A new study by Northwestern University found that syphilis rates are nearly twice as high among transgender women and Black gay and bisexual men compared to white gay men. The study suggests that preventing and treating syphilis requires outreach to key populations, particularly those from communities of color.
Researchers discovered an anti-nucleolin DNA aptamer that modulates gene expression and nucleolin localization to determine a cell's lineage during differentiation. The study shows promise as a regenerative therapy for cardiovascular diseases.
A multilevel primary care intervention, including electronic health record reminders and patient outreach, improved timely follow-up of overdue abnormal cancer screening test results for breast, cervical, colorectal, and lung cancer. The intervention was found to be effective in reducing missed screenings.
Researchers at Yale University found a protein, CXCR4, plays a crucial role in modulating the immune system during pregnancy. The study suggests that this protein may be targeted for new treatments of reproductive conditions such as recurrent pregnancy loss and preeclampsia.
A young star cluster, IRS13, has been found to be significantly younger than expected, with stars only 100,000 years old, despite being near the supermassive black hole Sgr A*. The cluster's turbulent history suggests it was 'captured' by the black hole's gravity, leading to a bow shock and increased star formation.
Researchers at the University of Virginia Health System are developing computer models to better understand the cellular processes and gene activity of multi-drug resistant bacteria Staphylococcus aureus and Pseudomonas aeruginosa. The goal is to identify vulnerabilities in these bacteria and advance the development of new treatments.
A large multi-state study found that mupirocin ointment is highly effective at preventing Staphylococcus aureus infections in critically ill patients, outperforming an antiseptic solution. The study involved over 800,000 ICU patients in 137 hospitals and showed a durable benefit from mupirocin.
A team of scientists developed a microwave microstrip line planar resonator sensor to detect added water in honey. The sensor's resonance frequency shifts with increased water content, allowing for adulteration detection.
A study by Johns Hopkins Children's Center investigators found that delaying surgical treatment of the anterior cruciate ligament (ACL) in some children is associated with a higher risk of new tears in the meniscus and cartilage. Adults, on the other hand, showed no significant increase in such risk.
Having obesity before and during early pregnancy is linked to adverse outcomes like high blood pressure, preeclampsia, and gestational diabetes. These complications account for a small percentage of increased cardiovascular disease risks in the years following pregnancy for people with obesity.
Researchers discovered early Cambrian microfossils preserving introvert musculature of cycloneuralians, a group of animals that include roundworms and horsehair worms. The preserved musculature consists of four groups of muscles, differing from basal animals in terms of topology.
A study published by Vienna University of Technology analyzed the effects of extreme physical and mental stress on a rowing athlete's body. The research found that the variability in heart rate, sleep quality, and regeneration during sleep phases were closely related to the athlete's psychological condition.
A dispute over fossil rights led to mud-slinging between professors from Cambridge and London Universities in the 1970s. The researchers found that Professor Parrington's team took four tons of clay rich in fossils from quarries in South Wales, sparking a heated debate.
A multilevel intervention combining automated reminders and patient outreach improved follow-up rates for patients with overdue abnormal cancer screening results. The study found that such interventions can enhance patient outcomes through earlier diagnosis and treatment.
Researchers at Drexel University developed a titanium oxide material that can break down two common dye pollutants in water under visible light. The material reduced rhodamine 6G and crystal violet concentrations by 90% and 64%, respectively, in just 30 minutes.
The University of Houston has received $5 million in DOE funding to develop high-performance superconducting tapes. The project aims to improve manufacturing efficiency and reduce costs, enabling the technology's widespread adoption in clean energy applications.
Researchers found that the medial septum, a brain area in the center of the forebrain, plays a key role in encoding and retrieval processes. It helps generate gamma oscillations, which are faster for storing and slower for recalling memories.
Researchers from the University of Notre Dame found that social media engagement improves when national and local levels mismatch audiences during recovery phases, increasing user engagement by 29.6%. The study suggests a nuanced approach to content coordination, with national headquarters leading production and local accounts following.
A new study found that hybrid closed-loop technology significantly improved maternal blood sugars in pregnant women with type 1 diabetes. Women who used the technology spent more time within the target range for pregnancy blood sugar levels, gained less weight, and had fewer complications.
A research team developed a data fusion strategy combining near-infrared spectroscopy (NIRS) and laser-induced breakdown spectroscopy (LIBS) for fast and accurate detection of compound fertilizer components. The approach improved accuracy by up to 33.5% compared to LIBS alone.
