Researchers develop operando magnetism platform to track electronic/magnetic structure evolution in Li-rich Mn-based materials. They uncover dynamic relationships between magnetization, electronic structure, and oxygen interactions.
A research team creates a novel aerosol-based emulsion system that enables self-assembly of asymmetric nanostructures without relying on stabilizing chemicals. This breakthrough has shown promise for real-world applications in fields like biomedicine and optical devices.
Researchers at UCSF found clinically significant improvements in mood, cognition, and motor function after psilocybin therapy for patients with mild to moderate Parkinson's disease. The study suggests that psilocybin could provide relief from multiple symptoms of the disease by reducing inflammation and promoting neuroplasticity.
This study investigates the vibrational spectroscopy of lead-free potassium sodium niobate and related perovskite ferroelectrics. Raman and Brillouin scattering spectroscopies are used to analyze the lattice dynamical properties, phase transitions, and physical properties of KNN single crystals and solid solutions.
The partnership aims to leverage AI in developing innovative digital therapeutic solutions to prevent diseases in children. Researchers will use gamified digital therapy solutions on mobile devices to encourage healthier behaviors.
Researchers developed a new method to predict the effectiveness of mangroves in protecting coastlines against extreme weather events. The HU method uses wave non-linearity and can calculate wave height attenuation with ease, saving billions of dollars worldwide.
A new study published in Proceedings of the Royal Society B: Biological Sciences sheds light on how a 252-66 million-year-old 'marine revolution' influenced foraminifera diversity and survival. The study found that calcareous forams flourished after the MMR, becoming dominant types living today.
A centralized and accessible database aims to integrate molecular simulation data, ensuring findability, accessibility, interoperability, and reusability. This will amplify the impact of these data and avoid duplication.
Andrew Yang will study proteins crossing the blood-brain barrier and their role in brain health, seeking new therapies for neurological diseases. The 2025 Searle Scholar's research could lead to a better understanding of age-related disorders.
A new combination therapy using siRNA and a proprietary ferritin nanoparticle-preS1 vaccine has shown to achieve stable functional cure in mice with chronic hepatitis B. The treatment resulted in sustained HBsAg clearance, efficient seroconversion, and high levels of serum HBV DNA clearance.
Researchers have developed a new class of x-ray detectors that can detect extremely weak X-ray signals, reducing the radiation dose required for imaging. The enhanced CsPbBr3 detectors employ innovative cooling and defect-passivation strategies to boost sensitivity and suppress noise.
Researchers developed a novel 'torsion unipolar barrier heterojunction' device for wide-spectrum, high-precision polarization detection. The device features bipolar photocurrent behavior at zero bias and eliminates the need for auxiliary polarizers.
Researchers have discovered a novel way to achieve spin-valve effects using kagome quantum magnets, eliminating the need for complex fabrication techniques. The breakthrough enables giant magnetoresistance effects exceeding 160% in low-power-consumption devices.
Research found seasonal variations in genes responsible for drug metabolism, including CYP2D6 and CYP2C19, which affect a quarter of common medications. Alcohol tolerance also varies by season, with mice recovering more quickly from winter conditions.
A new technology, in the form of a wristband with colored buttons, allows children to communicate their play intentions and facilitate inclusive play. Researchers hope this innovation will enable both neurodivergent and neurotypical children to connect and play together.
Researchers found it takes parents about a year to attune to their child's attitudes towards school once they start education. By Year 1, parental perceptions of how a child feels about school most closely match responses given by the child when they were in Reception class a year earlier.
A long-term study published in BMJ Quality & Safety found that employing too few permanent nurses on hospital wards is linked to longer inpatient stays, readmissions, patient deaths, and ultimately costs more. Redressing the balance saves around £5000 for each year of healthy life gained, but not if temporary agency staff are used.
Researchers at Amsterdam UMC have developed a new diagnostic test that measures CRP protein in cerebrospinal fluid to quickly diagnose bacterial meningitis. The test has been shown to be very reliable and can start treatment within half an hour of diagnosis.
A study by scientists at the Smithsonian Tropical Research Institute found that juvenile fringe-lipped bats do not initially differentiate between palatable and unpalatable frogs and toads, but learn to identify toxic species through experience. As they mature, adult bats respond more strongly to palatable prey.
A groundbreaking international study found that spruce trees not only respond to solar eclipses but actively anticipate them by synchronizing their bioelectrical signals. Older trees exhibit a more pronounced early response, suggesting they retain environmental memory to inform younger trees of impending events.
