A new study has identified ADAR1 as a key factor in suppressing the immune response triggered by lenalidomide, leading to drug resistance in multiple myeloma. The research suggests targeting ADAR1 and the dsRNA pathway could offer promising strategies to overcome resistance.
A systematic review of platform supply chain logistics service strategies reveals the importance of service cost and level in choosing between self-built and third-party logistics. Shared logistics sharing also offers an innovative resource-sharing model with multiple companies.
A new study explores ultra-high-speed machining, revealing that high-performance materials pose challenges such as low efficiency and rapid tool wear. The researchers identify three typical material removal mechanisms: ductile-mode, brittle-mode, and extrusion removal, with the latter having a broader range of applicability.
The journal Engineering is soliciting nominations for the 2025 Top Ten Global Engineering Achievements, honoring groundbreaking engineering accomplishments with significant global impact. Eligible entries include completed major projects, technological equipment, or breakthroughs in core engineering innovations across various fields.
Researchers explored cyclic CO2 injection in unconventional reservoirs, finding a 3.4% increase in oil recovery and 48.3% of injected CO2 stored underground after ten cycles. However, this process reduced cumulative oil production by 2.2%.
A breakthrough in medical technology, the wearable stethoscope accurately monitors lung sounds in real-time and detects wheezing. An AI-based algorithm classifies breathing sounds and counts wheezing events with high accuracy.
A recent study presents a novel approach to optimizing peer-to-peer coupled electricity and carbon trading among prosumers. The proposed framework achieves optimal electricity–carbon P2P trading, outperforming traditional market schemes in terms of economic benefits and carbon-emission reduction.
Scientists at Virginia Tech have developed a method to produce, store, and deliver exosomes containing wound-healing compounds for targeted drug delivery and diagnostics. The breakthrough process improves stability for up to a year at room temperature, enabling mass production and commercial implementation.
Researchers investigate microbial reduction of vanadate to detoxify the environment. Electron transfer pathways, including extracellular and intracellular processes, are identified as crucial for vanadium detoxification. Vanadium isotope fractionation also follows a Rayleigh model, with lighter isotopes reacting preferentially.
A study found that pharmacists with high assertiveness tend to reduce the number of prescribed medications, especially in elderly patients. The research suggests that improving pharmacists' communication skills could lead to safer drug treatment and better health outcomes.
Researchers developed an equation describing pressure wave propagation in bubbly flows, confirming that changes in tube cross-sectional area contribute to pressure wave attenuation. The rate of change in tube cross-sectional area is a key parameter governing pressure wave attenuation.
A new plant tissue has been discovered in plants essential for seed formation, which can increase crop yields. The 'Kasahara Gateway' structure functions as a gateway and is regulated by a gene called AtBG_ppap.
A systematic review of nearly 6000 runners found that lower energy and fat intakes were strongly associated with a higher risk of injury in female runners. A low-fibre diet also increased the likelihood of bone stress injuries.
Prolonged sitting impairs forearm cutaneous vascular function, but alternating local skin cooling and heating alleviates this effect. This study found that ambient temperature modulation can mitigate the decline in cutaneous vascular function.
Kyushu University researchers have successfully recreated the fluid dynamics of flowing biological cells using numerical simulations. The study reveals that capsule position depends on deformation and pulsation frequency, enabling precise cell manipulation in research and potential applications in artificial heart development.
Researchers introduce Debye relaxation into metamaterials, bridging the gap between dielectric physics and metamaterial design. The model enables broadband electromagnetic parameter regulation, opening new dimensions for dispersion control.
A recent study from Dalian Institute of Chemical Physics measures surface charges in liquid environments, revealing an additional driving force that pulls photogenerated electrons to the surface. The researchers also found that local surface potential varies with pH and identified an optimal pH range for efficient charge transfer.
The paper proposes a new safety concept based on system-of-systems (SoS) perspective to address challenges in civil aviation transportation system (CATS) safety management. The SoS safety concept includes three core elements: safety capability, safety logic, and safety architecture.
A fully automated ICSI system has successfully conceived the world's first baby, promising to transform fertility treatment with greater standardization and consistency. The system, developed by Conceivable Life Sciences, uses AI to position sperm cells and execute microinjection with unprecedented accuracy.
A study of 27 projects educating marginalized girls in lower- and middle-income countries finds that community mobilization is key to sustainable change. The projects, which worked with local influencers and empowered young women, laid the foundations for lasting progress by challenging entrenched social norms.
Researchers at CNR-INO observed capillary instability in an ultradilute quantum gas, creating a new form of matter with potential implications for industrial and biomedical applications. The study, published in Physical Review Letters, involved the use of imaging and optical manipulation techniques to create and analyze quantum droplets.
The ATLAS Collaboration has made significant contributions to particle physics, including detailed measurements of Higgs boson properties and studies of rare processes. Mainz researchers have played a key role in the construction and operation of the detector, making numerous leading contributions to the collaboration.
A new clinical trial at the University of Miami Miller School of Medicine is testing a novel combination of immunotherapy drugs and an oncolytic virus to treat high-grade neuroendocrine cancer. The trial aims to find safe combination doses and compare effectiveness with standard-of-care treatment.
Researchers have found evidence of a new population of faint galaxies hidden in the far-infrared sky, which could break current models of galaxy numbers and evolution. The discovery was made using data from the Herschel Space Observatory, which revealed a deeper image of the universe than ever before.
Fiddler crabs use vibrational signals to communicate during courtship, and a new study reveals that signal features are influenced by the male's claw size. Researchers found that males with larger claws produce higher-energy signals, allowing females to assess their quality from afar.
Researchers analyzed ancient stone tools found in the Robberg caves, revealing specific methods of core reduction that indicate shared ideas among prehistoric people. The study suggests that these ancient humans were more connected than previously thought, with similar tool-making techniques found across different regions.
