A new study found that individuals who experienced childhood adversity, such as poverty, illness, or death in the family, are at higher risk of developing type 2 diabetes in early adulthood. The study, conducted on a large population-based cohort, reveals that these adverse experiences can lead to increased inflammation, insulin resist...
A recent study published in JAMA Oncology reveals that disparities in cancer care are linked to differences between clinicians' and patients' identities. Younger, lower-income minorities were disproportionately affected by delayed care due to these identity differences.
The study of nematodes' body size can inform scientists' understanding of cellular growth, with the goal of discovering novel genes that control cell size and potential targets for cancer treatment. Nematodes are a model species for biological studies due to their quick growth rate and ability to produce hundreds of eggs.
Researchers at Chalmers University have successfully used a quantum computer to calculate the intrinsic energy of small molecules, demonstrating a new method called Reference-State Error Mitigation. This breakthrough has the potential to advance the boundaries of chemical calculations and simulate complex chemical processes.
A new drug, atogepant, has shown promise in preventing migraines for people who have had no success with other preventive drugs. In a preliminary study, participants taking the drug experienced fewer days with migraine compared to those taking a placebo.
Researchers found that an extra copy of a gene controlling synapse formation causes excessive inhibitory signaling in the brain of mice with Down syndrome. This may contribute to conditions such as autism, epilepsy, and bipolar disorder.
Researchers have developed a new method using co-thermal in-situ reduction of inorganic carbonates to produce high-purity CO with a selectivity of 95.8%, reducing carbon-dioxide emission and offering potential for green hydrogen production.
A team of researchers has identified a peptide that disrupts the interaction between alpha-synuclein and a protein subunit of cellular machinery, reducing its levels and promoting cell clearance. The study suggests a new therapeutic avenue for Parkinson's disease and other neurodegenerative conditions.
A novel model, TGFS, simulates the response of fruit growth and quality to environmental factors and cultivation practices. The study found that reducing nitrogen and water input can increase tomato fresh weight by 27.8-36.4% while increasing soluble sugar concentration up to 10%. This provides a promising tool for optimizing N and wat...
A new PANDA-project aims to develop and test an ear-EEG device that can screen patients for Alzheimer's and Parkinson's diseases. The technology measures brain electrical activity and sleep patterns, with the goal of identifying early signs of the diseases and enabling earlier diagnosis.
The rate of suspected suicide attempts by poisoning among children and adolescents ages 10-19 increased 30% during the COVID-19 pandemic compared to 2019. The most common substances involved were acetaminophen and ibuprofen, highlighting the need for comprehensive approach to suicide prevention.
Andrew Lupini, a scientist at Oak Ridge National Laboratory, has been elected Fellow of the Microscopy Society of America. He made significant contributions to aberration correction in scanning transmission electron microscopy, improving resolution and advancing the field.
Scientists have created a method to produce synthetic spider silk with eightfold higher yields than previous methods, making it a promising material for sustainable clothing production. The new silk fibers retain the desirable properties of enhanced strength and toughness while being lightweight.
Researchers have found that the subfornical organ senses circulating parathyroid hormone (PTH) and modulates its peripheral level. PTH then alters bone metabolism and remodeling, highlighting a critical role of the brain-parathyroid-bone axis in maintaining bone homeostasis.
Researchers at Moffitt Cancer Center have identified a critical pathway in the development of MYC-driven lymphoma, involving the chemical modification of eIF5A with hypusine. Inhibiting this process prevents lymphoma development and progression in mouse models, offering new therapeutic strategies.
A study by University of Cologne researchers found that 25-35% of permafrost's organic carbon is bound to mineral particles, making it harder for microorganisms to utilize. This complex binding process affects the release of greenhouse gases from thawing permafrost.
A new PSMA PET scoring system, the tumor-to-salivary gland ratio (PSG score), can predict patient response to <sup> 177 </sup> Lu-PSMA therapy. Patients with high PSG scores had longer PSA progression-free survival and overall survival rates.
A study by researchers at the University of Michigan found that an extra copy of the DSCAM gene in mice with Down syndrome causes improper neuron development and excessive inhibition. This discovery suggests modulation of DSCAM expression levels could be a viable therapeutic strategy for repairing synaptic deficits seen in Down syndrome.
Cedars-Sinai investigators have discovered a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using human induced pluripotent stem cells. The new approach uses cells derived from iPSCs that are renewable, scalable, and can delay disease progression in rodents.