Regular exercise can reduce side effects of cancer treatment, such as heart damage, nerve damage, and brain fog. It also improves psychological wellbeing, sleep quality, and overall quality of life in people with cancer.
A new study suggests that higher cigarette taxes can significantly improve childhood survival rates, particularly among the poorest children. The research found that increasing tax on cigarettes could narrow the socioeconomic gap in child mortality rates and save over 280,000 lives annually.
Mathematical modeling research from University of Utah Health suggests that treating moderate cases with antibiotics could limit the spread of cholera and reduce the likelihood of antibiotic resistance. In areas where cholera spreads slowly, aggressive antibiotic use may even stop outbreaks entirely.
A research team discovered fossilized teeth and vertebrae in the Dominican Republic, confirming that large, terrestrial predators like sebecids once inhabited the Caribbean. This finding supports the GAARlandia hypothesis, suggesting temporary land bridges allowed animals to travel between South America and the Caribbean.
A national study by Rutgers researchers found that nearly two-thirds of US adults have experienced some form of in-person gun violence, with Black and Hispanic adults more likely to be exposed. The study also revealed significant racial disparities in media-based exposure, with Black adults reporting the highest levels of exposure.
A new analysis of existing studies found that pedestrians and cyclists hit by SUVs or light trucks are more likely to suffer fatal injuries. The likelihood is higher among children, with a child hit by an SUV/LTV being 82% more likely to be killed than a child hit by a passenger car.
A new study found that pregnancy-related glycoproteins (PSGs) are strongly associated with poorer outcomes in female lung cancer patients. The analysis suggests targeting these genes may improve survival in female patients with lung cancer, and the researchers plan to pursue further investigation into their role.
Researchers at Mayo Clinic developed AI-ECG tools that can detect heart muscle weakness in women of childbearing age, allowing for earlier identification and management. The tools demonstrated high diagnostic performance, with an area under the curve of .94 for AI-ECG and .98 for AI digital stethoscope.
Cassandra Pierre, a BU researcher, has received the Bayard Rustin Award for Courage for her work on low-cost interventions to prevent infections in vulnerable populations. Her clinical interests include HIV management in pregnant women and subpopulations.
The review highlights the limitations of existing dengue vaccines, such as CYD-TDV and TAK-003, and the urgent need for more effective vaccines to protect millions of people. The Butantan-DV vaccine has shown promise with its single-dose regimen, but its efficacy against DENV-3 and DENV-4 is still unclear.
A new study reveals emerging cases of babesiosis in the Mid-Atlantic region, documenting human cases and detecting Babesia microti in local tick populations. The research highlights the growing public health threat posed by this tick-borne disease, emphasizing the need for increased surveillance, public awareness, and preventive measures.
A new study reveals that nearly 75% of ecology and evolution journals do not require authors to consider accessibility in manuscript submissions. The research team recommends adopting Universal Design principles, developing comprehensive guidelines, and fostering a culture of inclusivity.
Researchers have developed an algorithm to infer the structure of hypergraphs using only observed dynamics, allowing for the analysis of complex systems without prior knowledge. The approach was tested on EEG data from over 100 human subjects and accurately captured higher-order interactions in the brain.
MIT researchers have developed a way to produce large amounts of silk microneedles to deliver agrochemicals and nutrients to plants, showing promising results in treating chlorosis and adding vitamin B12 to tomato plants. The technology has the potential to serve as a new kind of plant interface for real-time health monitoring and biof...
The framework utilizes consortium blockchain architecture for immutable records, minimizing data falsification and cyberattacks. AI-driven tools ensure objective data collection and analysis, reducing human bias.
A new study from York University finds that age and previous sports experience are more significant factors in cognitive-motor integration than a history of multiple concussions. Researchers tested participants with a history of concussion on complex eye-hand coordination tasks, revealing neuroprotective benefits from sports experience.
A UCLA study found that nearly one-quarter of e-scooter-related injuries involved substance-impaired riders, who experienced almost double the risk of traumatic brain injuries compared to non-impaired patients. The study also highlights increased hospital costs for these patients, averaging $4,600 per case.
The NIH's new initiative prioritizes innovative human-centered methods like organoids, tissue chips, and real-world data analyses. This shift aims to replace animal use in medical research, reducing high failure rates in the drug development pipeline and promoting more ethical science.