New research suggests that conservation efforts can better protect bird species at greatest risk from climate change by understanding the specific climatic conditions they need to thrive. The study found that species with narrower climatic niches are more susceptible to population declines.
A study by the Barcelona Institute for Global Health found that Europe has adapted better to cold temperatures than to heat over the last two decades. The relative risk of death in low temperatures decreased by 2% per year, while the risk from extreme heat fell by 1% per year.
Research reveals that certain types of nasal bacteria can affect protein levels in the respiratory tract, increasing vulnerability to COVID-19. The study identified three common bacteria linked to higher expression levels and increased risk, while another type may offer protection.
A phase 1 clinical trial will evaluate the safety and efficacy of CLBR001 + SWI019 in patients with myositis, systemic sclerosis, lupus and rheumatoid arthritis. The therapy has the potential to reduce side effects and patient burden associated with traditional CAR-T approaches.
The partnership will focus on advanced simulations, high-energy particle generation, and artificial intelligence to optimize data management in laser facilities. This collaboration aims to promote innovative technologies for nuclear fusion energy production through high-power lasers, advancing scientific knowledge in the energy sector.
Research reveals thousands of chemical compounds derived from coral reefs and seaweeds are available for microbial decomposition and utilization. Microbes can break down previously thought-to-be-harder-to-degrade chemicals, such as benzene rings and steroids.
A new study found that mesenchymal stem cell-derived extracellular vesicles significantly enhance survival and facilitate substantial peripheral blood recovery in mice exposed to high-dose irradiation. The treatment promoted hematopoietic recovery, with increases in red blood cell, platelet, white blood cell, and hemoglobin levels.
A six-month study found that patients using GLP-1 and dual GLP-1/GIP receptor agonist therapy experienced minimal lean muscle mass loss as they lost weight. Regular resistance training, consistent protein intake, and close supervision by an expert obesity doctor were associated with better muscle retention.
A new study published by the American Academy of Neurology found that having a father with Alzheimer's disease may be associated with a greater spread of tau protein in the brain. Female participants also showed a heavier buildup of tau protein, highlighting potential vulnerabilities.
RMIT University's PYROCO technology converts treated sewage into a carbon-rich product called biochar, which acts as a catalyst to produce phenol-rich bio-oil. The technology has been applied to several circular economy applications and offers a sustainable way to reduce carbon dioxide emissions.
Researchers at NYU Tandon School of Engineering developed a method to directly predict visible content in immersive 3D environments, reducing bandwidth requirements by up to 7-fold while maintaining visual quality. The technology has the potential to make AR/VR experiences more responsive and accessible.
A new study found that both employed people with obesity and employer representatives acknowledge the impact of obesity on future health problems and perceive lifestyle change alongside anti-obesity medications as the most effective approach for maintaining weight-loss reduction. Cost of medication coverage remains a significant barrie...
Researchers from Rutgers University mapped mercury contamination in penguins of the Southern Ocean, revealing variations in mercury accumulation among different species. The study found that Adelie and gentoo penguins had low mercury levels, while chinstrap penguins showed significantly higher exposure due to their migration patterns.
Researchers have mapped hundreds of thousands of neurons in the mouse brain, revealing complex connections between cells and their firing patterns. This breakthrough could help understand how our brains process visual information and potentially guide treatments for brain disorders.
Dr. Wei Li is creating a virtual lunar welding platform to simulate welding in the moon's harsh environment, addressing temperature fluctuations and extreme vacuum conditions. The project aims to enable reliable large structure assembly on the moon, a crucial step for human colonization.
Researchers monitored daily wastewater concentrations of multiple viruses at five sites in the UK, revealing links with site-specific reported events. The findings suggest that near-source wastewater monitoring could benefit local communities and provide earlier warnings of wider trends.
Scientists have built a digital twin of the mouse brain's visual cortex using AI, predicting neural activity and anatomical features. The model can generalize to new visual inputs and data, speeding up brain research and understanding intelligence.
A Rutgers University study found that higher firearm violence in neighborhoods is associated with lower rates of people going to the dentist and higher rates of total tooth loss. Chronic exposure to violence can lead to fear, stress, and unhealthy behaviors that impact oral health.
A study published by the American Academy of Neurology found that heavy drinkers have an increased risk of brain lesions and signs of brain injury, including hyaline arteriolosclerosis and tau tangles. Heavy drinking was also associated with lower brain mass ratio and worse cognitive abilities.
Compositional rock anomalies within oceanic plates caused by ancient tectonics influence the trajectory and speed of subducting plates. The findings provide a greater understanding of plate subduction, recycling surface materials deep into the Earth's interior.
A comprehensive atlas of gene activity in chickens has been created, revealing how millions of genetic variants affect gene regulation and giving researchers tools to understand agriculturally important traits. This knowledge could lead to healthier flocks, more resilient farming systems, and fewer economic losses for poultry producers.
The article discusses how 3D printing technology is transforming the production of microelectronic and microfluidic devices, enabling complex structures with unparalleled precision. The study highlights the potential of 3D printing in various applications, including sensors, actuators, and flexible electronics.
Researchers created a promising approach that augments LLMs with graph-based models to generate molecules with desired properties. The method generates molecules with better matching user specifications and valid synthesis plans, outperforming existing LLM-based approaches.
The discovery of Jurassic fossil acanthocephalan Juracanthocephalus provides crucial reference for understanding evolutionary innovations and body plan of thorny-headed worms. It suggests that acanthocephalans may have originated in terrestrial environments and diverged from Rotifera no later than the Middle Jurassic.
