A team of researchers at Columbia University has developed a multi-organ chip that mimics the process of cancer cells spreading to other organs, a critical phase of metastasis. The chip allows scientists to investigate cancer cell-tissue interactions in detail, revealing molecular pathways and therapeutic targets for metastasis.
Columbia researchers have developed a new technique to capture electrical activity and mechanical motion within the heart using cardiac ultrasound images. This technology allows for early detection and risk assessment of Mitral Valve Disease and arrhythmias, transforming care for those suffering from these conditions.
Researchers built a simple neural network that mimics the brain's processing of visual information, revealing a key role for inhibitory neurons in fine-tuned control. The findings suggest a revised understanding of how the brain processes and represents information.
A new technique uses a single image to forecast solar panel energy production and maximize output. The method estimates the amount of energy that will be produced based on the angle of the sun, shadows, reflections, and weather patterns, allowing for more accurate placement and optimization of solar panels in urban areas.
Researchers propose using electric vehicles as a backup power source for tropical cities plagued by short-lived thunderstorms. By connecting cars to the grid, they can absorb energy shortages and recharge when the sun returns. This approach reduces transmission line loads and stabilizes the grid.
A new RNA therapy has been developed to enhance the heart's own ability to protect and repair itself after a heart attack. The therapy, which involves injecting particles into the arm, significantly reduced scarring and improved heart function in lab experiments, offering a potential breakthrough for heart patients.
Researchers at Columbia University have developed a new gel electrolyte that overcomes challenges in anode-free lithium batteries by selectively repelling lithium salts. This design enables the formation of an efficient protective layer on the lithium surface, improving battery life and thermal stability.
Researchers at Columbia University have developed a faster, cheaper, and more environmentally friendly way to extract lithium. The new method uses temperature-sensitive solvent to extract lithium directly from brines found in deposits across the world.
Researchers at Columbia University develop a robot that can learn facial lip motions through observational learning, enabling it to articulate words in various languages and sing songs. The robot's ability to move its lips in sync is expected to improve with time and practice, paving the way for more holistic robot communication.
Researchers at Columbia University developed an inhalable nanotherapy called BEAT that delivers two therapeutic proteins to the lungs to target cancer cells. The treatment showed better retention in the lungs and dramatically suppressed tumor growth compared to a systemically delivered approach.
A new generation of brain-computer interface offers high-throughput information link to and from the brain, transforming treatment possibilities for neurological conditions like epilepsy and ALS. The single silicon chip implant is orders of magnitude faster and smaller than today's state-of-the-art devices.
Researchers at Columbia University have introduced metasurfaces to 2D materials, allowing for the enhancement of nonlinear optical properties and the creation of entangled photons. The technique, developed by Jim Schuck's team, shrinks nonlinear platforms to just 160 nanometers while maintaining high efficiency.
Researchers at Columbia University School of Engineering and Applied Science have discovered that a thin-film metallic resistor used to thermally tune photonic devices can also measure temperature. This finding may help integrated photonics reach its full potential by eliminating the need for bulky external temperature sensors.
Researchers at Columbia University have created a novel approach to producing hydrogen from water electrolysis, utilizing ultra-thin, PFAS-free oxide membranes. This breakthrough reduces the industry's reliance on toxic chemicals and enhances energy conversion efficiency, paving the way for a cleaner and cheaper source of hydrogen.
Researchers at Columbia University have developed a way to create powerful frequency combs on a single chip, allowing for dozens of parallel data streams. This breakthrough enables compact and cost-effective solutions for data centers, portable spectrometers, and other applications.
Researchers at Columbia University School of Engineering and Applied Science developed a novel way to use light to control tissue folding in live embryos. By manipulating proteins that generate mechanical forces, they can now study 3D tissue biology outside developing embryos or build and control tiny machines made out of living biolog...
A new platform combines bacteria and viruses to target cancer cells. The system hides a virus inside a tumor-seeking bacterium, smuggling it past the immune system and unleashing it inside cancerous tumors.
Researchers predict the existence of a material with hybrid thermal properties, which remains constant over temperature changes. This discovery could advance understanding of materials that manage extreme temperatures and reduce carbon emissions in steel production.
Columbia engineers design specialized ADC chips to capture electrical signals in the ATLAS detector, capturing details that no existing component could reliably record. The resulting design is resilient enough to withstand harsh conditions at LHC for over a decade.
Researchers designed a hydrogel system using milk-derived extracellular vesicles as both bioactive cargo and structural building blocks, enabling tissue engineering and regenerative medicine applications. The yogurt EVs promote healing and tissue regeneration without additional chemical additives.
Scientists at Columbia University have developed a process called 'Robot Metabolism' that enables machines to absorb and reuse parts from other robots or their surroundings. This new paradigm allows robots to physically sustain themselves, grow, adapt, and repair using materials from their environment or from other robots.
A new approach uses DNA to fabricate targeted 3D nanoscale structures via self-assembly, allowing for complex designs and parallel assembly. The method enables significant time- and cost-savings compared to traditional top-down strategies.
Columbia Engineering researchers have developed HyperQ, a novel system that enables multiple users to share a single quantum computer simultaneously through isolated quantum virtual machines. This approach brings quantum computing closer to real-world usability, promising faster scientific discoveries and more practical use of limited ...
Researchers at Columbia University have developed an AI algorithm that can accurately determine the atomic structure of materials with minimal sample size. The technique uses diffusion generative modeling to augment the diffraction data from nanocrystals, enabling near-perfect reconstruction of the crystal's atomic-scale structure.
Researchers found that the brain's visual system adapts in real-time to make sense of information, depending on current tasks. This challenges traditional views and opens new approaches for designing AI systems with adaptive capabilities.
