A new Ohio State University clinical trial investigates whether probiotics can help patients with ovarian cancer better tolerate chemotherapy. The study aims to reduce treatment side effects and improve quality of life. Researchers will examine changes in the gut microbiome and its link to treatment response.
Researchers at Ohio State University Wexner Medical Center developed a combination treatment that targets CD276 protein and disrupts mitochondria, killing cancer cells and slowing tumor growth in preclinical models of triple-negative breast cancer. The findings suggest a possible new approach to treat this hard-to-treat form of breast ...
A phase I clinical trial at Ohio State University Wexner Medical Center demonstrated positive results for enhanced CAR T-cell therapy targeting B-cell blood cancers. The treatment resulted in minimal side effects and improved treatment outcomes for patients with relapsed or treatment-resistant B-cell blood cancers.
Researchers at Ohio State University Wexner Medical Center found that chronic stress during pregnancy changes how the placenta communicates with the developing fetus, affecting early brain development. Prenatal stress alters placental signaling and opposes maternal immune activation effects in the fetal brain.
Researchers at Ohio State University are testing psilocybin-assisted therapy to reduce depression and emotional distress in patients with advanced lung cancer. The trial aims to determine whether this approach can address the unique psychological challenges faced by lung cancer patients.
Researchers will analyze blood samples from the OPTI-AML clinical trial to identify biomarkers for treatment resistance. The goal is to develop new therapies for patients with resistant disease, accelerating treatment decisions based on individual patient biology.
Researchers at Ohio State University Wexner Medical Center are studying the effects of menopause on women veterans' mental and physical health. The four-year project aims to identify biological pathways linked to symptom severity and inform personalized treatments.
According to a national survey commissioned by The Ohio State University Wexner Medical Center, most U.S. adults believe brain health habits should begin before age 40. Regular exercise, quality sleep, healthy eating, and strong social connections can help support long-term brain health.
A new wearable electric-field device has been shown to slow the growth and spread of aggressive breast cancer in preclinical models. The technology uses low-intensity electric fields that interact with cancer cells in a controlled way, reducing tumor growth and increasing immune responses.
A national survey of 1,006 adults found that only 71% of young adults have a primary care doctor, compared to 97% of older adults. Fewer than half of young adults who do have a doctor have had a checkup in the past year.
Researchers at Ohio State University Wexner Medical Center have developed a first-ever vaccine against leishmaniasis, a disease putting 10% of the world at risk. The vaccine is expected to start clinical trials this year and has shown 100% effectiveness in animal studies.
Researchers from Ohio State University Comprehensive Cancer Center present new findings on a hospital program that redistributes unused oral cancer drugs donated by patients. The program helps patients avoid treatment delays caused by insurance issues, shipping problems or cost, and has been shown to reduce drug delays by six days.
A new Ohio State University study aims to raise awareness of the link between alcohol consumption and breast cancer risk among young women. The study uses targeted messages to educate participants about the risks and encourage reduced drinking habits.
A new survey found that nearly half of women incorrectly believe annual mammograms should start at age 50. Experts recommend yearly mammograms starting at age 40 for average-risk women. This delay can lead to cancers being found at a later stage, when treatment can be more complex.
Researchers at Ohio State University Wexner Medical Center are refining specialized lymphatic microsurgery techniques to treat and prevent lymphedema. The new procedures, including lymphatic bypass and lymph node transfer, offer patients more options and improved quality of life.
A national analysis found that higher e-cigarette prices and taxes both reduced vaping among adults, with no increase in cigarette consumption. Researchers suggest that tiered tax designs may be necessary to curb nicotine use.
A new survey by Ohio State University Wexner Medical Center finds that only 42% of Americans are open to using AI in their healthcare, down from 52% in a previous survey. The decline in trust is attributed to concerns about AI's accuracy and the potential for it to replace human judgment in medical decision-making.
Researchers developed a blood-based test that analyzes circulating tumor HPV DNA to inform personalized treatment strategies for HPV-associated throat cancer. The study found that ctDNA levels change before and after surgery, influenced by tumor biology and kidney function.
Researchers found that inhibiting glucose transport can overcome tumor resistance to chloroquine treatment by inducing mitochondrial damage and oxidative stress. The study suggests a new combination therapy strategy for treating lung squamous cell carcinoma and subsets of adenocarcinoma with limited treatment options.
Researchers at Ohio State University Wexner Medical Center found that stellate ganglion block enhances the effectiveness of cognitive processing therapy for treating PTSD, leading to faster symptom reduction and improved outcomes.
A survey by Ohio State University Wexner Medical Center reveals that 76% of people don't complete their physical therapy homework. Adding home exercises to routines can help successful recovery and reduce the need for additional medical procedures.
A nationwide survey found that 61% of Americans are unaware of non-statin medications to lower cholesterol, while 73% have never heard of lipoprotein(a) or coronary artery calcium score testing. Non-statin options include Ezetimibe, PCSK9 Inhibitors, and Bempedoic Acid, which can help patients at risk for heart disease.
The BRIDGE Program provides coordinated support across disease types to address the rising issue of early-onset cancer, offering fertility counseling, genomic testing, and community education. The program also fuels research into tumor biology and outcomes for younger patients affected by cancer.
A survey by Ohio State University Wexner Medical Center reveals that nearly all Americans are unaware of the comprehensive women's health services provided by certified nurse-midwives. Only 20% know about annual gynecology exams, while 93% are aware of pregnancy and birth support.
A nationwide telehealth clinical trial is now open at Ohio State University Wexner Medical Center for adults with advanced or metastatic pancreatic cancer with specific mutations in the fibroblast growth factor receptor (FGFR) gene. The study will test pemigatinib, a smart drug targeting these genetic mutations.