A recent study from Aarhus University found that music used for studying and sleeping share similar characteristics, such as slow tempo and repetitive patterns. The study suggests that these similarities can be attributed to the calming effects of the music on the brain, creating a conducive environment for both tasks.
A four-year field experiment in Estonia reveals that recycling phosphorus-rich lake sediments can sustain grass biomass yield and provide essential nutrients. However, the study also highlights potential environmental risks associated with sediment application methods.
A new study finds that economic growth is insufficient to eliminate dog-mediated rabies, highlighting the need for targeted interventions such as improved pet ownership and education in vulnerable communities. The research uses data from over 100 countries to show a strong association between poverty and higher death rates from rabies.
Researchers study how choice of network framework affects synchronization, finding that hypergraphs promote easier synchronization than simplicial complexes. The choice of representation can influence the outcome, suggesting structural heterogeneity is key to understanding collective dynamics.
A new study on nematode worms reveals that they react to cannabinoids in the same way as humans, increasing hunger for favorite foods and decreasing hunger for non-favored foods. The discovery emphasizes the commonality of cannabinoid effects across species.
A new study by Columbia University Mailman School of Public Health finds that water arsenic levels are associated with higher urinary arsenic among the U.S. population, especially in public water supplies in the West and South regions. The researchers found that private well users and those in public water systems have higher urinary a...
Researchers developed a method to heal and recycle garnet electrolytes with Li dendrite penetration through heat treatment, increasing ionic conductivity and relative density. The recycled pellets showed improved densification and suppressed Li dendrite penetration, enabling higher critical current density.
Researchers at POSTECH have successfully developed perovskite solar cells using novel additives, achieving high power conversion efficiency and fill factor. The use of alkylammonium formats enables the elimination of surface defects, leading to more stable and efficient solar cells.
The SuperBIT telescope has begun capturing high-resolution images of the Universe on its first research flight. It is investigating the mystery of dark matter, which is thought to be made up of particles that can bounce off each other during galaxy collisions.
The team successfully entangled two qudits with unprecedented performance, enabling faster and more robust quantum computing. This breakthrough could lead to significant advancements in fields like chemistry and physics.
The study found associations between prenatal maternal stress life events and adverse neurodevelopmental outcomes in offspring. DNA methylation likely plays a role in these associations. The research provides new insights into how the fetal environment influences neurodevelopment, metabolism and immunologic functions.
A preclinical study suggests that abnormal immune activity in astrocytes is sufficient to cause cognitive deficits in dementia. Astrocytes produce excessive immune messengers, activating neurons and leading to hyperactivity.
TRIO Pharmaceuticals is developing a proprietary platform of dual-action tumor immunity-enhancing drugs aimed at treating cancers with high unmet medical needs. The company's innovative approach selectively eliminates immunosuppressive cells, enhancing antitumor activity.
Scientists recorded brain activity in wild elephant seals, revealing they take short naps during deep dives, averaging just 2 hours of sleep per day at sea. They switch between getting a lot of sleep on land and less when foraging at sea.
Bar-Ilan University researchers found that large and heterogeneous complex networks exhibit enhanced stability due to non-random patterns of interaction, contradicting Sir Robert May's original prediction. This discovery offers new guidelines for designing stable infrastructure networks and protecting fragile ecosystems.
Researchers at Nagoya University have successfully synthesized barium titanate nanosheets with a thickness of 1.8 nanometers, the thinnest freestanding film ever created with ferroelectric properties. This achievement paves the way for the development of smaller and more efficient devices such as memories and capacitors.
Consuming insects like crickets can contribute to healthy gut microbiota and provide essential nutrients. Research by CSU professor Tiffany Weir and colleagues highlights the potential benefits of edible insects on human health, including increased prebiotic effects and reduced intestinal inflammation.
Scientists at ETH Zurich have successfully created a substantially heavier Schrödinger cat by putting a small crystal into a superposition of two oscillation states. The resulting 'cat' weighs around 16 micrograms, making it the fattest quantum cat to date.
Scientists have identified a new emergency brake mechanism that prevents bladder cells from becoming cancerous, even when cancer-promoting genes are active. This discovery could lead to new therapeutic targets for bladder cancer treatment.
A new liposome-based method aims to kill periodontitis-causing leukotoxin while protecting immune cells, providing an alternative treatment for aggressive gum infections. The approach has potential applications against a range of bacteria and could help combat antibiotic resistance.
A new study in Nature Photonics demonstrates that quantum entanglement improves the precision of optomechanical sensors, enabling more accurate navigation without GPS. The technology also holds promise for detecting dark matter by identifying subtle forces.
