The American Society for Nutrition released a clinical advisory outlining eight key nutritional priorities to support GLP-1 therapy, including personalized diets, micronutrient prevention, and adequate protein intake. Studies have shown that patients receiving combined pharmacologic and lifestyle interventions achieve greater weight lo...
Student researchers from UTA present their original research at various conferences, including the American Chemistry Society conference and Pittcon Conference. This provides opportunities for them to network with professionals and potential employers, as well as gain hands-on experience in their field.
Researchers have developed an integrated metasurface-integrated quantum analog computing system, simplifying phase reconstruction and achieving high signal-to-noise ratio at low photon levels. This technology has broad application potential in fields such as optical chips, wave function reconstruction, and label-free biological imaging.
A plant-based diet with soybeans can significantly reduce severe hot flashes by 92% and promote weight loss of approximately 8 pounds. The level of food processing does not affect these benefits, suggesting that increasing plant foods is independent of processing level.
A new classification system for nasal deformities in infants with cleft lip and/or palate has been proposed, offering a reliable and practical tool for standardized assessment. The system provides a user-friendly approach to evaluating nasal deformities, promoting consistent diagnosis and treatment planning.
The study reveals that the crystallographic characteristics of dinosaur egg SEUs are identical to those of PEUs and modern bird eggshell units, suggesting a biogenic origin. The researchers also discovered grooves and vesicles in SEUs, consistent with organic matrix fiber degradation during fossilization.
Researchers at UT Health San Antonio discovered associations between blood lipid levels and Alzheimer's disease risk. Higher small dense cholesterol particles increased risk, while ApoB48 levels were associated with lower risk.
A groundbreaking review identifies the skin as a central hub for systemic inflammation regulation, linking it to multiple organs through bidirectional crosstalk. The study reveals IL-17A as a master regulator of multi-organ crosstalk, driving various diseases simultaneously.
Assistant professor of electrical and computer engineering Natasa Miskov-Zivanov is receiving a $581,503 NSF CAREER Award for her project that leverages AI to design more effective lymphocytes for cancer immunotherapies. The system aims to accelerate the process of designing new therapeutic cell designs.
DB-1310, a HER3-targeted antibody-drug conjugate, has shown real potential as a new treatment option for patients with advanced solid tumors that have progressed after standard therapies. In an international clinical trial, DB-1310 demonstrated significant tumor shrinkage and delayed cancer growth in 44% of EGFR-mutant NSCLC patients.
Cessation of public water fluoridation would lead to higher rates of tooth decay and increased healthcare costs in the US. The model suggests that current safe levels of fluoride have substantial ongoing benefits.
Researchers developed a smart hydrogel system that supports the growth of human salivary cells in three-dimensional spheroids. The system enables the formation of large, viable spheroids with high expression of key salivary proteins and demonstrates functional activity.
A new study predicts that limiting warming to 1.5°C could preserve over half of the world's glacier mass, but even at this level, 39% of glacier mass would still disappear due to delayed climate change reactions.
A new study led by University of Wisconsin-Oshkosh geologist Timothy Paulsen reveals evidence for lost mountains in Antarctica's past. The team analyzed mineral grains from igneous rocks in the Transantarctic Mountains, suggesting a more dynamic landscape history than previously recognized.
A study by Waseda University finds that competing corporate coalitions within boards impact a firm's spending decisions once profitability targets are met. Firms with stronger state-endorsement coalitions allocate more resources to social causes, while those with shareholder-value coalitions prioritize dividend payments.
A study conducted in collaboration with researchers from SWPS University found that practicing niceness can increase the propensity to cooperate by strengthening social bonds. The researchers conducted two studies, one measuring everyday niceness and its association with social connectedness and attitudes towards cooperation, and anoth...
A Virginia Tech professor has received a proof-of-concept grant to further develop a chemical compound that could help promote weight loss by increasing mitochondrial activity. The compound, named BAM15, shows promise in preclinical studies without affecting food intake or muscle mass.
