A new smartphone app has been shown to significantly improve sex life and delay ejaculation in men with premature ejaculation. The app, developed by urologists and psychologists, teaches men therapeutic techniques and exercises to manage arousal and control ejaculation.
A young female fisher traveled 118 kilometers from Durham to the White Mountains in New Hampshire, the longest recorded dispersal for the species. This journey, documented over winter with deep snow, underscores the fisher's adaptability and highlights the need for further research into movement patterns.
The photonics technology can detect molecular signals long before symptoms emerge, enabling earlier diagnosis and treatment. The technology uses nanomaterials and photonics to interact with microRNAs and detect cancer signals.
A new RNA therapy has been developed to enhance the heart's own ability to protect and repair itself after a heart attack. The therapy, which involves injecting particles into the arm, significantly reduced scarring and improved heart function in lab experiments, offering a potential breakthrough for heart patients.
The new law, House Bill 1266, guides curriculum and teacher training to prepare students for a data-rich world. By integrating data science across K–12 subjects, Indiana aims to develop critical thinking and problem-solving skills for future success.
Researchers at Rice University developed a safe bioelectronic sensor using naturally occurring polymer chitosan to effectively communicate with bacteria. The system uses a hydrogel to trap bacteria near an electrode, generating a stable electronic current when exposed to target substances.
A new University of Arizona study found that exposure to certain pesticides before pregnancy is associated with lower Apgar scores, a measure of newborn health. The study suggests that pesticides can affect the next generation, highlighting the importance of regulating pesticide use to improve maternal and child health.
Researchers transformed waste into high-performance porous carbon materials for soil and water conservation. The study identified top-performing materials from agricultural wastes, which exhibited high surface areas and favorable pore structures, enhancing adsorption capacity and water retention.
Insilico Medicine's inclusion in the Hang Seng Index and Stock Connect program is expected to enhance stock liquidity and market attention, strengthening the company's capital market influence. The company has achieved multiple drug development milestones, including 12 IND-enabling programs and preclinical candidates ISM0676 and ISM5059.
Insilico Medicine's Alex Zhavoronkov chairs precision aging discussion and presents Luminary Award to OpenAI president Greg Brockman. The company's AI-driven approaches accelerate drug discovery and advance precision medicine for aging and age-related diseases.
Researchers at Duke University have developed a technique using microbubbles and ultrasound to deliver large cancer drugs into cells, causing them to self-destruct. The technology, called SonoPIN, shows promise in precisely delivering therapeutics to cancer cells with minimal off-target effects.
Researchers found that seniors are willing to travel more than an hour for routine or specialized medical care, but this willingness varies by socioeconomic status, mobility, and location. The study's findings have implications for telehealth expansion and transportation policy, suggesting that programs offering ride services, improved...
Engineers from the University of Colorado Boulder have discovered the mathematical rules that fireflies follow to sync up their flashes in a South Carolina swamp. The team's findings could lead to new designs for robots that move in swarms and help scientists understand other examples of synchrony in biology.
A study in ferrets demonstrates that immunity to two proteins on the surface of the influenza virus can reduce transmission and viral evolution. Targeting both hemagglutinin and neuraminidase proteins can effectively curb the spread of the virus, with transmission rates dropping by half in animals with immunity to both.
Researchers at Albert Einstein College of Medicine have developed a new strategy to engineer immune cells that prolong their effectiveness, addressing a major limitation of current treatments. The new method generates longer-lasting immune cells that provide more sustained control of human blood cancers and suppression of HIV-infection.
A systematic review found a significant association between excessive smartphone use and eating disorder symptom severity in young people, including disordered eating and food addiction. The study highlights the need for early intervention strategies to address excessive phone use in young people displaying eating disorder symptoms.
The updated guideline consolidates evidence-based recommendations for managing dyslipidemias, offering a comprehensive approach to lower risk of atherosclerotic cardiovascular disease. The guideline recommends earlier intervention through healthy lifestyle changes and considers the use of a new cardiovascular disease risk calculator, P...
Researchers have confirmed the existence of a long-theorized molecule in oxidation, which has implications for atmospheric chemistry, biochemistry, and medicine. The discovery was made using a unique mass-spectrometric technique and has significant implications for understanding reaction steps and products in oxidation processes.
Researchers used afterimages to measure brain predictions of visual consequences of eye movements, finding that predictions are accurate but subject to systematic errors. The brain's efference copy helps predict visual shifts, but this prediction falls short of the actual eye movement's consequences.
A new framework, 'just-shoring,' aims to shift focus from competition and security to the rights and interests of local communities whose lands are most at risk. The approach prioritizes accountability and transparency, giving communities a legal right to co-govern throughout the mineral lifecycle.
The American Meteorological Society and partners urge reinstatement of climate science chapter in judicial reference manual, citing concerns over public access to scientific knowledge. The statement emphasizes the overwhelming agreement among experts on climate change, its impacts, and human activities as primary drivers.
A new study reveals that selfish chromosomes exploit the Overdrive gene to destroy rival sperm, boosting their chances of passing into the next generation. The gene acts as a quality control checkpoint during sperm development, normally eliminating abnormal sperm cells, but selfish chromosomes hijack the system to kill competitors.
