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Princeton University, Engineering School


Sorting cells’ inner structures provides new path to drug development

Researchers at Princeton University used AI to analyze how drugs affect cell structures, finding new shapes linked to disease and discovering a novel drug effect. The neural network identified cap, necklace, and flower shapes, with the latter indicating a previously unknown role of an enzyme in maintaining nucleolar organization.

SourcePrinceton University, Engineering School·JournalCell·TypeExperimental study·DateJun 12, 2026

Hidden math link helps designers build fantastic shapes

Researchers at Princeton University developed a system to mimic natural structures' microstructural patterns and mechanical properties. By combining origami and tensegrity, they found that the same equation describes both engineering structures, enabling designers to create irregular shapes with less computational complexity.

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 4, 2026

New 3D device harnesses living brain cells for computing

Researchers at Princeton University have developed a 3D device that combines living brain cells with advanced electronics to recognize patterns using computational techniques. The device creates a vast 3D network of neurons that can be used for computation, offering a potential solution to the energy bottleneck in modern AI technology.

SourcePrinceton University, Engineering School·JournalNature Electronics·TypeExperimental study·DateApr 23, 2026

No motors? No gears? No problem.

Soft robots could work as medical implants, deliver drugs inside the body, and explore dangerous environments. The researchers designed a reconfigurable robot that can move repeatedly without degradation, using targeted heating to control motion and embedded temperature sensors for closed-loop control.

SourcePrinceton University, Engineering School·JournalAdvanced Functional Materials·TypeExperimental study·DateApr 9, 2026

Many nations underestimate greenhouse emissions from wastewater systems, but the lapse is fixable

Research from Princeton University reveals that nations globally underreport greenhouse gas emissions from wastewater facilities by up to 27%. Accurate estimates are crucial for sound public reporting and practical decision-making in the wastewater sector. The study finds that wastewater systems offer strong options for emissions reduc...

SourcePrinceton University, Engineering School·JournalNature Climate Change·TypeData/statistical analysis·DateFeb 26, 2026

Optics research uses dim light to produce bright LEDs

Researchers at Princeton University have developed a new technique to convert low-energy light into high-energy LEDs, improving the ability to upconvert green light to blue or ultraviolet light. The method uses plasmonics to boost upconversion on a thin metal film, reducing the power needed by 19 times compared to previous setups.

SourcePrinceton University, Engineering School·JournalNature Photonics·TypeExperimental study·DateJan 7, 2026

Looking for the perfect fold? It’s frustrating.

Researchers at Princeton University have developed a new type of origami that changes its shape and properties in response to external stimuli. By introducing elastic components, they can execute precise folding patterns not previously possible. This technology has potential applications in prosthetics, antennas, and other devices.

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateSep 4, 2025

Researchers send a wireless curveball to deliver massive amounts of data

Researchers at Princeton University have developed a machine-learning system that can shape ultrahigh frequency transmissions to avoid obstacles, allowing for real-time adaptation in dynamic environments. This breakthrough could enable the widespread adoption of sub-terahertz frequencies for high-speed data transmission in applications...

SourcePrinceton University, Engineering School·JournalNature Communications·TypeExperimental study·DateAug 18, 2025

Enhanced geothermal systems: An underground tech surfaces as a serious clean energy contender

A new Princeton analysis suggests that enhanced geothermal systems (EGS) could become the third most significant clean energy technology in the US by 2050. EGS has the potential to deploy up to 250 gigawatts of electricity, which is comparable to the current grid capacity of 1,200 gigawatts.

SourcePrinceton University, Engineering School·JournalJoule·TypeComputational simulation/modeling·DateJul 10, 2025

Major autism study uncovers biologically distinct subtypes, paving the way for precision diagnosis and care

Researchers identified four clinically and biologically distinct subtypes of autism, each with distinct developmental, medical, behavioral, and psychiatric traits. The study linked subtypes to genetic profiles and developmental trajectories, offering new insights into the biology underlying autism.

SourcePrinceton University, Engineering School·JournalNature Genetics·TypeData/statistical analysis·DateJul 9, 2025

New tool allows researchers to track assembly of cells’ protein-making machines

Researchers developed a technique to peer inside the nucleolus and reveal its hidden system of creation, allowing them to watch RNA molecule movement and track protein-making machine assembly. The new method uses advanced imaging and genomics techniques without destroying the cell, providing a precise spatial and temporal map.

SourcePrinceton University, Engineering School·JournalNature·TypeExperimental study·DateJul 2, 2025

Collaboration can unlock Australia’s energy transition without sacrificing natural capital

New research led by Princeton University demonstrates that Australia can fully decarbonize its domestic and energy export economies by 2060 while avoiding harm to important areas for biodiversity outcomes. The study proposes a 'traffic-light' approach for siting renewable infrastructure, identifying suitable lands for development and t...

