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Science News for December 5, 2024


UT Health San Antonio study links genetic changes to social behavior differences in autism, schizophrenia

A UT Health San Antonio study found that brain volume changes correlate with social behavior differences in psychiatric conditions such as autism spectrum disorder and schizophrenia. Tbx1 deficiency was associated with decreased brain volume in the amygdala and surrounding cortical regions, affecting desire for social interaction.

SourceUniversity of Texas Health Science Center at San Antonio·JournalMolecular Psychiatry·TypeExperimental study·DateDec 5, 2024

Whiteness as a fundamental determinant of health in rural America

A recent study labels whiteness as a fundamental determinant of health in rural America, highlighting unique factors that contribute to poorer health outcomes. Rural white Americans face higher rates of heart disease, stroke, and cancer compared to their urban counterparts due to limited access to healthcare and socioeconomic disparities.

SourceGeorgetown University Medical Center·JournalAmerican Journal of Public Health·TypeCommentary/editorial·DateDec 5, 2024

BeginNGS® newborn screening by genome sequencing shown to be safe and effective in two clinical studies

The BeginNGS platform uses genome sequencing and artificial intelligence to detect rare genetic diseases in newborns, achieving a 97% reduction in false positives. This technology has the potential to save thousands of lives by providing earlier diagnoses and treatment.

SourceRady Children's Institute for Genomic Medicine·JournalAmerican Journal of Human Genetics·TypeComputational simulation/modeling·DateDec 5, 2024

Coastal retreat in Alaska is accelerating because of compound climate impacts

Scientists warn that Alaska's Arctic Coastal Plain will experience unprecedented transformation due to the compounding effects of sea level rise, permafrost thaw subsidence, and erosion. By 2100, total land loss is expected to exceed erosional losses by up to eight times, posing new challenges to coastal communities.

SourceWoods Hole Oceanographic Institution·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateDec 5, 2024

Researchers: If Power-to-X is to be a real climate solution, the state needs to use the stick

A study by University of Copenhagen researchers highlights the challenges in investing in green hydrogen projects, citing market risks, regulatory uncertainty, and high costs. Oil and gas companies are better positioned to finance large-scale hydrogen projects due to their expertise and infrastructure.

SourceUniversity of Copenhagen - Faculty of Science·JournalEnvironment and Planning A Economy and Space·DateDec 5, 2024

From one gene switch, many possible outcomes

A team of researchers has discovered that subtle changes in a lipid-binding region can dramatically alter the function of transcription factors in plants. By swapping the START domains of two near-identical paralogs, PHB and CNA, the researchers demonstrated that this single change could rewrite developmental instructions.

SourceUniversity of Pennsylvania·JournalNature Communications·TypeExperimental study·DateDec 5, 2024

Novel quantum materials in the spotlight

German physicist Christian Schneider has been awarded a European Research Council Consolidator Grant to study the optical properties of two-dimensional materials. His team plans to develop experimental set-ups to investigate the unique properties of these materials, which could lead to new applications in quantum technologies.

Climate change threatens global food supply: Scientists call for urgent action

An international team of researchers warns that climate change could lead to widespread food shortages and famine if rapid changes are not made to develop climate-resilient crops. The group emphasizes the need for unprecedented collaboration between scientists, farmers, policymakers, and the public to address this crisis.

SourceBoyce Thompson Institute·JournalTrends in Plant Science·TypeCommentary/editorial·DateDec 5, 2024

Q&A: What fossils reveal about ancient Australian forests and fire

Fossil evidence from Australia and South America challenges prevailing narrative that eucalypt forests are under siege from expanding rainforests. The study suggests that fire became a feature of these vegetation interactions in Australia around five million years ago, making large-scale fire interventions unnecessary.

SourcePenn State·JournalNew Phytologist·TypeObservational study·DateDec 5, 2024

X-ray data-enhanced computational method can determine crystal structures of multiphase materials

Researchers develop a computational method to determine the crystal structures of multiphase materials directly from powder X-ray diffraction patterns. This approach can analyze existing experimental data that was previously difficult to decipher, leading to potential discoveries of new material phases.

SourceSchool of Science, The University of Tokyo·JournalThe Journal of Chemical Physics·TypeComputational simulation/modeling·DateDec 5, 2024

Shaking sensor continuously monitors inflammation

A new implantable device, inspired by a tree branch, uses DNA sensors to continuously monitor inflammation biomarkers in the body. The device accurately measures protein biomarkers of inflammation in diabetic rats and has potential applications for managing acute and chronic conditions.

