Researchers developed a novel design paradigm for vectorial microlasers with designable topological charges using quasi-BIC Möbius-like correspondence in photonic-crystal slabs. This approach allows for programmable structured-light sources for integrated photonic circuits and multi-dimensional optical information encoding.
The MAMBO project developed innovative technologies to monitor biodiversity, including autonomous insect traps, camera traps, sound recognition models, and image analysis tools. These tools enable standardized data collection across multiple species groups, transforming how biodiversity is assessed in Europe.
Researchers at HKUST developed a crystal-solvate seeding strategy to reconstruct buried interfaces in perovskite solar cells, achieving higher efficiency and operational stability. The approach eliminated interfacial voids and introduced stable passivation phases, enabling scalable manufacturing.
The LHAASO discovery reveals an astonishingly efficient particle accelerator powered by PSR J1849-0001, exceeding theoretical limits and challenging current theories of particle acceleration. The system's gamma-ray luminosity is several times higher than that of the Crab Nebula.
The fossil discovery of a giant ichthyosaur with injuries in Northern Bavaria has provided new insights into the species' anatomy and behavior. The animal's modified skeleton, likely caused by injuries, suggests that it may have had to change its diet to survive.
Researchers found that a spherical-shell dynamo can exist in two stable equilibrium states, with tiny initial fluctuations determining the polarity. The study suggests that breaking this stable state is necessary to trigger magnetic reversals, possibly through mechanisms outside magnetohydrodynamic theory.
A new study by UNSW researchers shows how a neural network can detect blue whale songs with remarkable accuracy, using only one recording of a blue whale call. The model performed well on real-world recordings, even those that were not part of the training data.
Researchers have uncovered a new pathway to directly regulate glycogen levels in the body, offering potential therapeutic avenues for conditions like diabetes and heart disease. By studying ubiquitin's role in sugar storage, scientists have identified a new layer to a well-understood biochemical process.
Researchers at Tohoku University discovered a hidden mechanism in DNA damage caused by singlet oxygen generating abasic sites. This process is common and represents one of the main forms of DNA damage, alongside guanine-related types.
Researchers develop a novel surface polarization strategy that pushes device efficiency beyond 26% while dramatically enhancing operational stability. This approach utilizes intrinsic surface defects as anchoring sites for dipolar molecules, transforming flaws into functional advantages for interfacial engineering.
Researchers are developing a new wearable technology to monitor babies' movements and detect early signs of autism. The study aims to improve early identification and intervention, which is crucial for optimal developmental outcomes in autistic individuals.
A new study found that Washington's hepatitis C elimination initiative increased testing and treatment access, leading to reduced total care costs. Per-patient costs declined by over 45% as more people received treatment, suggesting a cost-effective approach to screening and treatment of healthy individuals.
A study published in Biophotonics Discovery uses spectral-focusing coherent anti-Stokes Raman spectroscopy to image human white matter microstructure. The method enables automated measurement of axon size and myelin thickness, revealing new insights into brain connectivity and behavior.
A new study from Tulane University found that extra sets of chromosomes in tumor cells make them more mobile and likely to engulf neighboring cells. This stress response triggers an abundance of proteins, reprogramming the cells for motility and phagocytosis.
A new species of hamster-sized mammal, Cimolodon desosai, has been discovered in the Upper Cretaceous El Gallo Formation of Baja California. The fossil, estimated to be 75 million years old, was found alongside dinosaur fossils and provides insights into the survival strategies of early mammals.
A new AI-based approach developed by UC Riverside professor Demetrius Lewis helps correct the misclassification of creative works due to shifting genres. The tool provides a more accurate representation of how a work was originally intended and received, reducing the risk of undervaluation for boundary-pushing projects.
Researchers developed a microfluidic platform that squeezes individual breast epithelial cells to measure their mechanical age, revealing an unexpected insight: older cells are stiffer and at higher risk of cancer. The AI-powered platform provides a non-genetic test for women with unknown genetic risks.
The European Society of Endocrinology organizes World Hormone Day to educate the public about hormone-related health issues. Global endocrine disorders affect millions worldwide, emphasizing the need for proper hormone balance.
A new study shows that while dental opioid prescription fills in the US have dropped by 27% since 2021, the rate remains higher than in other developed countries and the US territory of Puerto Rico. The study suggests that some US dentists are still overprescribing opioids.
Ultra-faint dwarf galaxies, tiny satellite galaxies of the Milky Way, can reflect conditions of the early universe, shedding light on galaxy formation and dark matter. Simulations suggest these small galaxies are sensitive to early radiation environment and can probe the universe's earliest climate.
Women diagnosed with cancer in pregnancy face significant emotional and financial challenges, including maternal guilt, exhaustion, and financial strain. Researchers emphasize the need for psychological support during treatment and post-treatment to mitigate long-term psychological impacts.
A major clinical trial found that real-time continuous glucose monitoring significantly improves blood glucose management in adults with type 2 diabetes treated with basal insulin. Participants using CGM showed greater reductions in HbA1c levels compared to traditional finger prick glucose monitoring.
A new ultra-thin optical film improves the quality of light used in LCD resin-based 3D printers, ensuring precise details and reducing printing errors. The film's design enhances collimation and uniformity, paving the way for affordable industrial or medical-grade products.
