A calcite deposit in a southern Nevada cave has provided new insight into the region's hydroclimate, revealing significant shifts in temperature and rainfall over the last 580,000 years. The analysis suggests that temperature, availability of water, and vegetation are tightly coupled, with changes in one area impacting others.
A new research letter highlights major gaps in how opioid use is tracked among older adults receiving post-acute care under Medicare. Current data sources may overlook most opioid use during critical transition periods, leading to inaccurate understanding of medication use and policy decisions.
A new study finds that even Australia's most protected marine areas will likely suffer extreme climate shocks by 2040, threatening thousands of marine species. The effects will be widespread, with 'safe havens' disappearing as ocean conditions considered extreme today become the new normal.
Agricultural producers can now use RGB images from smartphones to analyze crop attributes such as nutrient content and chemical composition. The researchers developed a dataset of reconstructed multispectral images for sweet potatoes, which can be used by anyone for modeling purposes.
The Center for Open Science has been awarded a grant from the Robert Wood Johnson Foundation to develop a community-driven strategic plan for preserving federally-funded scientific data. The project aims to complement existing initiatives by developing a framework for long-term stewardship of at-risk datasets and repositories.
A new study aimed to standardize POCUS education, leading to more physician trainees learning the technique. The research found consensus on over 50 essential skills and teaching methods, promoting better patient care with faster diagnosis times.
Researchers found that question-and-answer messaging significantly increased curiosity, topic-specific information seeking, and in some cases promoted healthier behaviors. In controlled experiments with over 49,000 participants, Q&A messages led to increased self-reported adherence to protective health behaviors.
A landmark trial has shown that a structured approach to infection prevention and treatment can save women's lives. The programme reduced severe maternal infections and deaths by about one-third (32%) compared to usual care.
The University of Texas MD Anderson Cancer Center has been awarded $29 million by the Cancer Prevention and Research Institute of Texas (CPRIT) to support impactful prevention programs and groundbreaking cancer research. The funding will also enable the recruitment of a CPRIT Scholar.
Researchers at Children's Hospital of Philadelphia have identified four genes linked to osteoblasts and their ability to mature, which can affect bone mineral density. A polygenic risk score called genetic quantitative ultrasound speed of sound (gSOS) was also found to be associated with higher bone mineral density and reduced odds of ...
A new longitudinal study found that young people who engage in gaming habits with gambling-like elements are more likely to gamble with real money. The research team urges policymakers to broaden regulations beyond loot boxes and includes social casino games, prize wheels, and gambling videos in the scope.
A new analytical tool can improve a hospital's ability to limit the spread of antibiotic-resistant infections by inferring asymptomatic carriers. The method, developed by Columbia University researchers, combines multiple data sources to predict the spread of an infection in the hospital setting.
A new three-year neurorehabilitation program will be implemented to improve the brain health of pediatric cancer patients with brain tumors from diagnosis through long-term survivorship. The program aims to strengthen brain structure and function, addressing cognitive changes often an invisible disability for these patients.
A team at the University of Pennsylvania has solved the mechanism of action of hydralazine, revealing its potential to halt the growth of brain cancer cells. By blocking an oxygen-sensing enzyme, hydralazine can reduce intracellular calcium levels, causing blood vessels to relax and tumor cells to enter a dormant state.
A new study suggests that coyotes are more likely to overlap with humans in areas with high levels of open space, such as parks and golf courses. The analysis found that coyotes were attracted to areas with moderate levels of open space, like parks or golf courses, where they could find food and shelter. In contrast, coyotes may be les...
Researchers found that a small section of intact corpus callosum is enough to sustain full integration of the two brain halves, contrary to previous assumptions. The discovery has implications for epilepsy surgery and brain injury recovery.
The University of Cincinnati has received a $985,000 grant to test Healthy Eating for My Infant (HEMI), a community-based intervention promoting healthy eating and feeding practices for children 0-12 months. HEMI aims to address specific risk factors and barriers faced by low-income families. The NIH-funded study will enroll 60 infants...
Eight countries support the Resilient Agriculture Investment for net-Zero land degradation (RAIZ) accelerator, which offers a 'quadruple-win' for climate, biodiversity, food security, and desertification. RAIZ aims to mobilize $105 billion in private investment to restore degraded agricultural land at scale.
Researchers identified and characterized the RibD-enolase complex in Francisella novicida, revealing key interactions and catalytic activities. The study provides the first structural and biochemical characterization of the complex, establishing a foundation for further investigations into its functional significance.
A nationwide survey by the American Gastroenterological Association found that nearly two-thirds of Americans recognize obesity as a chronic disease, while over 80% believe insurance should cover its treatment. However, barriers such as high out-of-pocket costs and lack of coverage for procedures or medications hinder access to weight-...
