Researchers developed a new treatment for acute myeloid leukemia (AML) by using AcTor, a molecule that inhibits a signalling protein, in combination with ixazomib. The treatment successfully eliminated cancer cells and leukemic stem cells, showing promising results in mice studies.
Researchers at the University of Gothenburg identified a link between specific gut bacteria activities and primary sclerosing cholangitis, a rare chronic liver disease. Elevated levels of the metabolite ImP, formed by gut bacteria breakdown, can predict poorer survival outcomes and induce liver inflammation in PSC patients.
A new clinical decision support tool, FRACTURE-ML, identifies people at high hip fracture risk using existing health registers and avoids patient-reported information. It has the potential to become an important tool for preventive care, potentially identifying nearly seven times as many people at risk of hip fracture.
A Swedish study published in JAMA Network Open reveals that patients treated with finasteride for benign prostatic hyperplasia experienced fewer serious complications after an acute heart attack. The risk of serious complications was 20.8% among those treated with finasteride, compared to 24.3% among matched controls.
A Swedish population-level study found that individuals with a comprehensive understanding of palliative care are more likely to prefer end-of-life care at home or in a hospice. The study also highlights the importance of earlier palliative care initiation to alleviate suffering and promote well-being.
Researchers analyzed blood samples from 949 people over 50 in Nigeria and found unique protein profiles compared to a comparable group in Canada. The study suggests the need for globally applicable biomarkers to avoid misdiagnosis due to varying risk factors and environmental exposures across populations.
Recent studies from the University of Gothenburg found that nicotine use is associated with symptoms of anxiety, depression, and other mental health problems in adolescents. Girls are particularly vulnerable to these effects, including increased risk of worsening sleep problems, low mood, and difficulties concentrating.
Researchers identified seven proteins in the blood that can help diagnose Alzheimer's disease more accurately, improving treatment choices and future research. The new blood-based tests provide a clearer picture of the disease, allowing for earlier detection and better patient outcomes.
A new review suggests that continuous glucose monitoring technology offers no scientific evidence of improved health outcomes in people without diabetes. However, it may be beneficial for those with type 2 diabetes by reducing HbA1c levels and minimizing finger-stick tests.
Researchers tested cortisone eye drops to slow ROP progression in 100 premature babies. The intervention reduced treatment-requiring ROP by 47% compared to placebo.
Genital herpes is a viral infection that establishes a lifelong infection by entering nerve cells and can be relieved with medication. Researchers have identified glycoprotein G as a promising target for a future vaccine, which could provide protection against HSV-2 spread to the nervous system.
A recent study published in Nature Communications has identified a clear link between the composition of gut bacteria and frailty in older women. The research found that lower gut bacterial diversity and impaired function are associated with increased vulnerability to disease, falls, functional impairment, and death.
A study from the University of Gothenburg found that patients with chronic pain do not have equal access to specialized rehabilitation programs. Sociodemographic factors such as education, age, sex, and region of birth play a significant role in determining participation rates. The study suggests that addressing these disparities is cr...
A new robot mimics the movement of an inchworm using a soft muscle-like material, allowing it to navigate challenging environments. The robot can be used to inspect sewer pipes or explore the planet Mars without multiple actuators.
The Crown Princess Victoria Professorship in Biodiversity at the University of Gothenburg aims to strengthen interdisciplinary research into biodiversity and develop innovative strategies for its conservation. Alexandre Antonelli, a leading researcher, has been appointed to lead this initiative.
Researchers developed an AI system called SmartTrap that uses optical tweezers to capture particles, take measurements, and load new samples autonomously. This technology accelerates the analysis of life's smallest components, potentially transforming laboratories in the near future.
Persons with diabetes are at higher risk of periodontitis, tooth loss, and peri-implantitis. Poor blood sugar control exacerbates these risks, highlighting the importance of close collaboration between healthcare and dental care providers.
Researchers at the University of Gothenburg found that horses in a children's zoo showed no significant increase in heart rate when petted by children, despite other sounds like barking dogs having no effect. However, they did exhibit increased stress when exposed to noise from an excavator.
Research from the University of Gothenburg has found that spring storms in Europe are becoming more common, with a shift towards more intense and frequent winter storms. The study, which analyzed historical weather data from 1940 to 2024, suggests that Arctic sea ice reduction is a key factor contributing to these changes.
Studies in Sweden, Finland, and Denmark show that dirty waste disposal rooms evoke feelings of disgust, increasing the risk of incorrect waste disposal. Clean environments, on the other hand, lead to a decrease in littering.
A recent study by University of Gothenburg researchers found that antibiotics for uncomplicated acute sore throats have minimal preventive effect against serious streptococcal infections. Early recognition of warning signs is crucial, and a vaccine is being awaited as a long-term solution.
Weight loss after bariatric surgery is associated with better ability to cope with daily household tasks such as cleaning and grocery shopping. The study also found that maintaining weight loss for long periods results in improved functionality and independence. Patients who regained lost weight experienced poorer outcomes over time.
A new study published in The Quarterly Journal of Economics reveals that a good manager's leadership ability is roughly as important for team performance as the total productive capacity of employees. Economic decision-making and skills are key indicators of successful management.
Two new international studies found that healthy lifestyles can have a protective effect on childhood cancer survivors, reducing the risk of chronic health problems. The studies suggest that physical activity, a healthy weight, and other lifestyle factors can significantly reduce the burden of disease in adulthood.