Researchers from Kobe University found that birds dispersing the eggs of eaten insects' help flightless stick insects expand their geographical range. Genetic analysis revealed a correlation between geographic distance and genetic differentiation among populations.
A University of Massachusetts Amherst team demonstrates a protein antigen from a childhood vaccine can be delivered into malignant tumor cells to refocus the immune system against cancer. The bacteria-based intracellular delivering system shows promise in treating pancreatic, liver, and metastatic breast tumors.
A University at Buffalo-led research team has developed molecules that can transport chloride ions across cell membranes, increasing airway surface liquid and restoring normal mucus clearance in cystic fibrosis cells. The synthetic anion binders offer a new potential treatment for the chronic disease.
Researchers have developed a new protocol to test the toxicity of micro- and nano-plastics in various organisms, considering particle-specific properties and dynamic behavior. The protocol takes between 24h to 2 months and can be applied by students, academics, and industries.
Researchers discovered that people carrying three Neanderthal gene variants in the SCN9A gene are more sensitive to certain types of pain. The study found an association between the variants and a lower pain threshold in response to skin pricking after prior exposure to mustard oil.
A new study from George Mason University found that women with a disability are more likely to report child marriage compared to women without disabilities. The study found that women with disabilities were over one and a half times more likely to experience girl child marriage.
A recent study by Carnegie Mellon University and ShanghaiTech University found that China's government subsidies have had limited effect on promoting firms' productivity. The study analyzed firm-level data from 2007 to 2018 and found that subsidies often flowed to less productive firms, leading to a decline in their relative productivity.
This study investigates the regulatory role of methylation in vernalization and photoperiod pathways, revealing its potential as a flowering regulator. The authors summarize current knowledge on methylation's involvement in these pathways, highlighting its heritability and potential replacement of vernalization/photoinduction.
A research team from Heinrich-Heine University Düsseldorf has clarified an important mechanism in how fungal infections are regulated at the molecular level. They discovered a single RNA-binding protein called Khd4 that controls the growth of infectious hyphae by determining mRNA stability, which in turn regulates membrane trafficking.
Researchers at IISc have developed a novel method to improve pharmacokinetic properties of macrocyclic peptides, which are used in pharmaceutical industries worldwide. By substituting oxygen with sulphur in the backbone of these peptides, they increase resistance to digestive enzymes and lipophilicity, thereby boosting bioavailability.
Researchers tested the feasibility of using locally run LLMs like Vicuna-13B to label key findings in chest X-ray reports while preserving patient privacy. The results showed moderate to substantial agreement with non-LLM computer programs, suggesting that these models can be a viable option for AI research.
The author estimates that AI-related electricity consumption could increase by 85-134 TWh annually by 2027, comparable to the annual electricity consumption of countries like the Netherlands and Sweden. The growth highlights the need for mindful AI adoption to minimize energy-intensive applications.
The GALAXY CRUISE project has published its first scientific paper, showing that colliding galaxies increase the rate of new star formation. Citizen astronomers helped classify over 2 million galaxies in data from the Subaru Telescope, enabling this groundbreaking research.
Research reveals that the illegal killing of orangutans on Borneo remains a significant threat to the species, with 30% of villages reporting killings in the last 5-10 years. Conservation efforts may not be effectively preventing killing and addressing human-orangutan conflict is crucial.
A new study suggests that stress and certain gastrointestinal factors can exacerbate menopause symptoms. Women with constipation experience more severe symptoms compared to those with normal stool consistency, according to the research.
Researchers from the University of Tokyo have synthesized a complex with two zinc ions that exhibit color, greatly expanding the potential properties of zinc complexes. The discovery uses visible light to move electrons between orbitals, resulting in a yellow material.
A study found that renting in the private sector is associated with faster biological ageing, but this effect can be reversed through policy changes. The research emphasizes the importance of housing policy in improving health outcomes.
A recent study compared using health information exchange (HIE) data with patient self-reported data as a means of gathering intelligence on cancer screening uptake. HIE data provided more information about laboratory screening tests, while patient self-reports offered more details about cancer screening procedures.
Engineers at UC San Diego developed wireless, battery-free force stickers that measure the force exerted by one object on another. The stickers can be used in various applications, including biomedical devices, industrial equipment monitoring, and inventory management.
Research found that poor sleep quality is associated with less muscle strength and mass, more body fat, anxiety, and depression in obese older people. The study emphasizes the importance of addressing sleep quality to prevent negative health outcomes in this population.