SourceNorthwestern University·JournalScience·TypeExperimental study·DateDec 5, 2024

DGIST develops nitrogen-doped catalyst technology to accelerate hydrogen fuel cell commercialization

A research team at DGIST has developed a breakthrough technology that improves fuel cell durability by incorporating nitrogen into alloy catalysts. The new method significantly enhances stability and reduces platinum usage, leading to more efficient and sustainable energy solutions.

SourceDGIST (Daegu Gyeongbuk Institute of Science and Technology)·JournalJournal of the American Chemical Society·DateDec 5, 2024

Cancer research: Small change with a big impact

Researchers at the University of Konstanz have discovered that different mutations of the tumour suppressor p53 affect pancreatic carcinomas differently. The study found that two variants of p53 selectively control distinct metabolic pathways, providing new insights into cancer development.

SourceUniversity of Konstanz·JournalJournal of Experimental & Clinical Cancer Research·DateDec 5, 2024

Opioids interfere with cancer immunotherapy but these drugs could help

New research from the University of Pittsburgh found that opioids can suppress the immune system and reduce the effectiveness of immunotherapy for head and neck cancer. However, peripherally restricted OPRM1 antagonists (PAMORAs) may block opioid-induced immunosuppression and improve response rates to immune checkpoint inhibitor therapy.

SourceUniversity of Pittsburgh·JournalJournal for ImmunoTherapy of Cancer·DateDec 5, 2024

Innovative immunotherapy shows promise in early clinical trial for breast cancer

A groundbreaking phase one clinical trial explores a novel cell-based immunotherapy for breast cancer, demonstrating significant shrinkage of tumors and minimal side effects. The treatment leverages dendritic cells to trigger an organized immune system attack on cancer, offering hope for replacing or reducing the need for chemotherapy.

SourceKent State University·JournalJAMA Oncology·TypeRandomized controlled/clinical trial·DateDec 5, 2024

Revolutionizing railroad safety: A deep learning approach to remote condition monitoring

A new deep learning model enhances railroad condition monitoring by combining Convolutional Neural Networks (CNNs) and Long Short-Term Memory (LSTM) networks, achieving 97% accuracy in detecting train positions and conditions. The model's real-time processing capabilities enable swift intervention and mitigation of potential hazards.

SourceBeijing Institute of Technology Press Co., Ltd·JournalGreen Energy and Intelligent Transportation·TypeExperimental study·DateDec 5, 2024

Scripps Research scientists identify mutation that could facilitate H5N1 “bird flu” virus infection and potential transmission in humans

Researchers discovered a single amino acid mutation in the H5N1 'bird flu' virus that enhances its ability to attach to human cells, potentially increasing the risk of person-to-person transmission. The finding highlights the need for ongoing surveillance of H5N1 mutations that pose risks to public health.

SourceScripps Research Institute·JournalScience·DateDec 5, 2024

Providing performance information of peers as a management tool?

A recent study found that when employees are given information on their colleagues' performance, many continue to operate in a way that is not necessarily more efficient or innovative. Instead, they may ignore negative feedback or reinterpret it in a positive light due to their own self-image and tendency towards self-enhancement. To f...

SourceKühne Logistics University·JournalOrganization Science·TypeExperimental study·DateDec 5, 2024

Controlling cancer cells’ gluttony for glutamine

Researchers at Sanford Burnham Prebys found that pancreatic cancer cells rely on a specific nutrient, glutamine, to fuel their unchecked growth. The study identified two enzymes, aPKC zeta and iota, that play a regulatory role in the process of macropinocytosis, allowing cancer cells to scavenge alternative resources.

SourceSanford Burnham Prebys·JournalNature Communications·TypeExperimental study·DateDec 5, 2024

UNC researchers awarded up to $10M to leverage data science to accelerate cancer diagnosis and optimize delivery of precision oncology

A team of UNC-Chapel Hill researchers will develop an oncology health learning system using AI-ready data to generate real-time identification of new cancer cases and support personalized treatments. The project aims to improve cancer diagnosis, care equity, and quality by creating accessible tools for health providers.

Groundbreaking study reveals impact of calendering on electrochemical-mechanical performance of silicon-based composite electrodes

Researchers uncover the effects of calendering on silicon-based composite electrodes, revealing increased deformation and cracking with higher calendering levels. This study offers valuable insights for optimizing electrode design and improving battery safety.

