Researchers investigated the sustainability of ancient Roman concrete, finding that reproducing its recipe would require comparable energy and water, emitting similar CO2. However, Roman concrete's heightened durability might make it a more sustainable option due to reduced maintenance needs, potentially reducing environmental impact.
A new study suggests that both defendants and complainants are equally susceptible to memory errors in sexual assault cases. The research found strong misinformation effects, with individuals in both roles equally likely to misremember details of the events leading up to the sexual encounter.
A new study has found a strong correlation between the sentiment of Instagram images and user sentiments on social media, particularly for anti-war images. The research suggests that social media images can significantly influence public opinion on sociopolitical events, with notable effects observed in comments from users.
Researchers found that treehoppers' unusual morphologies increase their sensitivity to static electricity, potentially helping them detect predators. The study provides a new insight into the possible role of electrostatic sense in driving organismal morphology evolution.
Researchers introduced a novel approach for fabricating high-performance near-infrared perovskite light-emitting diodes (NIR-PeLEDs) using triple-source thermal co-evaporation. This strategy directly forms the black-phase α-FACsPbI3 perovskite, overcoming phase instability and surface roughness issues.
A national survey conducted by Washington State University researchers found that young men with a
A large-scale study in China found that nearly one-quarter of pregnant women experience depressive symptoms, highlighting the need for effective preventive and management strategies. Socioeconomic factors and partner support play crucial roles in the development and risk reduction of antenatal depression.
This meta-analysis found that FMT combined with ICIs resulted in improved objective response and disease control rates, with an acceptable safety profile. Subgroup analysis revealed a significant association between the combination of anti-PD-1 and anti-CTLA-4 therapies and higher overall response rates.
Researchers developed a new computer modelling method that adheres to a cricket's physical characteristics, predicting precise vibration patterns and song frequency. The study used preserved specimens and wetting the wing with water to recover correct frequencies, providing a more reliable way of reconstructing cricket acoustic function.
Research reveals obesity's role in cancer development through mechanisms like chronic inflammation, hormonal disorders, and microbial dysbiosis. Lifestyle changes and targeted treatments hold potential in preventing obesity-related cancers.
A new gene therapy intervention administered at birth provides multi-year protection from HIV infection, useful in areas lacking access to antiretroviral drugs. The treatment uses a common gene therapy shuttle to produce an HIV-specific broadly neutralizing antibody, showing no side effects and long-lasting protection.
A study published in Neurology found that women with multiple sclerosis are less likely to receive disease-modifying drugs than men, even when accounting for pregnancy and postpartum periods. The study suggests that women's reluctance to use these treatments may be a factor in the disparity.
Researchers reanalyzed ancient honey residue from Greek shrine jars using modern techniques and determined its likely origin. The findings suggest the presence of ancient honey, but other bee products may also be present.
Researchers at Tsinghua University Press have developed a novel molecular-scale strategy to create high-temperature EMW absorbing materials with temperature-insensitive permittivity. The multi-heterointerface lightweight ceramics demonstrate outstanding performance in absorbing EMW across a wide temperature range.
A study published in Clinical Gastroenterology and Hepatology found that around one in five people with Lynch syndrome develop a second colon cancer over an average of 7.9 years. The risk depends on the genetic subtype, with changes in MLH1 or MSH2 genes increasing the likelihood of a second tumor.
The research develops a comprehensive family assistant capable of performing various tasks like picking up toys and fetching items. The robot uses YOLOv11 object recognition and flexible gripper to recognize objects of varying sizes and weights with high accuracy.
This book provides a beginner-friendly resource on the impact and evolution of decentralized networks, highlighting their applications in healthcare, supply chains, agriculture, climate monitoring, and education. The authors emphasize sustainability, data security, and ethical tech adoption.
An international survey of over 300 adults suggests that males born in summer are potentially more prone to depression. Female study participants did not show a similar association with depression.
A low-cost 'SimpleSilo' device mimics commercial silo bags without high cost, using inexpensive materials and easy-to-source supplies. The device demonstrated comparable performance to commercial silo bags and can be assembled by hospital staff in under an hour.
Researchers found that voting behavior did not significantly change despite suspension of rights like freedom of assembly and movement. The estimated drop in vote share was between 0.8 and 1.7 percentage points, statistically insignificant.
Fecal microbiota transplantation (FMT) shows promise in enhancing cancer immunotherapy outcomes, with some studies demonstrating remarkable improvements and others showing no benefit. The success of FMT depends on multiple factors, including donor selection and specific bacterial communities being transferred.