Researchers use tree rings and satellites to date changes beavers make to the tundra landscape as they spread northwards. The study provides evidence of beaver colonization in the region starting in 2008, with satellite analysis revealing a significant expansion of surface water between 2015 and 2019.
A study from the University of Nebraska-Lincoln found that interspersing realistic portrayals of motherhood alongside idealized posts can help sustain positive feelings and reduce shame among mothers. This balanced approach may mitigate some social media harms, particularly for those prone to social comparison.
A new composite scoring system, HOST-Factor, quantifies the functional state of the tumor microenvironment in pancreatic cancer. The study demonstrates the effectiveness of pulsed low-dose-rate chemoradiation in shifting the tumor microenvironment from a tumor-promoting to a tumor-restricting state.
Researchers found that antibiotics disrupt gut microbiota, suppressing protective immune system pathways and increasing severity of A. baumannii pneumonia. The study highlights the gut-lung connection as a potential therapeutic target for hospital-acquired lung infections.
A study led by UC Irvine researchers found that dopamine dysfunction in the entorhinal cortex contributes directly to impaired memory formation in Alzheimer's disease. Restoring dopamine levels using optogenetic techniques and Levodopa restored memory function in a mouse model of Alzheimer's disease.
A study of over 2,100 Australian adults found that a daily increase in ultra-processed foods can significantly impact attention span and cognitive function. Even among those who consume a healthy Mediterranean diet, the degree of food processing plays a critical role in damaging brain health.
New research reveals that the organization of electrons within a material determines its response to light. The study shows that moiré superlattices can be engineered to exhibit unusual properties by controlling electron arrangement.
A new report by Change Chemistry and UMass Lowell identifies the need for targeted government incentives to help businesses transition to more sustainable chemicals. The report details how carefully designed incentives can reduce risk, accelerate commercialization, and drive real market adoption.
A phase 1 clinical trial has started enrolling patients with symptoms of prion disease, evaluating the safety and tolerability of a small interfering RNA targeting the prion protein. The trial aims to slow disease progression and is supported by NeuroNEXT, a program of the National Institute of Neurological Disorders and Stroke.
A new mathematical model called LFSPRO was developed to predict the risk of Li-Fraumeni Syndrome. The model provides a more quantitative risk estimate for individuals who would benefit from testing but do not meet established criteria.
A new study by Femida Handy and Sara Konrath found that voting is associated with reduced mortality risk in older adults for up to 15 years. Voting predicts a lower risk of mortality, even when the candidate loses, suggesting that voting itself is more important than who was voted for.
A study published in PLOS Medicine has identified two new genetic pathways contributing to cardiometabolic disease, including heart disease and obesity. The research analyzed lipid metabolites and their link to disease, suggesting that targeting specific metabolic pathways could prevent or lower the risk of disease.
The new consensus statement provides updated guidance on CIED lead management, including extraction and management of traditional devices and newer technologies. The recommendations aim to reduce clinical challenges and morbidity within a rapidly evolving technological landscape, ensuring better quality of life for patients.
Researchers developed a two-step treatment using growth factors FGF2 and BMP2 to redirect fibroblast cells towards regeneration. The study suggests that regeneration may not be lost in humans but rather obscured by the healing process.
Researchers at McGill University have discovered that brief cold plasma treatment can significantly reduce the potential of peanuts to cause allergic reactions. The process alters protein structure and improves functional properties, enabling hypoallergenic peanut protein powder development for new products.
A recent study found that genetic variations in the vitamin D receptor polymorphisms can affect the protective benefits of vitamin D supplementation on diabetes risk. Individuals with certain genotypes showed a reduced risk of progressing to type 2 diabetes, while others received no benefit from vitamin D treatment.
Research from Lund University reveals that stiffer tumor tissue triggers a chain of molecular events driving cancer cells to invade surrounding tissue. The studies identified key proteins and pathways involved in this process, offering new insights into the mechanical properties of tumor microenvironments.
MIT researchers have developed an ultra-efficient microchip that can bring post-quantum cryptography techniques to wireless biomedical devices. The chip includes built-in protections against physical hacking attempts and is more than an order of magnitude more energy-efficient than prior designs.
The STEMI-DTU trial analyzed secondary endpoints, finding that major bleeding and vascular complications were associated with increased mortality in the control group. The study provided insight into the importance of technique and bleeding complications in heart attack treatments.
Researchers aim to determine the connection between circulating lipoprotein (a) and calcific aortic valve disease, with a focus on biomechanics and early detection. They will also explore how mechanical forces influence disease progression and treatment.
Researchers developed an AI-powered methodology to identify and count target viruses more efficiently than previous techniques. The new approach uses electrochemical impedance spectroscopy and machine learning to separate signals from noise, enabling quick and accurate readings across a wide range of titers.
Researchers found that people follow a two-stage process, sampling behaviors at first and committing once enough evidence accumulates. The Tolerance Principle predicts when people have seen enough regularity to treat a pattern as a rule despite some exceptions.
A new study analyzing Mount Everest expeditions spanning more than a century has found that death rates among climbers have declined significantly in recent decades. The research highlights improvements in safety measures such as fixed ropes, better weather forecasting, and increased oversight among climbing teams.