A new study by the University of Oulu has directly observed the merger of star clusters in dwarf galaxies for the first time, shedding light on their formation. The observations confirm that compact star clusters form through the cannibalization of smaller globular clusters at the centers of these galaxies.
Researchers at Florida Atlantic University developed an innovative real-time ASL interpretation system using AI and deep learning. The system achieved a 98.2% accuracy rate with minimal latency, enabling fast and reliable performance for applications such as live video processing and interactive technologies.
A new amplifier developed by Chalmers University of Technology can transmit ten times more data per second than current systems, holding significant potential for various critical laser systems, including medical diagnostics and treatment. The amplifier's large bandwidth enables precise analyses and imaging of tissues and organs.
A new analytical method has been developed to measure plasma P-tau217, a blood-based marker that can change several years before Alzheimer's symptoms appear. The fully automated method demonstrated high accuracy of over 90% in various settings, including primary care and specialized memory clinics.
Tulane University scientists developed a handheld device to deliver rapid and accurate tuberculosis diagnoses in under an hour. The device, called the lab-in-tube assay (LIT), can detect Mycobacterium tuberculosis DNA in saliva, blood, and sputum samples, offering a cost-effective tool for improving TB diagnoses in resource-limited areas.
Researchers found that victims of knowledge theft become more protective and territorial about their work, leading to a toxic environment. Organizations must confront and prevent knowledge theft by rewarding teams as a group and promoting the sharing of knowledge.
Researchers developed an in-situ EPR setup to accurately identify radicals generated by PAA activation under different UV wavelengths, revealing distinct radical generation pathways. The study provides new insights into the mechanisms of radical formation and transformation using density functional theory calculations.
Researchers developed a novel approach to visualize and analyze driving behaviors in electric vehicles, revealing the impact of driving patterns on energy consumption. Key findings show that rapid acceleration is a primary cause of excessive energy consumption, which can be mitigated by adopting eco-driving behaviors.
A study published in ACS Journal of Agricultural and Food Chemistry found that starch-based microplastics can cause liver damage, gut microbiome imbalances, and circadian rhythm disruptions in mice. Researchers suggest further research is needed to understand the effects of these biodegradable particles.
New research found pet dogs disturb and directly harm wildlife, even when leashed, leading to reduced animal activity and avoided areas. Dog waste contributes to water pollution and inhibits plant growth.
A University of Ottawa-led research team has deciphered the message that serotonin conveys to the brain, discovering a 'prospective code for value' that explains why neurons are activated by rewards and punishments. This finding has implications across multiple fields, including neuroscience, psychology, and psychiatry.
Researchers identified CSC characteristics, endogenous regulatory mechanisms, niche factors, and targeting strategies for digestive system tumors. Understanding CSCs is crucial for developing breakthrough treatments.
Researchers have initiated a clinical trial using an investigational medicine to lower amyloid precursor protein, targeting Alzheimer's disease in adults with Down syndrome. The study aims to prevent the development of Alzheimer's disease by addressing its underlying genetic cause.
A new study proposes a third category of galaxies: red star-forming. These galaxies produce low-mass stars and may have played a significant role in the universe's history. The findings could change our understanding of galaxy evolution, star formation, and the life cycle of galaxies.
Applications are now open for the 2025 EurekAlert! Travel Awards for International Science Reporters, offering travel funding to attend the 2026 AAAS Annual Meeting. Early-career science journalists from Brazil and Eastern European countries can apply through May 5, 2024.
A new genomic study has uncovered long-lost genetic diversity in mammoth lineages spanning over a million years, shedding light on their evolutionary history. The findings demonstrate the power of ancient DNA in characterising past genetic diversity and advance our understanding of mammoth evolution.
The authors propose expanding psychological contract theory to include non-human agents, such as algorithms, in digital labor platforms. They analyze how workers form contracts with these agents and explore the implications for understanding digitalized working relationships.
Researchers have created a flexible and tunable infrared stealth technology by adjusting the phase change material GST in different states. The metafilm achieves effective infrared stealth functionality in certain atmospheric window bands and excellent radiative heat dissipation capabilities in others.
Researchers have identified Tim-3 as a promising therapeutic target for Alzheimer's disease by targeting microglia in the brain. Deleting Tim-3 helps kickstart plaque removal, reduce neuroinflammation, and limit cognitive impairment.
A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new research. The study suggests new avenues for drug development to reduce the risk of developing both diseases by targeting alpha-synuclein.
Researchers have discovered a new way to characterize terahertz quasi-bound states by inducing abrupt lateral beam shifts. These shifts can be controlled and potentially used in next-generation sensors and wavelength division multiplexers.
The WNFC's player ambassadors will amplify public service announcements, social media content, and local community education events to raise awareness about cardiovascular disease and CPR education in women. The league has also implemented a requirement for all coaches to be certified in CPR, AED, and first aid.
Researchers have discovered new interactions and identified potential targets for cancer therapy by analyzing the effects of inactivating DNA repair genes. By comprehensively studying the interactions between more than 500 crucial genes, the team gained important new insights into how cells maintain genome integrity.
Researchers have validated a blood test for early detection of Alzheimer's disease, achieving over 90% accuracy in hospital patients. The test uses a biomarker called phospho-tau217 and has the potential to reduce costs associated with current diagnostic tests, improving access to care and treatment.
Jiawei Yang creates bioadhesives with two layers, a transparent solid hydrogel layer and a clear liquid adhesive layer, to provide fast, strong, stable, and deep adhesion in the body. The new bioadhesives have potential applications in treating Parkinson's disease, heart failure, and healing damaged cartilage.
Researchers from Yale University found that participation in faith-based or community-based extracurricular activities can increase U.S. adolescents' awareness of the dangers of binge drinking. The study suggests that these types of activities could play a crucial role in preventing excessive alcohol consumption among young people.