Researchers propose a novel approach to reduce carbon emissions in cement manufacturing by leveraging iron naturally present in cement raw materials. The method enables the co-thermal conversion of CaCO₃ with CH₄ under a methane atmosphere, resulting in high-value syngas as a byproduct and significantly reducing carbon footprint.
Researchers at the University of Illinois found that piglets fed ad libitum gained more weight but had comparable soft tissue composition to those on prescribed feeding schedules. The study also tracked insulin concentration and behavior, revealing that ad libitum pigs may be growing faster due to differences in insulin production.
The American Heart Association backs Arkansas' effort to prohibit sugary beverage sales in SNAP, citing a need for reduced sugar intake. The organization has opposed Big Soda's efforts to block such measures.
Researchers at Texas A">&M found that dogs with meningiomas live longer with radiation therapy than surgery. Radiation nearly doubles average survival time in dogs with brain tumors, while surgery had an average of about 10 months.
Scientists have discovered a novel immune signaling pathway in bacteria that turns viral infection machinery against the virus, potentially informing future biotech tools and phage therapy. This discovery reveals an ancient defense strategy that could help fight superbugs.
A new study suggests habitual coffee consumption of 4-6 cups per day is associated with reduced risk of frailty. The research highlights the possible beneficial association between daily coffee consumption and reduced risk of frailty in later life.
Researchers developed an advanced detector system combining silicon and germanium detectors for high-efficiency charged-particle decay studies. The system achieved precise tracking of decay processes and efficient discrimination between particles, showcasing its potential for studying exotic nuclear structures.
Despite slight increase in prescriptions between 2021 and 2024, only 3% of eligible patients received a prescription. Disparities were found based on race, ethnicity, social vulnerability, and urbanicity, with small but significant differences compared to overall underutilization.
The American Heart Association has awarded $1M to research the link between cardiovascular risk reduction and GLP-1 use. The studies aim to identify predictors of cardiovascular risk reduction among individuals with obesity and cardiovascular disease taking GLP-1 medications, enabling more precise and effective care.
BiaPy breaks down the barrier to AI-based image analysis in biomedicine, allowing more scientists and healthcare professionals to harness its potential. The tool offers various types of analysis, including cell identification, element counting, and improving image quality, on both two-dimensional and three-dimensional images.
Researchers have developed three-dimensional spheroid cultures that better replicate cell-cell interactions and nutrient gradients, leading to a greater understanding of tumour tissue behaviour and drug responses. The study highlights the importance of mimicking tumour architecture in testing cancer therapies.
Researchers have developed novel methods for aerobic oxidation of organic compounds using molecular oxygen or air as green oxidants. Photocatalysis, electrocatalysis, and photoelectrocatalysis technologies offer new insights for sustainable chemical synthesis and development.
Researchers at UC San Diego develop novel approach to extract essential information from quantum systems, outperforming traditional methods in accurately predicting diverse quantum state properties. Experimental validation demonstrates the effectiveness of this technique in characterizing quantum states despite realistic noise.
A new study explores the future of EV ultrafast charging stations in China, finding that increased power capacity does not necessarily double station loads. The researchers propose two generalized solutions: energy storage and dynamic waiting strategies, which can effectively decrease peak loads and satisfy surging demands.
A recent study reveals that a specific genetic variation affects the adherence of an anaerobic bacterium to tumor cells, promoting colorectal cancer progression. The study highlights the complex dynamics between host genetics and intratumoral microbiota in CRC progression.
Researchers create silk iron microparticles that can be guided using a magnet to deliver drugs and treatments precisely to sites in the body. The development has potential applications in regenerative medicine, cancer therapies, and cardiovascular disease treatment.
A cohort study found maternal hypertension and preeclampsia independently associated with cognitive and language development delays in preterm infants. Recognizing hypertensive disorders of pregnancy is crucial for targeted risk management strategies.
A study by Emory University researchers has found that spiritual health practitioners' personal experiences with psychedelics drive their careers in the emerging field of psychedelic-assisted therapy. The study introduced a novel training approach, emphasizing self-literacy and reflective learning to balance personal experience with cl...
A study by Helmholtz Munich researchers found that GIPR agonism and antagonism decrease body weight and food intake via different mechanisms. GIPR agonists use GABAergic neurons to exert their effect, while antagonists rely on the GLP-1 receptor signal.
Researchers have discovered a new shape for energy storage using cone and disc carbon structures, which can store large ions like sodium and potassium efficiently. The discovery could lead to more affordable and sustainable battery technologies, reducing reliance on lithium.