SourcePrinceton University, Engineering School·JournalNature Sustainability·TypeComputational simulation/modeling·DateJun 3, 2025

Physical cloaking works like a disappearing act for structural defects

Engineers at Princeton University and Georgia Institute of Technology have created a method to reinforce structures without creating new weaknesses. The approach uses microstructures designed to protect against multiple loads, allowing designers to counter various stresses simultaneously.

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 5, 2025

From research to real-world, Princeton startup tackles soaring demand for lithium and other critical minerals

A new Princeton startup has developed a technology to boost minerals production from evaporation ponds, doubling the efficiency of lithium and nitrate extraction. The innovation uses a black disc with an anti-fouling coating to accelerate evaporation rates, alleviating the need for large-scale construction of new ponds.

SourcePrinceton University, Engineering School·JournalNature Water·TypeExperimental study·DateApr 21, 2025

AI technique boosts climate change defenses

Researchers used reinforcement learning to simulate coastal defense strategies against sea level rise and flooding, finding dynamic seawalls to be more cost-effective than traditional methods. The study aimed to address uncertainty in long-term climate change mitigation efforts and provide a flexible approach for communities to prepare...

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences (dupe)·TypeComputational simulation/modeling·DateMar 19, 2025

These bacteria perform a trick that could keep plants healthy

Researchers at Princeton University discovered that certain bacteria can reduce a plant's immune activity, allowing its roots to grow longer. The study identified an enzyme produced by one of these bacteria as the key factor in this process, which could have implications for understanding microbiome interactions with host immune systems.

SourcePrinceton University, Engineering School·JournalCell Reports·TypeExperimental study·DateJan 2, 2025

Electric vehicle transition could create unwanted air pollution hotspots in China and India

Researchers warn that refining nickel, cobalt, and other minerals for electric vehicle batteries could increase sulfur dioxide emissions by up to 20% in China and India. The study highlights the need for countries to think strategically about building clean supply chains as they develop decarbonization plans.

SourcePrinceton University, Engineering School·JournalEnvironmental Science & Technology·TypeComputational simulation/modeling·DateDec 16, 2024

For these little robots, two heads are better than one

Scientists at Princeton University develop a system of two robots connected by flexible tether, enabling them to solve complex problems like maze navigation and object gathering. The innovative approach harnesses physical characteristics rather than digital calculation to achieve remarkable abilities.

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 30, 2024

Bird wings inspire new approach to flight safety

Researchers at Princeton University developed a new technology inspired by bird feathers, which improves flight performance and prevents stalling. The covert-inspired flaps deploy in response to changes in airflow, offering an inexpensive and lightweight method to increase flight performance without complex machinery.

SourcePrinceton University, Engineering School·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateOct 28, 2024

Retiring coal plants with climate and equity in mind

New research led by energy systems modelers at Princeton University demonstrates that retiring coal plants based on minimizing costs could leave other climate and equity benefits on the table. Retiring half of Pennsylvania's coal plants under a climate- or equity-focused strategy could reduce carbon emissions, air pollution, and deaths...

SourcePrinceton University, Engineering School·JournalEnvironmental Science & Technology·TypeComputational simulation/modeling·DateOct 10, 2024

Simple shift could make low Earth orbit satellites high capacity

Researchers developed a system to effectively split transmissions from a single antenna array into multiple beams without additional hardware, allowing satellites to overcome the one-to-one user ratio. This enables significant reductions in cost and power consumption, potentially leading to fewer satellites, smaller satellites, or both.

SourcePrinceton University, Engineering School·JournalIEEE Transactions on Signal Processing·TypeComputational simulation/modeling·DateSep 13, 2024

Pennsylvania policymakers underestimate public support for solar projects, survey says

A survey of Pennsylvanians and policymakers reveals bipartisan support for solar energy and other renewables, but elected officials underestimate their constituents' preferences. The study highlights the need for clear communication between the public and local representatives to ensure informed decision-making about energy projects.

SourcePrinceton University, Engineering School·JournalNature Energy·TypeSurvey·DateAug 5, 2024

Research shows how common plastics could passively cool and heat buildings with the seasons

Researchers at Princeton and UCLA developed a passive mechanism to cool buildings in summer and warm them in winter by restricting radiant heat flows. Common materials like polyvinyl fluoride and plastics can be adapted for this purpose, achieving energy savings and thermal comfort beyond traditional building envelopes.

SourcePrinceton University, Engineering School·JournalCell Reports Physical Science·TypeExperimental study·DateJun 27, 2024

From seashells to cement, nature inspires tougher building material

Researchers at Princeton University have developed a new cement composite that mimics the strength and flexibility of seashells, increasing crack resistance and ductility. The composite, inspired by nacre's microstructure, exhibits improved fracture toughness and deformability, making it potentially tougher, safer, and more durable.

SourcePrinceton University, Engineering School·JournalAdvanced Functional Materials·TypeExperimental study·DateJun 11, 2024