A recent study from Michigan State University found that brown rice contains higher levels of arsenic than white rice, posing a potential health risk for infants and children under age 5. The researchers also highlighted the importance of considering food safety along with nutrition when making food choices.
Researchers at KAIST discovered that DDX54 is the master regulator hindering immunotherapy's effectiveness in lung cancer. Supressing DDX54 enhances immune cell infiltration into tumors and improves immunotherapy efficacy.
Researchers from Boston University Chobanian & Avedisian School of Medicine have found a new role for the transcription factor Traffic Jam in promoting female fruit fly fertility. The discovery solves the 30-year-old mystery of how Flamenco gets activated to protect fruit fly ovaries from genetic parasites.
Researchers observed and identified the water-induced degradation mechanism of perovskite at the atomic scale, proposing strategies to enhance its stability. Coating nanocrystal surfaces with ligands or hydrophobic polymers slows down degradation rates, providing critical insights into the fundamental stability issues of perovskite.
A novel AI framework, MULGONET, improves cancer recurrence prediction by integrating genomic, epigenetic and transcriptomic data. The model overcomes limitations of traditional machine learning models by automatically linking genes to biological processes, enabling trans-cancer applicability.
Researchers have developed a cleaner method to extract iron from synthetic iron ore using electrochemistry, which could reduce air pollution emissions and energy consumption. The new process is estimated to be comparable in cost to traditional blast furnaces.
Thoracic surgeons can rely on DeepSeek's accurate diagnoses, precise surgical planning, and early warning systems to enhance patient care. However, challenges persist, such as limited dataset availability and high economic burdens, which must be addressed for seamless integration of AI in thoracic surgery.
Scientists at Rice University have discovered how a disappearing electronic pattern in a quantum material can be revived under specific thermal conditions. The finding opens new doors for customizable quantum materials and in-situ engineering, where devices are manufactured or manipulated directly at their point of use.
STITCHR uses an RNA system to replace entire genes, overcoming CRISPR limitations in targeting every mutation. The tool offers a one-and-done approach for gene therapy, addressing cystic fibrosis and other diseases with thousands of mutations.
Researchers have developed a new method to identify and classify pancreatic cancer cell subtypes by analyzing sugar molecules on the surface of cells. This approach may lead to more precise diagnoses and better treatment options for patients.
Researchers have identified nearly 300 genetic disorders that can be treated during pregnancy or in the first week of life, offering unprecedented opportunities for early intervention. The 'treatable fetal findings list' aims to improve diagnosis and enhance treatment options for fetuses with these conditions.
A national survey reveals significantly higher rates of five mental health conditions in incarcerated individuals and those with recent criminal-legal involvement compared to community members. The study emphasizes the critical need for informed care and treatment to address the high rates of incarceration and improve community support.
This study reveals NAT10 is crucial for spermatogonial proliferation and differentiation. In Nat10-deficient mice, infertility occurs with reduced testicular sizes, germ cell depletion, and a loss of spermatogonial homeostasis.
A new configuration approach for radial distribution systems incorporates distributed renewable energy resources, achieving superior voltage stability, reduced system losses, and improved resilience. The study also quantifies significant environmental benefits, including reduced CO2 emissions and optimized resource utilization.
A new analysis finds a significant increase in people dying at home due to ischemic stroke, reversing a 10-year decline, with rural communities and Black Americans more likely to die in less specialized care environments. The study also reveals rising death rates from stroke, despite improvements in access to palliative care.
A Southwest Research Institute-led team identified a rare helium isotope (³He) emitted from the Sun, with a concentration 200,000 times higher than usual. The unusual occurrence supports earlier theories suggesting weak magnetic field strength and minimal turbulence in the plasma.
Computer simulations show that captured CO2 can be permanently stored underground by mixing with groundwater, creating a denser liquid that sinks and remains there. Suitable geological conditions, such as impermeable rock layers and porous aquifers, are necessary for effective CO2 storage.
A new report reveals that Indonesia's small farmers can increase productivity and market access through technology-driven innovations. The report outlines ten best practices for agritech startups and wider ecosystems to enable and shape the country's rural startup ecosystem.
Researchers created a hopping robot that can traverse challenging terrains, carry heavy payloads, and uses less energy than aerial robots. The robot's springy leg and flapping-wing modules enable it to jump over obstacles and adjust its orientation mid-air.
A comprehensive longitudinal analysis of obesity trajectories identified distinct patterns affecting brain morphology, function, and cognition in middle-aged and older adults. The study suggests sustained obesity accelerates brain aging, highlighting the clinical importance of long-term monitoring and management.
Researchers have identified a potential precision medicine approach to prevent chronic kidney disease progression by targeting type 5 collagen, a minor component of scar tissue. A repurposed anti-cancer drug, Cilengitide, has been shown to slow kidney scarring and disease progression in high-risk individuals.
A survey conducted among ESTS members revealed that sympathetic surgery is commonly used for hyperhidrosis and facial flushing, with a preference for nerve cutting over clipping. However, there was significant heterogeneity in practice, highlighting the need for standardization and further research.
Researchers optimize starting materials for electrochemical iron production, identifying cost-effective iron oxides. The process could reduce carbon emissions and make the steel industry more sustainable.
The study found that patients with coaxial silicone drains had lower analgesic consumption and better-preserved respiratory muscle strength during the first 2 postoperative days. This suggests that coaxial SIL drains can reduce postoperative pain and improve patient comfort and recovery following VATS lobectomy.
A new study from Boston University School of Medicine found that X-rays can predict common low back pain problems in approximately 75% of cases. In these instances, X-rays may be a preferred initial imaging study, reducing the need for MRI scans and associated costs.
