Articles tagged with Population
This special issue of JAMA Network Open highlights scientific progress in combining social determinants and health outcomes to understand mechanisms underlying health disparities. The studies demonstrate the importance of interdisciplinary integration in transforming health disparities research.
α-Synuclein pathology in asymptomatic stages is linked to NBM atrophy, leading to attention/executive impairment. MRI signatures can detect this pathology in memory clinic populations.
A new study from the University of California, Berkeley reveals a significant increase in underweight and premature births among non-white women in the US after Trump's election. Black mothers had the largest increases, with about 3,783 fewer infants born underweight if Trump hadn't been elected.
A study reveals that sexual and gender minority adults in the US have a higher risk of developing epilepsy due to unique biological and psychosocial factors. The findings highlight the need for protected access to medical care for this population.
A nested case-control study found that completing fecal immunochemical tests lowers overall death risk from colorectal cancer, particularly in the left colon. The association was observed across racial and ethnic groups, supporting its use in population-based screening strategies.
A population-level study found no increase in neonatal and infant mortality rates during the initial COVID-19 pandemic period. However, social distancing measures were linked to higher preterm birth rates with a lag period.
A study of nearly half a million women found that endometriosis was associated with a higher risk of ovarian cancer. The risk was particularly elevated among women with ovarian endometriomas or deep infiltrating endometriosis, with a 19-fold increased risk for certain types of ovarian cancer.
A new study found that an electronic health record (EHR)-based nudge intervention significantly decreased low-value axillary surgery in older women with clinically node-negative, HR+/HER2− breast cancer. The user-friendly intervention could be beneficial for other practice settings or patient populations.
Research reveals that residents of America's wealthiest communities face higher economic losses from natural disasters and exposure to air pollution, despite having more assets. In contrast, low-income municipalities have higher suicide rates, homicide rates, and firearm fatalities, but lower access to health services.
Tirzepatide was associated with significantly greater weight loss than semaglutide in adults with overweight or obesity. Future studies are needed to explore differences in other outcomes.
Researchers found GLP-1 receptor agonists lower risks of certain obesity-associated cancers in patients with type 2 diabetes, suggesting potential benefits for cancer prevention in high-risk populations. The study provides preliminary evidence supporting further preclinical and clinical studies to prevent specific obesity-linked cancers.
A recent study published in JAMA Internal Medicine reveals that transgender and gender-diverse adults in the US experience over 2-fold increases in frequent mental distress and depression. The population also faces significant health inequities compared to cisgender counterparts.
Research by Osaka Metropolitan University suggests that converting vacant homes in old new towns into healthcare facilities can slow population decline. This urban transformation can enable older adults to remain in their communities, promoting healthy and connected living.
Generation X sees gains in leading cancers, but lower rates of lung and cervical cancers compared to previous generations. Cancer incidence could remain high for decades if current trends continue.
A 15-day course of nirmatrelvir-ritonavir did not demonstrate a significant improvement in select postacute sequelae of SARS-CoV-2 infection symptoms in vaccinated adults with prolonged symptom duration. Further studies are needed to determine the role of antivirals in PASC treatment.
A recent study published in JAMA Network Open found a positive association between heavy lifetime cannabis use and cardiovascular disease mortality among female participants. The study suggests that long-term cannabis use may have negative effects on mortality rates, highlighting the need for further research.
A study of over 24,000 people found that mixed social networks with diverse friends improve social cohesion and personal well-being. People with heterogeneous friend groups reported higher levels of social cohesion within their neighborhoods, closely associated with increased life satisfaction.
Research highlights varied associations between social isolation and mortality risk across demographic groups, including socioeconomic disparities. The study emphasizes the importance of considering sociodemographic heterogeneity in understanding the impact of social isolation on health outcomes.
Adult carriers of BAP1 tumor predisposition syndrome show a high incidence of onychopapillomas, a benign nail tumor. This finding suggests using these skin abnormalities to identify family members and patients with cancers associated with the syndrome.
Cardiovascular biomarkers strongly associated with cardiovascular events and mortality. Adding biomarkers to established risk factors improved heart failure and mortality prediction, but only slightly enhanced atherosclerotic disease risk prediction.
