AflHapX is critical for A. flavus's adaptive response to iron excess and starvation, influencing aflatoxin B1 production. The transcription factor regulates genes involved in iron homeostasis, aflatoxin biosynthesis, and oxidative stress responses.
Dr. Sophie de Vries receives funding to study how plants balance immunity with cooperation, while Dr. Tristan Stöber works on developing AI systems that can build accurate internal models of the world. Professor Elisa Oberbeckmann investigates gene regulation mechanisms.
The GSA opposes the significant reductions to Bears Ears and Grand Staircase–Escalante National Monuments, which preserve exceptional records of Earth history and support ongoing scientific discoveries. The organization calls for the restoration of boundaries and long-term stewardship of these irreplaceable landscapes.
UVic researchers played a significant role in Canada's Changing Climate Report 2026, providing detailed assessments of past and future climate changes in Canada. The report finds that human-caused greenhouse gas emissions are driving widespread changes, including extreme heat, warming oceans, and rising sea levels.
Researchers at the University of Arizona assessed seven generative AI models for fallibility, persuadability and correctability during lengthy conversations. The study revealed intrinsic limitations of these models, including oscillation between accepting and rejecting false statements, and the need for careful human engagement to miti...
The UN University's latest publication highlights the need for domain-informed AI in grid planning to address physical and fiscal risks from outdated climate data. The authors warn that 15-20 year lifespans of electricity infrastructure are based on historical weather records unlikely to hold in the coming decades.
Scientists have developed a method to identify where Earth's biggest earthquakes are most likely to occur, focusing on subduction zones. The approach uses GPS measurements to detect locked regions along faults, which store energy until a major earthquake triggers. While the method cannot predict tsunami size or timing, it can narrow do...
Scientists have discovered 10 new species of branching marine worms, shedding light on their evolution and diversity. The study, published in the Zoological Journal of the Linnean Society, used DNA sequencing and anatomical analyses to solve a long-standing puzzle and provide new insights into the evolution of complex body forms.
The study introduces a new bamboo fiber foam that combines electromagnetic shielding, flame retardancy, thermal insulation, and electrically driven heating in one lightweight material. The foam was created using ambient drying, which reduces energy consumption compared to traditional processing methods.
A four-year study in Heidelberg University found that a behavioral therapy-based program was 50% more effective than media education in preventing gaming disorder and problematic online behaviors in high-risk adolescents. The program achieved better results among participants at high risk of addiction.
Microplastics act as pollutant shuttles, carrying chemicals, pathogens and antibiotic resistance genes through water, soil, food webs and environmental boundaries. A three-tiered framework identifies conditions for dominant ecological risks, highlighting the need for realistic risk assessment and unified global governance.
A new review suggests slow pyrolysis can reduce environmental risks while recovering materials, metals, and energy from contaminated agricultural biomass. The process involves controlled heating, producing biochar, bio-oil, and gases, with potential applications in soil amendment, water treatment, and metal recovery.
Researchers discovered a bacterium in urine that can convert DHEA into testosterone, shedding light on a previously unknown microbial route to a hormone central to prostate biology. This finding raises new questions about the potential role of microorganisms near the prostate in shaping its chemical environment.
A statewide evaluation will assess the implementation and impact of California's traditional health care practices benefit, covering culturally grounded healing approaches for substance use disorders. The project aims to identify best practices for strengthening access to traditional healing and improving care for Native communities.
Researchers used satellite-observed chlorophyll fluorescence to detect subtle physiological changes in evergreen trees, revealing forest stress two years before bark beetle mortality appears. The technology could provide early warning for forest managers to prepare before mortality becomes widespread, helping to mitigate climate change...
Expectant mothers in the Philippines used creative coping strategies to manage sociopolitical stressors, including reframing difficult circumstances and maintaining a positive outlook. The study suggests that how new moms cope with stressful news may be more important than the news itself, with 67% of participants citing financial stre...
Dr. Amir Iravani brings expertise in molecular imaging and radiopharmaceutical therapy to UCLA Health, expanding research and clinical cancer care. He aims to integrate theranostics into cancer care, expand clinical trials, and develop new treatments for solid tumors and hematologic malignancies.
