A new study by Ohio State University found that nearly half of U.S. counties lack a retail pharmacy within 10 miles, exacerbating health disparities and impacting medication adherence. The study highlights the consequences of limited pharmacy accessibility on communities with higher social vulnerabilities.
A new study by Ohio State University Wexner Medical Center found that probiotics can improve the immune system and behavior of both mothers and their offspring during pregnancy. Probiotics may also help counteract negative effects of prenatal stress, such as changes in brain inflammation and amino acid metabolism.
A new study published by Ohio State University has found that vaping combined with cigarette smoking increases the risk of lung cancer four times higher than people who only smoke. Researchers analyzed data from over 4,975 patients with lung cancer and a control group of 27,294 people without cancer.
A new study published in JAMA Network Open shows that an at-home fecal immunochemical testing (FIT) screen can reduce the risk of colorectal cancer death by 33%, comparable to screening colonoscopy. FIT is a non-invasive test that involves mailing a stool sample to the laboratory for analysis.
Researchers found that patients with sickle cell disease experience significant distress from anticipating and attending emergency departments to manage acute pain flares. The study also revealed stigma and racism in care settings, leading to a lack of control over pain management plans.
Researchers found that WIC enrollment was associated with lower rates of gestational diabetes, preterm birth, blood transfusions, and ICU admissions. This suggests that programs like WIC can improve pregnancy health.
A study by Ohio State University researchers found that chemotherapy disrupts the gut microbiome in breast cancer patients, leading to cognitive decline and increased inflammation. The research suggests that targeting the gut microbiome may improve behavioral side effects of chemotherapy.
Neuroscience researchers at Ohio State University have discovered a special type of human white blood cell that has the potential to regrow nerve fibers. The study found that these cells can triple the survival rate of stressed nerve cells and help slow or prevent progression of degenerative neurological conditions.
A randomized controlled trial at Ohio State University Wexner Medical Center found that using the SAGE test during routine appointments led to a sixfold increase in early diagnoses. The study demonstrated the effectiveness of this simple, self-administered tool for detecting cognitive impairment.
Researchers identified a unique approach to preventing abnormal nerve growth and autonomic dysfunction after spinal cord injury. Depleting microglia cells was found to be effective in preventing life-threatening complications, which significantly improves quality of life for people with spinal cord injuries.
A comprehensive, user-friendly repository has been created to help study Alzheimer's disease. The ssREAD database encompasses 277 integrated datasets from 67 scRNA-seq & snRNA-seq studies, totaling 7,332,202 cells, and includes interactive visualizations for comprehensive analysis interpretations.
A new study at Ohio State University Wexner Medical Center found that standardizing seizure action plans improves epilepsy management. The study involved 204 adult patients, who showed significant improvement in seizure management after receiving structured SAPs.
A new study from Ohio State University Wexner Medical Center found that treating anxiety and depression significantly improves heart disease outcomes, with a 75% reduction in hospitalizations or emergency room visits. The study suggests a collaborative care model is essential for managing cardiovascular and mental health.
A study by Ohio State University Wexner Medical Center found that crisis response planning can rapidly reduce suicidal thoughts among U.S. military members and veterans receiving massed cognitive processing therapy for PTSD. The intervention was tested in a randomized controlled trial involving 157 participants, with promising results.
The $20 million SOAR study aims to identify key risk and resiliency factors affecting behavioral health. The research will inform strategies to improve treatment options and patient outcomes in the state of Ohio.
Researchers found that the severity of muscle wasting depends on the location of the spinal cord injury. They also discovered that hypercortisolism, a hormonal imbalance, worsens muscle loss and can be targeted to rescue muscle tissue.
Researchers at Ohio State University Wexner Medical Center found that oral nicotine pouches do not curb current smokers' nicotine cravings effectively. The study suggests that these products may be more appealing to young people due to their longer onset time and gradual relief from craving symptoms.
