Articles tagged with Population
A post hoc analysis of a cluster randomized clinical trial found that the Real-time Prescription Benefit Tool (RTPB) increased fill rates for high-cost medications, especially among patients from low-income communities. However, the tool's recommendations were only made for a small proportion of orders, limiting the study's applicability.
Active surveillance for favorable-risk prostate cancer increased significantly in the Veterans Affairs healthcare system, with high rates among low-risk and intermediate-risk patients. This trend suggests that many veterans are avoiding unnecessary treatment, but disparities in care persist.
A recent study found that individual demographic characteristics such as age, sex, and marital status are stronger predictors of being childfree than state context. The study analyzed data from over 20,000 US adults and found varying levels of childfree populations across states, with California having the highest percentage at 22%.
Non-US-born physicians, including US medical graduates and international medical graduates, account for nearly half of the US internal medicine workforce. They provide a disproportionate share of care for underserved patient populations.
The report highlights chronic underinvestment in Native American communities, with recent Trump administration cuts exacerbating the issue. The current lack of funding is particularly troubling, given increased investments during the Covid pandemic.
A randomized phase 3 study found that first-line osimertinib plus chemotherapy significantly improved median progression-free survival compared to osimertinib alone in patients with advanced non–small cell lung cancer (NSCLC) and concurrent EGFR and TP53 mutations. This study provides evidence for incorporating TP53-based molecular ris...
Residents agree that buying a home is harder today than for their parents, with 69% saying hard work alone is no longer sufficient. Generational differences emerge, with Gen Z prioritizing freedom and personal independence over homeownership and family.
Researchers found that disease prevention has reduced the incidence of heart attacks, strokes, and hip fractures, while cancer cases have increased. Improved diagnosis and treatment for cancer have led to better survival rates.
A cohort study revealed racial differences in sonographic evaluation, with a 76% completion rate and excellent cancer exclusion ability in Black women despite fibroids impairing endometrial visibility. Fibroid presence did not hinder cancer detection accuracy.
A new study from the University of Kansas reveals that everyday people often focus on punishment as a solution to gender-based violence rather than examining its causes. Commenters regularly called for imprisonment and stripping perpetrators of power and resources, with some even advocating for poverty as a form of punishment.
Artificial intelligence can exacerbate or mitigate inequities in correctional health systems. Designing AI for access, inclusion, and trust is crucial for ensuring health equity among incarcerated populations. The study outlines policy and implementation considerations necessary to address these concerns.
A new study documents how an Indonesian Indigenous community adapted their sacred Cidaku initiation ceremony to protect the endangered salmon-crested cockatoo. The ceremony now uses naturally moulted feathers collected from wildlife rescue centres, preserving spiritual integrity and ensuring species survival.
A new study published in BMJ Public Health found that people who live by the coast in midlife are more likely to have two or more diagnosed chronic conditions. The researchers attribute this to higher deprivation and selective migration patterns, where individuals with worse health tend to remain in or move to coastal areas.
Research highlights importance of cardiovascular care in breast cancer patients and survivors throughout life. Cardiovascular risk factors and interventions are essential to prevent disease progression and improve quality of life.
High LDL-C led to 3.6 million deaths and 90.7 million disability-adjusted life years in 2023, despite declining mortality rates. The absolute burden increased due to population growth and aging, with regional disparities emerging.
A cross-sectional study of 172 venture capital-backed maternal health startups identified significant gaps in pregnancy care delivery, particularly for low-income populations. The study found that while startups have the potential to facilitate innovation, few address health equity concerns.
Aging cells become more susceptible to ferroptosis due to elevated levels of acid ceramidase, a previously targeted therapeutic candidate. This vulnerability can be passed to neighboring cells, impacting overall tissue health. The discovery offers new hope for supporting healthy aging and treating age-related diseases.
A cohort study of Korean patients with lung cancer found that international screening guidelines excluded 64.6% of patients, many without smoking history. Ineligible patients had lower mortality risk than eligible patients, suggesting tailored approaches are necessary to enhance early detection.
The study found significant progress in reducing cancer mortality disparities for breast and uterine corpus cancers, but persistence in prostate cancer remains. The findings highlight the need for targeted interventions to accelerate progress in equitable cancer prevention and control.
A study found that measles-containing vaccines were administered to only 15% of children in this age group between 2015 and 2025. This proportion remained stable over time, but disparities in vaccine uptake existed among minoritized racial and ethnic groups.