New research from Texas A&M University suggests that younger brains may be more vulnerable to post-traumatic epilepsy after traumatic brain injury, despite their flexibility to adapt. Older brains showed fewer signs of epilepsy but were vulnerable to neuroinflammation, circuit remodeling, and memory loss.
The Gerontological Society of America supports the 2026-27 respiratory season vaccine evidence review, highlighting the importance of evidence-based immunization recommendations across the life course. Vaccinations continue to provide meaningful protection against severe illness, hospitalization, and death for individuals of all ages.
A new white paper by Dr. Contessa T. Walker-Jackson suggests that teacher recognition should be specific, consistent, and connected to teachers' actual work. The paper recommends five leadership practices for school leaders to make recognition part of everyday practice, which can support teacher morale and engagement.
The employment-to-population ratio for people with disabilities increased from 38.3% to 39.8% in August 2026, a new all-time high. This uptick is attributed to more job seekers finding employment, despite rising cost-of-living prices affecting people with disabilities living at or below the poverty line.
A new study by the University of Vienna reveals that ammonia-oxidizing archaea in marine sponges are not strict specialists, but instead use amino acids such as valine, leucine, and isoleucine as additional food sources. This finding suggests that these symbiotic microbes may have an unknown ability to communicate with their animal hosts.
A new study found that inducing mitochondrial reactive oxygen species (ROS) during embryonic development protects the adult heart from chemotherapy toxicity in mice. The study discovered that stressed mitochondria release citrate, leading to long-term epigenetic changes that promote beneficial mitohormetic adaptations. These findings s...
SUNY Cobleskill Ag & Tech is developing a virtual reality course in agricultural engineering to provide rural farmers with hands-on training. The grant aims to give farmers technical skills without leaving their land, reducing costs and improving productivity.
Researchers found that energy-demanding tissues have larger macrophage crews to manage waste, with the number of macrophages tracking mitochondrial activity and waste production. This system is critical for tissue health and function, and may help preserve tissue function as we age.
Carbon did not migrate into the core, resulting in a graphite crust; silicon and sulphur are responsible for the core's low density. The graphite crust is approximately 40-120 meters thick and is composed of 1-3% carbon.
A UC3M study analyzes the regulations and complex logistics of animal spectacles in Roman amphitheaters, including the use of imperial constitutions and specialized units to track and transport wild beasts. The research reveals the logistical and economic challenges of these spectacles and the imperial power exercised over exotic animals.
A new study concludes that periodical cicadas could be heading toward extinction due to the historical loss of old-growth forests, which are their sole food source. The insects are unable to adapt to new habitats, making it unlikely for them to recolonize restored forests.
Researchers propose a new therapeutic perspective for pancreatic cancer, viewing radiotherapy as a tool capable of modulating the immune system and enhancing immunotherapy. The review highlights promising approaches currently being evaluated, including targeted radiotherapy and combination with next-generation immunotherapies.
Researchers at Lund University have developed a new type of LED light that controls light generation, reducing losses and increasing efficiency. The technology has the potential to lead to more energy-efficient light sources and advanced optoelectronic applications.
Researchers have demonstrated that superconductivity in magic-angle graphene can be completely suppressed by screening interactions between electrons. Increasing the carrier density in a neighbouring graphene bilayer progressively weakens superconductivity, with complete suppression at high carrier densities.
Oxidative stress drives destruction of nerve cells by disrupting energy-generating machinery, triggering chronic inflammation, and forming abnormal protein clumps. The review separates shared mechanisms from disease-specific pathways, highlighting the need for targeted treatments.
Emergency visits by children with suicide-related crises increased by 74% in hospitals with lower pediatric volume, often lacking specialized resources. These EDs often struggle to provide timely, effective, and equitable care to children in mental health crises.
The International Society of Microbiota has partnered with the Global Grants for Gut Health program to expand funding opportunities for Japanese early-career researchers. The new partnership will bring $100,000 in funding to Tokyo, highlighting the global significance of microbiome research in Japan.
A new paper outlines strategies to strengthen primary care pipeline in medical education, including mitigating administrative burdens, leveraging AI, and enriching student experiences. The authors emphasize the need for well-thought-out approaches to nudge the trend in a positive direction, rather than a single fix.
A study found that feeding and watching birds positively impacts people's well-being, reducing stress and increasing feelings of joy, gratitude, and calm. The activity also fosters engagement and a sense of meaning, as participants feel they are connecting with nature and contributing to science.