A new study shows a significant increase in the use of computed tomography (CT) scans of the head in emergency departments across the US from 2007 to 2022. The study found that Black people were 10% less likely to receive a head CT scan than white people, and those on Medicaid insurance were 18% less likely.
The European Alliance of Associations for Rheumatology has developed a new disease activity score (EAPSDAS) to assess clinical manifestations in antiphospholipid syndrome (APS). The score evaluates thrombotic, obstetric, microvascular, and non-thrombotic symptoms, providing insights into disease activity and treatment response.
Two new studies from Schneider Electric and Boston University Institute for Global Sustainability identify 95 sociotechnical barriers and 50 risks hindering progress in the high-stakes buildings sector. The research highlights complex interplay between economic, political, social, and behavioral factors driving inefficiencies and costs.
A team of researchers, led by Lijing Wang, used field data and modeling to explore the factors influencing mountain headwater streams. They found that evergreen forests act as a buffer for excessive snowmelt flow, while subsurface conditions like permeability control streamflow dynamics.
A UT Austin study found that switching from whole-food beef to a plant-based meat substitute altered the types of fats in breast milk within six days. The study tested nutritionally balanced meals with identical macronutrients except for the protein source.
Researchers have developed a transgene-free approach to construct mouse post-implantation embryo models, utilizing extended pluripotent stem cells. These models recapitulate key features of post-implantation development, including gastrulation and extraembryonic tissue formation.
A new type of DNA damage, glutathionylated DNA adducts, accumulates at high levels in mitochondrial DNA, affecting energy production and stress response. The discovery sheds light on how cells sense and respond to stress, with potential implications for diseases like cancer and diabetes.
Researchers at Columbia University Irving Medical Center have successfully used focused ultrasound to open the blood-brain barrier in three children with diffuse midline glioma, a rare and aggressive brain cancer. The technique allowed chemotherapy drugs to reach tumors, leading to some improvement in patient mobility.
A study on printing press regulation in early modern England reveals the importance of diverse voices and financial resources in shaping regulation. The research highlights how societies regulate new technologies, including AI, by involving a broad range of stakeholders to prevent monopolization and ensure transparency.
A team of researchers has identified a powerful selenium-reducing bacterium that can convert inorganic selenium into nanoparticles, promoting plant growth and enhancing the flavor compounds in tea leaves. The optimized bio-nano selenium agent enriched tea leaves with organic selenium, lowered levels of bitter catechins and harmful elem...
Researchers uncover how light and humidity affect emerald green paint, leading to degradation and brittleness. They propose strategies for preserving and monitoring masterpieces containing this pigment.
Researchers are studying the Great Oxygenation Event (GOE) using deep drilling in Gabon, Africa, to understand the timing and pace of oxygen accumulation. The project aims to provide clues about the changing amount of oxygen in the environment at the time.
Recent studies by Brazilian scientists clarify key roles of STIP1 and Maspin in vital cellular processes, including embryonic development, cell communication, and tissue renewal. These findings contribute to cancer research, regenerative medicine, and understanding cellular homeostasis.
Researchers at Northwestern University developed the first haptic device achieving human resolution, recreating digital touch with clarity and detail. The VoxeLite device wraps around a fingertip to give users a realistic feel for digital environments, including virtual reality systems and assistive technologies.
A comprehensive single-cell atlas of endocrine aging was established, revealing both shared and organ-specific aging mechanisms. The study suggests that immune-endocrine interactions are a key node for potential interventions, and future studies may uncover the role of aged endocrine organs in systemic aging.
Researchers discovered that NDRG3 slows down cellular transport to conserve energy during low-oxygen conditions. The protein acts as a sensor for lactate, which accumulates in cells when oxygen is limited.
Researchers aim to prove Einstein wrong by testing Lorentz invariance, a fundamental concept in quantum field theory and the Standard Model of Particle Physics. Despite not succeeding, their new bounds improve upon previous limits by an order of magnitude.
A recent study found distinct changes in NAD-related metabolites in women with recurrent miscarriage, suggesting a deeper metabolic imbalance. The findings may lead to the identification of potential biomarkers for risk assessment and new avenues for treatment.
A new study found that remote work can improve quality of life by providing choice and autonomy, but poor support can lead to feelings of isolation and decreased job satisfaction. The research highlights the importance of access to amenities like green spaces and local services for sustainable remote work.
The partnership aims to strengthen Catholic theology's engagement with neighboring disciplines and provide high-quality education for various professional fields. The joint research projects will also be intensified, and a cooperation council will address fundamental questions related to the inter-institutional faculty.
