The CoDICE instrument will measure energized interstellar and solar particles to better understand the boundary of the heliosphere. The instrument will also characterize solar wind ions and the mass and composition of highly energized solar particles associated with flares and coronal mass ejections.
A materials science team has cracked the challenge of lead-free antiferroelectric design by co-doping sodium niobate with variable-valence elements. The researchers achieved a reversible field-induced phase transition and an ultrahigh electro-strain, making it ideal for power-storage capacitors and precision actuators.
A study reveals that oral lysozyme can restore a healthy gut balance and reverse signs of vascular aging in older adults. The research identifies the PI3K–Akt signaling pathway as a key mediator, suggesting new lines of research into metabolites and microbial strains for vascular health.
A UBC Okanagan research team has developed TrajReducer, an AI system that accurately predicts vessel destinations by analyzing ship trajectories and patterns. This technology can help Canadian ports adapt quickly to global supply chain disruptions and improve operational efficiency.
The tumor microenvironment in osteosarcoma plays a critical role in disease progression and treatment resistance. Targeting the interplay between cancer cells, immune components, stromal elements, and extracellular matrix is crucial for developing effective treatments.
Researchers from Binghamton University confirm the long-held 'urban myth' that saltwater dries out skin, increasing tissue stiffness and stress. A simple solution to alleviate tightness is taking a shower after coming out of the ocean.
Scientists from TU Delft have demonstrated quantum spin currents in graphene without external magnetic fields, a crucial step towards spintronics and next-generation technologies. These robust spintronic devices promise advancements in quantum computing and memory devices.
Researchers identified 'uncommitted' cells in neuroblastoma tumors that exhibit weaker cancer development, potentially leading to favorable outcomes for patients. These cells may help identify early diagnostic markers and novel therapeutic targets.
The team developed a novel composite material featuring platinum nanoparticles anchored on three-dimensional Na-Ti3C2Tx structures for highly efficient dopamine detection. The composite's larger active surface area enhances the stability of the structure and improves electron transfer, leading to excellent sensitivity and performance.
Recent findings reveal TET1's dual role in disease progression, inhibiting malignant cell growth in certain cancers while driving oncogenic pathways in others. Abnormal TET1 activity disrupts epigenetic mechanisms, contributing to neurological disorders, metabolic diseases, and autoimmune conditions.
Researchers unveil a simple yet effective tool to track Spartina alterniflora, an aggressive invasive plant species threatening coastal wetlands. The new Spartina alterniflora Index (SAI) offers precise, large-scale mapping of the species using freely accessible Sentinel-2 imagery.
A study found that fish face a trade-off between tooth size and jaw mobility, restricting their ability to catch fast-swimming prey. Fish with larger teeth use rapid bursts of swimming to close in on prey, while those with extendible jaws rely on suction forces.
A study by researchers at the University of Gothenburg found that newborn babies and patients with Alzheimer's disease share elevated levels of phosphorylated tau, specifically p-tau217. In newborns, this protein reflects a healthy mechanism for brain development, while in Alzheimer's patients, it indicates disease progression.
Researchers at DTU developed a new electronic material that behaves like human skin, offering self-healing and adaptive properties. The material can stretch up to six times its original length, regulate heat, and detect environmental factors, making it suitable for wearable devices, soft robotics, and healthcare applications.
Trdn-as exacerbates diabetic cardiomyopathy by upregulating calsequestrin 2 via m6A modification. Elevated Casq2 causes mitochondrial damage and cardiac dysfunction.
A study by researchers from the University of Reading predicts that over 500 bird species will face extinction within the next century. The study highlights the importance of targeted conservation measures, including breeding programs and habitat restoration, to preserve global bird diversity.
A newly developed electrochromic harvester can toggle between solar heating and radiative cooling, providing programmable thermal regulation without sustained power input. This technology has the potential to transform HVAC strategies across industries, offering self-regulating thermal envelopes and reducing energy consumption.
A new study predicts cognitive abilities from brain scans by integrating multiple MRI modalities through a technique called stacking. The method achieves substantial predictive accuracy and improved test-retest reliability, suggesting a more reliable neural marker of cognitive function.
Scientists at Rice University develop a new method to align boron nitride nanotubes (BNNTs) in water using a common surfactant, creating ordered liquid crystalline phases. The discovery enables the production of transparent, robust films ideal for thermal management and structural reinforcement applications.