Researchers developed an AI tool, AIMe, to predict and organize small molecule structures, covering over 100 million compounds. The tool, called DeepMS2Reasoner, uses neuro-symbolic AI to simulate molecule fragmentation, providing interpretable outputs and accelerating hypothesis generation.
A study involving 48 preschool children found that brief digital or traditional gameplay improved performance on tasks requiring quick responses, but reduced performance on tasks demanding greater concentration and self-control. The study suggests that these play sessions temporarily enhance automatic attentional processes at the expen...
A new study found that US children's emergency visits for mental health crises increased by 74% between 2016 and 2022. Half of these visits occurred in hospitals with low pediatric volume, highlighting the need for specialized resources and training.
Researchers developed a cost-effective method to enhance the strength and thermal stability of 3D printing resins using modified mineral acicular wollastonite. The modified resin showed better thermal stability and reduced curing shrinkage, improving dimensional accuracy of printed parts.
Researchers developed multivalent mRNA-exosome vaccines that induce local inflammation, recruiting immune cells and triggering epigenetic regulation, turning 'cold' tumors into 'hot' niches. These vaccines drive tumor cell death and sensitize tumors to immune checkpoint inhibitors.
Researchers have developed a new material called davyne that changes color in the near-infrared region, invisible to the human eye, which could be used as an anti-counterfeit tag in banknotes and passports. The material's color-changing mechanism is similar to hackmanite, and its near-infrared activity can be switched on and off.
Researchers developed a mechanism-data fusion framework for rapid prediction and optimization of microstructure evolution in laser directed energy deposition of Ti-6Al-4V. The framework uses dual-level long short-term memory networks and multiscale physical modeling, achieving high accuracy and reducing computational cost.
A new study estimates that Parkinson's disease could cause a cumulative macroeconomic loss of CNY 473 billion between 2020 and 2040. The disease affects China's economy by reducing labor force participation, productivity, and investment in education and infrastructure.
The LIPLEG study found that liposuction is significantly superior to conservative therapy in terms of key treatment outcomes, with 68.3% of patients experiencing clinically relevant pain reduction. The procedure also led to a marked improvement in quality of life, with patients reporting a reduction in pain and an increase in mobility.
Researchers have compiled a comprehensive updated checklist of terrestrial mammals on Hainan Island, China's largest tropical island. The study documents 95 species, including 12.91% of China's terrestrial mammalian species richness, and identifies 10 species as threatened under IUCN criteria.
Researchers compared Bi-2212 and Nb3Al under identical room-temperature electron irradiation, revealing a significant difference in their responses to damage. Bi-2212 progressively lost its crystalline order and became fully amorphous, while Nb3Al retained its crystal structure even after a substantially longer exposure. The study prov...
A new study from the University of Bath warns that over-reliance on generative AI may weaken managers' ability to build moral insights, contextual understanding, and practical know-how. The research suggests that AI can strengthen managerial judgement when used as a tool for reflection, rather than a replacement for thinking.
A new study demonstrates TanSat-2's ability to distinguish between human carbon emissions and ecosystem carbon sinks. The satellite's observations of CO2 and chlorophyll fluorescence can simultaneously constrain net primary productivity and fossil fuel combustion emissions, leading to significant error reductions.
A new ERC-funded project at Aarhus University aims to investigate how hormones, stress, and genetic factors influence women's coronary arteries. The project will develop new models to explain why certain cardiovascular diseases affect women differently from men, and may lead to personalized rupture-risk maps and improved diagnosis and ...
Researchers developed a novel β-Ga2O3 photo-synapse that uses self-trapped holes to achieve improved stability and performance. The device exhibited excellent short-term and long-term plasticity, outperforming previous devices, and was integrated into neuromorphic machine vision systems for diversified in-sensor computing tasks.
This prospective multicenter study found obinutuzumab plus bendamustine to be highly effective in treating newly diagnosed indolent B-cell lymphoma in Chinese patients, with high response rates and manageable safety profile. Notably, the complete response rate was higher than reported in comparable Western studies, suggesting Chinese p...
Researchers found that Miracinonyx trumani preyed almost exclusively on fish, challenging the long-held assumption that it was a fast-running prey-chaser like modern cheetahs. The species shared a common ancestor with modern cheetahs about 4.7 million years ago, but diverged from a common ancestor with pumas about 2.6 million years ago.