A study unravels the complex molecular network controlling anthocyanin accumulation in horticultural plants, revealing pivotal roles of structural genes and transcription factors. The research provides valuable insights for breeding plants with improved coloration, stress tolerance, and enhanced nutritional value.
Researchers discovered a potential vulnerability in P. falciparum by inducing protein aggregation, leading to reduced parasite growth. The study may lead to novel antimalarial strategies targeting the parasite's internal protein folding machinery.
The partnership brings together two organizations with a shared commitment to scientific innovation, connecting Hertz Fellows with Breakthrough Energy's global network of climate and energy experts. The collaboration aims to advance transformative climate and energy solutions through joint programming, workshops, and shared resources.
Researchers at Osaka Metropolitan University found a mutant protein that helps plants fight mildew, but also accelerates leaf aging and yellowing. The discovery could contribute to crop yield improvement and sustainable agriculture.
A national survey of internal medicine physicians found that experiencing sacred moments is common among physicians. However, discussing these experiences with colleagues is infrequent, suggesting a potential impact on physician well-being.
This study investigates UGIT involvement in adult Egyptian UC patients, finding significant esophagitis and gastritis. The results demonstrate a strong association between colonic disease severity and UGIT endoscopic and histopathological findings.
A research team at KIST has developed a new water treatment material that can recover phosphorus with high efficiency and disinfect harmful microorganisms simultaneously. The material utilizes a 'sea urchin-shaped' nanostructure to achieve world-class phosphorus recovery performance.
Using site characterization data from multiple disciplines, researchers can now accurately predict the occurrence of marine landslides. The correct sequence of site investigations and integration of data is crucial for maximizing information and confidence in landslide models.
Researchers developed a new approach to identify healed diabetic foot ulcers at risk of reopening based on trans-epidermal water loss measurements. High TEWL values were linked to increased wound recurrence and shorter time to recurrence, suggesting functional skin barrier defects are a critical factor in wound healing.
The ECORD event will explore the importance of scientific ocean drilling in understanding Earth's systems and addressing environmental challenges. Key findings include the establishment of the new International Ocean Drilling Programme (IODP3) and its potential impact on global scientific cooperation.
A new study found that routine testing for multiple infectious diseases among migrants can identify key infections earlier, improving health outcomes and reducing onward transmission. The Leicester screening programme, which tested 4004 migrant patients, revealed new diagnoses of TB, Hepatitis B and C, and HIV.
Researchers developed LUCAS, a rapid and portable diagnostic tool that creates stronger and longer-lasting bioluminescence signals, enabling accurate detection of SARS-CoV-2, HIV, HBV, and HCV in patient samples. The tool achieved an average accuracy of over 94% in detecting viruses within 23 minutes.
A recent study found that persistent Wnt signaling affects IVF embryo implantation and offspring metabolism. The researchers discovered that treating with the Wnt inhibitor IWP2 improves implantation, intrauterine development, and offspring metabolic abnormalities.
Professor Zhou's research project FoCo aims to improve the efficiency of optimizers used in large AI models, reducing high training costs and memory usage. The study has potential real-world benefits in dynamic environments such as self-driving cars, enabling faster deployment of safer and more responsive AI systems.
The American Heart Association condemns Big Soda's lawsuit against Santa Cruz's sugary drink tax, citing the industry's profits over health. The organization supports the city's efforts to curb sugary drink consumption and protect public health.
This book sheds light on <em>d</em>ōchō atusryoku</em>, a defining force in Japanese society that shapes politics, governance, and the legal system. It also explores how social conformity influences behavior through expectations rather than laws.
A new study by University of Cologne researchers found that teaching 'threshold concepts' like randomness and probability in a biological context improves students' understanding of biology. The study suggests that addressing these concepts can increase the complexity and coherence of concept networks.
Researchers from Mass General Brigham will present breakthroughs in cancer treatment, including an update on the INCIPIENT trial using CAR-T cells for glioblastoma. The team also developed a psychosocial digital application to support caregivers of patients undergoing hematopoietic stem cell transplantation.
A new app, BMT-CARE App, was tested in a randomized clinical trial to help caregivers manage stress and emotions related to bone marrow transplant patients. The app showed significant improvements in quality of life, burden, and mood symptoms compared to standard services.