The study found that invasive reed facilitates the development of mosquito larvae, leading to increased adult populations. Removing invasive reed and restoring native vegetation can help mitigate this impact.
A study coordinated by the University of Trento has identified a gene therapy for individuals with cystic fibrosis caused by a specific mutation, offering new hope for those currently dependent on drugs. The therapy uses advanced gene editing technology to correct the DNA mutation responsible for the disease.
Researchers found memory cells in nasal tissue can reactivate to fight influenza, reducing viral replication and protection against more severe illness. These immune cells can be used to develop better nasal vaccines.
A new analysis by researchers at the University of Texas MD Anderson Cancer Center demonstrates that combination therapy consisting of fludarabine, cytarabine and G-CSF (FLAG) plus gemtuzumab ozogamicin (GO) or idarubicin (IDA) delivers strong long-term outcomes for patients with CBF-AML. The five-year overall survival rate reached 74%...
Researchers found that even in degraded forests, tree species can regenerate quickly, but vulnerable species are replaced by more resilient generalists, leading to a loss of diversity. The recovered areas are vulnerable to extreme events and climate change impacts, highlighting the need for forest conservation strategies.
Researchers estimate sepsis occurs in 1.3% of pediatric hospitalizations, resulting in a 10% mortality rate, and urges the need for immediate recognition and treatment. The study's findings highlight the importance of awareness among families to improve child survival rates.
A study has identified novel risk factors and therapeutic targets for Parkinson's disease, offering hope for future treatments. The researchers used a combination of computational and experimental approaches to distinguish between gene function changes that promote or protect against the disease.
Researchers from Duke University analyzed data from over 50,000 Fitbit users across four states and found that daylight saving time does not affect overall daily step counts. However, they did notice a shift in steps taken between morning and evening, likely due to adjustments made to match the new daylight availability.
The American Geriatrics Society (AGS) has selected 24 members for their outstanding commitment to advancing high-quality, person-centered care for older adults. These individuals have made meaningful contributions to the field of geriatrics through scholarship, advocacy, and clinical excellence.
A new study from Rice University transforms lunar regolith simulant into a valuable building resource, strengthening advanced composite materials by up to 30-40%. The innovative approach reduces dependence on Earth-supplied materials, increasing the feasibility of longer missions and infrastructure development.
A team from Oak Ridge National Laboratory used large-format additive manufacturing to create high-precision molds for advanced nuclear reactors, lowering costs and speeding deployment of new plants. The project demonstrates the potential of digital manufacturing to cut weeks off the schedule while meeting strict nuclear standards.
A USF study finds that children ages 9 to 12 engage with AR headsets in a more exploratory and intuitive way than adults, highlighting a mismatch between adult-designed systems and child-centered design. This difference has implications for educational applications of AR, which may require more flexible and creative interaction methods.
Researchers from the Salk Institute found that astrocytes play a crucial role in fragile X syndrome symptoms. Correcting dysregulations in star-shaped brain cells improved some symptoms, including reduced seizures and restored molecular balances in a mouse model of FXS. The study validates the importance of studying astrocytes in FXS r...
The study reveals how copper nitrite reductase converts nitrite to nitric oxide gas through an ordered sequence, clarifying electron, substrate, and proton coordination. The research demonstrates the potential of combining XFEL technology with advanced software for individual-atom resolution structures.
The new program addresses unique challenges faced by female athletes, including injury prevention, hormonal health, pelvic floor issues, and heart health. It offers coordinated care through a team of experts in orthopedic sports medicine, primary care, and other specialties.
Researchers at INRS have developed a photochemical synthesis strategy for metal-organic frameworks (MOFs), enabling precise control under ambient conditions. The approach significantly reduces energy consumption, leading to enhanced photocatalytic activity and improved structural precision.
Researchers at Stanford Medicine successfully cured Type 1 diabetes in mice by combining a blood stem cell and pancreatic islet cell transplant with a gentler pre-transplant treatment. The approach resulted in an immune system made up of cells from both the donor and recipient, preventing disease progression and cure.
A new targeted therapy has shown strong results in preclinical studies against aggressive childhood and adult cancers, eliminating tumours and stopping cancer spread. The therapy targets the IL1RAP protein, which is found on cancer cells but largely absent from normal tissues, allowing for precise delivery of treatment.
A new freeze-dried blood product called Thrombosomes has shown promise in treating traumatic brain injuries by reducing swelling and bleeding. The product, derived from platelets with trehalose preservation, has been tested on mice and found to be effective in stabilizing damaged blood vessels.
Researchers at the University of Nebraska-Lincoln have developed a promising new vaccine approach against highly pathogenic bird flu (H5N1) that demonstrates strong efficacy in both mice and dairy cattle. The vaccine platform protects against multiple H5N1 strains and generates immunity in both the bloodstream and respiratory tract.
Researchers at UCLA mapped how Down syndrome disrupts prenatal neuron development, leading to cognitive and sensory processing differences. The study found altered developmental sequences and cell populations that may contribute to the condition's effects.
A study of 3,000 Punjabi Sikhs identified new molecular pathways contributing to cardiovascular disease, including a link between lipid metabolites and immune cell signaling. These findings offer insights into diverse molecular origins of cardiometabolic disease and potential pathways for designing innovative therapies.