A new non-invasive pain management device has been shown to reduce opioid use after childbirth by nearly half. The study, conducted at Ohio State University Wexner Medical Center, found that the device was effective in managing post-cesarean pain without the need for opioids.
A new clinical trial tested the efficacy of nemtabrutinib in patients with relapsed blood cancers, including CLL and NHL. The results showed a 75% response rate, with many patients remaining cancer-free for at least 16 months.
Researchers at Ohio State University will investigate the role of microglia cells in chronic inflammation and neuronal dysfunction after TBI, with a focus on preventing long-term consequences. The $7.7 million award aims to develop innovative healthcare solutions for traumatic brain injury survivors.
A recent study from Ohio State University Wexner Medical Center and colleagues found that Rumination-focused Cognitive Behavioral Therapy (RF-CBT) can reduce rumination in adolescents. The study also showed correlated shifts in brain connectivity, suggesting that RF-CBT can help young people break the painful mental loops that contribu...
Researchers at Ohio State University Wexner Medical Center are testing a novel diagnosis and treatment combination for painful diabetic neuropathy using spinal cord stimulation and small fiber nerve activity measurement. The approach has the potential to provide effective pain relief and potentially reverse neuropathy reversal.
The Ohio State University has been awarded a $20 million grant to conduct research on tobacco product regulation and its impact on public health. The center will examine how nicotine levels affect tobacco use, develop strategies to reduce youth appeal, and monitor the tobacco industry's marketing tactics.
A new study by Ohio State University found that most gynecologic cancer-related content on TikTok is poor in quality and accuracy. The majority of the content, over 73%, was deemed inaccurate and of poor educational quality, with racial disparities also present.
Research found that depression screening methods, such as the Patient Health Questionnaire-9, correctly identified more patients who attempted suicide than suicide risk screenings. The study suggests that comprehensive screenings tools may be more effective in identifying patients at risk of suicide and depression.
The new guidelines provide a framework for genetic testing and counseling, recommending comprehensive testing and gene-targeted therapies for all persons with ALS. The guidelines aim to improve access and standardize practice among neurologists and genetic counselors.
Researchers have discovered that gene therapy may prevent relapse in patients with serious alcohol addiction by altering dopamine function in the brain's mesolimbic reward pathway. The treatment involves sustained release of glial-derived neurotrophic factor (GDNF) in a specific region of the brain.
A new study from Ohio State University Wexner Medical Center found that restricting sweet flavorings and cooling agents in e-cigarettes could significantly reduce youth vaping rates. Nearly 39% of survey respondents would quit using their e-cigarettes if tobacco-flavored e-liquids were the only options available.
A new device invented by Emile Daoud and his team at Ohio State University Wexner Medical Center significantly reduces the risk of esophageal injury during heart ablation. The device uses suction force to gently move the esophagus away from the catheter tip, creating a safe pathway for treatment.
A new study found that being overweight or obese during early and middle adulthood increases the risk of gastrointestinal cancers in later life. The research also suggests that frequent aspirin use does not modify this increased risk.
A new study found that remote outreach involving interactive education and follow-up support via telephone increased breast, cervical, and colorectal cancer screening rates among rural women. The combination of a remotely delivered interactive DVD and patient navigation services resulted in a six-fold increase in screenings.
A recent study found that immunotherapy alone resulted in a 89% favorable treatment response rate for patients with desmoplastic melanoma. This suggests that combination therapies may not be necessary for these patients, reducing the risk of toxicity.
A recent study has found a significant link between fibromyalgia and increased odds of exacerbation in pain-related opioid use disorder. Researchers surveyed 125 individuals living with both conditions, revealing that those with fibromyalgia were more likely to report worsening addiction symptoms due to chronic pain.
Researchers investigated a remote dietary intervention to reduce chronic cancer-related fatigue in lymphoma survivors, with encouraging preliminary data suggesting effectiveness. Participants showed significant improvement in self-reported fatigue and overall healthful eating patterns.