Black and Hispanic patients with atrial fibrillation were less likely to initiate direct oral anticoagulants at study onset, but these disparities narrowed over time. The study highlights the need to address unequal access to novel therapies for Black and Hispanic populations.
A cohort study found that individuals with a first colonoscopy with negative findings for colorectal cancer may benefit from longer screening intervals, potentially up to 15 years. This could lead to fewer unnecessary invasive examinations and improved patient outcomes.
A new study finds that initiating antihypertensive medication in older long-term care residents increases fracture risk, particularly among those with dementia. The study advises caution when prescribing antihypertensives to this vulnerable population.
A study of 322 participants found racial discrimination to predispose Black young adults to metabolic syndrome through sleep issues and chronic inflammation. This discovery could inform targeted prevention strategies to address existing health disparities in minority populations.
Research suggests that mentally active employees are less likely to experience cognitive decline and dementia-related issues. The study analyzed various interventions aimed at boosting mental performance, revealing promising results for those looking to reduce the risk of age-related brain decline.
The study reveals that smartphone-based cognitive assessments can provide reliable and valid results for diagnosing frontotemporal lobar degeneration. These findings suggest a scalable solution for remote evaluations, which may enhance early detection.
A cohort study of 64,000 Americans found that nearly 80% consumed excessive sodium, associated with 10-30% increase in cardiovascular disease mortality. Public health programs targeting reduced sodium intake may be beneficial for this underserved population.
A study of partners and adult children of stroke survivors found higher risks of mental health conditions and self-harm or suicide. The findings highlight the potential consequences of stroke on family members, particularly partners.
This study of 536 adults with chronic conditions found disparities in patient portal use, with sociodemographic groups and health literacy levels showing varying trends. The COVID-19 pandemic led to an increase in portal use, while a brief validated health literacy measure may help identify patients who need further support.
The study reveals a significant prevalence of refractive error in African American adults, affecting their quality of life and work productivity. Providing universal vision care coverage can reduce this burden by over two-thirds, improving lives and increasing economic opportunities.
Weight loss treatments such as nutrition counseling and bariatric surgery increased the patient-level probability of achieving significant weight loss. Current treatment utilization rates are insufficient to impact the population level, highlighting a need for improved access.
A systematic review and meta-analysis of 104 studies with 341,000 participants found that physical activity was associated with better late-life cognition, although the association was weak. The findings suggest that even a weak link between physical activity and cognitive decline is still important from a population health perspective.
A study of 87,000 women found a higher level of maternal autistic traits associated with increased risk of adverse birth outcomes, including very preterm birth. The researchers emphasize the need for tailored and timely antenatal care support for women with high levels of autistic traits.
Adult cancer survivors are at higher risk for substance use disorders (SUD), especially those with certain types of cancer; the study suggests integrated care could benefit these patients. The research highlights the need to address comorbid SUD in cancer populations with high SUD prevalence, prioritizing high-risk cancers.
A study in the JAMA Network Open found that Hispanic and American Indian individuals with breast, colorectal, lung, and prostate cancer were undercaptured in the National Cancer Database, but representation improved over time. Further investigation is needed to understand where these populations seek cancer care.
A NSF-funded project, MABLE, is developing a digital app using crowdsensing, AI, and robotics to empower individuals with responsive maps and turn-by-turn instructions. The app aims to improve accessibility and navigation for persons with visual or mobility impairments, such as those with low vision and wheelchair users.
A large study found that sleep disturbances in preschool-aged children are strongly associated with both resolved and new cases of emotional and behavioral difficulties. Routine screening and treatment of sleep issues may help improve psychosocial well-being in this population.
A study of 4,819 women with benign breast disease found an increased risk of breast cancer compared to the general population. The study's findings suggest that pathologic classifications could improve breast cancer risk stratification.
This study reveals racial and ethnic differences in hospice use, with Hispanic and non-Hispanic Black individuals having lower odds of receiving hospice care. Hispanic individuals had the highest odds of a short hospice stay, highlighting potential barriers to access and acceptance among low-income populations.
A simulation study suggests that a soft drink tax in Germany would reduce sugar consumption and illness rates, including type 2 diabetes, resulting in significant financial savings. The estimated economic benefits of introducing such a tax range from 9.5 billion to 16 billion euros over the next two decades.