Researchers develop a new approach to selectively insert nitrogen into specific carbon-hydrogen bonds in organic molecules, enabling efficient and scalable synthesis of amines. This method simplifies the production of valuable chemicals used in pharmaceuticals, agrochemicals, and polymers.
Researchers at the University of Pennsylvania have designed a tiny robot that uses a knotted fiber to store energy, which is released when heated. The robot can leap meters into the air, flip mid-flight, and even plant seeds with high local pressure.
A new study found that the heart's constant beating may actively suppress tumor growth in cardiac tissues by altering gene regulation and reducing proliferation. This mechanical force also reshapes the cancer cell genome's regulatory landscape, influencing whether cells can proliferate.
A new study reveals that colossal octopuses were top predators in Cretaceous oceans, with species like Nanaimoteuthis jeletzkyi growing up to 19 meters in length. The discovery suggests these creatures played a significant role in shaping marine ecosystems, potentially preying upon large vertebrate apex predators.
New research has found that immature red blood cells can import heme from surrounding cells, overcoming long-standing assumptions about heme and red blood cells. This discovery could lead to new therapeutic approaches for inherited genetic blood disorders such as β-thalassemia.
Researchers found that people with severe obesity and heart failure have weakened heart muscles, which can be reversed through weight loss. The study identified a chemical change in a protein called troponin I as the underlying cause of this condition.
Researchers at Kyoto University discovered a previously unrecognized feature in near-fault seismic records of large earthquakes: a distinct stopping phase. This phase represents a systematic signal associated with the termination of rupture, demonstrating that many near-field recordings contain this coherent stopping phase.
New high-altitude measurements have revealed a hidden population of extremely small, organic-rich aerosol particles in the lower stratosphere. These ultrafine aerosols are found to dominate the surface area available for heterogeneous atmospheric chemistry and act as a significant condensation sink.
New research found that maintaining in-person work provided psychological benefits, while job loss and employment disruptions significantly increased depression risk. Older adults with stable employment experienced significant mental health benefits, particularly women who shouldered increased caregiving responsibilities.
Early octopuses were gigantic predators that hunted at the top of the food web, alongside large marine vertebrates. They had powerful jaws with extensive wear marks, indicating a strong biting force and aggressive feeding strategy.
A new paper in Neuroscience & Biobehavioural Review proposes a comprehensive neurobiological model of affective tactile memory, suggesting that emotionally meaningful touch is stored in the brain in powerful and lasting ways. This research opens a new window into how early and everyday tactile experiences influence our emotional lives.
Two-dimensional nanomaterials enhance M/NEMS sensors' mechanical strength, electrical conductivity, thermal stability, and biocompatibility. Their applications in biosensing and medical diagnostics show rapid response and high-sensitivity detection.
Researchers found that a dense piece of lithospheric mantle beneath the Hangay Mountains broke off and sank into the deeper mantle about 125-114 million years ago. This 'foundering' event triggered melting of the mantle, generated magma, and caused the overlying crust to dome upward.
A recent study reveals that men have lower fertility rates than women worldwide. The research attributes this shift to declining mortality rates, narrowing mortality gaps, and sex-selective abortions in some countries. As a result, the proportion of men in the population is increasing, presenting challenges for society.
Researchers at FAU are developing artificial muscles that can be controlled by light using tiny molecular machines. The technology enables the creation of intelligent materials with programmable properties, such as rigidity and elasticity under different wavelengths of light.
The article presents a conceptual design for an in-situ energy station on Mars, which could alleviate power fluctuations and distribution issues. The system utilizes the Martian atmosphere as a working medium for power generation and storage, with potential to save over 20 tons of payload in future manned missions.
A new UK study found that many heat-related deaths occur during lower-level alerts, highlighting widespread gaps in awareness and response. Older people are particularly vulnerable to these risks, with lower engagement with warnings leaving them exposed.
Researchers identified a new compound, Apilimod, that prevents hepatitis E virus infection by blocking a key cellular process, PIKfyve. This approach may offer a more effective treatment with lower risk of resistance development.
The EBRAINS Roadmap Symposium will bring together the global neuroscience community to shape the EBRAINS 10-Year-Roadmap. A total of 159 submissions from 134 unique contributors across 25 countries have been received, reflecting the momentum of Europe's digital neuroscience landscape.
A recent study published in Cell Reports identified a key pathway through which the hormone FGF21 influences eating behavior and energy balance. The findings highlight the importance of nutrition in brain function and suggest that FGF21-based therapies could be optimized to target specific brain circuits.
Researchers are close to building a 'virtual gut' capable of predicting responses to diet, drugs, and microbiome-based therapies. A new review outlines an analytical framework for host-microbiome multi-omics studies, covering preprocessing, feature selection, data integration, predictive modeling, and evaluation.
Researchers have made significant breakthroughs in prostate cancer treatment with new imaging techniques and targeted therapies, including a PSMA-targeting antibody and a CD44v6-targeting radiotherapy. These advancements aim to improve patient outcomes by tailoring diagnosis and treatment to individual needs.
Researchers review data-driven leakage diagnosis methods connecting single pipeline analysis with energy transmission systems, focusing on nonlinear mapping and spatiotemporal feature extraction. Advanced signal processing and multi-modal fusion techniques improve detection accuracy in complex scenarios.
