Researchers are seeking 450 participants to explore the health effects of adopting a vegetarian or vegan diet among younger adults with overweight or obesity. Over 12 months, participants will follow a plant-based diet and have regular health checks to measure their health outcomes.
Scientists have discovered a 518-million-year-old fossil named Urokodia, which shows the earliest evidence of spiders' fangs. The fossils revealed two pincer-like limbs emerging behind the eyes, marking the beginning of chelicerae. This discovery sheds light on the origin of spider bites and book gills in the Chelicerate family.
A new clinical trial, SELECTmeso1, is investigating a personalized treatment for patients with a rare and aggressive form of cancer. The trial aims to improve outcomes for patients with a specific genetic biomarker, and if successful, could lead to future practice-changing trials.
A landmark trial is underway to test new treatments that restore the body's natural warning signs for low blood glucose in people with type 1 diabetes. The CLEAR trial compares innovative treatments, including an artificial pancreas system and bespoke psychoeducational programs, to find the most effective way to prevent severe episodes.
A new study found that walking pace is a strong predictor of mortality risk, especially in people with existing health conditions. Combining walking pace with other physical measures improved mortality predictions, suggesting a simple and cost-effective way to identify high-risk individuals.
A groundbreaking study found that frail men have a significantly higher risk of dying within one year after a heart attack, challenging the prevailing narrative that high clinical risk is predominantly a female issue. The research highlights the need for sex-informed care pathways to address this disparity.
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
A study published in EBioMedicine found changes in blood samples from almost 1,000 people hospitalized for COVID-19 may pinpoint patients at risk of long-term lung disease. The study identified elevated levels of certain molecules, which could lead to the development of simple blood tests to detect ongoing lung problems.
A new study has identified unique protein signatures linked to ethnicity and changes in physical activity, which may influence cardiometabolic health. The research found that South Asian individuals may face a higher risk of cardiometabolic disorders due to distinct immune, inflammatory, and metabolic pathways.
Researchers have created a design framework for magnetic cloaks that can protect sensitive electronics and sensors from magnetic interference. The new concept enables shielding of components in fusion reactors, medical imaging systems, and isolating quantum sensors.
The Ketton mosaic in Rutland depicts an alternative telling of the Trojan War, based on a lesser-known tragedy by Aeschylus. The research reveals that Roman British craftsmen were part of a wider network of trades passing design patterns down generations.
The University of Leicester, in partnership with TWI Ltd, has secured £560k to develop a robot-mounted arc-welding system for in-space repair and manufacturing. The project aims to overcome the challenges of welding in space by developing a new, space-qualified robotic welding capability.
A new study by the University of Leicester reveals that Africa's forests have switched from absorbing to emitting carbon, with approximately 106 billion kilograms lost per year between 2010 and 2017. This alarming shift underscores the urgent need for stronger global action to protect forests.
Researchers have identified a distinct type of frailty in younger people driven by cardiovascular and metabolic illnesses, leading to poor outcomes and premature death. The study calls for routine frailty assessments in all heart attack patients, regardless of age.
A European consortium developed a new decision-making framework to predict COPD exacerbation severity and prognostic risk, integrating three key factors: baseline health status, event intensity, and triggers. This framework, known as BAt model, aims to guide treatment strategies and improve consistency across clinical settings.
Scientists aim to understand the impact of microgravity on human physiology and develop strategies for safe space travel. The Fluorescent Deep Space Petri-Pod experiment will deploy nematode worms in space to study their behavior and health.
Scientists have discovered a protein called SCEP3 that ensures even chromosome segregation in plants, preventing infertility and genetic diseases. This finding has implications for plant breeding and understanding human fertility, with the equivalent gene SIX6OS1 potentially playing a role in promoting correct chromosome segregation.
A new AI-based risk assessment tool, GRACE 3.0, has shown better predictability of future risk for heart attack patients compared to traditional methods.
A new study published in Diabetes, Obesity and Metabolism found that weight loss treatments, including medication and surgical procedures, may help lower the risk of obesity-related cancers in people with obesity and type 2 diabetes. The study analyzed data from over 180,000 people and found a significant reduction in cancer incidence ...
A University of Leicester-led study reveals that around one in three hospital infections involve antimicrobial resistance, independently associated with a higher risk of death. The study found patients with resistant infections had a 58% increased risk of mortality compared to those with susceptible infections.
Researchers have identified over 120 genetic signals shaping foveal development, including pathways involved in vitamin A metabolism and retinal cell fate. The study provides the first comprehensive genetic dissection of human foveal pit architecture, revealing new insights into childhood visual disorders.
Two baby pterosaurs, aged less than 20 cm with broken wings, were found to have died from powerful storms that also preserved hundreds of other fossils. The discovery explains why smaller fossils are well-preserved, as they were a direct result of storms.
Researchers are collecting faeces from exotic animals at Dudley Zoo and West Midlands Safari Park to search for phages that can fight bacterial infections. The goal is to create a bio-bank of these phages to develop alternative treatments for life-threatening infections.
A genetic test developed by Dr Lauren Lansdowne can reliably determine the species of individual gibbons, helping to preserve vulnerable populations. The test uses DNA sequencing and has been validated using large-scale samples from over 200 gibbons in European zoos.
Scientists at the University of Leicester discovered that jewel wasps can slow down their biological rate of ageing by undergoing a natural 'time-out' as larvae. This pause in development extends lifespan and decelerates the epigenetic clock, tracking chemical changes in DNA.