A new study by Columbia University researchers reveals that 75-80% of plastics, known as semicrystalline polymers, break down into hazardous micro- and nanoscopic fragments. These fragments can persist in the environment for centuries and cause significant damage to living things.
Researchers at Columbia University School of Engineering and Applied Science have developed a new biologically inspired bottom-up way for 3D electronics to build themselves using DNA. The technique allows for the creation of complex structures with nanoscale precision, which could lead to more powerful and dense electronic devices.
Researchers develop a groundbreaking 3D photonic-electronic platform that achieves unprecedented energy efficiency and bandwidth density for AI hardware. The innovation addresses critical challenges in data movement, enabling faster and more efficient AI technologies.
Researchers at Columbia University developed a way for robots to autonomously model their own 3D shapes using a single camera, enabling them to understand and adapt to their movements. This breakthrough allows robots to overcome damage to their bodies, making them more reliable and resilient for various applications.
Researchers have identified a unique population of T cells that play a critical role in successful treatment of relapsed acute myeloid leukemia. A healthier immune environment in the bone marrow supports these cells and their cancer-fighting abilities.
Researchers have developed a method to create photon pairs that achieves higher performance on a much smaller device using less energy. The new device, measuring just 3.4 micrometers thick, has the potential to enable significant gains in energy efficiency and technical capabilities of quantum devices.
Researchers create nanosensors that can measure piconewton and micronewton forces remotely using light, enabling multiscale sensing capabilities. These sensors operate in previously inaccessible environments with benign infrared light, revolutionizing technologies from robotics to medicine and space travel.
Researchers will build a wireless bioelectronic device, named BIOSYNC, to regulate appetite through physiological satiety pathways. The device aims to produce two peptide therapeutics simultaneously with reduced side effects and better adherence to therapy.
Researchers have created a new electrolyte that enhances the energy density and power density of intermediate-temperature K/Na/S batteries, enabling them to operate at lower temperatures while achieving maximum possible energy storage capacity. This breakthrough could provide a stable and reliable power supply from renewable sources.
A team of researchers from Columbia University and Harvard University report that autoantibodies alone directly affect heart function in lupus patients. The study identified four autoantibodies that may directly affect the heart muscle, potentially leading to new therapeutic strategies.
Researchers at Columbia University have developed a biomimicry-inspired device that nearly doubles the strength of rotator cuff repairs, reducing the risk of re-tearing. The device, made from a biocompatible resin, is designed to grasp soft tissues without tearing and can be customized to individual patients.
Researchers developed a soft fabric necklace called Joey to monitor Kangaroo Mother Care practices with preterm infants. The device tracks vital signs and estimates KMC duration with an average accuracy of 96%, providing early detection of potentially life-threatening issues.
Researchers at Columbia University and colleagues have developed a new method to synthesize large-area graphene without oxygen, leading to reproducible and high-quality samples. The technique eliminates trace oxygen, which has previously affected the growth rate and quality of graphene.
Columbia Engineers employ nuclear magnetic resonance spectroscopy to examine lithium metal batteries. Their findings may help design new electrolytes and anode surfaces for high-performance batteries, addressing the challenges of commercializing lithium metal batteries.
Researchers at Columbia Engineering have developed a technique to modify 2D materials using lasers, creating tiny nanopatterns that can capture quasiparticles called phonon-polaritons. This method uses commercially available tabletop lasers and doesn't require an expensive cleanroom or etching equipment.
Researchers at Columbia University developed BeatProfiler, an AI-based software that automates the analysis of heart cell function from video data, significantly speeding up the process and reducing errors. The tool can accurately analyze cardiomyocyte function, outperforming existing tools by being faster and more reliable.
A team of Columbia engineers created Emo, a robotic face that makes eye contact and uses AI to anticipate and replicate human smiles. The robot can predict facial expressions and execute them simultaneously with humans, reducing disingenuous interactions.
Researchers are developing a living knee replacement made from biomaterials and human stem cells, including patient's own cells. The goal is to create a permanent solution for patients with advanced OA where conventional knee replacements fail.
Researchers have developed an all-optical device on a tiny photonic chip that generates high-quality, ultra-low-noise microwave signals using a single laser. The compact device has the lowest microwave noise ever observed in an integrated photonics platform.
Researchers at Columbia University discovered that brain waves move from back to front while forming new memories, but reverse direction when recalling information. The study's findings advance fundamental neuroscience research and may lead to diagnostic and therapeutic approaches for memory-related disorders.
Columbia University engineers have developed a novel approach to create highly conductive single-molecule devices using direct metal-metal contacts and light control. The discovery opens up new possibilities for designing smarter electronic components.
Researchers at Columbia University School of Engineering and Applied Science have developed a new inhalable therapy that delivers IL-12 mRNA directly to the lungs, demonstrating potential as a tumor suppressor. The therapy uses nanobubbles called exosomes to deliver the mRNA, which kickstarts lung immune cells to fight cancer.
Researchers built a new AI that challenges traditional fingerprint comparison methods, revealing similarities between fingerprints from different fingers of the same person. The system achieved high accuracy in detecting intra-person fingerprint matches, potentially increasing forensic efficiency by tenfold.
Researchers at Columbia University paired laser light with crystal lattice vibrations to boost the nonlinear optical properties of hexagonal boron nitride (hBN), a stable 2D material. The team achieved over a 30-fold increase in third-harmonic generation, generating new frequencies and efficiently producing optical signals.
A multi-institutional team led by Columbia Engineering aims to develop AI systems that better communicate with people and react to unforeseen circumstances. They will integrate causal modeling techniques with traditional AI decision-making methods, focusing on real-world applications in public health and robotics.