A study led by Chinese Academy of Sciences reveals climate change leads to unprecedented sensitivity of soil inorganic carbon pools. Climate-driven effects on SIC dynamics are quantified using a novel process-based model, showing significant losses of up to 307 Tg C in topsoil.
A new study from the University of New Hampshire found that consumer trust in smart technologies like Alexa or Ring's video doorbells depends on a person's political beliefs. Conservatives tend to be more open to sharing their data, while liberals show more concern about privacy risks.
The study reveals that DUX family proteins undergo liquid-liquid phase separation to drive the transition to a totipotent-like state. This process is mediated by dynamic nuclear condensates, which act as specialized transcriptional hubs to activate totipotency-specific genes and retrotransposons.
The UFZ research team has developed a two-stage electrochemical purification process to efficiently degrade short-chain PFAS in water. This process uses electro-adsorption and electro-oxidation to concentrate and break down PFBA, resulting in easy separation of the fluoride by-product.
A new human cell model has been developed to realistically replicate the pathological processes of neurodegenerative dementias, such as Alzheimer's disease and frontotemporal dementia. The model exhibits tau aggregates and neuronal damage typical of these diseases, opening up prospects for drug development and therapy.
A new study from the University of Copenhagen shows that Danish retailers can generate a net financial gain of €0.3-€0.8 per kilo by selling surplus food at discounted prices. Donating food to organizations that redistribute it to vulnerable people is often cheaper than disposal, with savings of €0.10-€0.20 per kilo.
Human tumor organoids advance cancer modeling by preserving patient-specific characteristics and functional drug responses. The review highlights the need for quality control, cross-laboratory standardization, and ethical governance to enable broader real-world implementation.
A new measurement technique using nanomembranes and infrared light detects tiny amounts of substances in minutes, reducing sampling time by 100-fold. The technology analyzes particles accumulating on a tiny membrane, heating it up when certain wavelengths are absorbed.
Conventional models fail to capture human-relevant immune responses, hindering therapeutic translation. Immune-inclusive microphysiological platforms recapitulate inflammation, fibrosis, and immune-stromal crosstalk.
Researchers used high-throughput RNA sequencing to identify many more insect viruses in mosquitoes, some of which are globally distributed while others are unique to specific continents. By studying viral small RNAs, they can discover new viruses and understand how mosquitoes enable viral disease transmission.
Disrupted ecosystems can increase risk for food security, water scarcity, health and well-being, crime, mass migrations, border breaches, and social unrest. Governments must protect natural infrastructure to safeguard citizens' basic needs and prevent ecological disruptions.
The Bial Foundation is launching a new call for Grants for Scientific Research 2026/2027 in psychophysiology and parapsychology. The maximum grant amount is €60,000 per project, with applications open until 31 August 2026.
A new EU project study found that combined exposures to man-made chemicals can lead to measurable biological effects not explained by individual substances, underestimating overall risk. The research identified a continuous exposure pathway from environment to people, including breast milk and umbilical cord blood.
Researchers at Princeton University have developed a 3D device that combines living brain cells with advanced electronics to recognize patterns using computational techniques. The device creates a vast 3D network of neurons that can be used for computation, offering a potential solution to the energy bottleneck in modern AI technology.
A Rutgers Health-led survey found that 68% of people living with HIV prefer long-acting injections, but only 2.8% actually received them. The study identified factors limiting adoption, including pill burden, detectable viral load, and provider bias.
Citizen science projects are expanding globally to study bat ecology and support conservation. Methods include acoustic surveys and observations, providing valuable insights into bat distribution and seasonal activity. Collaboration with community members is crucial for advancing understanding of bat ecology and informing habitat prote...
The joint laboratory will leverage AI to enhance urban health assessments, integrate big data, and develop integrated governance solutions. The research will focus on six core areas, including national strategic priorities and technical bottlenecks in AI and digital twins.
An international team of physicists has achieved unprecedented accuracy in computing the magnetic properties of the muon using Jülich supercomputers. The result resolves long-standing uncertainty between theory and experiment, achieving a precision that reduces the uncertainty by a factor of 1.6.
Researchers propose an electron-bridge interface using n-type Zn-Al layered double hydroxide (AZH) to address interface failure in zinc anodes. This design enables simultaneous deposition of zinc at the interface and surface, enhancing the anode's adaptability to volume changes.
A new conversational AI tool uses trusted medical protocols to provide guidance on symptom assessment and triage, reducing unnecessary hospital visits. The system has been tested across over 30,000 simulated conversations with high accuracy, making it a promising support tool for healthcare organizations.
The TEAM platform successfully replaced Y chromosomes in mice, but human Y chromosomes showed poor stability due to centromere incompatibility. Centromere dysfunction drives chromosome instability and inflammatory disease phenotypes.
Researchers have mapped blood vessels in human adipose tissue with unprecedented detail, revealing that they are not only affected by disease but also play an active role in its processes. The study identifies unique cell types with mixed characteristics, suggesting a new approach to treating metabolic diseases.
The Hong Kong Global AI Governance Conference 2026 brought together scholars, policymakers, and industry practitioners to address emerging challenges in AI governance. Key discussions highlighted the need for global coordination and integration between technology and humanities.