Researchers found that a protein called intersectin separates message-bearing bubbles in brain cells at the synapse, enabling the brain to decide when to use them. This discovery advances our understanding of memory formation and learning, and may lead to new treatments for cognitive disorders like Down syndrome and Alzheimer's disease.
Gemini achieved highest accuracy, followed by Claude-3-opus and GPT, with accuracy varying significantly across single-image tasks and continuous slices. Simplified prompts improved diagnostic performance, but Gemini and GPT struggled with normal image recognition.
A large census of dikes in the Netherlands revealed that more bee species live on dikes than previously thought, with 154 different species found. The researchers found that flower-rich dikes attract many more bees, especially endangered species, due to the variety of plants and nesting sites.
A recent study reveals that surgeons in the United States have a disproportionately high mortality rate compared to other highly educated professionals, including nonsurgeon physicians. The study suggests that factors such as work environment and lifestyle may contribute to this disparity.
The HELO survey reveals a population seeking optimal health and lifespan, yet lacking the necessary knowledge and access. Key findings include strong public interest in Healthy Longevity Medicine clinics across all age groups, with older adults showing clear enthusiasm for preventive care.
A recent study identified four genes associated with treatment resistance to immunotherapy in melanoma patients. The genes, CD24, NFIL3, FN1, and KLRK1, were found to be linked to mechanisms of immune evasion and suppression of the inflammatory response. Patients with high expression of these genes had significantly lower overall survi...
Researchers develop compact, noninvasive imaging system combining LC-OCT and Raman microspectroscopy to examine skin cancer structures and chemical composition. The AI model achieves high classification accuracy for basal cell carcinoma and other types, offering new insights into cancer development and behavior.
The University of Copenhagen is excited to announce Zuber Lawler as a sponsor of the 12th Aging Research & Drug Discovery Meeting. The conference will bring together academia-pharma-startup-investor partnerships to discuss advancements in aging research and its applications.
A new study led by University of Waterloo researchers found that female pilots tend to make fewer flight control errors under stress, despite similar visual attention patterns. The findings challenge gender bias in aviation performance and suggest a need for more inclusive pilot training and evaluation systems.
A new research paper found that epigenetic aging is linked to cognitive decline in midlife, with twins experiencing a larger drop in IQ scores if they had grown up in families with lower socioeconomic status. This study provides new evidence for the impact of childhood adversity on brain aging.
Deep Origin will host two presentations at ARDD 2025, showcasing its AI-based models for drug discovery and longevity. The company aims to enable creation of virtual cells and deeper understanding of biological function.
A global study found that cancer immunotherapies carry a hidden risk: cholestasis, a serious liver condition. Researchers urge aggressive monitoring of liver function, particularly in younger adults and women.
Researchers at McMaster University have developed a promising new treatment for liver cancer by targeting metabolism in tumours. The discovery, published in Nature, shows that inhibiting an enzyme called ATP citrate lyase can enable the immune system to kill liver cancer cells, particularly through B cell-mediated responses.
A new study reveals that large language models can generate convincing but biased peer reviews, nearly indistinguishable from human writing. The AI excelled at generating persuasive rejection comments and fabricating reasons to cite unrelated studies, posing a serious risk to the integrity of scientific publishing.
A global analysis of CAR-T cell therapy found a significantly increased risk of developing secondary cancers, particularly T-cell lymphoma and myelodysplastic syndromes. The median onset of these cancers occurred much earlier in CAR-T recipients compared to those not receiving the treatment.
Researchers found that hot days increase emergency department visits and hospitalizations, while cold days are associated with fewer deaths, particularly among older adults. The study suggests that health policy needs to account for temperature-related impacts across different age groups.
Senescent T cells exhibit genomic instability, protein imbalance, and mitochondrial dysfunction, impairing immune function and recognizing tumor antigens. The presence of senescent T cells is associated with poor prognosis and reduced immunotherapy efficacy.
A new online tool calculates a person's 'heart age' based on cardiovascular disease risk factors, revealing significant gaps among certain groups. On average, women had a heart age of 55.4, while men had an average heart age of 56.7, with disparities found among those with lower incomes or education.
A team of geophysicists from ETH Zurich and SUSTech, China, used computer models to simulate whether a completely liquid core could generate a stable magnetic field. Their simulations showed that the Earth's magnetic field was generated in the early history of the Earth in a similar way to today.
A study published in PLOS found that urban exposure significantly increases the risk of obesity among middle and old-age migrants in India. The longer they stay in cities, the greater the risk of obesity.