A new study by UC Santa Cruz scientists has discovered that the extinct North American cat, Miracinonyx trumani, was not a true cheetah but a highly adaptable relative of the puma that specialized in eating fish to survive in the Arctic. The species' unique genetic blueprints allowed it to thrive in extreme environments, but its low ge...
Researchers create powerful optical device with layered semiconductor and metasurface, enhancing nonlinear frequency conversion and enabling efficient light mixing and transformation. The device has potential applications in telecommunications, quantum communication, and photonic quantum computing.
A Virginia study led by George Mason University professor Alison Cuellar found that both forms of Medicaid paid substantially less than Medicare Advantage, employer-sponsored, and marketplace plans for routine preventive visits. Medicaid managed care plans paid 25% less than Medicare plans and more than 40% less than marketplace plans.
A Stanford Medicine study found that pop-up messages warning of social media harms, such as mental health consequences, can reduce young people's use and boost their knowledge of risks. The study, which tested 14 warnings, found that messages on overall mental health harms, depression, and anxiety resonated most with young people.
Recent health tech advancements include drone delivery for organ transportation, AI tools in education with potential risks to childhood development, and early cancer neurotechnology research. Consumer wearables are shifting towards data interpretation, with wearable platforms needed to provide meaningful insights from collected data.
The study shows that the initial state of platinum-on-carbon catalyst particles significantly influences the development of polymer electrolyte fuel cell catalyst inks. Controlling this initial state allows for the optimization of microstructural and electrochemical properties of catalyst inks, leading to improved fuel-cell performance.
A new AI-powered system is being developed to discover new polymeric materials, reducing waste and accelerating innovation. The system integrates multiple tools, including polymer databases, predictive models, and automated laboratories, to create a self-automated workflow that refines itself.
A new method using femtosecond lasers enables the fabrication of ultrafine quantum-dot pixels with high precision and color purity for micro-LEDs. The method produces well-defined monochromatic red and green arrays with clear boundaries, achieving luminous uniformities of 90% and 97%.
This study compared clinical characteristics and outcomes between hospital-acquired and community-acquired pleural infection in a large Chinese patient population. The results showed that hospital-acquired pleural infections were more common, had more resistant pathogens, and resulted in higher mortality rates compared to community-acq...
Researchers from Fudan University developed a strategy to achieve efficient engraftment of macrophages in peripheral organs using Mr BMT, a technique that replaces microglia in the CNS. The study shows that Mr BMT preserves tissue homeostasis and innate immune response, with durable macrophage replacement lasting at least 9 months.
PDRG1 expression is significantly upregulated in HCC tissues and associated with advanced tumor stage and poor prognosis. PDRG1 activates the Wnt/β-catenin pathway, promoting cell proliferation, migration, and invasion.
A team of material scientists creates a highly fatigue-resistant eutectogel using a nanocavitation reinforcement strategy. The eutectogel is integrated into a triboelectric smart glove that captures dynamic hand gestures and recognizes sign language with 99.9% accuracy using deep learning algorithms.
Researchers found altered gene expression in wharf roach guts after consuming expanded polystyrene, but no significant impact on lifespan. The gut microbiome showed little change, but rare microbes were detected in EPS-fed specimens. This highlights the need to manage EPS waste carefully and prioritize coastal cleanup efforts.
A new hydrogel treatment, MXene-based composite hydrogel, disrupts bacterial biofilms in periodontitis, while reprogramming immune cells to reverse bone resorption. The treatment uses a dual mechanism of biofilm disruption and immunometabolic reprogramming to break the cycle of infection-inflammation-bone resorption.
Researchers developed an adipose-targeted microneedle patch co-delivering semaglutide and rosiglitazone, which achieves potent weight reduction and relieves glucolipid metabolic disorders. The patch works by alleviating inflammation and creating supportive conditions for fat browning, offering a sustainable clinical obesity intervention.
Combinatorial optimization is increasingly aided by large language models, which help with modeling, heuristic design, and end-to-end solving. The models assist in reducing expert burden and improving adaptability in complex settings.