Researchers at DTU have developed a new magnetic material that features a stable internal magnetic structure and almost no external magnetic field, above room temperature. This could enable faster components and lower energy consumption in spintronics.
A new empirical study found a direct link between climate finance and lower conflict risk in developing countries. Climate finance that alleviates water stress and boosts renewable energy projects contributes to peace and stability, with greater impact at higher levels of funding.
The CIRTESU at Universitat Jaume I develops an experimental modular robotic fish prototype for aquaculture, reducing fish stress. The UJIFISH-I platform demonstrates high manoeuvrability and reliable target detection accuracy in controlled tests.
A six-year study by HKUMed found robotic total hip replacement had a significantly lower reoperation rate of 0.6% within 90 days, compared to 2.5% with conventional procedures.
Researchers have developed a universal toolkit for editing bacterial DNA in 15 diverse species, including human pathogens and fast-growing biotechnology organisms. The technology uses retrons, an immune system that produces DNA, to efficiently modify genes, with varying success rates across different species.
New research on moiré patterns in ferroelectricity has revealed unusual electronic and optical effects, suggesting that these materials could play a crucial role in future low-energy nanoelectronics. The findings are promising for the development of high-performance computing technologies, such as brain-inspired computing systems.
Researchers from UNIGE have identified a molecular mechanism regulating cellular balance and found that TORC2's activation is controlled by a molecular 'cork'. This discovery paves the way for targeting this mechanism to treat diseases like cancer and diabetes.
A new study reveals a post-pandemic cycling boom in major cities, with fatality rates dropping by up to 88% in Paris, 82% in London, and 62% in New York City. The improvement is attributed to the expansion and improvement of cycling infrastructure, including cycleways separated from motor vehicle traffic.
Researchers elucidated S1P receptor ligand binding mechanisms to facilitate rational drug design. Allosteric and bitopic ligands reveal distinct binding sites with specific residues determining subtype selectivity.
A new study from the University of Lausanne identifies a specific subset of fibroblasts that produce Ccl19, an 'attractant signal' for cytotoxic T lymphocytes, bringing them into contact with type 1 dendritic cells. This mechanism is essential for proper immune cell organization and function.
A study found that leaf-cutter ants can provide ecological services to cocoa agroforests, reducing damage caused by the insects. By using simple methods like planting papayas as a 'distraction' and preserving surrounding forests, farmers can produce good cocoa while maintaining biodiversity
A team of scientists developed an AI-generated photonic (AIGP) framework that directly maps optical properties to subwavelength photonic structures using a latent diffusion model. The system achieves high-precision mapping, supports flexible design constraints, and possesses fuzzy search capability.
A study found international students in Japan had poorer health than Japanese peers due to lower health literacy. Health literacy was key to bridging the gap, with international students reporting better health status among those with higher literacy levels.
Researchers have analyzed a 380 million-year-old fossil fish skull using high-tech neutron imaging, finding similarities with modern fish brains. The study also uncovered adaptations for life near water's surface, including air intake openings and light detection organs.
A new study found comprehensive evidence that weight-loss GLP-1 receptor agonists like semaglutide reduce amyloid-beta and tau buildup in the brain. Consistent reductions were seen in animal and cell studies, with liraglutide showing the most positive effects.
Researchers have discovered that changes in African topography led to enhanced South Asian summer monsoon precipitation during the Early to Middle Miocene. This phenomenon was driven by altered atmospheric circulation patterns and moisture transport, resulting in increased convective activity and strengthening of the monsoon. The findi...
The study found a decline in age-standardized incidence rates for ischemic heart disease (IHD) in high-income countries, but a rapid rise in burden due to the increasing number of older adults and a growing global population. The total number of incident IHD cases is expected to continue rising until 2030.
Researchers found a significant increase in TAVR search volume and a decline in SAVR searches over the past decade, reflecting a shift towards minimally invasive therapies. The study also highlighted disparities in awareness across rural and low-volume treatment areas.
The Nordic-Baltic initiative aims to reduce greenhouse gas emissions in the European maritime sector by retrofitting existing vessels with alternative fuels and digital technologies. The alliance, involving Estonia, Finland, and Norway, aligns with EU climate and industrial policies, including the Fit for 55 package.
Researchers found strong evidence for supplements like beta-alanine, caffeine, carbohydrates, and creatine monohydrate to improve cycling performance. Supplements also support recovery, bone health, and immunity.
Researchers developed an AI method to automate charge transition line extraction from charge stability diagrams, enabling high-efficiency single-electron region definition and virtual gate configuration. This breakthrough aims to scale up quantum computing by handling vast numbers of qubits beyond human capability.
The thrush nightingale migrates up to 18,000 km with four-to-five consecutive nighttime flights and daytime breaks to avoid intense heat, conserving energy along the way. Advanced sensors track this extreme behaviour, providing insight into the bird's strategy for survival.
Researchers found that BRCA1 regulates innate immune signaling through IRF3, which is downregulated in BRCA1 deficient cells, leading to reduced drug sensitivity and PARPi resistance. Combining poly(I:C) with PARPi improves antitumor efficacy in vivo.
A new online platform enables non-experts to analyze complex OCT signals and generate realistic digital phantoms for optical cancer diagnostics. The platform's multimodal processing capabilities facilitate disease classification and tumor margin isolation.