Researchers studied obesity's impact on breast cancer, linked imaging patterns to lung disease survival, and tracked hidden inflammation in COVID-19 patients using advanced PET imaging techniques.
A new study reveals that singing to infants significantly improves their mood, reducing fussiness and stress. By incorporating music into daily routines, parents can create a positive environment for their baby's emotional development.
Researchers demonstrate a new strategy for magnetization reversal in multiferroic materials, allowing for more energy-efficient electronics. The study achieves this breakthrough by growing thin films in an unconventional crystallographic orientation, enabling the application of electric fields perpendicular to the film surface.
A team of NYU researchers created an automated modeling tool to estimate 311 under-reporting of heat and hot water problems in city buildings. The study found that some neighborhoods and addresses report problems at lower rates than others, leading to potential under-reporting of these issues.
Patients with breast cancer detected through routine screening mammography have improved clinical outcomes, including lower odds of advanced stage breast cancer and death. In contrast, symptom-detected cases were more frequent in older women and had higher mortality rates.
Gene editing technologies could enable climate-resilient crops, higher yields, and reduced fertilizers and pesticides. Researchers advocate allowing gene editing in organic farming to support the EU's goal of 25% organic agriculture by 2030.
A recent study using SWOT satellite data has revealed the existence of powerful submesoscale eddies in the ocean, which play a significant role in shaping the climate system. These smaller currents carry surprisingly large amounts of energy and influence marine food webs, weather patterns, and events like El Niño and La Niña.
A new model details the kinetics of exciton dynamics in OLED materials, enhancing lifetime and accelerating material development. The findings have potential to improve fluorescence efficiency, leading to more advanced OLED devices.
Researchers at Rutgers and Brookhaven National Laboratory have developed tools that can capitalize on metacaspase 9's ability to help plants combat a wide range of diseases. The enzyme plays a crucial role in programmed cell death, which is essential for fighting diseases and responding to stress.
The American Cancer Society estimates that 18.6 million people in the US live with a history of cancer as of January 1, 2025, and this number is projected to increase to over 22 million by 2035. The study highlights notable disparities in treatment for common cancers, including lung and colorectal cancer.
Researchers developed an advanced single-cell sorting platform that dramatically shortens the screening process for identifying high-value microbial strains. The technology enabled the isolation of a mutant strain producing 58% more DHA than the wild type in just two days.
The University of Exeter has unveiled a new Handbook providing practical guidance for states to develop or review their national positions on international law and cyber activities. The 176-page guide offers concrete and accessible steps for government lawyers, policy officials, academics, and experts in this rapidly evolving field.
Researchers at Tohoku University developed a novel strategy to modulate spin states of single-atom catalysts using external magnetic fields. This approach improves electrocatalytic performance by reducing activation energy and increasing reaction rates.
New University of Michigan studies find that women primary care physicians are more likely to experience burnout from patient portal messages, but also spend more time managing these messages. Innovative solutions like Patient Asynchronous Care Effort (PACE) slots can help reduce workload and improve physician experiences.
Researchers used anonymized GPS data from smartphones to monitor how wildlife reacts to people, highlighting the potential of human mobility data in tracking human-wildlife conflicts. The study's findings can inform conservation planning, help protect animals and wild spaces, and ensure that recreational activities are done responsibly.
A historical overview of Singapore's edible gardens sheds light on the British colonial government's Garden City Movement and its impact on urban wellbeing. The research also explores the role of vernacular gardening in Singapore, particularly during the Japanese Occupation, where food shortages led to mandatory tapioca-planting.
Researchers found cardiac deaths exceeded expected levels between 2020 and 2023, with a significant increase in 2020 and 2021. The study suggests potential shortcomings in cardiac care during and after the pandemic.
Researchers from Florida Atlantic University have discovered a potentially safer treatment for multiple disorders linked to altered dopamine signaling by blocking the kappa opioid receptor. The study found that this approach can correct behavioral deficits and normalize dopamine availability.