A new study reveals how the GRP94 protein shields itself during formation and suggests a way to target it for future disease treatments. The research uses cryogenic electron microscopy to capture images of the protein's interactions with other molecules, shedding light on its role in glycosylation.
Researchers found over 800 vertebrate fossils from a small area, including dinosaurs and other prehistoric creatures. The discovery provides valuable insights into the evolution of European dinosaur faunas during the Late Cretaceous period.
A study investigated the effect of pasteurized versus non-pasteurized milk on dairy calf gut health. Non-pasteurized milk promoted a more stable microbial community and higher abundance of beneficial Lactobacillus species.
A study by the University of Portsmouth reveals that microplastics are present in 100% of donkey faecal samples, posing a serious risk to animal health and potentially contaminating food supplies. The research emphasizes the need for coordinated global and local action to address the plastic crisis.
Scientists use XL-Calibur telescope to measure polarization of light around Cygnus X-1 black hole, gaining insights into matter's fall and energy release. The observations will be used to test computer simulations and shed light on black hole physics.
A team of researchers from UNICAMP in Brazil developed a method to extract bioactive compounds, including caffeine and phenolic compounds, from cocoa bean shells using native bee honey as an edible solvent. The resulting product has a strong chocolate flavor and potential nutritional benefits.
A practical framework for a Medical Data Element Ecosystem (MDEE) is proposed to address challenges in medical data sharing and use. The MDEE covers micro-level stakeholder roles and macro-level technological innovation, institutional reforms, and ethical governance.
Researchers developed a persistent luminescence nanoprobe to detect H₂O₂ in real samples, overcoming background fluorescence interference. The probe's high selectivity and reproducibility make it suitable for food safety monitoring, environmental inspection, and biomedical assays.
Linda Bulone, a Queens Cancer Center Oncology nurse, received the 2025 Alliance Clinical Research Professionals Research Integrity Service Excellence (CRP RISE) Award. She has significantly increased clinical trial participation, expanded early screening efforts, and supported reductions in late-stage diagnoses.
Researchers at the University of California, Davis, found that rocks on fault lines can glue themselves back together within hours after a seismic event. This discovery challenges current models of fault behavior and suggests that cohesion may play a crucial role in major earthquakes.
A novel nanogel technology has been developed to kill drug-resistant bacteria, including Pseudomonas aeruginosa and Escherichia coli, with high selectivity and efficiency. The technology uses a heteromultivalent nanogel that binds to specific proteins on the bacterial surface, disrupting the membrane and leading to rapid bacterial death.
A new MIT study reveals that temporarily anesthetizing the retina of the amblyopic eye can restore its neural connections and improve vision in adulthood. The treatment, which has been shown to be effective in infancy and early childhood, may have promising clinical potential for adults with amblyopia.
Many bird species can learn to comprehend vocal signals, including gulls recognizing mates and songbirds eavesdropping on neighbors. Comprehension learning is more widespread than usage learning in birds.
Researchers found that dogs with stronger ADHD-like traits were slower to learn new information, but improved with repetition and sufficient sleep. The studies also revealed a link between ADHD-like traits and self-control in dogs, suggesting that cognitive training and sleep can mitigate these impairments.
A study published in PLOS One found that women authors comprise just 16.5% of first authors in a dataset of 878 retracted medical papers, despite accounting for at least 41% of first authors across biomedical publications. Women were also underrepresented among last authors and had fewer multiple retractions.
A new study by Marshall University researchers found that patients undergoing knee surgery using a minimally invasive needle arthroscopy technique used significantly fewer opioids after surgery compared to those treated with standard arthroscopy. The smaller-scope approach led to less pain, better early knee function, and lower opioid ...
A recent University of Michigan study sheds light on the critical protein Sarm1, which controls both nerve breakdown and regeneration. The research found that blocking Sarm1 boosts nerve regeneration but only if it preserves a delicate balance between protection and repair.
A new study reveals that knowledge of brick building in Denmark spread through the Cistercian monastic network, likely originating from northern Germany. The research analyzed 305 brick samples and found no evidence of Italian craftsmanship.
A newly discovered orchid species in Colombia is threatened with extinction due to climate change. The 'Nasar Effect' reveals that the species' demise is foretold by the conditions that threaten it, highlighting the need for international action to curb greenhouse gas emissions and boost conservation efforts.
A newly developed tool called the DILI-Inpt prognostic score can predict which hospitalized patients with severe idiosyncratic drug-induced liver injury are unlikely to recover on their own. The scoring system outperformed existing systems in identifying patients at high risk of death and liver transplant need.