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Science News for December 6, 2024


Network-based analyses uncover how neuroinflammation-causing microglia in Alzheimer’s disease form

Researchers have developed a network-based approach to understand how immune cells called microglia transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study identified three unique subtypes of harmful microglia that promote disease progression, with genetic signatures driving their behaviors.

SourceCleveland Clinic·JournalAlzheimer’s & Dementia·DateDec 6, 2024

Common food poison toxin speeds colon cancer spread

A study led by UF Health Cancer Center researchers found that a toxin in the bacteria Campylobacter jejuni accelerates the spread of colorectal tumors. The findings could lead to new tools for detecting metastatic colorectal cancer early, ultimately helping determine patients who need more aggressive treatments.

SourceUniversity of Florida·JournalCell Host & Microbe·TypeExperimental study·DateDec 6, 2024

Single mutation in H5N1 influenza surface protein could enable easier human infection

Researchers discovered a single mutation in the H5N1 virus that improves its ability to attach to human cells, potentially making it easier for humans to become infected. The study's findings stress the importance of continued genomic surveillance and public health preparedness to monitor potential genetic changes.

Living in a disadvantaged neighborhood linked to higher blood pressure and lower cognition

Researchers at Wake Forest University School of Medicine found a strong association between living in disadvantaged neighborhoods and higher blood pressure and lower cognitive scores. The study analyzed data from over 500 adults aged 55+ and used the Area Deprivation Index to measure neighborhood disadvantage.

SourceAtrium Health Wake Forest Baptist·JournalAlzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·DateDec 6, 2024

Developing highly efficient recovery materials for precious 'rare earth metals' and improving resource circulation for digital infrastructure

KIST researchers develop a nanostructured composite fiber material to efficiently recover rare earth metals from waste permanent magnets and industrial wastewaters. The material achieves high adsorption capacities, outperforming conventional adsorption materials.

SourceNational Research Council of Science & Technology·JournalAdvanced Fiber Materials·DateDec 6, 2024

Hybrid theory offers new way to model disturbed complex systems

A hybrid method links bottom-up behaviors and top-down causation in a single theory to capture interactions between small-scale behaviors and system-level properties in disturbed systems. The approach has been tested in examples such as post-fire forest ecosystems and pandemics, predicting ecological patterns and system dynamics.

SourceSanta Fe Institute·JournalProceedings of the National Academy of Sciences·DateDec 6, 2024

The first mouse strain that is susceptible to severe COVID-19 without genetic modification has been identified

Scientists at The Jackson Laboratory have identified the CAST/EiJ mouse as a highly susceptible model for studying severe COVID-19. This genetically pure background allows researchers to investigate the virus's impact without artificial receptor modifications, mirroring human responses. Initial trials using antiviral treatments show pr...

SourceJackson Laboratory·JournalScientific Reports·TypeExperimental study·DateDec 6, 2024

Influence of global warming and human activity on mercury accumulation patterns in wetlands across the Qinghai-Tibet Plateau

Research reveals two unique mercury accumulation patterns in Qinghai-Tibet Plateau wetlands, driven by climate change and human impact. The study found a 'Surface Peak' in monsoon-controlled regions and a 'Subsurface Peak' in westerly-controlled regions, highlighting the need for ecological sustainability efforts.

SourceScience China Press·JournalNational Science Review·DateDec 6, 2024

New model for replication of BKPyV virus, a major cause of kidney transplant failure

Researchers discovered that BKPyV's large tumor antigen is expressed after the first round of cellular DNA replication, suggesting new drug targets to prevent kidney transplant failure. The study offers a possible solution by targeting host proteins required for re-replication, reducing the likelihood of virus resistance.

SourceUniversity of Alabama at Birmingham·JournalPLOS Pathogens·TypeExperimental study·DateDec 6, 2024

Military director presence on boards of directors increase the likelihood of CEO accountability for poor firm performance

The study found that military directors are more inclined to attribute performance shortfalls to the CEO and advocate for stricter accountability, resulting in CEO dismissal. Military directors' influence is more pronounced when serving on a nominating committee.

SourceStrategic Management Society·JournalStrategic Management Journal·TypeData/statistical analysis·DateDec 6, 2024

American Society of Anesthesiologists’ statement regarding Anthem’s policy reversal on anesthesia care payment

Anthem's revised policy reverses its previous plan to stop paying for anesthesia care after a certain time limit, a move that would have compromised patient safety. The American Society of Anesthesiologists welcomed the decision, highlighting the need for fair payment for anesthesiologists to ensure adequate care for vulnerable patients.

Love thy neighbor

Researchers at ISTA discovered novel network structures that boost cooperation throughout a system. These structures have the potential to be applied in biology, particularly in bioreactors, to speed up evolution and cultivate microorganisms. The findings could also improve cooperation in computer science-based systems.