A new THz metasurface device can continuously manipulate polarization states on different output planes over a relatively long propagation distance. It achieves this by decomposing incident polarized THz waves into two orthogonal circularly polarized components, which then recombine to produce linearly polarized waves.
Researchers introduce an innovative approach using dynamic topic modeling to analyze annual and quarterly reports, uncovering hidden risk factors. The novel method creates tradable indices with a cost-effective alternative to traditional index construction.
A recent study found that ischemic stroke mortality rates have increased in the US over the past two decades, particularly among racial minorities and rural residents. The majority of these deaths now occur at home, rather than in hospitals or medical facilities.
Researchers precisely manipulate single-atom and -electron tailored gold nanoclusters to probe magnetic spin's influence on catalytic activity. They find that spin density shifts outward as the central atom is removed and concentrate on iodine atoms.
A study in the journal Cell Host & Microbe found that a diet rich in soluble fiber can protect against pathogenic bacteria like Clostridioides difficile. Consuming soluble fiber produces compounds like acetate, which regulates immune response and reduces inflammation.
Novel biomarkers like miRNA-34a link anthracyclines to cardiotoxicity, while stem cell therapy and nanotechnology offer potential for prevention and treatment. Traditional strategies have limitations, but new approaches hold hope for improved patient outcomes.
A USF-led study found that when some members in a cohort engage in job-seeking behaviors, newcomers are more likely to do the same and ultimately leave the organization. The effect is mitigated if the newcomer has a strong preference for the organization's geographic location.
A recent study analyzed user reviews of popular apps and found that when developers imitate competing apps' features, customers are often right. However, when it comes to innovative features, developers should follow their own instincts unless they can fully understand user suggestions. The researchers used AI to sift through 7 million...
Researchers have discovered two distinct pathways of bone regeneration driven by early progenitor cell activation in male and female-derived organoids. The study highlights the importance of a shared set of secreted proteins in the healing process, with potential applications for personalized medicine and noninvasive biomarkers.
Researchers at Cornell University have developed a cost-effective way to track atmospheric mercury using wild fig tree rings in the Peruvian Amazon. This method offers a potential solution for understanding mercury spread and impact on ecosystems.
Researchers found evidence of hunter-gatherers accessing remote islands like Malta thousands of years earlier than previously thought. They discovered stone tools, hearths, and cooked food waste at the Latnija cave site, indicating that these ancient seafarers were capable of sustained journeys across open water.
Eight hospitals, including Oklahoma Children’s Hospital, receive funding to refine discharge processes for mothers and babies with neonatal abstinence syndrome. The program aims to provide continuity of care through prenatally-based education and post-discharge support.
A new database of 400 years of sightings compiled by researchers at Colorado State University may help anticipate when and where milky seas will occur. The archive includes eyewitness reports, satellite data, and individual accounts submitted to the Marine Observer Journal.
Researchers have developed a new understanding of electrolyte wetting in advanced lithium-ion batteries, addressing a critical bottleneck in manufacturing. The study's findings reveal that manufacturing processes impact wetting behavior through key parameters like permeability and capillary forces.
Jason Cong recognized for contributions to field-programmable system design and customizable computing, enabling efficient FPGA programming from software languages like C/C++.
Pregnancy-related deaths in the US rose during 2018-2022, with significant disparities by state and ethnicity, underscoring the need for urgent public health action.
A novel artificial solid electrolyte interface based on non-coordinating charge transfer significantly improves the stability of aqueous zinc metal batteries. This design enhances cycle life, reduces side reactions, and promotes uniform zinc deposition, leading to improved battery performance.
Analysis of citizen science data suggests that warmer ocean temperatures can increase loggerhead sea turtle nesting sites along Italy's coastlines. Preserving natural beaches is crucial for maintaining these habitats.
Researchers discover that oxygen-starved cancer cells use the same gene as high-altitude populations, such as Tibetans and Sherpas, to adapt to hypoxia. This convergence in genetic adaptation could lead to new therapeutic targets for cancer treatment.
A recent study by Michigan State University found that the percentage of nonparents who never want children has doubled over the past 20 years, rising from 14% in 2002 to 29% in 2023. This trend is part of a growing group of childfree adults whose needs are often overlooked.
The study provides a comprehensive reference for six ape species, including siamang, Sumatran orangutan, gorilla, bonobo, and chimpanzee. The ape genomes offer new insights into human and ape evolution, genetic differences among species, and potential therapeutic applications.
A new study from the University of Gothenburg found that titanium micro-particles are consistently present at all examined implants, even those without signs of inflammation. The researchers identified 14 genes that may be affected by these particles, but further research is needed to understand their impact on tissue health.
Scientists have created a detailed map of U2OS cells, revealing previously unknown protein functions and assemblies. The study will help researchers understand how mutated proteins contribute to childhood cancers and provide a blueprint for mapping other cell types.
A new study by researchers at Tufts University suggests that a lack of vitamin K may increase inflammation and hamper proliferation of neural cells in the hippocampus, a key region for learning and memory. Vitamin K deficiency was also associated with increased neuroinflammation and reduced neurogenesis, leading to noticeable cognitive...
Researchers at the University of Gothenburg have discovered a molecule that helps more mitochondria function properly, improving energy production in cells from patients with POLG mutations. This breakthrough paves the way for a new treatment strategy and may have broader therapeutic use for other mitochondrial diseases.
The inaugural eLTER Science Conference in Tampere, Finland will explore integrated approaches to ecosystem research. The conference features sessions on groundwater dynamics, novel environmental monitoring technologies and ecosystem restoration.
Researchers studying ancient rhino teeth found at Nebraska's Ashfall Fossil Beds State Historical Park discovered that prehistoric rhinos lived in large herds. The animals' limited mobility suggests they didn't respond to the volcanic eruption or migrate seasonally, instead likely dying from prolonged exposure to ash and lack of food.