A multi-institutional team has proposed updates to national guidelines to remove race-based assessments from lung function testing. The authors highlight the need for a more equitable evaluation system, warning against overreliance on objective cutoff-based criteria. Several healthcare systems have already shifted to race-neutral refer...
A team of international researchers has taken an unprecedented image of the heart of the OJ 287 galaxy, revealing a curved segment of the plasma jet. The discovery provides new insights into the extreme conditions surrounding supermassive black holes and their role in shaping the jets.
A new study found a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia. Individuals with long COVID face significantly higher rates of these disorders, alongside worse mental health and quality of life.
Bloomsbury is introducing Altmetric Explorer to track social attention and sharing of its publications, providing insights into reach, impact, and value. The tool will inform future editorial strategy and improve reader engagement.
A large-scale study found that zoos are often breeding endangered animals in skewed sex ratios, which can limit genetic diversity and increase the risk of extinction. The research highlights the need for zoos to collaborate and share data on their animal populations to manage conservation efforts effectively.
Researchers found that people who experienced malnutrition early in life may have survived threats like plague at greater rates until young adulthood. However, this survival advantage could drop significantly when entering middle and late adult years.
Long-term heat exposure negatively impacts students' cumulative learning, with complex tasks more affected than simpler ones. Lower socioeconomic groups face disproportionately greater impacts, underlining critical inequalities.
At ESC Congress 2025, over 40 pivotal studies will be presented, addressing major clinical questions and unmet needs in global cardiovascular care. The trials focus on innovative treatments for conditions like chronic Chagas cardiomyopathy and hypertrophic cardiomyopathy.
Recent scientific advances aim to enhance the efficacy of psychosocial treatments for mood and psychotic disorders, according to Dr. Marc J. Weintraub's upcoming webinar. Innovative approaches discussed include a mobile app adjunct therapy for adolescents at risk and psilocybin integration for adults with major depression.
Researchers discovered that cancer cells have a defensive mechanism to repair DNA damage and survive physical stress by activating mitochondria to pump in extra ATP. This finding could lead to new therapeutic approaches by targeting the mechanism's underlying scaffold.
A study found that users who exchanged daily walking steps for digital train tickets increased their walking by an average of 626.2 steps/day. Those using shopping coupon incentives walked 715.2 steps/day more on average than non-users. The results suggest effective promotion of active travel through well-designed mHealth apps.
The Brain & Behavior Research Foundation recognizes Joseph J. Taylor, Ash, and Harnett as recipients of the 2025 Klerman and Freedman Prizes for their outstanding work in mental illness research. Long Li receives the Freedman Prize for his basic research contributions to understanding depression and PTSD.
The new book highlights the transformative role of artificial intelligence (AI) and machine learning (ML) across various domains, including mechatronics, cybersecurity, digital health, and automation. Readers will gain practical insights into AI-based techniques in power systems, social media management, and healthcare diagnostics.
A recent study by UCLA researchers found that introducing new genetic variation from Texas reduced the influence of harmful mutations in Florida panthers, improving their fitness. However, the effect of this intervention may be temporary, and continued protection is needed to preserve the subspecies.
A team of astronomers captured a detailed image of a ribbon-like jet emerging from the heart of OJ 287, revealing extreme energy and motion near the black hole. The study sheds new light on supermassive black holes and their powerful jets, potentially offering clues to binary black hole mergers.
This book presents innovative nanomaterials for efficient pollutant removal from wastewater, reducing energy consumption and promoting eco-friendly treatment outcomes. It explores emerging trends and future directions in nanotechnology-based purification, providing practical insights for researchers and professionals.
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV. The treatment uses an adeno-associated virus to deliver instructions to muscle cells, which produce broadly neutralizing antibodies capable of neutralizing multiple strains of HIV.
Researchers from Trinity College Dublin develop a method to harness structural colour using microfabrication technique, enabling ultra-sensitive materials for environmental sensing and biomedical diagnostics. The breakthrough also paves the way for next-generation medical sensors that can track biochemical changes in real-time.
A UNLV study uses an mRNA cocktail to selectively route to the pancreas, reducing the risk of immune responses and side effects. The breakthrough offers new hope for treating pancreas-related diseases, including cancer and diabetes.
A team of researchers at Kyoto University has successfully developed a method to calculate the vibrations of black holes using exact WKB analysis. The approach reveals complex patterns in spiraling waves, enabling precise capture of frequency structure and bridging theoretical predictions with observational data.