Researchers developed a new computational method, KMAP, to explore DNA sequence patterns and reveal regulatory element behavior. The study found an uncharacterized DNA motif linked to cancer biology and identified distinct repair pathways for CRISPR-Cas9 editing.
The MyoStep project represents a significant advancement in pediatric mobility aids for children with cerebral palsy, addressing motor impairments that restrict participation in physical activities. The soft power suit provides a lightweight, discreet solution tailored to fit seamlessly into the lives of children and their families.
The DeCrises project explores how governance systems can adapt to overlapping disruptions and ensure equitable responses to societal challenges. It aims to generate actionable insights into citizen engagement, regional social innovation, and governance.
A research group led by Francesco Greco transformed marker ink into a graphene-based electrical circuit using a laser beam, creating a new frontier in electronics. The innovation uses simple and low-cost materials to generate innovative applications on any surface.
A recent study published in JAMA Network Open found that robotic cholecystectomy is associated with a higher risk of bile duct injury compared to the conventional laparoscopic approach. The study, led by Dr. Cody Mullens, analyzed Medicare data and found that bile duct injuries were approximately three times more common in robotic chol...
Despite increased rates of immediate breast reconstruction (IBR) since the Affordable Care Act (ACA) implementation, racial disparities in IBR have persisted. Hispanic women are more likely to undergo post-mastectomy breast reconstruction compared to non-Hispanic counterparts.
Dr. Jeff Williamson, an internationally recognized geriatrician and clinical trialist, will explore the impact of aging research on improving outcomes for all of us as we age. His work focuses on integrating aging-focused perspectives into clinical trials to ensure that care is aligned with the needs of an aging population.
New research highlights the critical role of teacher preparedness in addressing sexism in schools. The study found that knowledge, comfort levels, and belief in 'sexism socialisation' positively predict teachers' intentions to teach about sexism. Younger teachers also showed a greater inclination to address sexism.
The ROME trial found that patients with concordant biopsy findings experienced improved survival outcomes when receiving tailored therapy based on genomic alterations detected in both tissue and liquid biopsies. This approach led to better overall survival, progression-free survival, and objective response rates compared to standard-of...
A study found that journalism engagement training reduced the prevalence of 'horse race' stories and boosted more substantive, community-oriented content. The training program, Democracy SOS, worked with journalists and news outlets across the country to promote solutions-focused coverage and increase transparency.
A study by the University of Eastern Finland reveals that traffic-derived ultrafine particles influence gene regulation in human olfactory mucosa cells, particularly affecting the PI3K/AKT signaling pathway. The findings suggest a potential link between air pollution and neurodegenerative diseases.
Researchers developed an adaptive quantum approximate optimization-based model predictive control strategy to enhance energy efficiency and drive decarbonization in buildings. The approach achieved a 6.8% improvement in energy efficiency and a 41.2% reduction in carbon emissions.
A team of researchers has successfully observed the distribution of elements in a lithium button cell during 10,000 charge cycles using non-destructive X-ray methods. The study reveals that manganese dissolves from the NMC cathode and migrates to the carbon anode, leading to further reactions and processes.
A new study found that damage to the medial prefrontal cortex (mPFC) makes people more likely to be influenced by other people's impulsive decisions. The researchers also discovered that this type of brain damage is linked to increased impulsivity, even before being influenced by someone else.
A novel construction material FHPRC boasts excellent mechanical properties and is suitable for super-high-rise structures. The research optimizes tensile behavior by combining UHPC with high ductility and crack control capacity of engineered cementitious composite.
Researchers at University of Turku discovered a new biomarker that correlates the thickness of inflammatory cell rim surrounding brain lesions with disease severity and speed. The wider the rim, the more aggressively the disease advances, allowing for earlier treatment identification and evaluating drug candidates.
A new study highlights the success of a financial toxicity tumor board in reducing cancer treatment costs. The board has assisted over 9,321 patients with copay assistance and provided free medication to 16,495 patients, resulting in total savings of $393 million.
Scientists at HIRI develop peptide nucleic acid-based compound FUS79, which inhibits Fusobacterium nucleatum growth and exhibits strong activity against five fusobacterial strains without affecting other bacteria. This breakthrough has potential to accelerate research in targeted antibiotics for cancer treatment.