A new method captures totipotency using a short-term high-dose treatment of Pladienolide B, reprogramming classical mouse embryonic stem cells into transient totipotent blastomere-like stem cells. These cells exhibit remarkable developmental potential and self-organize into blastoid structures mimicking early embryonic development.
A new NIH study found that children born in lower-opportunity neighborhoods are more likely to experience repeated asthma flares requiring emergency care. Non-Hispanic Black children have the highest incidence rates of severe childhood asthma, also known as asthma with recurrent exacerbations (ARE).
Researchers found explosive growth rates of cancerous cells years before diagnosis, with variation in growth rates between patients. The study suggests that a single genetic variation drives the disease, making it an outlier compared to other cancers.
Researchers developed a dual-action nanotherapy that converts white fat into beige fat and reduces obesity-related inflammation, significantly improving metabolic health without detectable toxicity.
Research reveals pregnancy-induced immune shifts affecting disease susceptibility and delivery outcomes, with adaptations in T cells, B cells, and monocytes identified across stages.
A rare case of Exophiala jeanselmei pneumonia was reported in an immunocompetent patient with interstitial lung disease. The patient presented with malaise, cough productive of black sputum, and bilateral lung field crackles.
SeamFit's innovative use of flexible conductive threads and machine-learning algorithms accurately detects movements and counts reps during various exercises. This wearable technology promotes practicality in exercise tracking, potentially enhancing human-AI interaction by monitoring daily activities.
Patients with acute type-A aortic dissection (ATAAD) show higher preoperative white blood cell count, IL6, IL8, TNFα, DAO, iFABP, and PGN levels, but lower PaO2/FiO2 ratio compared to controls. Postoperative levels of these markers increase, leading to worsened hypoxemia.
Researchers successfully assembled a miniaturized human nervous system to reconstitute the ascending sensory pathway, which transmits sensations from the skin to the brain. The new construct promises to accelerate understanding and treatment of chronic pain by allowing for non-invasive modeling and manipulation of the pain pathway.
Researchers utilized machine learning models to identify key surface attributes modulating immune response, paving the way for improved implant materials. The study revealed pivotal factors regulating cytokine secretion and offered insights into designing alloys with optimized immunoregulatory functions.
A literature review found that weak coughs increase the risk of extubation failure and prolonged hospitalization. Employing individualized cough exercises, such as increasing inhaled volume and utilizing oscillation techniques, can significantly improve patient outcomes.
The Korea Institute of Energy Research (KIER) has developed ultra-lightweight flexible perovskite/CIGS tandem solar cells achieving a power conversion efficiency of 23.64%, the highest recorded efficiency among flexible perovskite/CIGS tandem solar cells.
A comprehensive review article highlights emerging strategies that enable environmentally benign coupling reactions, reducing reliance on rare metals and lowering energy consumption. The hypervalent iodine approach facilitates selective bond formation with high functional group tolerance and broad substrate scope.
A University of Ottawa-led team examines the punishing costs of TB care, finding that patients face 'catastrophic' expenses despite free treatment being available in many countries. The review identifies areas for intervention to reduce patient costs and improve sustainable TB mitigation strategies.
Researchers have found that people with cannabis use disorder have elevated dopamine levels in a brain region associated with psychosis. This could explain why frequent cannabis use increases the risk of hallucinations and delusions. The study's findings may help doctors educate patients about the potential risks of frequent cannabis u...
A study by the University of Barcelona reveals that dynamic BH3 profiling can predict the effectiveness of ALK inhibitors in treating non-small cell lung cancer. The technique helps select the best drug for each patient, overcoming tumour adaptations to inhibitors.
A new study from the University of Georgia found that millennials have lower levels of financial well-being and knowledge, while boomers have the highest. Financial skills and behavior also tend to improve with age. Insights from this study could help develop programs to improve financial well-being across generations.
Chinese scientists have discovered that the Moon's farside mantle contains less water than the nearside, according to analysis of basalts collected by the Chang'e-6 mission. The research team found a significant disparity in water content between the two hemispheres, mirroring lunar surface asymmetries.
Researchers have developed a high-pressure liquid seal technique to eliminate bubble formation in PCR chips, improving the reliability of PDMS-based chips for critical applications. The innovation simplifies chip design, boosts efficiency and reduces errors, making it more accessible for medical diagnostics.
A retrospective study of 20 cases of pulmonary MALT lymphoma found characteristic HRCT features such as air bronchogram and bronchiectasis, predominantly in the left upper lobe. Pathologically, tumors exhibited monocytoid and centrocyte-like cells with minimal atypia and B-cell markers CD20 and CD3.
Keck Medicine of USC will open a four-story medical office building in Pasadena in fall 2025, featuring state-of-the-art technology and access to acclaimed specialists. The location will offer a range of services including autoimmune diseases care, cardiovascular care, comprehensive oncology, and orthopedics.
Researchers have discovered a significant increase in inflammation and C-reactive protein levels in female patients with sickle cell disease during the follicular phase of their menstrual cycle. This finding may help identify potential targets for managing pain crises, particularly when combined with hormonal contraceptives.
Researchers found individuals with cannabis use disorder exhibit increased dopamine levels in the brain, a key factor in psychosis. This study suggests that regular cannabis use is linked to signs of increased dopamine activity.
A Cornell University-led collaboration has developed a low-cost method to produce carbon-free 'green' hydrogen via solar-powered electrolysis of seawater. The process produces 200 milliliters of hydrogen per hour with 12.6% energy efficiency directly from seawater under natural sunlight.
Researchers have developed a new approach to overcome treatment resistance in estrogen receptor-positive (ER+) breast cancer. Dual aromatase-steroid sulfatase inhibitors (DASIs) show promise in effectively blocking both enzymes involved in oestrogen production, potentially reducing tumour growth.