A large-scale genetic study found ten new regions associated with the ability to detect specific odours, with three showing sex-specific effects. The research also uncovered a link between the risk of Alzheimer's disease and the sense of smell, highlighting the interconnectedness of these senses.
The EnIGMA framework demonstrates superior performance across multiple benchmarks, solving more than three times as many cybersecurity challenges as previous AI agents. The research also identifies a previously unknown phenomenon called 'soliloquizing,' where the AI model generates hallucinated observations.
A study in the Canadian Journal of Cardiology finds that delaying chest compressions to prevent tongue swallowing can lead to poor outcomes, including death or severe brain injury. The research exposes media-fueled misconceptions and emphasizes the importance of immediate CPR training.
Reinforcement learning world models are introduced as a promising tool for modeling complex atomic level changes in catalyst surfaces. The review presents advancements in using Dreamer-based architectures and multi-objective optimization strategies to address long-standing challenges in catalytic surface modeling.
Scientists generate collective molecular vibrations in a liquid by placing an electron ultrafast. These vibrations govern the electric behavior of the liquid and can be tuned to adapt its properties. The study reveals new insights into polar liquids' dynamics.
This article reviews bronchiectasis phenotypes and endotypes, exploring their impact on disease management and treatment strategies. Recent research has identified distinct inflammatory endotypes, guiding targeted therapies and improving patient outcomes through personalized approaches.
A recent study published in New Phytologist reveals a crucial gene necessary for plant reproductive structures. The gene, named SHOT GLASS, is found to regulate the development of air chambers and sexual organs in liverworts, a model organism for studying plant reproduction.
The Fibrosens project aims to develop a novel platform for real-time monitoring of fibrosis biomarkers in muscular dystrophies using nanoplasmonic sensors. The project will enable faster and cheaper testing of anti-fibrotic drug candidates, as well as personalized drug screenings for patients with specific mutations.
A recent study by Drexel University researchers analyzed 24 coastal New Jersey communities' communication of climate-related hazards. The analysis found wide variation in the number and extent of mitigation actions taken, with stormwater management and road improvements being the most frequently mentioned projects.
Researchers discovered that Candida albicans can persist in the mouse gut for at least 58 days without causing harm, and treatment with anti-fungal medication only reduced its presence. The fungus's ability to colonize was linked to the production of candidalysin and adhesins.
A multicenter study found influenza-associated acute necrotizing encephalopathy (ANE) carries a high risk of morbidity and mortality in children, with a 27% mortality rate. Survivors often experience neurological difficulties, emphasizing the need for rapid treatment and vaccination to prevent ANE.
Researchers developed an open-source software tool, Phoenix, to simulate light behavior in quantum systems, solving wave equations in record time without high-performance computing expertise. The program is up to a thousand times faster and 99.8% more energy-efficient than conventional tools.
This study uses AI to pinpoint optimal synergies in combination therapies, slashing experimental costs and accelerating discovery by up to 7.2% in accuracy.
Researchers found that high rates of coronary heart disease were linked to poverty, limited healthcare provider availability, and low broadband access. However, some counties with similar challenges reported lower-than-expected cardiovascular outcomes, suggesting the need for tailored strategies to address health disparities.
Cancer-associated fibroblasts (CAFs) exhibit paradoxical effects on immunotherapy, sometimes hindering and other times helping to control tumors. Research identifies specific CAF subtypes that enhance or suppress immune cells, offering promising targets for therapies.
A new study by Mass General Brigham found that states with flavored e-cigarette ban policies experienced a significant decline in e-cigarette use among young adults and adults, but a slower decrease in cigarette smoking rates. This mixed impact raises concerns about the unintended consequences of flavor bans.
Researchers from Japan studied DJ-1's catalytic mechanism, revealing key amino acids involved in cPGA hydrolysis. Mutations in these residues revoked cPGA hydrolase activity, confirming the pathophysiological implications of DJ-1.
A new AI-based technology analyzes mammograms to predict a woman's five-year breast cancer risk, outperforming standard methods by 2.2 times. The system provides an absolute risk score comparable to national incidence rates, enabling targeted prevention and early detection.
A $5.5 million federal grant will support clinical trials to treat fragile X-associated tremor/ataxia syndrome (FXTAS). The project aims to develop accurate outcome measures for future trials, ensuring patients and caregivers have a say in what matters most.
Researchers found that solar energy delivers the biggest climate payoff in certain US regions, with California and Florida seeing significant CO2 reductions. A 15% increase in solar power led to a reduction of up to 147.18 metric tons of CO2 in California alone.
