A new American Heart Association advisory introduces the concept of cardiovascular-kidney-metabolic (CKM) syndrome, which affects nearly every major organ. The approach highlights the importance of screening for CKM-related conditions and addressing social factors to prevent progression.
The ancient Maya built and maintained reservoirs that filtered and cleaned the water using aquatic plants, providing potable water for thousands of people. The Maya's approach to managing water quality could serve as a model for addressing today's water crises.
Researchers have identified a massive solar storm 14,300 years ago in ancient tree rings, which could be catastrophic for modern technological society. The study warns of the importance of understanding such storms to protect global communications and energy infrastructure.
The American Ornithological Society (AOS) has awarded four $15,000 Kessel Fellowships to support the research of Dr. Lucia Mentesana and three others focused on conservation, behavior, evolution, and ecology. The fellowships aim to advance ornithology globally by funding innovative projects.
A new generative model named scPoli enables multi-scale representations of cells and samples, facilitating the integration of high-quality large-scale datasets for novel biological insights and disease understanding. This model accelerates atlas building and usage, ultimately accelerating disease understanding and therapy development.
Researchers call for a more structured approach to integrating simulation technologies into medical and teacher training, highlighting their potential but also concerns about subpar training without evidence. Simulation-based learning tools offer new possibilities for students to develop skills in realistic environments.
The SNEB position paper highlights the critical issue of food insecurity among college students, emphasizing the importance of systemic approaches and student advocacy. Research shows that food insecurity is associated with unhealthy dietary habits, less sleep, and higher odds of mental health issues.
The USC Norris Comprehensive Cancer Center has received a $10 million grant from The Ralph Lauren Corporate Foundation to launch the Ralph Lauren Center for Cancer Prevention. This new center aims to address cancer health disparities in L.A. County by increasing access to high-quality screening, prevention services, and timely care thr...
Researchers have discovered a new mechanism for starving pancreatic cancer cells, potentially leading to improved treatment outcomes. A combination of treatments involving the drug DRP-104, which blocks glutamine metabolism, and trametinib, an existing ERK signaling pathway blocker, showed promising results in mouse models.
The newly discovered 'Margaritaville' snails, named after Jimmy Buffett's famous song, are bright yellow and have a key trait that helps them survive on coral reefs. Their brightly colored heads may serve as a warning to predators, while their mucus web traps plankton and detritus for sustenance.
Banana Xanthomonas Wilt (BXW) could cause a 55% reduction in banana production in newly affected regions within 10 years. The disease is projected to result in significant economic losses, with consumers bearing 40% of the estimated $25 billion cost.
A study found that only 3 out of 22 African countries with high TB/HIV burden have no national policy on LF-LAM test implementation. Main barriers include lack of funding and training, despite the test being less expensive than other diagnostic tests.
The new plan provides a roadmap for advancing nuclear science research programs over the next decade. It highlights FRIB's importance in advancing the field and ensures continued US leadership in nuclear physics.
Researchers found that using predictive models in healthcare can alter relationships between patient data and outcomes, leading to further degradation. Implementing a system to track individuals impacted by machine learning predictions is crucial to maintaining model performance.
The study reveals MOF's critical role in maintaining mitochondrial integrity through protein acetylation. COX17 is identified as a key target of MOF-mediated acetylation, stimulating its function and regulating oxidative phosphorylation.
Researchers at Lund University discovered that certain fungi can 'clean up' their surroundings by catching nanoplastics, reducing their toxic effects. This finding highlights the potential for fungi to mitigate soil pollution and provides hope for a more sustainable future.
Researchers at Sanford Burnham Prebys have developed a new approach to treat pancreatic cancer by feeding tumors a copycat of the important nutrient glutamine. This method significantly slowed pancreatic tumor growth and prevented the spread of tumors in early clinical trials.
The study found that increased exposure to night-time light increases the risk of psychiatric disorders such as anxiety, bipolar disorder, and PTSD severity. In contrast, increasing daytime light exposure can act as a non-pharmacological means for reducing psychosis risk and depression.
Researchers found goalkeepers have narrower temporal binding windows, indicating more precise multisensory processing and quicker estimations of audiovisual cues. They also showed less interaction between visual and auditory information, suggesting a greater tendency to separate sensory signals.
A new study by James Stroud at Georgia Tech and Jonathan Losos at Washington University in St. Louis found that natural selection varies massively through time among four different species of anoles living together on a small island. Despite this variation, the species remained remarkably similar across the entire time period.