A new genetic study has identified genes involved in neuronal signalling and sensory pathways as key drivers of chronic cough. The findings advance our understanding of cough reflex hypersensitivity as a nervous system-mediated process, opening up opportunities for targeted treatments.
A new Leicester study found that women with type 2 diabetes are nearly twice as likely as men to have hidden heart damage, according to researchers. The study used advanced MRI scans and data from four studies conducted at the NIHR Leicester Biomedical Research Centre.
University of Leicester researchers analyzed coral cores to spot the start of industrial deforestation in Malaysian rainforest and its impact on coastal ecosystems. The study found that sediment concentrations remained low before 1950, but increased after, indicating enhanced soil erosion due to deforestation.
The University of Leicester's Space Park Leicester is designing a Double-Walled Isolator (DWI) to safely store and analyze extra-terrestrial materials, including Martian samples. The project aims to provide a high-level of containment and cleanliness to avoid cross-contamination.
Scientists from University of Leicester collaborate with traditional Amazonian communities to monitor biodiversity using artificial intelligence, enabling them to maintain control over their resources and territories. The project aims to reshape conservation approaches in the world's largest tropical rainforest.
A new study found that routine testing for multiple infectious diseases among migrants can identify key infections earlier, improving health outcomes and reducing onward transmission. The Leicester screening programme, which tested 4004 migrant patients, revealed new diagnoses of TB, Hepatitis B and C, and HIV.
Researchers at the University of Leicester have developed a technique using soundwaves to separate valuable catalyst materials and fluorinated polymer membranes from catalyst-coated membranes. This breakthrough addresses critical environmental challenges posed by PFAS, which contaminate drinking water and have serious health implications.
A study by the University of Leicester has successfully linked fossilised footprints to distinct groups of pterosaurs, shedding light on their lifestyles and behaviors. The discovery supports the idea that pterosaurs underwent a major ecological shift during the middle part of the Mesozoic era.
The University of Leicester and NASA's Glenn Research Center have successfully combined cutting-edge radioisotope power system technology with high-efficiency power convertor technology, demonstrating a new breed of space nuclear power systems.
A new species of multisegmented fossil has been discovered in the Soom Shale with exceptionally preserved insides, including muscles, sinews, and tendons. The fossil, named Keurbos susanae, provides a unique glimpse into the evolutionary relationships of ancient arthropods.
Scientists have captured the first detailed molecular movie of DNA being unzipped at the atomic level, revealing how cells copy their genetic material. The discovery has significant implications for understanding viral and cancer replication.
Scientists suggest that wind turbine blades will fossilize into the far future due to their composition of fibreglass and epoxy resin. These relics will provide a unique puzzle for future paleontologists to reconstruct and understand the human-made technology behind them.
Researchers at the University of Leicester have created a technique to extract valuable metals from battery waste using a mix of water and cooking oil. The process enables the recovery of battery-grade metal oxides at room temperature, leaving behind 'black mass' that can be skimmed off to produce pure metal oxides.
Researchers from University of Leicester identified genetic variants linked to successful smoking cessation using varenicline. The study sheds light on the biological processes involved in responding to the drug.
A large UK-wide study has identified specific clusters of long-term health conditions associated with lower quality of life, particularly those linked to chronic pain, depression, and cardiovascular disease. The findings highlight the need for tailored treatment approaches for patients with multiple long-term health conditions.
A multidisciplinary team of researchers will investigate how animals detect magnetic fields, building on existing knowledge that a blue-light sensing protein called Cryptochrome plays a key role. The study's findings may lead to the development of non-invasive measurement tools and magnetic cell therapies.
University of Leicester researchers use UV torches to reveal tiny details distinguishing Pterodactylus from other fossils, uncovering nearly 50 'hidden' relatives and reconstructing its life history from hatchling to adulthood.
A UK study published in Diabetic Medicine found that over half of pregnant women with gestational diabetes were undiagnosed due to slow NHS blood test processing. Faster blood processing identified additional cases, leading to improved health outcomes for mothers and babies.
Scientists reveal that the Antarctic ice sheet is more unstable than previously thought, with periods of sudden melting linked to changes in Earth's orbit. The study provides a glimpse into the potential behavior of Antarctica without the Greenland Ice Sheet, highlighting the urgent need for climate action.
Mathematicians at University of Leicester applied statistical mechanics to detect human-made and natural causes of climate change, enabling early warnings of potential disasters. The theory provides a more advanced understanding of climate mechanisms driving change.
A recent study published in Nature Sustainability analyzed global forest disturbance patterns from 2002 to 2014, identifying four main types of patches and mapping their distribution across different biomes. Human activities tend to leave similar patterns globally, with potential implications for forest resilience.
The University of Leicester is collaborating with NASA to develop a novel Radioisotope Power System design and conduct laboratory tests. This collaboration aims to improve the efficiency of electrically heated simulators and Stirling convertor technologies, enabling spacecraft to venture into new frontiers. The project builds on previo...
Researchers at University of Leicester developed a comprehensive fungal spore calendar to help patients manage symptoms through seasonal awareness. The study found two main peaks in spore concentrations: one in the summer and smaller peak in autumn, influenced by temperature and rainfall.
A new £5.5 million research unit will strengthen existing UK systems to measure environmental exposures and understand how they affect the body. The Health Protection Research Unit in Chemical Threats and Hazards aims to develop new technologies to detect chemicals in emergency situations.
Researchers discovered that tuberculosis alters liver metabolism and can push patients towards metabolic disease like diabetes. The study suggests undiagnosed TB could be a significant contributor to metabolic health issues.