Researchers have found electrolytes with boron additives can mitigate critical challenges of lithium metal batteries, including lithium dendrite formation and low Coulombic efficiency. The boron additives also improve the specific discharge capacity and high-rate performance of lithium-ion batteries.
Researchers from Italy developed a conductive biopaste to accelerate coral growth and a natural healing patch to target antibiotic delivery to diseased corals, both showing promising results in laboratory tests.
A study published in the Royal Society's Proceedings B found that closely related bat and bird species share the same habitat due to their shared evolutionary history. This challenges previous ideas about competition driving species apart, suggesting that animals with similar needs tend to group together in suitable habitats.
A new study reveals that a slowdown in the Atlantic Ocean current could halve annual precipitation in tropical regions, drying out rainforests and upending ecosystems. Climate change is predicted to weaken the current, leading to significant reductions in rainfall over Central America, the Amazon, and West Africa.
Researchers at the University of Basel have developed an engineered enzyme to precisely build complex molecules, such as pharmaceuticals and fine chemicals. The new approach uses metal hydride hydrogen atom transfer (MHAT) chemistry with enzymatic catalysis to produce three-dimensional molecules with single-handed configuration.
The CPADS web tool integrates data from GEO, TCGA, and GDSC databases to analyze gene expression changes, correlations between genes or drugs, and pathway enrichment in cancer samples. L1CAM was identified as a potential drug resistance target in non-small cell lung cancer through CPADS analysis.
The FDA has authorized artificial intelligence devices for Alzheimer's and related dementias despite limited demographic data. Disease status, age, sex, and race were reported for fewer than half of devices, raising concerns about real-world generalizability.
Researchers find large language models (LLMs) can predict drug-target interactions more accurately. LLMs are advancing drug discovery by optimizing molecule design and improving model reliability.
A Stanford Medicine-led report found that children with rare flu complications like influenza-associated acute necrotizing encephalopathy (ANE) need prompt treatment to survive. The condition causes brain swelling and a runaway immune response, leading to fatal outcomes if left untreated.
Researchers have developed a three-dimensional imaging method to distinguish between two fundamental processes by which light is transformed into electric current in quantum materials. The breakthrough could lead to improvements in solar energy systems and optical communications technology.
This book presents cutting-edge approaches to combat cancer, including exosomal delivery systems, CRISPR/Cas9 gene editing, and immunotoxin therapy. Natural compounds are also examined for their anticancer potential.
A cohort study found that stroke center certification decreases racial disparities in treatment for white patients within the same hospital, but such disparities remain for Black patients. This suggests continued systemic inequalities in stroke care settings.
A new study published in Ecology reveals traditional methods of tracking animal movement may be underestimating the actual distance travelled by whales, particularly for marine species.
The new book provides a comprehensive overview of engineered nanomaterials' interactions with biological systems, driving breakthroughs in biomedical applications and environmental sustainability. It explores critical applications in sustainable technologies, including bioremediation and heavy metal adsorption.
University Hospitals has received American Heart Association quality achievement awards for ensuring stroke patients receive best practices and life-saving care. The institution prioritizes early detection and treatment to improve survival, minimize disability, and accelerate recovery times.
A large meta-analysis of over 800,000 participants shows that high adherence to the Mediterranean Diet, Alternative Healthy Eating Index, and Dietary Approaches to Stop Hypertension reduces type 2 diabetes risk across diverse ethnic groups. These three diets have been recommended for general health and their potential benefits were fou...
Researchers map the path from liver fibrosis to cancer, revealing how scarred liver tissue becomes a breeding ground for tumor growth. Key findings include the role of hepatic stellate cells and dysregulated signaling pathways in remodeling the liver into a pro-tumor environment.
Researchers at WashU Medicine discovered that mast cells stand guard at tiny gates through which fluid waste leaves the brain, mounting a response when a pathogen is detected to close the gates and prevent invaders from entering. Enhanced mast cell activity before an infection reduced bacterial load.
A study merged rice growth models, genome-wide association studies, and machine learning to predict flowering time with high accuracy. The approach integrated climate indices and showed promise for precision agriculture and molecular breeding.
A new study uses GenAI models to extract pathological features for lung adenocarcinoma grading and prognosis, achieving striking accuracy and consistency. The research team discovered 11 key histological features and 4 clinical variables that provide a comprehensive risk assessment for patients.
