About The Study: This review synthesizes the latest policies and initiatives concerning representation in clinical research and provides a strategic framework to ensure scientific validity of clinical trials by operationalizing broad representation at all levels. A coordinated approach among stakeholders is needed to address the scientific value of trial representation of the intended use population.
Corresponding Author: To contact the corresponding author, Roxana Mehran, MD, email roxana.mehran@mountsinai.org .
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(doi:10.1001/jamacardio.2025.2421)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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JAMA Cardiology