A cohort study of 4 countries found that both maternal and paternal higher education levels were linked to reduced cognitive decline, with own education mediating these associations. The study highlights the long-term impact of parental education on offspring cognitive health across diverse cultural contexts.
The Routledge Handbook of Men's Victimization in Intimate Relationships offers a comprehensive international synthesis of this topic. The book highlights where current systems fall short and prescribes changes needed for male IPV victims, drawing on research from 31 contributors across five continents.
A new NYU study suggests that experiences with discrimination, racial inequality, and police violence may contribute to the development of psychosis in low-income young adults of color. The research found a higher incidence of psychotic episodes among Blacks, Latinos, and Indigenous respondents compared to white respondents.
Chinese researchers developed a groundbreaking 3D genome mapping technology that reveals how the 3D organization of plant genomes influences gene expression, especially in photosynthesis. The innovation provides a precise tool for understanding long-range chromatin interactions and their role in regulating biological processes.
A research team at DGIST developed an algorithm that allows inexpensive sensors to detect transparent obstacles like glass walls. The probabilistic incremental navigation-based mapping (PINMAP) algorithm accumulates rare point data and calculates the likelihood of glass wall presence, achieving detection performance comparable to expen...
A CU Anschutz study identifies a genetic variation in the GLP-1R gene that may explain why some children exposed to gestational diabetes become obese, while others don't. The study found that children with this variation gained weight faster and had higher BMI compared to those without.
Researchers from Japan conducted a cross-cultural analysis to compare mentalizing difficulties in British and Japanese autistic and non-autistic adults. They found that Japanese autistic participants outperformed both groups of British participants, suggesting cultural differences in interpreting social cues.
Researchers discovered a specialized histone arrangement, called the CENP-A–H4 octasome, in centromeric regions. This unique structure likely contributes to proper kinetochore formation and mitosis.
A common genetic variant has been found to double the risk of dementia in men, but not women, according to new research. The study, published in Neurology, used data from the ASPirin in Reducing Events in the Elderly (ASPREE) trial to investigate the link between the HFE gene variant and dementia risk.
In an international clinical trial, a new CAR-T cell immunotherapy demonstrated promising results against aggressive blood cancers, including T cell acute lymphoblastic leukemia and T cell lymphoblastic lymphoma. Most patients who received the full dose of cells achieved full remission, with response rates ranging from 70-90%.
A team of researchers analyzed a photosynthetic complex found in a marine alga and discovered a unique arrangement of antenna proteins around the photosystem core. This structure indicates an adaptation to its living environment and provides insights into the efficiency of light-harvesting under certain conditions.
Researchers at Ohio State University have developed blood tests to diagnose pancreatic cancer and predict treatment outcomes. Genetic information can also help predict breast cancer survival rates, while a new blood test may improve treatment response for patients with advanced sarcoma. These findings offer promising tools for early de...
A new study finds that bats are a reservoir for morbilliviruses, including the human measles virus, and can transmit them to other mammalian species, such as monkeys. The research suggests that these viruses have crossed species boundaries multiple times, posing a significant threat to human health and livestock.
Research reveals Akkermansia muciniphila consists of four distinct subtypes competing for colonization. A specific subtype secures its position by selectively eliminating competitor cells through extracellular vesicles.
A 48-month study found that intensive blood pressure reduction lowered the risk of dementia and cognitive impairment by 15% and 16%, respectively. This suggests that reducing high blood pressure may be a key strategy for preventing dementia in patients with hypertension.
A Phase III trial led by MD Anderson Cancer Center demonstrates a triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improves progression-free survival and overall survival in BRAF V600E-mutated metastatic colorectal cancer. The regimen offers a clear survival advantage over standard chemotherapy alone.
The AADOCR SCADA/Dentsply Sirona Research Award aims to support early-stage dentist-scientists by providing up to $10,000 for research projects and infrastructure establishment. The award's recipients must submit a report within 12 months of receiving the funding.
A recent study found that eliminating fluoride from public water systems would substantially increase dental decay and related costs, particularly for publicly insured and uninsured children. The researchers estimated a 7.5 percentage point increase in tooth decay and $9.8 billion in additional dental care costs over five years.