The University of Texas MD Anderson Cancer Center has earned its sixth Magnet designation and first Magnet with Distinction rating, reflecting outstanding patient care, leadership, innovation, and expertise among its 5,300 nurses. This achievement validates the vital role of nursing in cancer care.
The BfR Summer Academy, an international event, brings together 23 participants from 17 countries to discuss food safety and risk assessment. Participants learn about the legal and institutional background of food safety in Germany and Europe.
Research published in Occupational & Environmental Medicine found a strong association between working in person-contact roles and an increased risk of developing type 2 diabetes. High levels of emotional demands and confrontation were particularly linked to a higher risk, especially among those with low social support at work.
A new study by IMT School for Advanced Studies Lucca analyzed the effects of the 2016 EU-Turkey Statement on irregular migration and mortality in the Mediterranean. The research found that the deal led to a surge in lives lost at sea, particularly on the Central Mediterranean route, with nearly double the death rate after the agreement.
Researchers uncover the crucial role of dermal T cell immunity in regulating hair follicle regeneration and addressing immune-mediated alopecia. The intricate relationship between T cells and hair follicle regeneration is driven by key regulatory signaling pathways that dictate the activity of epithelial stem cells.
A research team analyzed YouTube videos of sleeping cats to find that two thirds sleep on their left side. This bias is thought to be an evolutionary strategy, favoring the use of the right hemisphere of the brain for spatial awareness and threat processing after waking.
A George Mason researcher is leading a national initiative to equip researchers with tools and training to engage effectively in policymaking. The project aims to establish 'communicating science for policy' as a key dimension of civic science.
A study by the University of Münster found that families cultivate a religious self-image and engage in joint practices are crucial for transmitting religion. The most important role is played by mothers, while regular communication with a religious figure also plays a key role.
Lysine lactylation is a novel post-translational modification connecting cellular metabolism with gene expression and protein function. Non-histone Kla has diverse roles in inflammation, DNA repair, cancer metabolism, and immune signaling.
The WUI-NITY simulator, developed by a global collaboration of researchers, visualises bushfire spread and people movement to calculate evacuation times. It has been validated in large-scale community evacuation drills and is freely available online for use by authorities and researchers.
A new poll reveals significant variation in older adults' preparations to age in place, with 46% having taken steps to make their home more age-friendly. However, differences persist based on health, disability, and home ownership status, highlighting opportunities for policymakers and families.
Researchers have discovered two signaling molecules that can reprogram ant duties, mirroring gene-expression patterns found in eusocial naked mole-rats. These findings suggest a convergent molecular mechanism dating back hundreds of millions of years, hinting at the evolutionary depth of social behavior.
Researchers at The University of Tokyo have developed a 'molecular flask' that modulates chemical reactions, allowing for the creation of specialized polymers in extremely small spaces. This breakthrough technology enables the production of complex materials with various applications, including optoelectronics and medicine.
Scientists at UNIGE have identified MLF2 and RBM15 as key proteins regulating chromatin remodelling, which can go awry leading to cancers and neurological disorders. These two proteins could become promising therapeutic targets for diseases linked to disrupted chromatin remodelling.
The new NCCN Guidelines Navigator tool offers an interactive platform for accessing evidence-based guidelines, facilitating easier searching and navigation. The initiative aims to improve patient care and outcomes by providing healthcare professionals with up-to-date recommendations.
Ribosome biogenesis is crucial for liver regeneration, hepatitis C virus infection, nonalcoholic fatty liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma. Targeted therapies targeting ribosome biogenesis may offer new treatment options for chronic liver diseases and liver cancer.
Despite decades of progress, global immunization targets are unlikely to be met due to stagnant childhood vaccination rates and inequality. The COVID-19 pandemic has further exacerbated the issue, with widespread vaccine misinformation and hesitancy contributing to faltering immunization progress.
A large UK study found a significant association between autoimmune diseases and persistent mental health issues, with higher risks in women. Chronic exposure to systemic inflammation may explain the associations, researchers suggest.
Jean-Luc C. Urbain has been named president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), aiming to integrate radiopharmaceutical theranostics into clinical practice. As president, he plans to prioritize research, education, and patient safety to benefit patients worldwide.
The review highlights the significance of fusion genes across various cancers, including hematological malignancies, lung cancer, thyroid cancer, and prostate cancer. Fusion genes disrupt normal cellular processes, leading to uncontrolled proliferation and metastatic potential.
ADC189 demonstrates potent antiviral activity across multiple strains, including oseltamivir-resistant variants, and robust efficacy in murine models. Phase I data reveal a favorable pharmacokinetic profile, prolonged half-life, and no food-related absorption interference.
