Researchers from Université de Montréal found that sleep deprivation can trigger sleepwalking in predisposed individuals. The study, published in Annals of Neurology, showed that sleepwalkers who experienced one night of sleep followed by one night of wakefulness had a significant increase in behavioral episodes.
A team of Canadian and French researchers has identified the TDP-43 gene as a significant cause of ALS (sporadic amyotrophic lateral sclerosis), a neuromuscular disorder affecting motor neurons. The study, published in Nature Genetics, found that up to five percent of ALS patients have genetic mutations in this gene.
A study found that hyperactive girls are more likely to experience serious adjustment problems in adulthood, including smoking, poor job performance, and abusive relationships. The research suggests that early intervention programs targeting hyperactivity in elementary school may be crucial in preventing these issues.
Researchers at the University of Montreal developed a new approach to model RNA structure by using a structural alphabet. This innovation allows for more accurate predictions of RNA 3D structures from sequence data, with implications for studying RNA viruses and identifying microRNAs.
A Canadian-US research team has solved a major genetic mystery: how a protein in some people's DNA guards against killer immune diseases like HIV. The discovery of FOX03a offers promise for HIV vaccine development and treatments for other immune diseases, such as cancer and rheumatoid arthritis.
Researchers at Sainte-Justine Hospital and Université de Montréal have identified the CD36 receptor as the key cause of dry AMD. This discovery brings hope for new therapies to treat the blinding eye disease, which affects 30 million people over 50 worldwide.
Researchers from Université de Montréal and Cary Institute found that commercial fishing plays a declining role in removing man-made nitrogen from coastal waters. Nitrogen-rich fertilizer run-off has increased nitrogen levels in coastal ecosystems, causing excessive plant growth, lack of oxygen, and reduced fish populations.
A research team led by Dr. Alexandre Prat has identified a new therapeutic target for multiple sclerosis, ALCAM/CD166, which plays a major role in the migration of immune cells to the brain. The study suggests that blocking this molecule could dampen neuroinflammation and decrease lesions characteristic of MS.
Researchers have uncovered multiple new genetic risk factors for systemic lupus erythematosus (SLE), a disease affecting joints, kidneys, heart, lungs, brain, and blood. The study found associations with three genes: ITGAM, KIAA1542, and PXK.
Researchers at McGill University and Université de Montréal found that depression and anxiety can double a patient's chances of repeated heart ailments. Patients with coronary artery disease who had major depression or anxiety were more likely to experience cardiac events over two years.
A research team led by Andrea D. Bianchi discovered a way to control superconductivity in a material by applying a magnetic field, leading to a better understanding of the phenomenon and potential applications in energy storage and transmission.
The CARTaGENE project aims to advance population genomics research in Quebec with $34.5M funding. The project will provide resources and infrastructure for researchers to study genes responsible for disease, improving diagnosis, treatment and prevention.
A new study by Dr. Jacques Lacroix found that a restrictive transfusion strategy can be as safe as a liberal strategy in stable, critically ill children without increasing adverse outcomes. This approach reduced the need for transfusions and improved health care outcomes for pediatric ICU patients.
A consortium of Canadian and American researchers have identified three major genetic risk factors for Crohn's disease: PHOX2B, NCF4, and ATG16L1. These findings highlight biological pathways not previously thought to play a role in the disease, including altered reactive oxygen species production and autophagic processes.
A new study has discovered a way to identify cells that will cause graft-versus-host disease (GVHD) in blood cancer patients. This breakthrough allows for more reliable testing of donor T cells and personalized medicine approaches, potentially saving thousands of lives.
Scientists have developed a model of the phagosome using systems biology approach, facilitating study of its function and interactions. The model may lead to better understanding of infectious disease processes and development of new strategies to fight pathogens.
Researchers have discovered a genetic risk factor for inflammatory bowel disease (IBD) that may confer protection against Crohn's disease and ulcerative colitis. The study highlights a major inflammatory pathway and identifies potential targets for therapies, including the manipulation of IL-23 pathway.