Scientists discover that tRNA gene mutations can alter the reading of the genetic code, leading to increased protein synthesis errors. This phenomenon is linked to aging and cellular decline, with potential implications for neurodegenerative diseases like Alzheimer's.
A team led by Prof. Orna Amster-Choder will investigate rapid physical and chemical changes in bacterial cells to adapt to stress, challenging traditional assumptions about gene expression.
Neutron scattering reveals a new type of protein motion that depends on the surrounding environment within assemblies. The observed behaviour, known as non-Fickian diffusion, shows that molecular motion can no longer be described by a single uniform rule across the whole system.
Researchers will use DNA-encoded chemical libraries and artificial intelligence to screen hundreds of millions of potential drug compounds, identifying those most likely to succeed in treating Alzheimer's. The project aims to shorten the timeline for identifying new treatments, bringing them to patients faster and with greater precision.
A new study reveals that bacteria can actively limit the spread of antibiotic resistance genes by deploying molecular gatekeepers called YokF. This mechanism blocks the transfer of beneficial genes, giving microbes a competitive advantage in dense microbial communities.
Researchers found that black grouse can't see dark shades of red and have limited visual contrast, making certain colors ineffective at warning them away from fatal cables. To mitigate this risk, they recommend using large, strongly contrasting markers to provide enough time for the birds to react.
Researchers developed a sequential error-robust FISH spatial mapping platform to profile complex microbial communities at single-cell resolution. The platform enabled autonomous execution and revealed structured microbial clustering and species co-occurrence patterns.
A cross-sectional study of patients with de novo metastatic breast cancer found racial and ethnic disparities in disease presentation. De novo metastatic breast cancer disproportionately contributes to breast cancer mortality in the U.S., emphasizing the need for tailored interventions to improve care delivery and outcomes.
Tirzepatide significantly reduces cardiovascular risk in high-risk patients, including those undergoing percutaneous coronary intervention (PCI) and transcatheter aortic valve replacement (TAVR). The study found tirzepatide consistently reduced major adverse cardiovascular events and mortality across multiple time points.
A new study transforms apple pomace into valuable bioethanol and animal feed ingredients through SHF and SSF. The research highlights the potential of agro-industrial waste as a renewable energy source and nutritious food supplement.
A new analysis of a major clinical trial found that vitamin D supplementation reduced diabetes risk in prediabetic adults with certain variations in the vitamin D receptor gene. The study suggests personalized medical care could delay or prevent diabetes onset for millions of Americans living with prediabetes.
Muscle size, strength, and performance can be improved without exhausting exercises. Eccentric exercises, which involve lengthening muscles during movement, generate more force with less energy than traditional exercises.
A cross-sectional study found no association between longer breastfeeding duration and cognitive performance in unadjusted models, however, a positive correlation emerged after controlling for socioeconomic factors. Longer breastfeeding durations were more common among low-income families, highlighting the need for continued support.
Researchers at the University of Melbourne have uncovered the formation process of the Twelve Apostles, revealing that tectonic plate movements lifted and tilted the giant structures out of the sea. The study found that the Apostle's age is actually younger than previously thought, with layers dating back to 8.6-14 million years.
A cross-sectional study found intestinal Candida albicans abundance correlates with subclinical coronary atherosclerosis in metabolic dysfunction-associated steatotic liver disease. Cirrhosis patients showed higher Candida albicans levels and more severe atherosclerosis.
Hyperbaric oxygen therapy (HBOT) exhibits dual effects in glioblastoma management, enhancing radiosensitivity and chemotherapy efficacy while promoting tumor progression. HBOT normalizes the tumor microenvironment via vessel normalization and immune cell modulation, attenuating cancer stem cell properties.
A recent study has found that epigenetic clocks are associated with cognitive impairment and dementia, but only specific epigenetic markers related to smoking exposure are linked to neurodegenerative changes. The study suggests that measures of epigenetic age acceleration capture different aspects of biological aging.
Researchers at NTNU have developed a model that calculates which high-speed passenger routes can be operated with zero-emission express ferries. The study shows that a combination of batteries and fuel cells is necessary to meet the goal, emphasizing the importance of smart energy management.
Transcatheter arterialization of the deep veins (TADV) significantly improves quality of life in patients with severe CLTI, reducing concerns about poor circulation and daily activities. Six months post-procedure, patients showed a 50% reduction in circulation concerns, improved sleep patterns, and reduced foot wound symptoms.
A new transcatheter mitral valve replacement (TMVR) procedure has shown significant benefits for patients with severe mitral regurgitation, reducing symptoms and improving quality of life. The study found that the treatment sustained clinical improvements over one year, with no major complications.
Researchers found that patients with single-vessel runoff maintained excellent patency through three years, and could safely benefit from minimally invasive treatment. The study results showed no significant difference in outcomes for patients with one or more vessels running blood to the lower leg.
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 32% of the US adult population. Obesity was identified as the strongest independent MRF among Asians, Whites, and Hispanics, particularly in individuals younger than 50 years, whereas hypertension was the strongest independent MRF in Blacks.
A new sub-study suggests that using a sirolimus-eluting balloon can reduce the number of stents needed, making it a safe and effective way to treat certain heart attacks or unstable chest pain. At one year, the rates of target vessel failure and cardiac death were low and similar between the two groups.