Researchers found surprisingly high concentrations of small-diameter microplastics in air samples from their homes and cars, estimating adults inhale 68,000 particles per day. The study suggests health risks due to inhalation of lung-penetrating microplastics may be higher than previously thought.
Researchers at Max Planck Institute for Nuclear Physics have successfully detected antineutrinos from a nuclear reactor using the CONUS+ experiment. The detection uses Coherent Elastic Neutrino-Nucleus Scattering (CEvNS), allowing for improved sensitivity to new physics beyond the Standard Model.
A coordinated approach is needed to address the scientific value of trial representation of the intended use population. The study aims to provide a strategic framework to ensure scientific validity by operationalizing broad representation at all levels.
The study introduces a modified electrolyte LPSC-5%Li3PO4 with enhanced chemical/electrochemical stability, demonstrating an ionic conductivity of 5.71 mS cm–1 and suppressing dendrite growth. The PO43- doped electrolyte exhibits excellent mechanical stability and good compatibility with lithium metal.
The study identified ZmMPK3 as a positive regulator of salt stress response in maize. The ZmMPK3-ZmGRF1 module enhances cell proliferation under saline environments, promoting maize growth.
A new study by USC researchers reveals that social media susceptibility clusters among users' friends, leading to a phenomenon called the Susceptibility Paradox. This pattern is strongest in influence-driven sharing, where users are more likely to post content if their friends have done so before.
A new study led by Harvard T.H. Chan School of Public Health found that increasing solar power generation in the US by 15% could lead to significant cuts in CO2 emissions. The researchers pinpointed regions where clean energy investments return the greatest climate dividends and demonstrated the value of coordinated clean energy efforts.
The THER web tool analyzes hypoxia-associated transcriptomic data without programming skills, presenting results via volcano plots, heatmaps, and tables. Experimental validation confirms THER's reliability, revealing broad impacts of hypoxia on drug efficacy across tumor types.
A low FODMAP diet has been shown to improve colonic barrier function and reduce mast cell activation in patients with IBS-D. The study found that the diet reduced symptoms of diarrhea and abdominal pain, and improved intestinal permeability.
Researchers at the Korea Institute of Science and Technology (KIST) have developed a high-throughput multiplexed gene and cell doping analysis technique using CRISPR-Cas technology. This breakthrough offers superior performance in detecting exogenous genes, demonstrating potential applications in sports ethics and fairness, as well as ...
The article discusses how intratumoral microbial metabolites modulate immune cell function, influencing cancer immunotherapy outcomes. The review examines the impact of glucose, amino acids, lipid, and other metabolites on the tumor microenvironment and immunotherapy efficacy.
A study from the University of Georgia found that lions and hyenas tend to stay near roads with less tourist traffic, particularly during the dry season. The animals often visit waterholes for drinking or hunting, but hyenas may avoid areas with high competition from lions.
A decade-long study reveals that the source of dietary fat, not adiposity itself, is the primary factor influencing tumor growth in obese mice. High-fat diets derived from animal fats compromise anti-tumor immunity and accelerate tumor growth, while plant-based fats have a neutral effect.
A study evaluates a city-level warning system based on wastewater data to detect COVID-19 outbreaks early. The proposed system offers broader coverage, earlier outbreak detection, and lower costs compared to clinical surveillance.
Researchers at Mass General Brigham found larazotide effective in treating children with multisystem inflammatory syndrome in children (MIS-C), a rare but serious condition. The oral drug strengthened intestinal barriers to limit SARS-CoV-2 viral particle entry, resolving symptoms and improving recovery.
A large study examines 17 years of Medicare hospitalization claims and major flooding events, finding increased rates of specific health issues among older adults. The research highlights the need for targeted outreach, robust evacuation planning, and improved access to medical services to protect public health during climate change.
Researchers found that combining lavender essential oil with its own hydrosol effectively preserves skin-care emulsions against bacteria and fungi. The simple pairing kept counts below European Pharmacopoeia limits, even at high temperatures.
A group of leading scientists published a paper providing a decision tree to select the most appropriate quantification techniques for postbiotics. The framework helps ensure accurate characterization and reproducible manufacturing of postbiotic products.
A new study has found that US nitrous oxide deaths have increased by more than 500% between 2010 and 2023, primarily driven by recreational misuse. The researchers warn of the dangers of inhalant use, particularly among young people, highlighting the need for public awareness and intervention to prevent harm.
A new study reveals that cyberstalking is increasing at a faster rate than traditional stalking, with nearly half of victims not perceiving it as a crime. The researchers call for improved public education, clearer legal definitions, and enhanced support services to address the growing threat of cyberstalking.