A new study found that increased perceived stress can lead to worsened respiratory symptoms and decreased quality of life in individuals with chronic obstructive pulmonary disease (COPD). The study also examined the association between stress and platelet activation, oxidative stress, and systemic inflammation.
Researchers found novel prognostic scores, such as MELD 3.0/GEMA-Na, exhibit superior discrimination and predictive ability for all-cause mortality up to two years in hospitalized patients with cirrhosis. The study suggests these scores are essential for risk stratification and may improve patient outcomes.
Researchers at University of Seville have discovered patulin and xestoquinol as inhibitors of DNA topoisomerase 1, a key enzyme in DNA metabolism. These natural compounds may provide a new class of anticancer drugs by preventing DNA cuts from being ligated.
A team of researchers from Jinan University has developed a metasurface-based imaging technique that can precisely measure the intensity, phase, and polarization of arbitrary light field distributions in a single exposure. The system uses optimized metasurface structural parameters to diffract incident light fields into sub-images that...
Despite a net gain of over 10,000 hectares in forest cover from 2000 to 2020, the Yangtze River Delta's forests experienced significant losses due to urbanization and agriculture. The study found that four times more carbon was emitted than taken up, highlighting the need for sustainable forest management.
A new report in Psychological Science in the Public Interest reveals that children learn best when instruction combines factual grounding, brief timed practice, and discussion to deepen knowledge. The researchers propose an evidence-based approach to foster arithmetic fluency, which is essential for future math skills and success.
A new satellite developed by Chalmers University of Technology will help monitor and measure the world's forest biomass. The system enables precise measurements of forest carbon stocks, aiding efforts to combat climate change.
A study found that most head-and-neck cancer survivors who underwent radiation don't know about survivorship care, despite grapple with side effects such as dry mouth, swallowing problems, and psychological distress. The survey also found that 40% of survivors still struggle with dry mouth and nearly a quarter reported trouble swallowing.
Researchers at KIMS have created a phosphorus-based cyanide-free silver plating process for semiconductors and electronic components, eliminating toxic substances. The technology produces uniform and stable silver thin films while simplifying the plating process.
New York dairy farms achieve low greenhouse gas emissions by producing high-quality crops and managing manure efficiently. The study provides a regional baseline for dairy farm emissions, offering opportunities for farmers to reduce emissions and increase productivity through sustainable practices.
A new study offers fresh perspective on how education systems can adapt to the challenges and opportunities of artificial intelligence. The study proposes a spatiotemporal framework for transforming education, including innovative strategies such as self-directed learning, student-centered pedagogy, and personalized assessments.
Researchers found that a 2%-3% starch-to-cheese ratio produces the smoothest sauce and advise letting water cool before adding cheese. They provide a scientific recipe for making cacio e pepe at home, based on their experiments.
A new study presents RMC-6236, a powerful inhibitor of RAS genes, showing promise in combination with other treatments. The study suggests that combining RMC-6236 with chemotherapy and targeted therapies could overcome therapy resistances and improve therapeutic outcomes in pancreatic cancer.
A new study emphasizes the importance of early education on bladder health and urinary tract problems during menopause, particularly for women using hormones. The study found that premenopausal women reported using hormones more often than perimenopausal or postmenopausal women, who experienced worse bladder health and function.
AIC100 demonstrated encouraging responses and an acceptable safety profile in patients with two types of advanced thyroid cancer, including anaplastic thyroid cancer (ATC) and relapsed/refractory poorly differentiated thyroid cancer (PTDC). The therapy showed significant tumor shrinkage and disease control in 56% of patients.
The AcrOSS platform features a three-layer architecture to manage UAS traffic, improve pilots' situation awareness with augmented reality, and ensure safe integration into controlled and uncontrolled airspace. Experimental tests showed promising results, but improvements are needed for ergonomics and integration between components.
A new robotic system utilizes optically-induced dielectrophoresis (ODEP) for the classification and analysis of patient-derived endometrial stromal cells. The system enables precise micromanipulation and measurement of single cells, providing insights into cell properties and responses to nonuniform electric fields.
A new study reveals that individuals with anxiety and depression tend to focus on jobs where they feel less confident, rather than those where they perform well, leading to persistent low self-belief. Positive feedback boosts overall self-belief, while negative feedback reduces it in all participants.
Researchers can now study microstructures inside metals, ceramics, and rocks with X-rays in a standard laboratory without needing a particle accelerator. The new technique, lab-3DXRD, enables quick analysis of samples and prototypes, providing more opportunities for students.