SourceInstitute of Science and Technology Austria·JournalProceedings of the National Academy of Sciences·DateDec 6, 2024

Autonomous imaging robot plays a crucial role in assessing embryos’ response to environmental change

The LabEmbryoCam is a robotic instrument that autonomously monitors embryonic development in aquatic species, providing insights into how environmental conditions impact early life stages. The open-source instrument enables scientists to track key features such as heart rate and growth in large numbers of embryos simultaneously.

SourceUniversity of Plymouth·JournalHardwareX·TypeExperimental study·DateDec 6, 2024

Researchers map genetic variants associated with pancreatic cancer in Brazilian patients

A pioneering study of 192 Brazilian patients with pancreatic ductal adenocarcinoma identified genetic variants associated with the disease. The researchers found that 6.25% had pathogenic germline variants in genes predisposing to pancreatic cancer, and 13% had variants in genes associated with limited or previously unknown associations.

Outcomes worse for patients who develop pressure sores after acute spinal cord injury

A study published in JAMA Network Open found that hospital-acquired pressure ulcers are associated with poorer neurological outcomes and reduced motor function in patients with acute cervical spinal cord injury. The findings suggest that preventing pressure ulcers can help protect these patients and lead to improved medical care.

SourceOhio State University Wexner Medical Center·JournalJAMA Network Open·TypeObservational study·DateDec 6, 2024

Getting a grip on health norms

A groundbreaking study has established the world's largest and most geographically comprehensive international norms for handgrip strength, covering 2.4 million adults from 69 countries. The new norms enable global peer-comparison, health screening, and surveillance across the adult lifespan, helping clinicians identify people at risk ...

SourceUniversity of South Australia·JournalJournal of Sport and Health Science·TypeObservational study·DateDec 6, 2024

DOE partners with UK’s DESNZ and Tokamak Energy Ltd. to accelerate fusion energy development through a $52M upgrade to the privately owned ST40 facility

The US Department of Energy (DOE) is partnering with the UK's Department of Energy Security and Net Zero (DESNZ) and private fusion company Tokamak Energy Ltd. to upgrade the privately owned ST40 facility for $52 million. This collaboration aims to advance fusion science and technology needed for a future fusion pilot plant.

Record-low Antarctic sea ice can be explained and forecast months out by patterns in winds

Researchers at the University of Washington used a global climate model to simulate how ocean and air temperatures affect sea ice in the Southern Ocean. They found that warm Southern Ocean conditions and patterns in winds can explain 70% of the record-low winter sea ice extent in 2023, with similar predictions made for 2024.

SourceUniversity of Washington·JournalCommunications Earth & Environment·TypeComputational simulation/modeling·DateDec 6, 2024

NRL hosts NASA astronaut Loral O’Hara

Loral O'Hara, a NASA astronaut, visited the Naval Research Laboratory to share her 200+ day mission aboard the International Space Station. She discussed her daily routine, scientific research, and the challenges faced by the crew, highlighting the importance of space exploration for advancing human knowledge.

Entrepreneurs who take funding from close family and friends are more likely to pursue lower-risk growth options

New research from Indiana University finds that accepting funding from family and friends can lead entrepreneurs to make more conservative venture growth decisions. This 'funding-source-induced bias' can result in anticipated guilt, prompting founders to prioritize lower-risk strategies.

SourceIndiana University·JournalJournal of Business Venturing·TypeExperimental study·DateDec 6, 2024

High heat is preferentially killing the young, not the old, new research finds

A new study reveals that 75% of heat-related deaths in Mexico occur among people under 35, contrary to the assumption that elderly individuals are more susceptible. Young adults and small children are particularly vulnerable due to factors such as outdoor labor, limited access to air conditioning, and developing immune systems.

SourceColumbia Climate School·JournalScience Advances·TypeMeta-analysis·DateDec 6, 2024

Oxygen redistribution in the brain

A team at Zhejiang University developed a novel strategy for early detection of high-altitude hypoxic brain injury using changes in oxygen content in brain regions over time. They found that brain regions with higher tolerance for hypoxia received less oxygen to support supply to more important areas.

SourceWiley·JournalAngewandte Chemie International Edition·TypeExperimental study·DateDec 6, 2024

Rice researchers examine why people remember certain things and not others

Researchers Fernanda Morales-Calva and Stephanie Leal explored the three Ws of memory - what, where, and when - to understand why people remember certain things. They found that emotional content, personal significance, repetition, and attention can influence memory retention. The study highlights the importance of considering individu...

SourceRice University·JournalCognitive Affective & Behavioral Neuroscience·TypeLiterature review·DateDec 6, 2024