A new study suggests that private land conservation in Brazil's Cerrado region can protect up to 14.5% of threatened vertebrate species' ranges. The analysis found that restoring private protected areas is an important conservation goal, warranting special funds and attention.
A new study by University of South Australia researchers found that golfing reduces psychological distress and improves general health in people with osteoarthritis. Golfers experience lower levels of psychological distress compared to the general population.
Researchers at Arizona State University have designed a drone with an inflatable frame that can absorb impact forces and provide collision resilience. The drone's stiffness is tunable, allowing it to physically interact with its surroundings and accomplish tasks like perching, which involves controlled collisions.
Researchers developed machine-learning algorithms to generate proteins with specific structural features, enabling the creation of biologically inspired materials. The models can produce millions of new protein ideas in a few days, allowing scientists to explore unique applications.
A massive crowd-sourced study of 327 co-authors at 186 institutions from 14 countries found that ChatGPT scored 47.4% on accounting exam questions, while students averaged 76.7%. Despite struggles with short-answer and higher-order questions, ChatGPT showed promise in improving teaching and learning processes.
A new study reveals that beaver ponds with deeper sediments can store up to 15% of the nitrogen that enters them. This finding is crucial for understanding nitrogen pollution in rivers and streams, where beavers play a key role in shaping ecosystems.
A study reveals that climate change will lead to increased flood risks globally, with 1.86 billion people living in areas prone to extreme flooding. The research team developed a new approach to create high-resolution future flood hazard maps using climate change simulations and compared the results with historical maps.
A study published in Scientific Reports warns that sea level rises could lead to the flooding of sea turtle breeding grounds in Australia, Dominican Republic, Costa Rica, and the USA. The findings suggest that flooding could contribute to the loss of turtle nesting sites and negatively impact turtle populations.
Researchers found that punctuation marks follow a Weibull distribution across seven Western languages, with some differences between languages but no exceptions. The study also revealed the English language to be the least punctuated, while Slavic languages relied on punctuation most.
Researchers found that cellophane bees produce a liquid food for their larvae using lactobacilli bacteria, which are highly active and play a crucial role in their nutrition. This unique fermentation-based strategy has important implications for bee health and ecosystem ecology.
Faults in Ridgecrest, California were sensitive to solid earth tidal stresses before the July 2019 earthquake sequence. Researchers found a strong signal of tidal modulation after 2018, but it's unclear if it triggered the earthquake. The study suggests that tidal stresses may be an indicator of upcoming earthquakes.
Researchers from the University of South Florida and EPA developed a new classification system to target wetland restoration and protection. The system categorizes freshwater wetlands into four classes based on their proximity to streams, demonstrating the effects of wetlands on water quality at a continental scale.
A team of researchers developed a multi-organ chip on-a-chip that applies 3D cell printing technology to closely replicate the pathological environment of type 2 diabetes. The chip shows a correlation between visceral fat and T2D, as well as impaired retina cell function, indicating potential complications.
A meta-analysis of 33,541 cancer patients found that advance care planning was associated with lower odds of aggressive end-of-life care, including chemotherapy and intensive care. Patients who engaged in advance care planning were also more likely to complete do not resuscitate orders.
A study of 70 patients found that donor lungs remained healthy and viable for transplant up to four times longer when stored at 10 degrees Celsius compared to the current standard. This breakthrough could increase donor organs and change practice worldwide, reducing hospital resources and improving patient outcomes.
The study developed conductive hydrogels with high sensing performance, excellent stretchability, and tensile strength, thanks to the use of cationic cellulose nanofiber-dispersed liquid metal. The hydrogels demonstrated a very high sensing sensitivity and good repeatability and durability.
Researchers at McGill University found that analyzing gene activity can classify brain diseases into five primary groups, improving diagnosis accuracy. The study identified previously unknown relationships among diseases, such as language development disorders and obsessive-compulsive disorder, which share common genes and cell types.
A recent study by McGill University found that short exposure to bright light before night shifts can significantly reduce fatigue and errors among nurses. Nurses who received bright light exposure made fewer errors and slept better after their shifts.
Humpback whales use sandy bays to remove dead skin cells and barnacles through 'sand rolling' behavior. This exfoliation method helps maintain a healthy bacterial skin community, reducing drag and energy loss.
Researchers found tsunami deposits in a coastal mangrove pond that suggest a massive magnitude 8.7 or larger earthquake triggered the tsunami, potentially impacting both Caribbean and Atlantic coasts of Puerto Rico. The discovery provides valuable insights into seismic risk in the region.