Researchers propose reforms to nature-based climate actions by accounting for feedbacks and ensuring outcomes that wouldn't have happened otherwise
Researchers found measurable changes in brain signals responsible for motor control and movement after 12 dynamic cycling sessions. The study suggests long-term exercise programs could have wider restorative effects on the brain signals of Parkinson's Disease patients.
A new study published in PNAS found that prolonged and repeated exposure to GABA anesthetic agents in infants under two months leads to accelerated visual cortical development. This may suggest the use of non-GABA-active anesthetics for newborns, as a large multicenter clinical trial is currently underway.
Researchers at ETH Zurich and Stanford University quantified the number of molecules produced by gut bacteria that reach the human body daily. This knowledge helps understand how the gut microbiome influences health and behavior.
Researchers at La Jolla Institute for Immunology investigate the fundamentals of allergy immunotherapies by examining T cells in children with cockroach allergies, finding that dosage and underlying response don't affect treatment efficacy.
Researchers discovered that metformin's ability to lower blood sugar depends on turning off a small protein called Rap1 in the brain. The study found that low doses of metformin can significantly drop blood sugar levels even with thousands of times smaller doses than typical oral administration.
A case series of children with influenza-associated acute necrotizing encephalopathy highlights the condition's severe impact on young, previously healthy children. The study emphasizes the need for prevention, early recognition, intensive treatment, and standardized management protocols to address this critical public health concern.
State-of-the-art LLMs can assist radiologists in interpreting chest CT reports, reaching a 75% accuracy rate across common diseases. Fine-tuning and prompt engineering improve model performance, with GPT-4 and Qwen-Max showing exceptional strength.
A recent study from the University of California, Riverside, and the University of Wisconsin-Madison emphasizes the need for culturally responsive approaches to support healing among Latina college students who have experienced intimate partner violence. Resilient coping and social support were found to be strong predictors of well-being.
The journal is seeking high-quality submissions that explore the potential of voice and speech analysis in diverse medical applications. Submissions focus on acoustic and voice analysis techniques, voice or vocal phenotyping, and vocal biomarkers in health and medicine.
Researchers discovered that a type of HPV commonly found on the skin can directly cause a form of skin cancer called cutaneous squamous cell carcinoma when immune cells malfunction. The study's findings suggest that other people with defective T-cell responses may also be susceptible to cancer caused directly by beta-HPV.
Recent AI-based models, such as Asian Prostate Cancer Artificial Intelligence and Galen Prostate, optimize screening and reduce unnecessary biopsies. These models use multimodal clinical parameters and convolutional neural networks to detect prostate cancer and identify aggressiveness of cancer cells.
Research examines undercarboxylated osteocalcin's impact on diabetes, osteoporosis, Alzheimer's disease, and other conditions like NAFLD and depression. Glu-OCN's influence on glucose homeostasis, lipid metabolism, and cholesterol metabolism is discussed.
The cichlid fish Perissodus microlepis has an unusual head shape due to bilateral symmetry breakdown, and its genome analysis reveals multiple genes contribute to this asymmetry. Behavioral experiences also influence the preferred direction of hunting behavior, reinforcing both genetic and morphological asymmetries.
Researchers found biochar improved soil's ability to hold nutrients and moisture, giving cotton plants better growth conditions. Biochar also helps improve water quality by keeping nitrates in the soil and out of groundwater.
Researchers develop machine learning models to analyze sparse digital footprints and forecast depressive relapses or manic episodes with clinical-level accuracy. The approach uses GPS-derived social withdrawal and erratic typing patterns to predict bipolar episodes 24 hours in advance.
The São Paulo School of Advanced Science in Systems Change and Sustainability brings together leading academics to discuss cutting-edge knowledge on sustainable transformation. Applications will be selected based on résumé, academic transcript, letters of recommendation, and proposal submission.
A new tool has been developed to improve the security of small-scale business transactions, utilizing blockchain-powered smart contracts. The tool provides a clear record of agreements and obligations, ensuring that businesses are paid and customers receive services as promised.
Researchers found that common respiratory infections like COVID-19 and influenza can awaken dormant breast cancer cells in the lungs, leading to a massive expansion of metastatic cells. The study suggests that individuals with a history of cancer may benefit from taking precautions against respiratory viruses.
Researchers used machine learning to analyze 3,430 drugs and identified 29 new lipid-lowering candidates. The predictions were validated using clinical data, mouse experiments, and molecular docking, offering a potential solution for patients with hyperlipidemia.