A study by Dr Lixin Ren found that extracurricular activities have a limited impact on math skills in preschool children, with effects dependent on behavioral regulation and approaches to learning. For children with poor self-regulation skills, structured activities can improve early math skills.
The study found co-administration of the Pfizer-BioNTech COVID-19 vaccine with the seasonal influenza vaccine to be effective in preventing COVID-19 and flu-related outcomes. This may improve vaccination uptake for both vaccines.
Maintenance immunosuppressive drugs linked to increased COVID-19 hospitalization risk in solid organ transplant patients. Clinicians treating transplant recipients should consider these findings for epidemic-related decisions.
A study of 185 women found that high neighborhood deprivation was associated with changes in DNA methylation and gene expression in Black women with breast cancer. This suggests a potential link between environmental factors and biological susceptibility to chronic diseases.
A study found that Acinetobacter baumannii and Candida auris were common among patients receiving mechanical ventilation, particularly in long-term care facilities. These pathogens pose a significant risk to this vulnerable population, highlighting the need for targeted surveillance and prevention efforts.
A study of 4,070 insured adults with diabetes found persistent disparities in poor glycemic control, even after adjusting for social, healthcare, and behavioral factors. The research highlights the need for further investigation into the barriers contributing to these disparities.
A post hoc analysis of 10,678 participants with atherosclerotic cardiovascular disease found no significant difference in heart attack, stroke, or death risk between enteric-coated and uncoated aspirin. Enteric-coated aspirin may offer reduced bleeding risk, but more research is needed to confirm its benefits.
A study published in JAMA Network Open found a persistent increase in psychotropic medication dispensation among children and adolescents with type 1 diabetes. The findings highlight the need for integrated pediatric diabetes care and mental health services to detect psychological needs early on.
A significant burden of cardiovascular disease and cardiometabolic risk factors has been identified among 220,000 American Indian and Alaska Native patients with Medicare insurance. The study emphasizes the critical need for future efforts to prioritize cardiovascular health in this population.
A study of 44,000 low-income adults found that providing public health insurance to immigrants has a lower direct cost than for US-born individuals. Upon coverage, immigrants' healthcare utilization remains relatively modest, contradicting the assumption that offering insurance would significantly impact healthcare expenses.
A study of 24,000 hospitalized COVID-19 patients found that pulse oximetry led to delayed treatment and higher readmission rates, with racial disparities observed among black patients. The study highlights the importance of accurate oxygen saturation monitoring in preventing these outcomes.
A new DNA study reveals that the intermingling of hunter-gatherer groups in Europe was strongly linked to geography, with certain groups remaining isolated for thousands of years. The research adds detail to the puzzle of European Stone Age history.
Consistent disparities among marginalized populations are more likely to experience unexplained queue jumps and hallway placement. Standardizing triage processes can help mitigate conscious and unconscious biases in emergency departments.
A study of 22,000 adults found that small amounts of vigorous intermittent lifestyle physical activity were associated with a lower incident cancer risk. This finding suggests that daily vigorous intermittent lifestyle physical activity may be a promising intervention for cancer prevention in populations unable or unmotivated to exercise.
A recent study found that travel-related barriers significantly impact access to healthcare, particularly for marginalized communities. The research emphasizes the need to remove these barriers to achieve health equity.
Smoke-free legislation associated with significant reductions in morbidity and mortality related to cardiovascular disease and respiratory system disease. Accelerating the implementation of smoke-free laws is crucial for protecting populations against smoking-related harm.
The study highlights the increasing global burden of childhood diabetes, with rising deaths and disability-adjusted life-years. Improved understanding of diabetes epidemiology in children is crucial for prevention and control efforts.
Medical evacuation by train in a war zone is possible and can transport more severely ill or injured individuals due to intensive care capacity on board. The target population should not be limited to trauma patients only.
Head and neck squamous cell carcinoma patients face substantial burden of uncontrolled cardiovascular risk factors, leading to increased risk of stroke and heart attack. Modifiable CV risk factor control is crucial in reducing the risk of adverse cardiovascular events and death among these patients.
A peer support group intervention has been shown to be feasible and acceptable among undocumented Latinx immigrants with kidney failure. The study found that the intervention built camaraderie and provided emotional support, which is particularly important for socially marginalized uninsured populations.