The new robotic gripper, called GRIP-tape, uses a combination of softness and stiffness to grasp fragile fruits and vegetables with precision. With its ability to navigate obstacles and deposit objects into containers, the gripper has shown promising results in lifting large fruits like lemons.
Rebecca Conant, MD, a pioneering leader in home-based geriatric care, has been honored by the American Geriatrics Society (AGS) as Clinician of the Year for her transformative impact on geriatric medicine. Her leadership and innovations have expanded access to high-quality, person-centered care for older adults.
A new review suggests a strong association between gum disease and chronic liver conditions, including cirrhosis and metabolic dysfunction. The 'oral-gut-liver axis' theory proposes that pathogenic bacteria from the mouth can exacerbate liver inflammation and fibrosis through dysbiosis and increased gut permeability.
A new study found that more 'optimistic' medical detection dogs performed better overall on detection tasks, while 'pessimistic' dogs had higher scent detection specificity. The researchers suggest that judgment bias testing could be a screening tool for potential detection dogs.
Researchers developed a method to detect epileptic seizures in humans using canine EEG data. The approach leverages feature similarities across species and modalities, reducing input space discrepancies. Euclidean alignment and knowledge distillation are key components of the proposed joint alignment mechanism.
A study found that New York's opioid restriction law led to decreased opioid quantities after total joint replacement surgeries. The findings suggest refining laws may further reduce opioid prescribing nationwide.
The PV Doctor uses AI-driven analytics to monitor and optimize solar PV system performance. It detects root causes of underperformance and provides actionable solutions to prevent energy losses and protect long-term asset value.
Researchers developed a first-of-its-kind wearable device that tracks gas emissions from the skin to monitor health, detect wounds and infections, and track hydration levels. The device offers a new way to assess skin health without contacting delicate tissues.
A comprehensive study examined vehicle-mounted wireless power transfer systems to ensure user safety during electric vehicle charging. The research revealed key considerations for designers: optimizing field distribution patterns, mitigating misalignment effects, and shielding high-frequency cables.
Researchers found that nanoplastics in soil exhibit varying behavior depending on soil type and pH levels, affecting their aggregation and adsorption onto soil particles. Understanding these interactions is crucial for developing effective strategies to mitigate plastic pollution.
Researchers found significant disparities in quality of care and outcomes for patients with metastatic pancreatic cancer. Patients with higher social vulnerability indices were less likely to receive guideline-concordant systemic therapy, palliative care, or survive over 12 months.
The largest genome-wide association study on osteoarthritis identifies over 900 genetic associations, including 700 genes involved in the disease. These findings offer new insights into the genetic landscape of osteoarthritis and potential drug repurposing opportunities.
The DGIST research team successfully fine-tuned the Rabi oscillation of polaritons by leveraging changes in electrical properties induced by crystal structure transformation. This allows for precise control over quantum particle states, enhancing the feasibility of practical quantum technology.
A new study reveals that the Saharo-Arabian Desert experienced recurrent humid intervals over the past eight million years, supporting migrations of water-dependent animals, including early ancestors. These wetter periods likely sustained monsoonal precipitation from the South, which gradually weakened over millions of years.
A recent study found that urban bird species exhibit more elaborate colours and less brown plumage compared to those that fail to thrive in cities. This suggests that urbanization plays a role in shaping the colouration of birds in these environments.
The study reveals new insights into the 'language' of gene expression, identifying key motifs that influence human development and disease risk. By analyzing 58,000 pairs of transcription factors, researchers estimated they identified between 18 and 47% of all human transcription factor pair motifs.
The article explores how DeepSeek's advanced language model can enhance ARDS management by detecting signatures earlier and with greater precision, identifying distinct phenotypes, and providing personalized treatment strategies. This could lead to improved patient outcomes and reduced mortality rates.
Physician burnout rates have dropped slightly since the last study in 2021, but still remain a concern, affecting quality of patient care and work-life integration. Women physicians are more likely to experience burnout than men, while doctors in certain specialties like emergency medicine face heightened risk.
Engineered materials mimic quantum behaviors, allowing for the simulation of Schrödinger dynamics in classical systems. This breakthrough enables the study of quantum phenomena in more accessible environments, paving the way for novel technologies.
A new study reveals that hunter-gatherers crossed over 100 km of open water to reach Malta 8,500 yrs ago, 1,000 yrs before the arrival of farmers. The researchers found evidence of stone tools, hearths, cooked food waste, and wild animal remains.
ENVLPE addresses limitations of previous gene editing delivery systems by hijacking intracellular transport mechanisms to ensure efficient packaging and protection of gene editors. The system was tested in a mouse model of inherited blindness, achieving astounding restoration of vision, and has potential for cancer therapy advancements
A large-scale program in Turkey reduced disciplinary problems and improved academic achievement among disadvantaged middle school students. The program's success was attributed to buy-in from challenging adolescents who crave status and social recognition.
A new study reveals that the US national vaccine strategy saved more money than it spent on testing, buying and delivering COVID-19 vaccines after just one year. The analysis found that the vaccines reduced serious illness and deaths, resulting in significant cost savings.
Researchers found evidence of recurring humid phases in the region over the past 8 million years, allowing for animal and hominin migrations. These wet conditions supported diverse species such as crocodiles and hippopotamids, facilitating biogeographic exchanges between Africa and Eurasia.
A study found that smaller embryos already hatching are more likely to be chromosomally normal. This insight helps fertility clinics select better embryos during IVF, particularly for women over 35 or those undergoing PGT-A.