SourceBeijing Institute of Technology Press Co., Ltd·JournalGreen Energy and Intelligent Transportation·TypeExperimental study·DateDec 5, 2024

The future of more sustainable cooling and heating technology could be just around the corner

A team of researchers from the U.S. Department of Energy Ames National Laboratory developed a magnetocaloric heat pump that matches current vapor-compression technology in terms of weight, cost, and performance. The device eliminates refrigerant emissions and requires less energy to operate, offering a promising alternative for cooling...

SourceDOE/Ames National Laboratory·JournalApplied Energy·DateDec 5, 2024

A film capacitor that can take the heat

Researchers used a machine-learning technique to accelerate discovery of materials for film capacitors, identifying a compound with record-breaking performance. The study aims to improve capacitor shielding properties and enhance energy savings in common electric power applications.

SourceScripps Research Institute·JournalNature Energy·DateDec 5, 2024

Breakthrough in electric vehicle technology: Advanced SOC estimation using random forest

A new study introduces a novel algorithm that utilizes Random Forest to estimate State of Charge (SOC) in Electric Vehicles (EVs), achieving superior accuracy and robustness. The RF model outperforms traditional methods, including Extreme Learning Machine, and holds promise for enhancing EV efficiency and reliability.

SourceBeijing Institute of Technology Press Co., Ltd·JournalGreen Energy and Intelligent Transportation·TypeExperimental study·DateDec 5, 2024

Gene editing and plant domestication essential to protect food supplies in a worsening climate, scientists say

Scientists emphasize the need for gene editing and plant domestication to protect food supplies due to the climate crisis. Researchers propose two strategies: introducing genes that support resistance to environmental stress into existing crops or domesticate wild plants with lower yields but higher resilience.

SourceFrontiers·JournalFrontiers in Science·TypeLiterature review·DateDec 5, 2024

Feminist mothers may be compromising their own children's sex education at home

A study by the University of Surrey found that self-identified feminist mothers in England often struggle to balance their values with the need to protect their children from gendered risks. Despite advocating for open and honest communication about sexual rights, safety, and wellbeing, they may adopt protective strategies that contrad...

SourceUniversity of Surrey·JournalSex Education·TypeObservational study·DateDec 5, 2024

New study finds neurobiological evidence of peripartum depression in women, distinguishing it from major depressive disorder

Researchers have identified structural grey matter differences in the brains of women with a history of peripartum depression compared to those without. The study found that hormone fluctuations during pregnancy and childbirth may be key to understanding this condition.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateDec 5, 2024

Separating signal from noise in the brain

Researchers at the University of Tokyo discover that the patterns of spontaneous activity and stimulus-evoked response are similar in lower visual areas of the cerebral cortex but gradually become independent as one moves to higher visual areas. This orthogonal relationship helps explain how sensory perception remains stable despite co...

SourceUniversity of Tokyo·JournalNature Communications·TypeImaging analysis·DateDec 5, 2024

Imaging technique allows rapid assessment of ovarian cancer subtypes and their response to treatment

A new MRI-based imaging technique can rapidly assess ovarian cancer subtypes and their response to treatment, allowing for personalized treatment planning. The technique, called hyperpolarised carbon-13 imaging, distinguishes between two different subtypes of ovarian cancer and reveals their sensitivities to treatment.

SourceUniversity of Cambridge·JournalOncogene·TypeExperimental study·DateDec 5, 2024

Special needs children respond positively to new emotional literacy programme in new RCT

A new emotional literacy programme adapted for special schools has shown promising results, suggesting significant benefits for children with learning disabilities. The study found improvements in mental health and behaviour among participants, highlighting the potential of such programmes in improving quality of life.

SourceUniversity of Birmingham·JournalPublic Health Research·TypeExperimental study·DateDec 5, 2024

Scientists ‘turn up the heat’ on understanding coffee wilt disease which threatens our favourite daily brew

Repeated outbreaks of coffee wilt disease have decimated coffee production in east and central Africa, with scientists identifying a fungal pathogen as the primary cause. The study found that horizontal gene transfers contributed to the repeated emergence of the disease, which affects arabica and robusta varieties.

SourceCABI·JournalPLOS Biology·TypeExperimental study·DateDec 5, 2024

Ethnic studies boosts critical thinking, equity awareness in high school students

A University of Michigan study suggests that ethnic studies courses develop critical reflection, a core component of critical consciousness, enabling students to recognize and challenge systemic inequities. Students also valued the content and teaching methods in ethnic studies classes, which emphasized cooperative learning and direct ...

