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International Scientific Association for Probiotics and Prebiotics


Global scientific paper establishes first consensus definition of gut health

A global group of scientists and clinicians has established the first consensus definition of gut health, encompassing both physiological function and individual symptoms. The new framework provides a basis for measuring and improving gut health, with applications for researchers and clinical management of digestive health.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalNature Reviews Gastroenterology & Hepatology·TypeLiterature review·DateFeb 18, 2026

Exploring the impact of probiotics on gut microbiota disruption caused by antibiotics

A review of probiotics for restoring antibiotic-disturbed gut microbiota found limited conclusive evidence. While certain probiotics can reduce clinical symptoms like diarrhea and C. difficile colitis, the lack of standardization in measuring microbiota disruption and recovery hinders conclusions.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalNature Reviews Gastroenterology & Hepatology·TypeLiterature review·DateDec 16, 2024

Expert publication recommends considering dietary factors in probiotics and prebiotics research

A new perspective paper emphasizes the critical role of diet in shaping the efficacy of prebiotics and probiotics. The authors found that diet significantly affects gut microbiome composition and function, potentially impacting the success of these interventions. Researchers are urged to collect data on participants' background diets a...

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalNature Microbiology·TypeCommentary/editorial·DateOct 31, 2024

Realizing the benefits of probiotics in the neonatal intensive care unit requires high-quality products

A new study calls for collaborative efforts to improve probiotic manufacturing standards for preterm infants. The authors propose five action areas to optimize the safety of probiotic products, including collaboration between clinicians, pharmacies, and manufacturers.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalJAMA Pediatrics·TypeCommentary/editorial·DateJul 10, 2023

Evidence for the health benefits of consuming more live microbes

A new study found that increased consumption of live dietary microbes is linked to better health outcomes, including lower waist circumference and body mass index. The research suggests that a higher intake of fermented foods, raw fruits, and vegetables may support immune function and increase the diversity of microbes in the gut.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalJournal of Nutrition·TypeObservational study·DateMar 7, 2023

Scientific criteria for assessing the safety of probiotics

A new paper highlights the need for globally harmonized probiotic regulatory approaches, emphasizing the importance of comprehensive genomic characterization. It proposes a risk-tier system based on strain history and genome analysis, recommending more extensive testing for innovative strains before marketing.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalRegulatory Toxicology and Pharmacology·TypeLiterature review·DateDec 29, 2022

Experts agree on new global definition of 'fermented foods'

Experts have agreed on a new global definition of fermented foods, specifying the differences between them and probiotics. The definition covers thousands of different types of fermented foods from around the world and provides a starting point for further research into their effects on human health.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalNature Reviews Gastroenterology & Hepatology·DateJan 5, 2021

Can we improve our health with doses of safe, live microbes on a daily basis?

A group of seven interdisciplinary scientists published a review paper highlighting specific gaps in the research on live microbes and health outcomes. They argue that there is only weak evidence to date confirming the link between live microbes and better human health, and propose a plan for quantifying this relationship.

Group of international scientists align on a definition for 'synbiotic'

A group of international scientists has developed a new definition for synbiotics, outlining a mixture of live microorganisms and selectively utilized substrates that confer a health benefit on the host. The definition aims to clarify scientific ambiguity and provide a foundation for science-based claims about synbiotic health benefits.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalNature Reviews Gastroenterology & Hepatology·DateAug 21, 2020

Scientific analysis shows probiotic use is associated with fewer antibiotic prescriptions

A systematic review found that healthy infants and children taking probiotics are 29% less likely to receive antibiotics. Probiotics may reduce antibiotic use by reducing the incidence and duration of infections, making them a potential tool for physicians as an alternative to antibiotics.

SourceInternational Scientific Association for Probiotics and Prebiotics·JournalEuropean Journal of Public Health·DateSep 14, 2018