A new study at the Université de Montréal found that caffeine taken before a night shift or studying significantly hurts recovery sleep the next day. Caffeine makes daytime sleep episodes too shallow to override the biological clock, reducing sleep efficiency and duration.
A new study has discovered that people with tone deafness lack white matter in the right inferior frontal gyrus, a key area for musical skills. The findings have implications for understanding normal music acquisition and diagnosing this lifelong disability.
An international team analyzed human genetic variation within the major histocompatibility complex (MHC), a critical immune region. The study provides a detailed map of MHC genetic variability, laying the foundation for future research into the genetic roots of immune-related diseases.
Researchers at Université de Montréal discover that mystical experiences are mediated by several brain regions, contradicting theories of a specific 'God spot'. Fifteen cloistered nuns underwent fMRI scans while reliving mystical experiences, revealing a dozen active brain regions.
Researchers from the Université de Montréal have identified a defect in the immune response to HIV and found a way to correct it. The team successfully stimulated a protein that prevents the virus from making immune system cells dysfunctional, opening new prospects for therapeutic strategies.
Researchers at the University of Montreal have identified defective immune cells as a primary cause of fungal infections, such as candidiasis, in HIV patients. This discovery could lead to more effective treatments for these debilitating conditions.
Researchers at the University of Montreal have developed a high-performance OLED on a new electrode material, enabling flexible displays. The technology uses carbon nanotube sheets, which exhibit flexibility, transparency, and conductivity, making them suitable for various display and lighting applications.
A Université de Montréal study found that boys identified as hyperactive, fearless, and not prosocial at age six are 6 times more likely to join a deviant peer group. Family adversity also increases the risk of early gang affiliation.
Research reveals that autistic individuals' intelligence is often misjudged using Wechsler scales, which require oral language skills. However, Raven's Progressive Matrices (RPM) tests show that autistics can excel in high-level abstract reasoning and problem-solving, indicating a more accurate assessment of their intelligence.
A research team at the University of Montreal has developed a cancer-curing therapy using T-lymphocytes, which recognize and destroy abnormal cells. The treatment targets specific antigens found on cancer cells, producing interferon gamma and perforine/granzyme to eradicate tumors without causing side effects.
A Canadian-led study published in The New England Journal of Medicine found that amnioinfusion does not reduce the risk of meconium aspiration syndrome. Meconium aspiration syndrome is a rare but serious neonatal lung condition caused by inhaling a mixture of meconium and amniotic fluid during labor.
Researchers in Montreal have made a groundbreaking discovery about the genetic basis of memory. They found that the GCN2 protein inhibits long-term memory storage, preventing new information from being stored for extended periods.
Researchers at Université de Montréal found that chronic exposure to both noise and carbon monoxide in the workplace significantly contributes to increased hearing thresholds at high frequencies. Workers with 25-29 years of noise exposure were particularly affected.
Researchers from CANVAC, a Canadian network of immunology and virology experts, have developed a new method to assess thymus function using only blood samples. They found that HIV-infected individuals experience decreased thymic function in the first months after infection, leading to lower T-lymphocyte production.
At Université de Montréal, researchers demonstrated real-time monitoring of ubiquitination on living cells using the BRET technique, shedding new light on the role of ubiquitin in protein degradation. This breakthrough has significant implications for understanding health and developing targeted therapeutic molecules.
Researchers at Université de Montréal found that diabetes patients are three times more likely to develop liver cancer and twice as likely to get pancreatic cancer. The study analyzed data from over 3,000 cancer patients and healthy individuals.
A Université de Montréal study reveals that early- and late-onset blind subjects excel in spatial hearing tests, distinguishing sounds from ambient noise. This improvement may stem from increased time spent developing the sense of hearing and compensatory cortical adaptations.
The Université de Montréal has received a $11.7 million grant from the Bill & Melinda Gates Foundation to develop advanced training programs, policy research leadership centers, and specialist networks for reproductive health in French-speaking sub-Saharan Africa.