Obstructive sleep apnea is increasingly being diagnosed in younger adults, challenging the stereotype that it only affects older or overweight individuals. Many people with sleep apnea remain undiagnosed due to daytime fatigue and overlooked symptoms like snoring or choking.
Researchers at Ohio State University have found that cancer immunotherapy fails due to a collapse in protein quality control, leading to T-cell exhaustion. This discovery offers a new avenue for cancer immune therapy development by targeting the protein production cycle.
A multidisciplinary team analyzed the interaction between neurons and glial cells, revealing key pathways that could be pivotal in neurodegeneration. The study highlights the importance of understanding cellular crosstalk in developing effective treatments for Alzheimer's.
A recent survey by Ohio State University Comprehensive Cancer Center found that 80% of Americans are unaware of the lack of noticeable symptoms in early-stage prostate cancer. The disease is treatable if caught early, and regular screening is crucial.
A new survey by Ohio State University Wexner Medical Center reveals that many people are unaware of the connection between knee, groin, and hip pain. The study found that 72% of respondents were not aware that knee pain could be a sign of a hip problem.
A mobile phone app designed to deliver suicide-specific therapy reduced suicidal behavior among psychiatric inpatients by 58.3%. Users experienced sustained reductions in suicidal thoughts for up to 24 weeks after hospitalization.
A new survey conducted by Ohio State University Wexner Medical Center highlights the widespread emotional impact of cancer on adults when a loved one is diagnosed. Cancer anxiety can significantly impact long-term survival, with up to five times the likelihood of depression among cancer patients compared to the general population. The ...
A national survey of 1,000 American adults found that stress (43%) and lack of sleep (39%) are major contributors to a short attention span. The study also identified digital devices as a significant factor, with 35% of respondents citing it as a contributing factor.
A new survey conducted by Ohio State University Wexner Medical Center found that only 1% of men are concerned about bone density, with cancer and heart disease being top concerns. Men can build back bone density through exercise, nutrition, and lifestyle changes, and early intervention can prevent deadly fractures.
Researchers at Ohio State University have developed blood tests to diagnose pancreatic cancer and predict treatment outcomes. Genetic information can also help predict breast cancer survival rates, while a new blood test may improve treatment response for patients with advanced sarcoma. These findings offer promising tools for early de...
Researchers at Ohio State University discovered that women's hearts beat faster due to higher levels of genes like TBX3 and HCN1. In contrast, men's hearts are more prone to irregular rhythms like atrial fibrillation, linked to inflammation and collagen production.
Researchers at Ohio State University have identified new targeted therapies for treating small cell lung cancer, predicting melanoma spread, and reducing endometrial cancer risk. A 31-gene expression profile has been developed to identify patients at high risk of melanoma spread, allowing for closer monitoring and earlier treatment.
W. Kimryn Rathmell, former NCI director, joins Ohio State as CEO of The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. She will lead the clinical and research excellence of Ohio State's cancer program, including operational oversight of both hospitals.
Researchers have found that targeting PGM3 can help stop the growth of glioblastoma, a fast-growing brain tumor. By blocking this enzyme, tumors can be effectively suppressed.
Adapted Argentine tango dance therapy is helping some breast cancer survivors regain natural balance and sensation after experiencing neuropathy, a common side effect of chemotherapy treatment. The therapy aims to rewire the brain to improve function after chemotherapy-related nerve changes.
Researchers at Ohio State University Wexner Medical Center have discovered a new way that neurons act in neurodegeneration by studying human neural organoids from patients with frontotemporal lobar degeneration (FTLD). They found GRAMD1B plays a significant role in managing cholesterol and lipid stores, which are linked to brain diseas...
A survey of 1,068 women reveals that many believe they will hit menopause in their 40s, despite symptoms starting earlier. Experts emphasize the importance of addressing changes and concerns with a doctor to find effective treatment options.
A survey reveals that most people are unaware of HPV's impact on cancer risk and its spread. The human papillomavirus (HPV) is more common among men than women, and the virus is associated with rising rates of oropharyngeal cancers, which can take years to develop after initial infection.
A new survey found that many Americans believe common symptoms like fatigue and nausea are normal during and after pregnancy, while ignoring signs of potential heart problems. The Ohio State University Wexner Medical Center is calling for better awareness and care for pregnant women with pre-existing health issues.
A systematic review of 17 studies found strong associations between functional impairments and hospital readmissions across various health conditions. Assessing patients' physical function early and often during hospitalization may help ensure care is aligned with key priorities for discharge.
A national survey of 1,008 Americans found that nearly two-thirds use a device to monitor their heart health, but only one in four shares the data with their doctor. This lack of sharing can lead to delayed diagnosis and treatment, emphasizing the importance of proactive communication between patients and healthcare providers.
A study published in JAMA Network Open found that hospital-acquired pressure ulcers are associated with poorer neurological outcomes and reduced motor function in patients with acute cervical spinal cord injury. The findings suggest that preventing pressure ulcers can help protect these patients and lead to improved medical care.
A new survey by Ohio State University Wexner Medical Center finds that 56% of Americans prioritize alone time for mental health, while 46% don't get enough during the holidays. Dr. Sophie Lazarus suggests taking brief breaks alone to reduce stress and improve mental well-being.
A new study published in JAMA Network Open found that brief cognitive behavioral therapy via video telehealth reduces suicide attempts and suicidal ideation, providing critical insight into treatment options for those struggling with suicidal thoughts. The study also shows that this therapy is effective in reducing depressive symptoms.
A new survey by Ohio State University shows that most people believe pancreatic disease affects only the elderly and that there is nothing they can do to reduce their risk. However, obesity increases lifetime risk for pancreatic cancer by 20%.