A study by Boston University and UC Berkeley found that incentivized reviews are more likely to contain low-quality information and correspond to worse guest experiences. In contrast, non-incentivized reviews with the same star ratings led to better guest experiences.
Scientists at the University of Bristol have created a prediction model for a simple connection method using screws in bamboo. This innovative approach can help fight climate change by sequestering carbon at a faster rate than traditional wood, taking only four-to-five years to mature.
A study from North Carolina State University tracked 16 rehabilitated turtles to monitor their long-term survival and health. The researchers found that turtles moved an average of 100 yards between observations, with some individuals traveling much farther than expected.
A recent clinical trial demonstrates solriamfetol's effectiveness in improving ADHD symptoms in adults, with no significant impact on sleep quality. The medication also exhibited a favorable safety profile, with common side effects including decreased appetite and increased energy.
Billions of people worldwide will be exposed to unbearable heat and humidity if global temperatures increase by 1 degree Celsius or more. Regions with high population density, like Pakistan, India, China, and sub-Saharan Africa, are expected to experience frequent extreme heatwaves due to high humidity.
A new cancer drug candidate has been found to restore the effectiveness of the immune system in fighting tumors, including melanoma, bladder cancer, leukemia, and colon cancer. The drug works by lowering a toxic compound called MTA, which impairs normal functioning of immune cells and blocks immunotherapies.
The number of people who die from stroke globally is projected to increase by 50% to 9.7 million deaths per year by 2050, mainly affecting Low-Middle Income Countries (LMICs). The annual costs are estimated to reach up to US$2.3 trillion, with a disproportionate impact on LMICs.
Researchers created a new CRISPR-based gene therapy tool using locally sourced, human-derived proteins that can activate silent or insufficiently expressed genes. The DREAM tool mimics the natural ability of human cells to turn on specific genes in response to mechanical cues.
In the wake of Hurricane Harvey's record flooding, researchers discovered a unique form of evolutionary change called spatial sorting that dominated the evolution of Jadera haematoloma bugs. This rapid adaptation allowed them to access seeds on goldenrain trees, outcompeting native species with longer beaks.
A University of Maryland research team is developing a portable bio-nose device capable of identifying complex odors. The team has successfully created an insect-based cell line that can sense odors, and is now studying its responses to different liquids.
Researchers found that volcanic eruptions coincided with extreme greenhouse climate warming and mass extinctions due to large amounts of carbon dioxide released into the atmosphere. The study reveals a connection between geological and astrophysical cycles, suggesting astronomical movements control Earth's interior processes.
The study developed a highly accurate AI model for fully automated cancer detection, including small and difficult-to-detect tumors. The model could detect visually imperceptible cancer from normal-appearing pancreases substantially early before clinical diagnosis, with a median of 438 days.
A study of 23,000 adults found a significant link between depressive symptoms and increased mortality from cardiovascular disease. Public health efforts can support nationwide strategies to reduce depression's burden.
Researchers from Woods Hole Oceanographic Institution analyzed in situ observations since 2001, revealing the Gulf Stream is warming and moving towards the shore. The study used data from Argo floats and Spray underwater gliders, providing insights into the ocean's dynamics.
A new study explores the simulated universe hypothesis and its implications for science and technology. The second law of infodynamics suggests that information has mass and entropy remains constant or decreases in information systems, supporting the idea that we're living in a simulation.
A recent study found that less than one-third of TAVR patients participate in cardiac rehabilitation within 90 days after discharge. Factors such as age, frailty, and medical complexity contribute to lower enrollment rates. The study highlights the need for improved education and hospital protocols to promote post-procedure care.
A new study published in The Lancet Planetary Health found that every additional 360m of green space is associated with higher odds of anxiety and depression. The study, which analyzed data from over 2 million adults in Wales, highlights the need for improved public green spaces to address mental health inequalities.
Researchers developed AI tools to analyze speech patterns in people with schizophrenia and found that these patterns can be distinguished from those of healthy individuals. The study uses an AI language model trained on internet text to represent the meaning of words, and it was able to predict the words generated by control participan...
A WVU researcher is developing new methods to fast-track the discovery of quantum materials, which could lead to breakthroughs in fields like quantum computing and superconductors. The goal is to streamline the discovery process using computational and experimental tools.
Researchers found a significant link between geomagnetic disturbances and disruptions to nocturnal bird migration. The study used massive datasets from U.S. Doppler weather radar stations and ground-based magnetometers, revealing a 9-17% reduction in migrating birds during severe space weather events.