A new study reveals that Amazonian communities use at least one-third of the region's known plant species, totaling 5,796 species. Climate change is expected to lead to a decline in biocultural heritage by 26% from 2060 to 2080, threatening Indigenous cultural identity and ecosystem services.
Researchers have identified high rates of overweight/obesity (82%) and hypertension (higher than statewide average) in Franklin Parish, with income levels linked to lower hypertension rates. Older residents are also more likely to have undiagnosed high cholesterol and diabetes.
The study found that primary care clinicians can make a significant impact on diabetes management by initiating continuous glucose monitoring, leading to improved glycemic control and reduced acute care utilization. This scalable strategy has the potential to improve diabetes outcomes in underserved populations.
A nationwide population-based study found that individuals with neovascular age-related macular degeneration had a modest but statistically significant increase in overall cancer risk. However, the increased risk was only observed for specific malignancies, including thyroid, kidney, and prostate cancers.
A cross-sectional study found that colorectal cancer screening participation increased after an organized population screening program, but socioeconomic disparities remained. Younger age groups, single households, and lower-income individuals still lag behind in screening uptake.
Hospitalized children with acute respiratory tract infections often have underlying chronic conditions that require intensive care. The study found that these patients are at a higher risk of severe disease and death. Understanding the epidemiologic profile of this population can help optimize outcomes for pediatric patients.
A study found that implementing earlier egg introduction guidelines resulted in measurable decreases in egg allergy cases. The updated guidelines, based on randomized trial evidence, may contribute to a reduction in food allergy prevalence when effectively implemented.
In an exploratory analysis, finerenone was found to slow kidney function decline, reduce albuminuria, and lower the risk of kidney failure or substantial loss of kidney function in patients with glomerular diseases. These findings suggest a crucial role for finerenone in preserving kidney function in this population.
A study by researchers at Science Tokyo found that non-structural disaster measures in Macau significantly improved coastal resilience and reduced storm-surge impacts. The city's emphasis on evacuation guidance, communication, monitoring systems, and public awareness helped build trust and reduce disaster impacts.
A national cohort study found that living in high-segregation neighborhoods was associated with lower likelihood of live donor liver transplant (LDLT) access. Candidates from high-segregation neighborhoods with larger racial and ethnic minority populations had a lower likelihood of LDLT compared to those from white populations.
A difference-in-differences analysis found that Georgia's Pathways to Coverage program worsened mental health among low-income adults. This suggests that work requirements may create barriers to coverage and care access, affecting population health and equity.
The study found that population-based pathogenic variant testing reveals different subsets of high-risk women than clinical risk factors and polygenic risk scores. This highlights the importance of incorporating PV testing into risk-based screening for breast cancer.
A population-based screening trial evaluating a cell-free DNA multicancer early detection test found modest increases in diagnostic delay rates for head and neck, lung, and upper gastrointestinal cancers. These findings suggest that future trials may need to consider system-level spillover effects on healthcare resources.
In a cross-sectional study of ambulatory visits, digital after visit summary engagement was found to increase but remained low, especially among unmarried males, non-English-speaking populations, and publicly insured populations. This inefficiency highlights the need to reevaluate postvisit communication in these groups.
A large cohort study found that antenatal opioid exposure was associated with impaired cerebral cortical folding in newborns. The extent of impairment differed based on the opioid type and presence of polysubstance exposure. Longitudinal assessments aim to inform early interventions for vulnerable populations.
Decades of research on UK birth cohorts suggest a 'generational health drift' where more recent generations experience poor health earlier in life, particularly obesity and mental ill health. This trend is driven by worsening social and environmental exposures rather than improvements in healthcare.
A new AI-powered cardiopulmonary resuscitation instructor has been developed to support bystanders during out-of-hospital cardiac arrests. The study suggests that this technology could be a scalable public health intervention to save lives.
A randomized clinical trial suggests psilocybin is safe and efficacious for treating cocaine use disorder. The study found psilocybin to be effective in reducing substance use and improving mental health outcomes.
A recent study reveals that individuals with higher education or income are more aware of and use AI tools, exacerbating social inequalities. The researchers recommend increasing engagement with AI-related topics through outreach campaigns, educational programs, and community workshops to reduce this new digital divide.
Orange County residents hold broadly positive but carefully qualified views on immigration, recognizing its benefits while drawing distinctions around enforcement. The UCI-OC Poll found that Orange County residents are pragmatic about immigration, supporting targeted enforcement against human trafficking and limiting immigration from u...