A registry analysis found that while men and women with acute myocardial infarction-related cardiogenic shock differ in treatment options, clinical decisions are driven by objective markers of illness severity rather than sex. The study suggests significant differences in how treatment options are discussed with patients and caregivers.
The CERAMICS registry found that most patients survived hospital discharge, with 71% overall survival and 60% of those in the most severe stage E shock. Early use of a small heart pump improves outcomes in patients experiencing cardiogenic shock after a heart attack and stenting procedure.
A recent study found that people with higher isoflavone consumption experienced fewer breathing-related symptoms and improved lung health. Isoflavones, commonly found in legumes and soy-based foods, may play a key role in reducing COPD symptoms.
SourceCOPD Foundation·JournalChronic Obstructive Pulmonary Diseases Journal of the COPD Foundation·TypeObservational study·DateApr 23, 2026
The Keck School of Medicine of USC and Tempus are creating a system-wide framework to integrate clinical care, clinical trials, and research through AI-powered precision medicine tools. The goal is to enhance patient care and accelerate research and innovation.
A national study found that people with severe strokes have a five times higher odds of developing dementia. Stroke severity also affects thinking and memory after stroke, highlighting the need for close monitoring and treatment of dementia risk factors.
A study mapped early molecular and cellular changes in the jaw joint that may trigger temporomandibular joint osteoarthritis. The research found structural and molecular changes in joint tissues, including inflammation, fibrosis, and metabolic shifts. Single-cell sequencing revealed diverse cell populations interacting within the synov...
A UC San Diego study found that diabetes is associated with changes in biological signals in the blood linked to Alzheimer's disease and brain damage in Latino adults. Researchers suggest that metabolic health may play a role in shaping future dementia risk.
The study found that the Turkana Rift has been significantly thinned, with the crust about 13 kilometers thick, compared to over 35 kilometers farther from the rift. This thinning is a sign of a process called 'necking' where the crust stretches and becomes weaker, promoting continued rifting.
Researchers developed nanoribbons with tailored electronic properties, enabling flexible electronics, ultra-small circuits and more efficient solar cells. The discovery paves the way for unprecedented control in next-generation technologies.
Researchers discovered a massive magma intrusion on São Jorge Island in the Azores, which stalled just 1.6km below the surface, avoiding an eruption. The study used seismometers and satellite data to reconstruct the underground movement of magma, revealing how it rose through a main fault system.
Researchers have identified a single genetic change that drives the development of myeloid leukaemia in children with Down Syndrome. The study reveals a common vulnerability and treatment target, suggesting potential repurposed treatments. The genetic change, related to the GATA1 gene, is present at all stages of the disease.
A new American Heart Association scientific statement recommends that children and adolescents with certain heart conditions participate in physical activities after a detailed individualized risk assessment. Light-to-moderate intensity exercise may be suitable to maintain physical fitness and quality of life, while structured physical...
Scientists have mapped the structure of Vibrio bacteria with unprecedented detail, revealing a new target for treatment. The findings could provide a solution to life-threatening infections linked to antibiotic resistance.
Researchers discovered a specific type of water in interstellar comet 3I/ATLAS that contains deuterium, revealing it came from a colder environment. This finding suggests the conditions that led to our solar system's formation are not ubiquitous throughout space.
Researchers at McMaster University developed a new generative AI model that designed a brand-new antibiotic in early tests, drastically speeding up drug discovery. The model generated structurally novel antibiotic candidates from a vast chemical space of 46 billion possible compounds.
A study published in Scientific Reports reveals a connection between ADHD-related traits and chronic pain, highlighting the importance of addressing ADHD in pain management. The research suggests that treating ADHD may help reduce chronic pain severity.
Researchers investigate whether micro- and nanoplastics contribute to liver disease through oxidative stress, fibrogenesis, and inflammation. They emphasize the need for increased research into plastic-induced liver injury and its potential impact on human health.
A study finds that rectal cancer mortality is increasing rapidly among adults under 45, with Hispanic and Western US populations experiencing the steepest rises. The study calls for earlier screening and increased awareness to combat this growing trend.
Researchers at NYU Langone Health found that high levels of a toxic molecule in the gut may trigger lupus nephritis. The study suggests using antibiotics as an alternative treatment instead of immunosuppressants.
Dr. Kwak's research proposes a new paradigm for robots in everyday environments, integrating perception and cognition capabilities into objects and spaces. Her work has led to practical implementations, such as educational robots and smart furniture, demonstrating the potential for human-centered robot design.
Researchers found that restoring a young microbiome can reverse features of aging in the liver, including inflammation and DNA damage. The study suggests that a healthy gut microbiome plays a key role in preventing liver cancer.
A new study suggests that eating late at night can disrupt bowel function and lead to constipation and diarrhea. Individuals who experienced high levels of chronic stress and ate more than 25% of daily calories after 9pm were more likely to report bowel problems, highlighting the impact of meal timing on gut health.
A new procedure, duodenal mucosal resurfacing, has shown promising results in preventing weight regain after GLP-1 therapy discontinuation. The study found that patients who underwent the procedure maintained over 80% of their weight loss and regained less weight compared to those who received a sham procedure.