A recent study of over 1,800 infants in Sweden found that most young children have sufficient vitamin D levels, but intake was too low for some. The research also explored the climate impact of foods providing vitamin D, concluding that plant-based alternatives are a climate-friendly source.
Two studies suggest that weight loss after bariatric surgery reduces cancer risk in women, with insulin levels and genetic background playing key roles. Women carrying a specific FTO genetic variant showed significant breast cancer risk reduction.
Research finds gestational diabetes significantly increases risk of type 2 diabetes in women with normal pre-pregnancy weight. The study, published in eClinicalMedicine, analyzed over 1.15 million Swedish mothers and found elevated blood sugar levels predict future type 2 diabetes.
Researchers found that shrouding blankets increase dignity for parents who lose a child, offering a tangible way to cope with grief. The blankets provide comfort and stability, allowing parents to hold their child without feeling overwhelmed.
A study by the University of Gothenburg reveals that changes in gut bacteria composition after bariatric surgery are strongly associated with improved glucose metabolism and insulin release. Patients with type 2 diabetes who achieved improved glycemic control exhibited greater microbial gene richness and enhanced fermentation processes.
Researchers identified ten previously unknown symptoms strongly associated with eclampsia, including twitching and impaired speech. These symptoms were rare among women without seizures but frequently occurred before an episode, increasing the risk of seizures.
A nationwide Swedish study of 27,789 individuals with confirmed celiac disease found no link between antibiotic use and increased risk of developing the autoimmune disorder. The study also revealed a higher proportion of prior antibiotics used among those with normal mucosa, suggesting other factors may contribute to its development.
Researchers found memory cells in nasal tissue can reactivate to fight influenza, reducing viral replication and protection against more severe illness. These immune cells can be used to develop better nasal vaccines.
Researchers found a distinct pattern of immune activation early in infection among individuals who later developed broadly neutralizing antibodies, suggesting interactions between the immune system and other infections may be linked to HIV response.
A new laser method allows researchers to study radioactive elements like neptunium and fermium, which have rugby ball-shaped atomic nuclei. The technique provides crucial information about the size and shape of atomic nuclei, essential for understanding actinide properties.
A study found that AI models trained on large amounts of registry data can identify individuals at higher risk of melanoma. The most advanced model distinguished individuals with a 33% probability of developing melanoma in about 73% of cases.
Researchers discovered that common human painkillers, such as aspirin and lidocaine, prevent Norway lobsters from exhibiting painful responses to electric shocks. This finding highlights the need for more humane methods of killing crustaceans, which may be phased out in favor of gentler alternatives.
A study by researchers at the University of Gothenburg found that children born before 24 weeks of gestation incur significant societal costs, peaking in the first year of life. The need for support persists long after initial care, with severe complications often leading to more extensive and long-term support needs.
A study by researchers at the University of Gothenburg finds that wildfires pose an ever-increasing threat to biodiversity, with nearly 84% of vulnerable species facing a higher risk by the end of this century. Climate action can reduce the occurrence of wildfires and mitigate the risks to species worldwide.
A higher testosterone level does not always indicate well-being in men, according to a study at the University of Gothenburg. Muscle health and inflammation are linked to testosterone levels, but symptoms like fatigue and depression have weaker connections.
The University of Gothenburg has secured funding to preserve Lennart Nilsson's archive, containing a life's work that transformed how we understand the human body, science, and photography in society. The archive will be made accessible for research and the public by 2029.
A systematic review found consistent evidence that snus causes gum recession, particularly with loose snus. White snus has virtually no studies on its long-term oral health effects, creating a significant knowledge gap.
The report highlights three major trends in democratic backsliding: democratic backsliding in stable democracies, reversals in democratized countries, and deepening autocracy in existing autocracies. Freedom of Expression and liberal aspects of democracy show the most drastic declines globally.
Researchers at the University of Gothenburg have identified a protein, ATF4, linked to increased metastasis and recurrence in lung cancer. The study reveals that older individuals' tumors are smaller and grow more slowly, yet more likely to have spread when detected.
Researchers at the University of Gothenburg measured carbon dioxide and oxygen levels in 23 mangrove areas, revealing global patterns in environmental stress. The study found that extreme conditions, including low oxygen and high carbon dioxide levels, are becoming more frequent and severe, posing a threat to sensitive fish species.
Research by Per Martinsson finds that frequent phone scrolling during breaks impairs relationships and perceptions of the work environment. The study, based on 25 interviews and 1,700 survey respondents, shows a negative association between phubbing and poorer work environments.
A study by the University of Gothenburg found that young adults are more likely to consume healthcare through online apps, especially when no patient fees are charged. Women tend to have higher consultation rates than men, who experience a sharper decline in consultations once they turn 20.
Researchers have discovered six Bronze Age mining sites in southwestern Spain, revealing extensive metal extraction and trade networks. The findings provide a concrete archaeological context for previous studies on the origin of Scandinavian Bronze.
Researchers at the University of Gothenburg have found that tirzepatide, the active ingredient in Mounjaro, reduces voluntary alcohol consumption by more than half in animals. The study also shows that the drug prevents relapse-like drinking and decreases drinking levels after a period without alcohol.
A recent study found that climate attitudes did not change in response to Hurricane Helene, suggesting that public perception of climate change is stable. The researchers also discovered that political affiliation was a stronger predictor of voting intentions than exposure to the hurricane.
Researchers have developed stable boron-fluorine compounds that enable the modification of complex molecules without breaking down medicines. These new compounds make it possible to increase the effect or reduce side effects of drugs at a late stage, reducing waste and improving resource efficiency.