A new research institute at Tufts University, supported by a $11.5 million sponsorship, will focus on materials science and engineering to advance sustainable energy solutions. The institute aims to develop cleaner, safer, and more sustainable energy technologies, including renewable material-based batteries.
Researchers developed an advanced microscopic method to map residual stress in ultra-narrow weld zones, revealing the impact on P91 steel's strength and brittleness. The findings provide critical insights for designing safer and longer-lasting fusion energy systems.
Researchers unveiled an ultra-sensitive hydrogen sulfide sensor with extraordinary sensitivity, rapid response, and resilience. By leveraging exceptional points, the team amplified signal response and detected trace gases at 2 ppm with a lightning-fast response time of under 10 seconds.
A harmful form of tau protein directly damages blood vessels in the brain, leading to inflammation and weakening the brain's protective shield. The discovery highlights the importance of focusing on early neurovascular changes mediated by tau to prevent or slow down damage to the blood-brain barrier.
A novel approach to analyzing human blood plasma's low-abundant N-glycoproteome has been developed, enabling the reliable identification of rare and modified glycans. This workflow can detect glycoproteins with concentrations as low as 6.31 pg·mL−1, expanding the range by five orders of magnitude.
Fraunhofer IAF presents a bidirectional 1200 V GaN switch with integrated free-wheeling diodes, enabling more efficient power electronics for energy generation and mobility. The switch can be used in grid-connected power converters and electric drive systems.
Tropical cyclones significantly reduce school enrollment, especially for girls in areas unaccustomed to frequent storms. The study found that exposure to any cyclone at preschool age decreases the likelihood of starting primary school by 2.5%, with a maximum decrease of 8.8% after intense storms.
Researchers found no evidence of dancing or infant-directed song among the Northern Aché population in Paraguay. However, they do use playful speech and other methods to calm infants. The study suggests that dance and lullabies are learned behaviors that require cultural transmission.
A new clinical study has treated its first patient with a novel therapy aimed at difficult-to-treat melanoma skin cancer tumors. The treatment uses modified immune-system T cells to target PRAME, a peptide found in many melanoma tumor cells.
Researchers developed a wire-embedded culturing device for noninvasive signal recording from lollipop-shaped neural spheroids, providing insights into neural circuitry and dynamics. The device supports culture and growth of neural spheroids while facilitating real-time monitoring of interior signals.
A study found that female cancer survivors were 69% more likely to experience cancer-related fatigue and 58% more likely to experience depression than male survivors. This can lead to a decrease in recreational physical activities and overall quality of life.
A cohort study found that vaccination against influenza alone or with COVID-19 was associated with a small but temporary change in menstrual cycle length. This finding may help clinicians confirm the utility of vaccination for patients concerned about menstrual side effects.
A new study published in Scientific Reports reveals that audio quality severely affects dogs' ability to recognize and respond to recorded words. Dogs excelled at responding to direct human speech, but struggled with AIC buttons, which lost frequencies necessary for conveying human speech.
Researchers discovered that magnetar flares can produce the universe's heaviest elements, including gold and platinum. The discovery resolves a decades-long mystery concerning a bright flash of light and particles spotted by a space telescope in 2004.
A new CAR-T therapy, HSP-CAR30, has achieved positive results in a high proportion of patients with refractory CD30+ lymphoma. The treatment promotes the expansion of memory T cells, leading to durable responses and improved clinical outcomes.
Incidence-based mortality declined by 83.5% from 9.70/100,000 to 1.47/100,000 among women ages 20-49 between 2010 and 2020. Luminal A had the most pronounced decline in all subtypes.
Researchers at TUM developed an AI-powered algorithm to predict kidney damage in prostate cancer patients undergoing lutetium-177 PSMA therapy. Early detection could enable personalized treatment adjustments to prevent organ damage.
A study by Complexity Science Hub found that in 7.54% of DAOs, a single contributor controlled decisions due to concentrated governance tokens. This raises concerns about the true level of democracy in these organizations, which aim to distribute power and promote fairness and transparency.
A new study from the University of Surrey reveals that deregulated banks have led to a significant shift in corporate earnings management strategies, with companies opting for riskier real earnings management (REM) over accrual-based earnings management (AEM). This shift poses long-term risks to sustainability and innovation.
A national survey reveals worsening crisis in the nursing profession, with experienced nurses sending distress signals. Key findings include a troubling paradox between hopeful students and distressed experienced workers, highlighting the need for bold action to stabilize the profession.