A new study highlights the dramatic impact of the COVID-19 pandemic on cancer-screening delays, with significant delays observed among younger individuals and diverse populations. The study found that 11%-36% of planned cancer screenings were postponed due to COVID-19, with the greatest delays seen for Pap tests and colonoscopies.
Researchers at Ohio State University Comprehensive Cancer Center have developed a new model system to study human CD8 T-cell dysfunction and found that boosting bone morphogenetic protein 4 (BMP4) while blocking transforming growth factor beta 1 (TGFβ1) preserves the function of chronically stimulated T cells. This approach improved re...
Researchers at Ohio State University Wexner Medical Center are developing non-invasive biomarkers for radiation exposure using Raman spectroscopy and mass spectrometry-based methods. The project aims to improve early detection and risk assessment of radiation exposure, which can lead to serious health problems and delayed consequences.
A recent mouse study published in Diabetes found that maternal and paternal exercise significantly improved metabolic health in offspring. The study used metabolomics profiling to examine the effects of parental exercise on tissue metabolites, revealing extensive changes in glucose and fatty acid metabolism.
Researchers found reduced lung function and scarring in mice exposed to e-cigarette vapor with or without nicotine. Female mice also showed increased body weight in adulthood. The study suggests vaping during pregnancy can have long-term health effects on offspring.
The COVID-19 pandemic has seen a significant increase in years of life lost to unintentional drug overdose among adolescents, with synthetic opioids like fentanyl contributing to the rising trend. Researchers found that mortality due to unintentional overdose in adolescents reached an all-time high in 2020.
A new study led by Ohio State University researchers found that atezolizumab is a safe and effective treatment option for stage IB-IIIB non-small cell lung cancer patients prior to surgery, with survival rates reaching 80% at three years post-treatment. The study also identified new blood markers that can help predict treatment response.
A groundbreaking crowdsourced study has provided the first epidemiologic data on coma in the United States and United Kingdom. The research, involving nearly 2,000 participants, identified 714 plausible cases of common coma, providing critical insights into its incidence and causes.
A new wireless sock monitoring system reduced fall rates among 'fall-risk' patients by zero falls, compared to a historical rate of 4 falls per 1,000 patient-days. The system uses pressure sensors and interrelated devices to detect patient attempts to stand up and alert nurses through a notification system.
Researchers found that participants who received cooking education showed improvements in eating more vegetables, fewer carbohydrates, and lower A1C levels. The study also highlighted the importance of addressing food insecurity in diabetes management.
A study published in PAIN Reports found that individuals with opioid use disorder (OUd) experience greater central sensitization, leading to worse quality of life. Central sensitization refers to abnormal pain processing in the brain and spinal cord, causing people to suffer more from pain.
Researchers identify key features of a gene mutation responsible for 15-20% of melanomas, establishing a link between the frequency of specific NRAS mutations and spontaneous melanoma formation. The study could help pinpoint early events required for melanoma formation and develop targeted treatments.
Researchers at Ohio State University Wexner Medical Center have discovered a new molecular drug target to treat cancer, VEGF-A, which can increase expression of dopamine D2 receptors on endothelial cells to stop blood vessel growth and spread diseases like colon cancer and ovarian hyperstimulation syndrome.
Researchers say expanded inquiries can save lives by identifying vulnerable individuals who may not be reporting suicidal ideation. Tailoring assessments to individual situations can help medical professionals uncover hidden risks and prevent tragedies.
A new study found that nearly one-third of older adult female survivors of colorectal, endometrial, and ovarian cancer experience quality-of-life-impacting challenges with physical activity due to chronic lower extremity lymphedema. The researchers urge the medical community to include regular lymphedema assessments in survivorship care.
A new study published in Circulation finds that vaping has a significant and long-term cardiovascular effect on adolescent males, reducing heart function over time. In contrast, female mice exposed to e-cigarette aerosol showed no significant changes in heart function or levels of the enzyme CYP2A5, which breaks down nicotine.