SourceUniversity of Michigan·JournalDevelopmental Psychology·DateDec 5, 2024

New study highlights rise in severe Shigella infections among homeless patients in Vancouver

A recent study found a significant increase in severe multidrug-resistant Shigella sonnei infections among people experiencing homelessness (PEH) in Vancouver. The strain, genotype 3.6.1.2, is resistant to nearly all antibiotics, leading to higher hospitalization rates and more severe outcomes.

SourceUniversity of British Columbia·JournalClinical Infectious Diseases·TypeObservational study·DateDec 5, 2024

Long COVID-19 is costing Americans money

A new study from the University of Georgia found that long COVID-19 is making it harder for people to pay their bills, buy groceries, and keep utilities on. Individuals with lower incomes are disproportionately affected by food insecurity and inability to pay bills due to the condition.

SourceUniversity of Georgia·JournalHealth Services Research·DateDec 5, 2024

Discovering the mechanism behind brain’s inhibition network: From vision to action control

Researchers from Juntendo University discovered a four-step neural pathway involved in response inhibition, involving visual processing, sensory integration, action control, and execution of inhibition. The study aims to develop targeted therapeutic strategies for conditions like ADHD and obsessive-compulsive disorder.

SourceJuntendo University Research Promotion Center·JournalNature Communications·TypeImaging analysis·DateDec 5, 2024

Proposed wastewater release into Cape Cod Bay likely to remain in bay for at least one month, study finds

Scientists predict the proposed wastewater release into Cape Cod Bay will stay in the bay for at least a month, with seasonal winds affecting its spread. The study used high-resolution ocean circulation models to simulate the plume's behavior and found that the majority of the water will come close to the shore before leaving the bay.

SourceWoods Hole Oceanographic Institution·JournalJournal of Physical Oceanography·TypeObservational study·DateDec 5, 2024

Buffalo besties: Feral female buffalo build friendships based on similar personality traits

A new study has discovered that close spatial proximity serves as an indicator of friendship in feral female buffalo, with individual personalities playing a key role. The research found that buffalo with similar social tension, vigilance, and general dominance traits tended to spend more time together.

Food allergy anxiety at 30,000 feet

A global survey of over 4,700 food allergy patients and families found airline travel to be a significant source of worry and anxiety. The study suggests that reasonable accommodations, such as pre-boarding and allergen-free zones, can reduce stress for travelers with food allergies.

SourceNorthwestern University·JournalJournal of Allergy·DateDec 5, 2024

Preparing for the worst: Healthcare can check readiness for bird flu spread

Infectious disease experts suggest that hospitals closely monitor local and national cases of bird flu and screen patients with flu-like symptoms for contact with farm animals. Effective communication is essential for fostering trust and reducing anxiety among healthcare personnel, patients, and the public.

SourceSociety for Healthcare Epidemiology of America·JournalInfection Control and Hospital Epidemiology·TypeCommentary/editorial·DateDec 5, 2024

A blueprint for the brain's circadian clock

A team of researchers has created the first complete map of the brain's circadian clock in the fly Drosophila, revealing at least 240 neurons involved in regulating daily rhythms. This detailed mapping provides a foundation for exploring circadian dysregulation linked to health conditions such as sleep disorders and metabolic diseases.

SourceUniversity of Würzburg·JournalNature Communications·TypeImaging analysis·DateDec 5, 2024

Open those windows: Natural ventilation in historic buildings can reduce mechanical system use, save energy and create healthier indoor environments

Researchers at Drexel University investigated natural ventilation strategies in historic homes to understand how their inherent energy-efficient features can inform modern energy conservation efforts. The study found that passive cooling and cross-ventilation can achieve energy savings and improve thermal comfort, particularly in hot a...

SourceDrexel University·JournalEnergy and Buildings·TypeComputational simulation/modeling·DateDec 5, 2024

Unveiling unknown chemicals in human serum samples

A study by Chiba University researchers has identified 106 compounds in pregnant women's serum samples, including phthalates, nitrogenous compounds, and parabens, which may impact biological pathways. The study proposes a non-targeted approach for detecting foreign chemicals and evaluating their potential health effects.

SourceChiba University·JournalEcotoxicology and Environmental Safety·TypeData/statistical analysis·DateDec 5, 2024