A team of researchers at the University of Toronto has identified a protein, Shikimate kinase-like 1 (SKL1), that enables land plants to convert light into energy through photosynthesis. This discovery holds promise for improved herbicides and increased efficiency of photosynthesis in food crops.
A scoping review of 66 studies suggests distinct physiological underpinnings for different dimensions of psychopathy and its impact on facial emotion recognition. Oxytocin is proposed to play a role in modulating this skill.
A global study on early childhood education policies found that social skills are rarely included in educational programs, despite their importance for personal and professional lives. The study highlights the need to promote citizenship skills and address structural factors influencing educational success.
Researchers developed a protective coating called PDAI2 to shield perovskite solar cells from space damage. The coating helps the cells survive in harsh conditions, allowing for longer operation times and improved efficiency.
Researchers discovered an 85m-deep crater and 90 million cubic metres of water flooded out of a subglacial lake, fracturing the ice above and creating a massive flood. The study highlights the need to better understand how often subglacial lakes drain and their impact on the surrounding ice sheet.
A Safe Systems Approach emphasizes that road users, designers, operators, policymakers, administrators, and healthcare professionals all have a role to play in reducing fatalities. By adopting this approach, countries can realize significant success in eliminating roadway deaths, but full commitment from stakeholders is necessary.
Researchers introduce a novel electrocatalyst design strategy using chemical fermentation, creating a multilevel porous carbon architecture embedded with Ni–Fe alloy nanoparticles. This approach achieves ultra-efficient oxygen evolution reaction performance, with a record-low overpotential of 165 mV at 10 mA cm−2.
A UNIGE team has identified a new brain mechanism responsible for modulating sensory signals. This discovery reveals a previously unknown form of communication between the thalamus and somatosensory cortex, which could explain perception variations and open up new avenues for understanding mental disorders.
A pilot cohort study assesses the efficacy of a microfluidic-based point-of-care bilirubin measurement system in detecting bilirubin levels with high accuracy, comparable to standard clinical laboratory methods. The device's miniaturized optical sensing module and microfluidic test cartridge enable scalable adoption and portability.
Researchers from the Institute of Physics of the Czech Academy of Sciences studied the biological effects of permanent magnetic fields and found that their distribution in space plays a critical role in healing. The study's detailed field maps offer practical guidance for optimizing magnet use in medicine and magnetobiology.
Researchers at the University of Cincinnati are developing drones that can optimize wind in real time using a principle called dynamic soaring, inspired by albatrosses. The project aims to turn wind into an advantage for drones, reducing energy loss and increasing efficiency.
The American Association for the Advancement of Science (AAAS) has launched a new journal, Civil Engineering Sciences, which aims to publish interdisciplinary and cutting-edge works on discoveries and innovations in civil engineering. The journal will promote future reform and innovation in civil engineering science and technology.
Researchers have developed a predictive tool that can identify patients with nasopharyngeal carcinoma most likely to benefit from radiotherapy. The model uses transcriptomic data and machine learning to evaluate 113 algorithm combinations, identifying an 18-gene signature associated with radiosensitivity.
Researchers at Oak Ridge National Laboratory have developed a new method to improve the strength and conductivity of dry-processed battery electrodes using long carbon fibers. The resulting batteries exhibit faster charging and discharging rates, reduced risk of overheating, and lower production costs.
Researchers at the University of São Paulo propose an inelastic DM model that interacts with ordinary matter through a vector mediator. This interaction could open a new window for dark matter research, providing a more precise understanding of its properties and behavior.
Scientists from the University of Kansas developed a technique to track ultra-peripheral collisions between protons and ions, resulting in the creation of gold momentarily. The discovery was made possible by studying photon-photon collisions, which are incredibly clean events with almost nothing else produced.
Researchers at Kyoto University discovered that crested serpent eagles possess a unique genetic mutation allowing them to resist the toxins of invasive cane toads. The eagle's toxin resistance is attributed to the same amino acid sequence as the Siamese red-necked keelback snake.
Researchers found that ground acceleration from moonquakes can shift lunar landscapes and threaten stability of future missions. The study assesses damage risk using new models of quakes and finds a one in 20 million chance of a potentially damaging moonquake occurring near an active fault.
A new study by Children's Hospital of Philadelphia researchers has found that eye-tracking metrics can help identify concussion-related vision disorders in patients with persisting post-concussive symptoms. The study used an objective infrared eye tracking device to measure gaze positions and found a significant correlation between the...