A UMass Amherst graduate student's groundbreaking discovery reveals that neutral polyzwitterions take sides in the presence of electrical stimuli, contradicting conventional wisdom. The study opens new avenues for biomedical research, including protein analysis and drug delivery.
A new study finds that ocean-based carbon dioxide removal (CDR) and storage in German waters is feasible but with limitations, such as local marine conditions and required materials, energy, and infrastructure. Only five methods were shortlisted for implementation in German North Sea and Baltic waters.
Researchers from the University of Surrey warn that manufacturers who fail to adopt digital transformation will be left behind. By harnessing emerging technologies like chatbots, digital twins, and AR/VR, manufacturers can improve customer centricity and enhance their value proposition.
Researchers developed a new method to investigate karst features in urban areas using ambient noise tomography. The technique improved the resolution of seismic imaging and provided high-resolution images of subsurface structures, contributing to better geological hazard prevention and control.
Scientists have developed a method for safely assessing farmland abandoned after the Chornobyl nuclear accident, opening the way for potentially reclaiming thousands of hectares. The study found that crops can be grown safely in most areas with proper monitoring and adherence to Ukrainian food safety regulations.
A world-first clinical trial is being launched in Melbourne, Australia to assess the potential of tumour organoids to predict which chemotherapy drugs will work for newly diagnosed patients with bowel cancer. The trial has the potential to transform current treatment selection practices and improve survival rates and quality of life.
A cohort study found associations between pre-pregnancy overweight, smoking during pregnancy, and formula-feeding with adverse cardiovascular health trajectories in early childhood. The study suggests that addressing these factors through interventions may optimize cardiovascular health in children.
The EBDM system effectively controls membrane fouling, enhances effluent quality, and improves methane productivity in wastewater treatment. The electric field modifies the physicochemical properties of the biomass, reducing the fouling potential and promoting microbial metabolism.
Menachem Elimelech, a renowned leader in desalination and water purification, received the Sidney Loeb Award for his pioneering contributions to membrane-based water treatment technologies. His research focuses on developing advanced membranes and energy-efficient processes for desalination and wastewater reuse.
Dae Hyun Kim, MD, MPH, ScD, has been promoted to associate director of the Marcus Institute for Aging Research. He will help develop the institute's new strategic plan and support research on frailty, Alzheimer's disease, and other aging-related challenges.
Researchers from the University of Vienna and EPFL Lausanne found high concentrations of rubber additives in bouldering gym air, similar to car tires. The study suggests that these substances do not belong in the air we breathe, highlighting the need for better ventilation and cleaner climbing shoe materials.
A new UK study found that personal values, particularly frugality, are more influential in shaping sustainable food choices than environmental attitudes. Researchers suggest focusing on everyday values people already live by to inspire lasting change.
A recent study suggests that highly diverse microbial ecosystems may actually decrease stability under stress conditions. In contrast, low-diversity ecosystems often exhibit increased growth rates and community stability when faced with starvation or high salinity.
A new curriculum framework helps train future family physicians to integrate AI into their practice, addressing a critical gap in medical training. The AIFM-ed framework provides a structured road map for medical educators to bridge the AI gap, ensuring that future doctors are clinically competent and technologically fluent.
A new report from Flinders University reveals that Australia is facing a silent public health crisis due to poor sleep habits. The report outlines four priority actions to address the issue and calls for urgent action from policymakers to bring sleep to the forefront of the country's health agenda.
Patients undergoing CAD/CAM-assisted free fibula flap reconstruction showed reduced long-term complications, including hardware removal, compared to conventional methods. CAD/CAM techniques also improved efficiency and accuracy, with shorter operating room times.
A recent University of Georgia study found that a popular smartphone application frequently reports lower temperatures than direct on-site measurements, potentially leading to safety concerns. The app also underestimated the necessity of activity modifications to mitigate heat-related risks.
A non-risk-based lung cancer screening approach using low-dose computed tomography (LDCT) in Chinese populations detects a significant number of early-stage lung cancers. The study found that incorporating non-high-risk individuals into screening programs can lead to a greater detection rate and improved patient outcomes.
A study led by Paolo Padoan reveals that young stars gain material from their surroundings through Bondi-Hoyle accretion, making planetary disks larger and more durable. This revised understanding resolves long-standing observational discrepancies and forces substantial revisions to current models.