Researchers reconstructed a massive tectonic plate from fragments found in mountain belts around the world. They discovered that the plate, named Pontus, existed for at least 150 million years and had a significant impact on Earth's geological history.
Researchers discovered PRMT1 promotes gastric cancer cell proliferation and metastasis through β-catenin signaling. The study identified a novel mechanism involving MLXIP recruitment to activate the β-catenin pathway.
A new study shows that XEN1101 can reduce seizure frequency by more than 50% in some patients and sometimes eliminate seizures altogether. The medication, a potassium-channel opener, boosts the flow of potassium out of nerves to stop them from firing.
Research reveals correlation between financial sector risks and increased carbon footprint in bank loans, hindering humanity's progress towards a green economy. The study analyzed CFBL data for 37 countries from 2010 to 2018, finding that systemic risk within the banking sector raised the CFBL in developed countries.
An international team of scientists recommends a global shift in food choices due to the potential for addiction. They suggest that certain ultra-processed foods have characteristics similar to addictive substances, which may improve global health.
The study found that MdMYB73 activates MdPH5 expression and enhances its activity, regulating malate transport into vacuoles. This results in increased malate accumulation and vacuolar acidification.
Researchers at Children's National Hospital used magnetic resonance spectroscopy to find new biomarkers that reveal how CHD changes an unborn baby's brain chemistry. The study found altered levels of choline and N-Acetyl aspartate-to-choline ratios, potentially representing disrupted brain development.
Research suggests that the gut microbiome plays a crucial role in forming a healthy placenta during pregnancy. Mice with depleted gut microbiomes had smaller placentas and less-developed blood vessels, which can deprive fetuses of nutrients. However, supplementing these mice with short-chain fatty acids restored placental growth.
A long-term study by Georgia Tech's James Stroud found that natural selection varies massively through time, canceling out any stabilizing effect. Species remained remarkably similar across the entire three-year period, contradicting the idea of constant evolution.
The University of Tennessee Institute of Agriculture is teaming up with AT&T Foundation to address the challenge of broadband access and education through a new digital literacy program. The program will engage, invest, and train citizens in skills that improve broadband adoption, particularly in economically distressed counties.
A new study by PIK researchers reveals that less privileged people in NYC face limitations in adapting their mobility behavior to heat, leading to increased health risks. The analysis of mobility data from 438 NYC subway stations shows that those already at higher risk have the fewest options to adjust their behavior.
The study found that offshore wind could generate up to 8% of the nation's electricity by 2050, with deployment ranging from 30 to 250 gigawatts. High levels of deployment are likely in scenarios with stringent decarbonization policies and low technology costs.
A pioneering international study led by UOC researchers finds that older people in Spain and Israel use smartphones more than those in Canada and Romania due to access to affordable internet rates. The study contradicts the stereotype that growing older leads to decreased digital technology use.
Approximately 1 in 5 adolescents had major depressive disorder, with less than half receiving mental health treatment. Racial and ethnic minority groups, particularly Latinx, experienced the lowest treatment rates.
A study found that people with a specific genetic mutation in the CARD9 gene have higher IL-17 protein levels, making them more responsive to IL-17 inhibitor biologics. This discovery may lead to targeted treatment recommendations for ankylosing spondylitis patients.
A study of over 850,000 Australian children born between 2009 and 2017 found a small increased risk of birth defects among those conceived through fertility treatment, partly attributed to parental infertility. The use of intracytoplasmic sperm injection (ICSI) was also associated with an increased risk for genitourinary abnormalities.
Researchers developed an analytical tool to spot stray DNA and RNA contamination in genetic analyses, increasing result accuracy. The software, SAHMI, can identify microbe-associated cells and study microbiome distribution in tissues.
Researchers found that individuals with previous environmental, social, and nutritional stressors were more likely to die from the flu. This contradicts the widespread belief that healthy young adults were disproportionately affected. The study analyzed skeletal remains of 369 victims and identified lesions as indicators of frailty.
Researchers found that wandering albatrosses orientate towards areas of 'loud' microbarom infrasound when flying on long distance foraging trips. This suggests that they may perceive and respond to microbarom infrasound propagated over long distances.
Researchers discovered that the short-chain fatty acid propionate can reduce metastases in mice with experimental lung cancer. The substance also increases the effectiveness of Cisplatin, a commonly used drug for lung cancer patients. Funding is now sought to identify patients who may benefit from propionate treatment.