSC glycolysis by downregulating Pgk1, improving function despite deficiency. This establishes a new epigenetic framework for Ptip's role in SSC quiescence and potency.
Researchers developed a CRISPR/Cas9 genome editing approach to target and disrupt a specific mutation causing progressive hearing loss. The study found robust preservation of auditory function, with earlier intervention proving most optimal.
A Northwestern University study reveals the experimental evidence for how the surface of iridium oxide changes during water electrolysis, enabling the design of a novel catalyst with higher activity and longer stability. The new catalyst is three to four times more efficient than existing iridium-based catalysts.
A team of researchers from the University of Kansas has discovered a microscopic mechanism that explains why a new class of organic semiconductors outperforms others. This breakthrough could lead to more efficient solar cells and photocatalysts for producing solar fuels, revolutionizing the clean energy sector.
Research reveals that residents of America's wealthiest communities face higher economic losses from natural disasters and exposure to air pollution, despite having more assets. In contrast, low-income municipalities have higher suicide rates, homicide rates, and firearm fatalities, but lower access to health services.
Researchers uncover the importance of kainate receptors in enabling synaptic plasticity and transmission in the cerebellum. The study's findings have significant implications for understanding neurological disorders and developing new treatments.
A University of Michigan study suggests that up to 60% of near-Earth objects could be dark comets containing ice. Dark comets are a mysterious mix of asteroid and comet characteristics and may have delivered water to Earth through their sublimating ice, creating nongravitational accelerations.
A team of researchers has created a molecular atlas of the human brain's vasculature, revealing how endothelial cells regulate interactions between the bloodstream and surrounding tissues. The study provides insights into the growth patterns of blood vessels in early development, adulthood, and disease stages.
Researchers at HZB have developed a method to precisely monitor electrochemical reactions in solid-state batteries using photoelectron spectroscopy at BESSY II. The results show that decomposition products form at interfaces, hindering lithium ion transport and reducing battery capacity with each charge cycle.
A massive harmful algal bloom was detected in the Bering Strait region of western Alaska in 2022, posing an unprecedented risk to human and ecosystem health. The bloom, caused by the single-celled organism Alexandrium catenella, was tracked using new technology and communicated to remote coastal communities in real-time.
Researchers from Monell Chemical Senses Center discovered a population of neurons controlling food intake without inducing nausea in an animal model. The study found that targeting these neurons could lead to improved weight loss medications with fewer side effects.
Scientists have discovered that planted mangroves can store a significant amount of carbon, reaching levels comparable to those in intact stands after just 20 years. The study used logistic models compiled from over 700 planted mangrove stands worldwide and found that the trees' carbon stock reached 71-73% of that found in intact stands.
Researchers have successfully synchronized a 220-year-old map of Southern Germany from the Napoleonic era with modern databases, allowing for tracking of historical and environmental changes. The map was produced in haste during the wars, resulting in errors that were corrected through geospatial analysis.
A new coordinated care model, Trauma Medical Home, has been found to improve psychological recovery and quality of life for older adults with trauma-related injuries. The care model provides comprehensive support, including medication adherence and cognitive assessments, to help patients recover from physical or psychological injury.
A new potential therapy for depressed patients with bipolar disorder has emerged, significantly shortening treatment time from four to six weeks. Accelerated intermittent theta burst stimulation (aiTBS) reduced treatment to just five days, yielding substantial decreases in depressive symptoms.
A six-year longitudinal study found that loneliness has a significant impact on memory, even when social isolation is not present. The research suggests that community programs are needed for older adults who are both socially isolated and lonely, as they face the highest risk of memory impairment.
England's first patient safety commissioner Henrietta Hughes warns that the NHS's relentless focus on finance and productivity is failing to prioritize patient safety. Patients' concerns are often ignored, dismissed, or gaslighted, and it's not until a serious issue arises that action is taken.
A new graphene-based material, EGNITE, enhances the performance of neuroprostheses by improving electrode size and selectivity. In animal models, EGNITE showed improved muscle activation and biocompatibility, paving the way for potential clinical translation.