Researchers have discovered that inhibiting the metalloprotease ADAM19 can reduce gut inflammation and cell aging markers across species. The study found that blocking ADAM19 reduced gut damage and inflammation in fruit flies, mice, and human cells, offering a promising path for creating treatments to maintain healthy tissues.
Researchers reconstructed metal pollution history in São Paulo using sediment cores, revealing three periods of increasing pollution. The study highlights the importance of sediments as environmental indicators and offers insights for conservation efforts.
Research found that negative expectations have a stronger and longer-lasting impact on pain perception than positive ones. The study showed that nocebo effects, where participants expect a negative outcome, were more powerful and persistent than placebo effects, with implications for patient-practitioner communication.
A study found that satisfying intimate relationships and general social support can reduce cognitive problems experienced by breast cancer patients undergoing chemotherapy. The research suggests that couples therapy could be a helpful option for partnered patients, while oxytocin levels decreased significantly during treatment.
A study found that genetic predisposition to higher muscle strength is associated with lower all-cause and cardiovascular mortality in aging men. The association remained significant even after adjusting for lifestyle factors such as smoking and body mass index.
This study explored the immune dynamics across different phases of HBV infection, identifying key factors influencing T cell function and liver priming. The research team uncovered distinct types of intrahepatic T lymphocytes and dual roles of DC-SIGN+ macrophages in modulating immune responses.
Researchers analyzed data from over 35,000 young people to capture how depression symptoms interact throughout adolescence. The study found that symptom patterns become more stable across age, with individuals more likely to experience persistent depression in adulthood.
A new poll by Harvard T.H. Chan School of Public Health and the de Beaumont Foundation finds that many Americans anticipate losing trust in public health recommendations with changes in health agency leadership. Despite stark divisions, there is bipartisan support for several key health priorities.
Recent rainfall patterns play a critical role in triggering humid heatwaves in tropical and subtropical regions. In drier regions, humid heatwaves are more likely during or just after periods of enhanced rainfall, while in wetter regions, they tend to follow at least two days of suppressed rainfall.
A Phase I clinical trial reveals that HSP-CAR30 CAR-T cell therapy promotes the expansion of memory T cells, leading to long-lasting responses and improved clinical outcomes in treated patients. The treatment exhibits a favorable safety profile, with no dose-limiting toxicities detected.
Researchers have discovered a way to enhance wheat plants' sugar signalling ability, increasing yields by up to 12%. The new technology uses a Trehalose 6-phosphate pre-signalling molecule to activate the pathway for starch synthesis, leading to increased photosynthesis and grain filling.
Researchers have demonstrated a new quantum sensing technique that surpasses conventional methods by counteracting the limitation of decoherence. The study's coherence-stabilized protocol allows for improved sensitivity and detection of subtle signals, with up to 1.65 times better efficacy per measurement.
The Korea Institute of Machinery and Materials (KIMM) has developed a twin-screw-based pretreatment technology that liquefies and homogenizes solid biological samples in under one minute. This innovation simplifies the analysis of specimens traditionally difficult to process, offering a new diagnostic platform for point-of-care testing.
Dr. Seymour Reichlin's remarkable career spanned five decades, marked by scientific excellence, mentorship, and generosity. His influence on neuroendocrinology has been profound, with ongoing contributions at age 100 revealing new insights into Alzheimer's disease and ecstatic mysticism.
Researchers identified unique biological mechanisms that cause premature aging in the brains of individuals with alcohol, opioid, and stimulant use disorders. Different substances appear to hijack the brain's natural aging rhythm through distinct molecular mechanisms, though some pathways are shared across different substance types.
A recent study found that women are more metabolically efficient under extreme conditions, closing the performance gap with men. Women's greater fat mass may contribute to this advantage, enabling them to complete longer distances without burning out.
Researchers developed promising α-synuclein PET tracers that can visualize protein aggregates in living patients, enabling earlier diagnosis and treatment monitoring. Tracers like [18F]C05-05 and [18F]ACI-12589 showed significant results in distinguishing synucleinopathies from healthy controls.
A new study identified 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), finding that improving unfavorable profiles could prevent up to 63% of SCA cases. Lifestyle habits and environmental factors were found to be the most impactful in preventing SCA cases.
A new analysis of population surveys estimates that exposure to di-2-ethylhexyl phthalate (DEHP) contributed to 356,238 global heart disease deaths in 2018, accounting for 13% of all global mortality. The study also found higher death risks in the Middle East, South Asia, East Asia, and Pacific regions.