A new study found that pre-pregnancy obesity is a primary driver of future cardiovascular disease risk, rather than pregnancy complications. The research followed 4,216 individuals from early pregnancy to postpartum and found those with overweight or obese BMI had a higher risk of developing hypertensive disorders during pregnancy.
A new study from the University of Kansas found that mandated disaster plans have mediocre quality and modest improvements over time. Despite regular updates, the plans fail to address key issues such as public engagement and land use policies, leading to repeated mistakes in areas prone to natural disasters.
Researchers found that incel ideology on TikTok uses emotional appeals and pseudo-science to share extremist views, normalising harmful ideologies. The study highlights the need for policymakers to understand the growing incel activity on mainstream platforms like TikTok.
A randomized controlled trial found that nonalcoholic beverages significantly reduced alcohol consumption in adults, with the reduction persisting after 8 weeks. The study suggests that these beverages may replace alcoholic drinks in consumption.
Pre-contact agave species cultivated by early cultures like the Hohokam people continue to persist in Arizona's landscape. These domesticated agaves are distinct from their wild counterparts and offer a rare opportunity to study plant species unchanged since prehistory.
Researchers from Hefei Institutes of Physical Science discovered a novel reassembly process for G-quadruplexes through Hoogsteen SDR, revealing unique recognition modes between probes and targets. This breakthrough offers new possibilities for GQ reassembly and insights into G-rich DNA interactions.
Researchers developed an AI tool that can detect valvular heart disease with 93% sensitivity and 98% specificity. The tool analyzes audio data from a short burst of sound vibrations using a contact microphone and neural networks, allowing for quick identification of five different valvular diseases.
Mutations in the EMC1 gene are associated with familial exudative vitreoretinopathy (FEVR), a severe ocular condition. The discovery highlights the pivotal role of EMC1 in retinal blood vessel development via the Wnt signaling pathway.
A phase 2 clinical trial found that serial blood tests can identify patients who benefit from additional immunotherapies, suggesting a potential early marker of treatment response. The study also showed that ctDNA analyses correlated with tumor size and survival, making it a promising strategy for guiding therapy.
A new study found that Medicare Advantage generally had lower resource use and cost compared to traditional Medicare for many conditions, but not all. For example, MA used fewer resources for conditions like rheumatoid arthritis and diabetes, where proper care management can prevent hospitalizations.
Researchers have successfully mimicked plant power through artificial photosynthesis, producing methane from carbon dioxide and sunlight. The breakthrough could pave the way toward replacing nonrenewable fossil fuels with sustainable energy sources.
A new study reveals FGF18 as a key inducer of hepatic stellate cell proliferation and liver fibrosis. FGF18 levels are dramatically elevated in fibrotic livers, and its overexpression induces liver fibrosis in mice.
Researchers discovered elevated miR-18a-5p expression in PCa patients with bone metastases, which inhibited osteoblast differentiation and activity. Inhibiting miR-18a-5p improved bone biomechanical properties and bone mineral mass in a mouse model.
The center will establish a national presence in cutting-edge research areas like Human-AI Collaboration and Responsible AI. Researchers aim to develop natural language interfaces for robots like Boston Dynamics' Spot, increasing its useful tasks and navigating environments on its own.
A new AI tool developed by Brazilian researchers can detect potentially cancerous lung nodules in CT reports, missing a crucial early diagnosis. The NLP tool achieved an accuracy rate of 97% in identifying suspicious nodules.
Researchers found tropical forest ecosystems rely more on aquatic insects than temperate forests, making them vulnerable to disruptions in land-water connections. This increased reliance poses a threat to tropical environments, which are already under pressure from human activity and climate change.
The University of Oklahoma is part of a $104 million federal initiative to study antibiotic resistance, led by Harvard Medical School professor Johan Paulsson. The project aims to understand how antibiotic resistance arises and characterize rare cells that survive during antibiotic treatments.
Researchers at MIT have discovered that the sounds produced by rocks under different pressures can reveal their depth and strength, helping scientists identify unstable regions below the surface. This new method could aid in drilling for geothermal energy and understanding the Earth's crust.
Researchers have found that benzoxazinoids, a special plant defense compound, evolved independently in distantly related plant families. The study used two species, golden dead-nettle and zebra plant, to elucidate the metabolic pathway of these compounds, revealing unexpected diversity in enzymes performing the same reactions.
Researchers introduce a game-changing technology that enables fabrication of high-resolution, transformable 3D structures at the micro/nanoscale using Two-photon polymerization-based (TTP-based) 4D printing. The technology has vast potential for applications in biomedicine, flexible electronics, soft robotics, and aerospace.