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Ohio State University Wexner Medical Center


ASCO 2026: Ohio State researchers highlight cancer drug donation program, lung and breast cancer treatment, Lynch syndrome screening, access to clinical trials and more

Researchers from Ohio State University Comprehensive Cancer Center present new findings on a hospital program that redistributes unused oral cancer drugs donated by patients. The program helps patients avoid treatment delays caused by insurance issues, shipping problems or cost, and has been shown to reduce drug delays by six days.

ASCO 2025: Pancreatic cancer blood tests, genetic predictors of breast cancer survival and sarcoma treatment response prediction tools among Ohio State findings

Researchers at Ohio State University have developed blood tests to diagnose pancreatic cancer and predict treatment outcomes. Genetic information can also help predict breast cancer survival rates, while a new blood test may improve treatment response for patients with advanced sarcoma. These findings offer promising tools for early de...

Study reveals why women tend to have faster heartbeats, men more irregular rhythms

Researchers at Ohio State University discovered that women's hearts beat faster due to higher levels of genes like TBX3 and HCN1. In contrast, men's hearts are more prone to irregular rhythms like atrial fibrillation, linked to inflammation and collagen production.

SourceOhio State University Wexner Medical Center·JournalCirculation Arrhythmia and Electrophysiology·TypeComputational simulation/modeling·DateMay 15, 2025

AACR 2025: Colon cancer risk reduction, predicting melanoma spread and new drug therapies among Ohio State findings

Researchers at Ohio State University have identified new targeted therapies for treating small cell lung cancer, predicting melanoma spread, and reducing endometrial cancer risk. A 31-gene expression profile has been developed to identify patients at high risk of melanoma spread, allowing for closer monitoring and earlier treatment.

Ohio State study reveals new insights into neurodegeneration using human ‘mini brains’

Researchers at Ohio State University Wexner Medical Center have discovered a new way that neurons act in neurodegeneration by studying human neural organoids from patients with frontotemporal lobar degeneration (FTLD). They found GRAMD1B plays a significant role in managing cholesterol and lipid stores, which are linked to brain diseas...

SourceOhio State University Wexner Medical Center·JournalNature Communications·TypeExperimental study·DateApr 9, 2025

Survey: While most Americans use a device to monitor their heart, few share that data with their doctor

A national survey of 1,008 Americans found that nearly two-thirds use a device to monitor their heart health, but only one in four shares the data with their doctor. This lack of sharing can lead to delayed diagnosis and treatment, emphasizing the importance of proactive communication between patients and healthcare providers.

Outcomes worse for patients who develop pressure sores after acute spinal cord injury

A study published in JAMA Network Open found that hospital-acquired pressure ulcers are associated with poorer neurological outcomes and reduced motor function in patients with acute cervical spinal cord injury. The findings suggest that preventing pressure ulcers can help protect these patients and lead to improved medical care.

SourceOhio State University Wexner Medical Center·JournalJAMA Network Open·TypeObservational study·DateDec 6, 2024

First-ever randomized clinical trial uses telehealth for suicide prevention

A new study published in JAMA Network Open found that brief cognitive behavioral therapy via video telehealth reduces suicide attempts and suicidal ideation, providing critical insight into treatment options for those struggling with suicidal thoughts. The study also shows that this therapy is effective in reducing depressive symptoms.

SourceOhio State University Wexner Medical Center·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateNov 12, 2024

Study explores how traumatic brain injury (TBI) may be linked to Alzheimer’s disease

Researchers found TBI increases hyperphosphorylated tau, astro- and microgliosis, synaptic dysfunction and cognitive impairments linked to developing Alzheimer’s. BAG3 overexpression ameliorates tau hyperphosphorylation, synaptic dysfunction and cognitive deficits through the enhancement of the autophagy-lysosome pathway.

SourceOhio State University Wexner Medical Center·JournalActa Neuropathologica·TypeExperimental study·DateOct 15, 2024

Study explores novel therapeutic treatment for glioblastoma

A study by Ohio State University researchers found that combining pimozide with CB-839 can effectively suppress glioblastoma growth by blocking lipid production and starvation of tumor cells. This innovative combination may also hold promise for treating other cancers relying on glutamine and lipids.

SourceOhio State University Wexner Medical Center·JournalCell Reports Medicine·TypeRandomized controlled/clinical trial·DateOct 7, 2024

Study shows therapy dog program works as needed mood-booster for health care workers

A pilot study by Ohio State University Wexner Medical Center found that therapy dog interactions increased self-reported positive mood nearly doubling among healthcare workers. The program improved work engagement and reduced emotional exhaustion, burnout, and stress among staff.

SourceOhio State University Wexner Medical Center·JournalInternational Journal of Complementary & Alternative Medicine·DateSep 16, 2024