Researchers developed dynamic electrostatic cladding-spun core-shell photothermal yarns that combine high mechanical strength with excellent photothermal performance. The yarns achieve stable photothermal temperatures and evaporation rates, demonstrating long-term operational stability. When integrated with thermoelectric modules, they...
Researchers developed a novel mosaic nanoparticle vaccine platform to overcome the mucus barrier challenge, inducing broad neutralizing effects against diverse coronaviruses. The approach breaks through respiratory physiological barriers to establish robust frontline defenses.
A research team developed a method to modify a promising photocatalytic material using flash joule heating, resulting in a 10-fold enhancement in CO evolution under simulated solar irradiation. The work establishes a universal, scalable methodology for designing high-performance photocatalysts for diverse energy conversion applications.
A researcher at Carilion Clinic has received a $623,000 NIH award to investigate the use of psilocybin to treat cocaine addiction. The study aims to evaluate the safety and efficacy of psilocybin in combination with psychotherapy for patients with cocaine use disorder.
High-entropy ceramics (HECs) exhibit superior wear resistance and adaptive lubrication compared to conventional ceramics due to synergistic effects of lattice distortion and sluggish diffusion. However, the field faces three major bottlenecks: standardized test protocols, mechanisms of high-entropy effect, and high synthesis cost.
Researchers have developed a new method to determine the high-resolution structure of 7TM proteins in a lipid bilayer using ultrafast magic angle spinning (MAS) NMR. This technique allows for detailed structural information while preserving the native-like membrane protein structure, overcoming limitations associated with proton–proton...
Mantle cell lymphoma treatment may be improved by considering a patient's biology and risk level, rather than age alone. High-risk patients can be identified at diagnosis and treated with targeted therapies, while low-risk patients may receive less intensive treatment.
Researchers at the University of Gothenburg identified a link between specific gut bacteria activities and primary sclerosing cholangitis, a rare chronic liver disease. Elevated levels of the metabolite ImP, formed by gut bacteria breakdown, can predict poorer survival outcomes and induce liver inflammation in PSC patients.
A new study published in the Journal of Experimental Biology suggests that gene activity in the nervous system is linked to rescue behavior in ants. The researchers found that ants that showed rescue behavior had 15 genes more active in their mushroom bodies, which are involved in learning and behavioral control.
A team of scientists engineered lattice and defects of nanosized metal halide perovskites using nickel doping to improve X-ray imaging performance. The modified perovskites exhibited exceptional light yield and imaging resolution, with a spatial resolution of 16.6 lp mm−1.
This study proposes BioPINN-LM, a hybrid framework for rapid wall-stress prediction and conversational risk interpretation in ascending thoracic aortic aneurysms. The framework outperforms baseline models and achieves high accuracy in wall-stress prediction and conversational decision support.
Researchers developed a 3D micro-bladder model to test phage therapy on UTI bacteria. The treatment successfully wiped out bacteria in hidden reservoirs, reducing the risk of recurrent infections. The study suggests a two-pronged approach combining phages and antibiotics may be more effective.
Researchers have discovered the underlying mechanism of Atg2-mediated lipid transfer in autophagy, revealing two distinct mechanisms that enable proper growth of the autophagosomal membrane. The phosphorylation of a specific region of Atg2, mediated by Atg1, enables its binding to the endoplasmic reticulum and subsequent lipid transfer.
Scientists from Tokyo University of Science developed a new strategy to create glassy plastics that are both stiff and tough. They achieved this by using a combination of a comb-shaped architecture and bulky counterions, resulting in materials that are approximately four times tougher and twice as stiff as conventional glassy polymers.
A team of researchers has shed light on the mechanism of outer membrane protein assembly in bacteria, revealing key conformational changes made by a chaperone protein. The study's findings may help identify new targets for antibacterial agents and improve our understanding of Gram-negative bacteria's resistance to antibiotics.
A research team at Osaka Metropolitan University mapped molecular gas throughout Stephan's Quintet, a nearby group of interacting galaxies. They found that regions with turbulent gas formed stars less efficiently, even with abundant gas present. Turbulence prevents gas from settling and collapsing, creating fewer opportunities for star...
The study found that prescriptions for GLP-1 weight-loss medications increased 310-fold among young children with obesity, from 0.03% in 2019 to 9.3% in 2026. Younger children with severe obesity and girls were more likely to receive the medications, highlighting the need for better access and monitoring.