Scientists have discovered a new genus and species of dinosaur, Comptonatus chasei, which is the most complete dinosaur found in the UK in a century. The specimen, around 125 million years old, has a unique pubic hip bone and was named after Nick Chase, a fossil collector who found it.
Scientists have discovered a new hormone, CCN3, that helps maintain bone density and strength in breastfeeding women. In mice, CCN3 increased bone mass and strength, even when estrogen levels were low. The hormone also accelerated bone healing in fracture models, offering hope for treating osteoporosis and other bone conditions.
Researchers at the University of Utah and Max Planck Institute have discovered an intermediate-mass black hole in the Omega Centauri cluster, providing crucial evidence for a long-theorized class of black holes. The discovery offers insights into galaxy evolution and the formation history of globular clusters.
A novel technique called time-division MIMO beamformer enables millimeter-wave MIMO receivers without additional hardware, achieving -23.5 dB error vector magnitude and rapid Nyquist-rate beam switching times. This innovation paves the way for smaller and more efficient multi-beam MIMO systems.
Scientists developed customized AI tools, including ChatGPT, to provide accurate responses on digital pathology. The tools help pathologists without extensive coding experience analyze tissue samples, bridging the gap between pathology and digital pathology skills.
Researchers at Tsinghua University have developed a novel method for producing dimethoxymethane (DMM), a promising alternative to traditional fossil fuels. The team used phosphorus-modified nanocarbon catalysts, which demonstrated high methanol conversion rates and DMM selectivity.
Researchers have discovered an antibody fragment that can bind to abnormal light chains, stabilizing them and preventing their aggregation. This finding has the potential to provide a much-needed treatment for individuals with light chain amyloidosis, which currently has a poor prognosis.
A meta-analysis of North American correspondence studies found that perceived warmth and competence ratings predicted callback differences between identities. Applicants with lower callback rates were often rated as less warm and competent, highlighting the role of social perceptions in hiring bias.
The Xanthomonas cucurbitae pathogen that causes bacterial spot has remained genetically uniform across the Midwest, with most isolates sharing over 99% identical DNA sequences. This lack of diversification may hinder the pathogen's ability to evolve and could be leveraged for developing disease-resistant crops.
Researchers have made significant strides in multimodal sentiment recognition, leveraging self-supervised learning and large models to capture correlations between modalities and emotional information. The study emphasizes the importance of addressing data scarcity and exploring transfer learning methods to develop robust models.
A new study reveals that coca plants grown for cocaine production are difficult to distinguish from wild-growing varieties based on leaf shape and size. The researchers used genetic analysis to estimate when different coca species and varieties originated, suggesting a longer evolutionary history than previously thought.
A new study introduces a novel hypothesis that digital technologies affect human sociality and mental health, particularly among youth. The Disembodied Disconnect Hypothesis suggests cultivating rich personal relationships in face-to-face communities to counterbalance disembodied digital interactions.
Women's funding campaigns on Dutch platforms are 20% shorter in duration compared to men's and couples', according to a new study published in PLOS ONE. This suggests that crowdfunding may be a more favorable platform for female entrepreneurs.
A new study found that prenatal ozone exposure significantly raises BMI and weight-for-age Z scores in children, increasing the risk of obesity. The research suggests that stringent air quality regulations are needed to protect children's health and development.
Researchers have found the nearest massive black hole to Earth, located at the center of Omega Centauri, a galaxy that was swallowed by the Milky Way. The discovery provides insight into the formation history of galaxies and confirms long-held suspicions about the existence of intermediate-mass black holes.
A new catalyst with a lead coating enhances the performance of a nickel-based hydrogen evolution reaction catalyst, increasing efficiency and resisting reverse current. This breakthrough could improve the durability of alkaline water electrolysis systems and support a green hydrogen economy.