Researchers have discovered two new viruses closely related to Nipah and Hendra viruses, as well as other microorganisms, in bats from Yunnan province. The study highlights the need for comprehensive microbial analyses of previously understudied organs to better assess spillover risks.
Researchers found whales and dolphins, including an endangered sperm whale, in the Clarion Clipperton Zone, a vast area of deep ocean and seamounts. Chronic exposure to mining noise could disrupt key behaviors, leading to cascading ecological consequences.
A recent study predicts the origin of Chondria tumulosa, a cryptogenic red macroalga taking over Hawaiian coral reef ecosystems. The research provides tools for resource managers to develop effective management strategies.
A new UVA Health study finds that stocking two twin packs of epinephrine autoinjectors and having campers leave their own at home is the most cost-effective strategy for residential camps. This approach comes with an estimated overall cost of $4.33 per camper.
Researchers developed an AI tool called AAnet to characterize cancer cell diversity, identifying five distinct cell groups with different gene expression profiles. This could lead to more targeted therapies and improved patient outcomes.
The collaboration aims to bridge academia and industry through joint research projects, academic exchange, and hands-on training for students and faculty. The partnership also opens career opportunities for UAEU graduates at Insilico, fostering local talent and supporting the expansion of the UAE's biotechnology sector.
A new study found that providing households with simple, low-cost information about their drinking water quality increased the use of safe water practices by 26-48% in areas where many families rely on unsafe supplies. This approach has the potential to save lives at a lower cost than other public health programs.
Top ten errors identified by Dr Dan Green include incorrect causal language, poorly formatted abstracts, and statistical analysis sections with inaccurate or incomplete details. The article provides recommendations for researchers to avoid these common mistakes and advance a transparent and reproducible research world.
An AI model developed by Ehsan Ghane at the University of Gothenburg can predict the durability and strength of woven composite materials, reducing development time. The model integrates material laws to make extrapolations outside training data, enabling better understanding of material behavior.
Scientists at KIT have produced an MOF in thin-film form that exhibits metallic conductivity, enabling new possibilities for electronic components and applications. The breakthrough was achieved using a self-driving laboratory and precise control over crystallinity and domain size.
Researchers in China designed and developed a high-performance double-spoke superconducting cavity with improved electromagnetic and mechanical optimizations. The cryomodule employs carbon fiber tie rods to reduce heat leakage and enhance manufacturability. An optimized cryogenic cooling protocol was also developed to maximize Q-value ...
The USPSTF recommends screening for intimate partner violence in women of reproductive age. Screening for caregiver abuse is not recommended due to insufficient evidence. Abuse can result in significant injury and long-term health consequences.
Researchers analyzed fossil and living animal bones to reconstruct the path to upright posture, finding bursts of innovation and adaptive radiations. The study suggests that fully parasagittal postures evolved relatively late in mammalian history, contradicting previous theories.
A recent study published in The American Journal of Pathology has discovered that ADAM10 regulates abnormal blood vessel growth in the retina, which can cause vision loss or impairment. The findings suggest that targeting ADAM10 or its downstream effectors, such as Ephrin B2, may offer novel strategies for managing or preventing retina...
A research team fabricated high-performance flexible micro-supercapacitors using a novel MXene-hydroxylated nanocellulose-carbon nanotube composite ink system. The devices demonstrated outstanding performance stability and customizable energy storage modules for wearable microelectronic systems.
Heather Jacene, MD, has been elected as the new president-elect of SNMMI, with a focus on strengthening the organization and promoting nuclear medicine. She aims to create opportunities for member participation and multidisciplinary collaborations, while raising awareness of nuclear medicine's value to clinical colleagues and patients.
A novel PET imaging approach can accurately detect and monitor Mycobacteroides abscessus lung infections. The technique uses 11C-PABA PET to differentiate between bacterial infection and inflammatory diseases.
The Association for Molecular Pathology publishes guidelines for detecting homologous recombination deficiency (HRD) in cancer. The report includes recommendations for clinical laboratories, addressing technical aspects of genomic instability and HRD analysis.
A study on Americans' behavior after the COVID-19 shutdowns found that people often delay returning to lost pleasures. Participants reported waiting longer to satisfy their first time back, indicating a desire for a special experience.
A University of Vienna study finds that fructose increases monocyte sensitivity to bacterial toxins, leading to enhanced inflammation. Short-term high fructose consumption can significantly impact the immune system in healthy adults.