A pilot study found that the Mediterranean diet provided symptom relief for patients with irritable bowel syndrome (IBS), with 73% of participants experiencing improvement. The low FODMAP diet was also effective but led to greater improvements in abdominal pain intensity and IBS severity score.
Four new studies provide conclusive evidence for the existence of intermediate-mass black holes, offering a window into the universe's first stars. The researchers used data from LIGO detectors to identify these heavy gravitational-wave events, paving the way for future observations using space-based missions like LISA.
Researchers at National University of Singapore develop a new method to analyze large-scale metabolomic data, revealing meaningful patterns associated with metabolic change. The framework enables stratification of individuals based on their metabolic profiles and associated disease risks.
Global soil nitrous acid emissions have increased from 1980 to 2016, contributing to a 2.5% annual rise in the global surface ozone mixing ratio. This can lead to overexposure of vegetation to ozone, affecting ecosystem balance and food crop production.
A new study by Yale University scientists suggests that mangroves are more resilient than expected to intense and frequent storms due to climate change. The 'recovery debt' measure indicates that mangroves can recover from the loss of carbon during storms within four years, providing a valuable sink for carbon.
Researchers identified specific antibody features that limit Mtb growth, revealing critical insights into antibody-immune cell interactions. The study lays groundwork for potential antibody-based therapies or vaccines against tuberculosis, an urgently needed treatment for the deadly infectious disease.
A new Phase 2 clinical trial at UC Davis Comprehensive Cancer Center unveiled clues as to why patients with aggressive prostate cancer are doing poorly and may offer hope in the form of targeted therapy. The study showed the potential of using genetic testing and blood-based monitoring to better understand and track prostate cancer.
A NIH-funded study has identified trans-epidermal water loss as a reliable predictor of diabetic foot ulcer recurrence. Participants with high TEWL were 2.7 times more likely to experience wound recurrence, highlighting the importance of skin barrier function in wound healing.
A study reveals PD-1 is a deeply conserved feature across jawed vertebrates, with its discovery in sharks and bony fishes indicating immune restraint via PD-1. Key findings include well-conserved hydrogen bonds between PD-1 and PD-L1, and a conserved role for PD-1 as an immune checkpoint.
The study identifies hierarchical structures and complex interlayer interactions in trilayer graphene systems, offering a promising new solid-state platform for programmable quantum devices. Researchers develop a 'structural phase diagram' to guide future design of quantum materials using multi-moiré lattices.
The combination of dual-targeted therapies with encorafenib and cetuximab plus chemotherapy significantly improved outcomes in previously untreated patients with metastatic colorectal cancer, doubling overall survival. Improved progression-free survival was also observed, reducing the risk by 47%.
A study combines DFT and machine learning to analyze a wide range of epoxides in CO₂ cycloaddition, identifying key molecular descriptors and predicting reactivity trends. The research aims to develop predictive catalyst and substrate design for optimized CO₂ fixation, contributing to greener chemical processes.
Researchers have developed a sustainable method for extracting sugars, organic acids, and phenolic compounds from corn stover using subcritical water. This process recovers high-value bioderivatives with yields up to six times higher than traditional methods, reducing energy costs and time.
The Late Ordovician Mass Extinction was caused by the rapid onset of global warming after the Hirnantian glaciation. The extinction lasted approximately 400 kyr with an average species extinction rate of 71.6% per 100 kyr during this period.
A study by Associate Professor Chang Pao-Li explores how trade shocks propagate through firm-to-firm linkages, affecting productivity, labor demand, and innovation. The research aims to quantify the positive effects of multinational enterprises on local economies, including increased labor demand and higher wages.
Researchers have discovered that blow flies can detect forces with high sensitivity, not only magnitude but also rate of change, which is crucial for balance and locomotion. The study's findings have promising implications for the design of next-generation walking robots.
A team of researchers at Texas A&M University has received a $1.6 million grant to develop a system for rapidly accelerating the certification process of 3D-printed critical components used in military applications.