The study reveals that hiPS-CMs induce a limited immune response but are rejected around 17-24 days after transplantation due to CD8+ T cells. Depletion of CD8+ T cells or treatment with tacrolimus prolongs sheet survival, highlighting the pivotal role of these immune cells.
Researchers developed a method to analytically express the performance of wireless communication systems when using reconfigurable intelligent surfaces (RIS). The model accurately predicted the effects of RIS on improving radio wave propagation environment, providing a useful guide for positioning RIS to receive stronger signals.
The study provides a detailed analysis of high-grade glioma molecular characteristics, revealing shifts in gene expression and tumour microenvironment. Longitudinal samples revealed unique opportunities to observe tumour evolution, shedding light on genetic and epigenetic events associated with recurrent disease.
Researchers have identified a phage-derived enzyme that targets E. faecalis biofilms, reducing the severity of acute graft-versus-host disease in patients. The enzyme exhibits narrow-spectrum activity against E. faecalis and effectively lyses biofilms without affecting other bacteria.
Researchers investigate chemical modifications to genetic regulation mechanisms, finding that Set8 controls gene activity through a mechanism other than histone modification. This study refines our understanding of genetic regulation relevant to human diseases like cancer.
Co-circulation of Mayaro and chikungunya viruses has been observed in Roraima, Brazil's northernmost state, according to a recent study. The finding highlights the need for more effective epidemiological surveillance in the region. Deforestation and human activities may facilitate transmission in urban areas.
A study by Bayes Business School and universities found that pitches for radical ideas work better with concrete explanations, while progressive ideas benefit from abstract 'why' style pitches. Entrepreneurs should tailor their approaches to match the idea's novelty to attract investment.
New research suggests that the plague may have contributed to the population decline of Stone Age farmers in Scandinavia and Northwestern Europe. Analysis of ancient DNA from bones and teeth found that 17% of individuals were infected with the plague, indicating its common presence during the late Stone Age.
Researchers have designed a novel Co-STAR receptor that combines genetic components of four types of immune cells to recognize and fight cancer cells. In laboratory studies, the Co-STAR receptor induced a sustained anti-tumor response against human cancer cells, leading to long-lasting remissions in mouse models.
Researchers at Amsterdam UMC have developed a prediction model that can forecast cognitive decline in Alzheimer's patients with mild cognitive impairment or dementia. The model provides an indication of the disease course over 5 years and has potential for use in a user-friendly app, aiding doctors in discussing prognosis with patients.
A new study from Keck Medicine of USC reveals a startling disparity in the frequency of liver disease among transgender individuals, with double the prevalence of cirrhosis compared to cisgender adults. The study highlights the need for more supportive, preventive care and emphasizes the importance of early prevention.
Scientists have discovered a new defense mechanism in bacteria that uses cell-to-cell communication to 'warn' unaffected bacteria about potential threats, allowing them to shield themselves and spread the warning signal. This mechanism has been found to be effective against various antibiotics and toxins.
A new generation of ecological models is required to understand how ecosystems respond to global and local changes, says Dr Alice Johnston. These models must be widely applicable across environmental research to support policy decisions.
Researchers have identified microproteins exclusive to liver tumors that can stimulate the immune system against cancer cells. These small molecules, generated from previously non-coding genes, could be used to develop new treatments, including vaccines that stop or reduce tumor growth.
Global challenges like access to care and widening social inequalities are addressed by the landmark WHO resolution, which outlines clear government responsibilities for social participation. The resolution aims to empower communities and foster partnerships to create healthier systems.
A new species of extinct crocodile relative, Benggwigwishingasuchus eremicarminis, has been discovered in Nevada, USA. The species reveals that pseudosuchian archosaurs ruled the shores across the Middle Triassic globe between 247.2 and 237 million years ago.
A research team led by Professor Yow Wei Quin found that implementing cognitive training in a dual-language mode improves the cognitive abilities of older adults. The Dual-Language Intervention in Semantic memory – Computerised (DISC) tool is a game-based application designed to encourage independent play and improve cognitive function.