Researchers found that malaria significantly influenced habitat choice, pushing groups away from high-risk environments and separating populations. This led to the fragmentation of human societies, shaping their population structure for the past 74,000 years.
A new study from Florida Atlantic University challenges the narrative that rising temperatures will drive Americans away, finding that heat alone isn't driving large-scale out-migration. Instead, population shifts are shaped more by economic opportunity, housing affordability and local quality of life than climate conditions.
A nationwide study reveals that individuals with lower educational attainment are more likely to die from colorectal cancer at a younger age. The disparity in young-onset CRC mortality nearly doubled over the past three decades among those with 12 years or less education compared to those with 16 or more years of education.
Advances in high-throughput proteomics and artificial intelligence are transforming biomarker discovery, disease prediction, and drug development. Proteomic technologies enable comprehensive snapshots of physiological and pathological states, driving breakthroughs in early diagnosis and personalized treatments.
A notable minority of US youth and young adults, particularly those facing structural disadvantages and mental health distress, engage in intentional online searches for gun-related harm. Public health strategies combining digital interventions with structural reforms offer promise to reduce gun-related harm among vulnerable populations.
A major European study found that loneliness affects the memory of older adults, but does not speed up mental decline over time. Participants who reported high levels of loneliness performed worse on initial memory tests, but their ability to recall information declined at a similar rate as those with lower loneliness levels.
Extended low-dose apixaban effectively reduced symptomatic superficial vein thrombosis (SuVT) risk. Patients with enduring risk factors for SuVT benefited from this anticoagulation strategy.
Children with metabolically healthy obesity at treatment initiation have an increased risk of type 2 diabetes, hypertension, and dyslipidemia. Reduction in BMI z score is associated with reduced cardiometabolic risk, suggesting treatment should be recommended for these children as well.
A statewide cohort study found childhood mortality is significantly higher among children bereaved by parental drug overdose, homicide, and suicide. Parental homicide was associated with the highest risk of mortality in children, highlighting the need for research into potential explanations such as family restructuring and mental health.
A new study found that walking pace is a strong predictor of mortality risk, especially in people with existing health conditions. Combining walking pace with other physical measures improved mortality predictions, suggesting a simple and cost-effective way to identify high-risk individuals.
Research suggests significant heat-health risks observed among socioeconomically vulnerable populations. This study underscores the importance of developing targeted heat warning strategies to mitigate these risks and prevent emergency department visits among older adults.
A population-level cohort study of 20 low-mortality countries found that females aged 35-60 have higher cancer mortality rates than males, despite similar treatment and diagnostic pathways. The study highlights the need for targeted action to improve the prevention, early detection, and treatment of female reproductive cancers.
A nationwide cohort study found a significantly elevated incidence of out-of-hospital cardiac arrests on post-holiday weekdays, particularly among vulnerable populations after consecutive rest days. The study supports enhanced emergency preparedness and targeted public health messaging during holiday periods.
A large representative study found that 3 in 10 Indigenous adults meet criteria for healthy functioning, highlighting the importance of addressing structural barriers and promoting culturally meaningful pathways to wellness. Financial security, physical activity, and reduced chronic illness were key predictors of healthy functioning.
A study found insufficient sleep among US adolescents, with trends suggesting environmental and structural factors are driving the issue, rather than specific behaviors. The findings highlight the need for population-level interventions to address widespread sleep loss.
A population-based study reveals that rotator cuff abnormalities are common after age 40 and often represent normal age-related changes. The findings challenge the clinical value of routine imaging for atraumatic shoulder pain, questioning the need for regular scans in this demographic.
The study found increased requests for medication abortion among adolescents in states with gestational bans and parental consent requirements. Young adults also sought more medication abortion services post-Dobbs, with the highest demand in states with restrictive abortion laws.
A historical analysis of Surinamese slave registers found that young children who grew up without a mother were more likely to die, while the presence of grandmothers significantly increased their chances of survival. Family members played a crucial role in protecting children from harsh conditions.
A study found that women in the public service sector tend to report satisfaction with their work, but also struggle with suppressing negative emotions. The researchers surveyed over 120 women and discovered that most never felt ashamed or scared at work, but many reported hiding their true feelings due to job expectations.
Research highlights increased mortality risks among individuals with autism spectrum disorder, intellectual disability, or cerebral palsy compared to the general population. The study's findings can inform public health strategies to address health disparities and excess mortality associated with developmental disabilities.