By focusing on the specific regions of antibodies responsible for recognizing disease targets, the AI model improved binding affinity prediction and required fewer computational resources. This approach is similar to human-language AI models, where smaller domain-specific models trained on high-quality data can outperform larger ones.
A new study reveals that animals and microorganisms work together to break down microbial PHAs, providing a previously overlooked way for animal food webs to access carbon. This discovery opens a new perspective on interactions between microorganisms and animals, highlighting the importance of studying unusual organisms.
Researchers from Utrecht University found that the Atlantic Meridional Overturning Circulation's (AMOC) stability depends on how fast the climate is changing. Slow warming allows the ocean to adapt, while fast warming triggers a collapse around +2°C of warming.
Researchers developed a platform to screen nearly all human genome genes, linking disruption of individual genes to improved genetic outcomes in human cells. The top two genes, GJB2 and BET1L, were found to improve editing efficiency by more than six times when knocked out.
A study published in Nature Communications identified a language-specific brain network that can be detected even when the person is at rest or performing a task unrelated to language. The researchers used data from over 1,900 fMRI scans and found that this network spans the left hemisphere frontal and temporal regions of the brain.
A study reveals that environmental responsibility boosts corporate financial performance by increasing sales, especially for large companies after COVID-19. Stronger environmental performance generates higher sales leading to improved returns on assets and equity.
A team of researchers from Institute of Science Tokyo has developed a novel, one-step synthesis method for producing highly active nickel-cerium oxide catalysts. These catalysts achieve outstanding methanation performance while being suitable for large-scale production, offering a practical route toward carbon-neutral fuel technologies.
A coral-inspired 3D-printed scaffold reprograms immune cells to promote angiogenesis and bone regeneration, shifting macrophages from inflammatory M1 state to reparative M2 state. The scaffold also enhances angiogenesis, new bone formation, and reconstruction of bone defects.
Liver injuries from xenobiotics increased by nearly 400% between 2000 and 2024, with acetaminophen being the top driver. More than 80% of cases required inpatient care, highlighting the importance of poison centers in toxico-surveillance.
Researchers at Graz University of Technology developed design guidelines for batteries in electric vehicles to increase safety, make repairs easier, and improve sustainability. The new designs facilitate recycling and reuse of damaged cells, reducing waste and conserving resources.
A novel robot, BioflexBot, successfully mimics fundamental hand motions and exceeds human performance in precision and range of mobility. The BioflexBot can grasp complex objects, reach long distances, and deliver objects in confined spaces.
A new study provides compelling evidence that cynodonts, an ancestor of true mammals, may have been viviparous, giving birth to live young. The discovery sheds light on the reproductive mode of early mammalian ancestors and raises questions about other evolutionary traits.
Researchers at Osaka Metropolitan University found that a mitochondrial fusion protein called OPA1 plays a crucial role in regulating appetite and body weight. Mice lacking this protein exhibited increased food intake and age-related weight gain, highlighting the importance of OPA1 in maintaining energy metabolism.