A new method uses pulsed infrared light to analyze molecular patterns in blood plasma, potentially identifying cancer-specific 'fingerprints'. The technique showed accuracy of up to 81% in detecting lung cancer and differentiating it from control samples.
The study introduces an innovative method to detect and classify floodplains based on their ability to attenuate floods. The Hydraulic Floodplain Classification emphasizes the variable capacity of the landscape to influence flood routing, enabling better water resource assessments and floodplain management applications.
A global team of neuroscientists has created the most detailed wiring diagram of a mammalian brain, revealing new cell types, characteristics, and organizational principles. The MICrONS Project's findings have transformative potential for neuroscience and medicine, offering a blueprint for understanding intelligence and disorders like ...
Researchers found that hot car exhaust can improve the efficiency of catalysts by forming nano-sized clusters on their surface, increasing reaction sites and oxygen activation. This serendipitous discovery could lead to more efficient catalysts with significant cost savings.
A new study by UC Davis School of Medicine identifies four major areas of need among wildfire victims, including mental health support and health information. The research reveals that mental health needs are the most predominant health-related need at all time points.
Researchers at ISTA have discovered a new DNA marker, N4-methylcytosine (4mC), crucial for sperm function and fertility in the liverwort Marchantia polymorpha. The team found that high levels of 4mC are necessary for agile sperm development, affecting swimming speed, direction, and fertilization success.
An international team of agronomists calls for a new approach to estimate crop yield potential and gaps. Current statistical models rely on best-case scenarios and extrapolate a single yield potential across large regions, leading to conflicting results.
A new study describes a case where long-read genomic sequencing (LRS) was used to diagnose RFX3 haplo-insufficiency syndrome in a patient with autism spectrum disorder and intellectual disability. The study highlights the potential benefits of genetic testing in psychiatric care, including expediting workups for inpatient patients.
A study by University of Illinois researchers uses wearable technology to track heart-rate recovery after exercise and predict cardiovascular risk. The team developed a tool for analyzing data to identify participants at higher or lower risk, finding consistent results despite small sample size.
Researchers investigated the neuroregenerative potential of 5-NOT and Epi, discovering they protected SH-SY5Y cells from MPP+ toxicity by regulating key proteins. The findings support 5-NOT as a glycomimetic drug candidate for Parkinson's disease treatment.
Researchers developed a technology that dramatically enhances the stability of ultra-thin metal anodes using electrolyte additives, improving both lifetime and efficiency of lithium batteries. This advancement enables longer-lasting batteries for various applications, including electric vehicles and unmanned aerial vehicles.
A new book examines the complexities of British-Irish relationships, exploring novel concepts to navigate national identities, cohesion, and fragmentation. The research aims to strengthen existing partnerships and build new ones as the two islands' political futures become increasingly entangled.
Researchers at Ohio State University Wexner Medical Center have discovered a new way that neurons act in neurodegeneration by studying human neural organoids from patients with frontotemporal lobar degeneration (FTLD). They found GRAMD1B plays a significant role in managing cholesterol and lipid stores, which are linked to brain diseas...
Research suggests climate change is contributing to the increase in allergic rhinitis, also known as hay fever. Global warming has been linked to longer pollen seasons and higher pollen concentrations, leading to increased symptoms and healthcare usage.
New research reveals changes in brain connectivity during chemotherapy in breast cancer patients, particularly in the frontal-limbic system and cerebellar cortex. These changes worsen as treatment continues, suggesting that chemotherapy can quickly disrupt brain function in breast cancer patients.
Researchers found that lottery-winning pre-K students entered kindergarten more prepared in math and reading, but gains faded by grade 4. Disadvantaged students benefited the most from attendance.
The UN University's new report emphasizes the need for deep systemic changes to address climate change, biodiversity loss, and pollution. It introduces the Theory of Deep Change, which identifies structures and assumptions that perpetuate these challenges, and highlights five areas where urgent transformation is needed.
Researchers developed an injectable hydrogel containing fish swim bladder components to repair damaged heart tissue, showing enhanced cardiac cell adhesion and stretching. The treatment also promoted new blood vessel formation and reduced inflammation in a rat model of ischemic heart failure.
A new study from the University of Sydney found that poor oral health is significantly associated with higher instances of migraines and abdominal/pain in women. The research identified specific oral microbes correlated with certain pain conditions, including fibromyalgia.
A Stanford study finds that a pivot to clean energy technologies by 2060 would improve energy security and reduce trade risks for most nations. The study analyzed potential new vulnerabilities under decarbonization relative to those associated with continued reliance on fossil fuels.
Risky driving by parents and motorists during school drop-offs is a widespread issue, with 98% of elementary schools witnessing unsafe behavior. Experts suggest improvements to the built environment around schools to address this serious concern.
A study published in Heart Rhythm has found that handheld electro-shockers can interact with cardiac implantable electronic devices (CIEDs) such as pacemakers, posing a risk to individuals. The risk is primarily based on the applied voltage, but also on the manufacturer and type of implanted CIED.
The RAND survey found that over 80% of public school pre-K teachers use multiple curriculum materials, with some combining materials for specific domains and others creating their own. However, many report insufficient time for instructional planning and professional learning.
A study published in Water Biology and Security reveals that warm temperatures induce sex reversal in ricefield eels by expressing male sex determination genes in ovarian tissues. This process depends on Trpv4, a cation channel protein that controls calcium flux into cells.
A recent study has revealed the interaction mechanism between mitochondrial proteins HAX1 and CLPB, filling a research gap in structural dynamics and functional association. The high-affinity binding properties between the two proteins have been determined using nuclear magnetic resonance technology, providing new research perspectives...
Researchers have successfully displayed three-dimensional graphics in mid-air that can be manipulated with hands. The innovation allows for direct interaction with holograms, enabling users to grasp and rotate virtual objects naturally.