The study found that using heavy water in the electrolyte solution significantly increased energy output from the yarns, with up to 2.5 times higher peak electrical power and 1.8 times more energy per stretching cycle. The energy conversion efficiency reached 9.5%, higher than any other previously reported twistron harvester operating ...
The 2025 update provides 5 overarching principles and 9 individual recommendations for managing rheumatoid arthritis, emphasizing patient-centered care and simplifying clinical approaches. The update prioritizes treatment targets, monitoring frequency, and the role of methotrexate, glucocorticoids, biologics, and JAK inhibitors.
Kalinin's work is reshaping how new materials are designed, tested, and studied, enabling researchers to predict promising new materials computationally. He has developed machine learning-driven systems that can synthesize and characterize new materials at unprecedented speed.
A tropical insect has been found to change color from hot pink to green within a fortnight, resembling the young leaves of rainforest plants. This remarkable adaptation allows the insect to blend in with its surroundings, suggesting a finely tuned survival strategy.
Researchers at the University of Arkansas have developed a sulfide coating that significantly increases the life, power, and safety of lithium batteries. The coating, applied to nickel-rich cathodes, protects the battery electrolyte from decomposition and stabilizes the interface, leading to improved performance and longer lifespan.
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) and the Global Lung Function Initiative (GLI) have agreed on diagnostic criteria for COPD, aiming to improve diagnosis and treatment. The new guidelines will help reduce the number of undiagnosed cases and promote the use of spirometry tests.
A new study finds that the North Atlantic's exceptional warmth played a key role in the Valencia DANA storm's intensity, with precipitation 40% lower without it. The research highlights the importance of oceanic context in extreme weather events, reinforcing the need for global climate simulations.
Scientists discovered a 4-meter-long Polycotylus fossil with a huge tooth embedded in its neck vertebrae, suggesting a violent attack by an enormous bony fish called Xiphactinus. The fossil's internal structure was analyzed using CT scanning, revealing a three-dimensional model of the tooth and its attacker.
A new study found that bilingual consent forms significantly improve cancer treatment understanding among people with limited English, with understanding rising from 35% to 60%. The study, published in Supportive Care in Cancer, examined the impact of different translation approaches on cancer treatment understanding among Bengali- and...
Researchers investigated the Mississippi River's hydrological trends, ocean carbon storage, and gender dynamics in flood mortality. A study found that precipitation increases, but soil moisture decreases, while high-resolution models reveal stronger Southern Ocean carbon absorption. Additionally, data showed men are overrepresented in ...
Researchers found that cortisol significantly worsens orientation in individuals, particularly in environments without landmarks. The brain's internal GPS system, grid cells, lose function under stress, leading to impaired navigation.
Researchers tested AlphaZero-style self-play on the children's matchstick game Nim and found that agents can miss optimal moves, even with heavy training. The study suggests that impartial games require analytic representations, not pattern learning, to achieve optimal performance.
A cohort study found that 180-minute drives from a donor care unit are common, highlighting the need to improve system efficiency and donation outcomes by opening additional DCUs in acute care hospitals and expanding donor transport across existing boundaries
A mixed-methods cohort study found daily living impairment is linked to slower recovery in older adults post-surgery. Targeted interventions, such as preoperative education and caregiver support, can optimize recovery experiences for both patients and caregivers.
A genetic mutation found in high-altitude animals may help regenerate myelin sheath and repair nerve damage in conditions like MS and cerebral paralysis. The mutation increases production of a metabolite that promotes myelin production and maturation.
Researchers have discovered that vitamin B2 protects cancer cells from ferroptosis, a type of programmed cell death. By targeting vitamin B2 metabolism, cancer cells may become more susceptible to ferroptosis, paving the way for new cancer therapies.
Researchers found that treating severe fetal megacystis with a vesicoamniotic shunt in the first trimester can improve survival rates and kidney function. In the study, 75% of children were born alive and 68% survived their first year of life, with most showing normal or only slightly impaired kidney function.
A medieval individual buried in the Menga dolmen in Andalusia has been found to have a mixed ancestry, with uniparental lineages typical of European populations and mitochondrial DNA shared with modern North African individuals. The study sheds light on the genetic diversity of Andalusian society during the Middle Ages.
MicroEnsemble wins AI Weather Quest, demonstrating improved sub-seasonal weather forecasting accuracy. The team uses AI technologies to post-process state-of-the-art forecasts, achieving consistent performance across various weather variables.
GSI/FAIR's new Galactic Cosmic Ray simulator enables researchers to better understand radiation doses and control effects in human tissue and technical components. The simulator replicates the GCR exposure in a lightly shielded habitat, providing a crucial tool for space radiation research.
Recent discoveries have shed light on gene expression control in tumor growth, revealing the critical role of epigenetic marks and genomic imprinting. The findings have significant implications for cancer treatment, as they suggest that disrupting the tumor's access to neural signaling may halt its growth.
Researchers found that fedratinib inhibits BRD4, activating a transcriptional pathway that induces ERMCS formation and causes structural changes in organelles. The study provides a potential therapeutic avenue for diseases like neurodegeneration, obesity, and cancer.
A new study suggests that exercise can improve mental sharpness and reduce cognitive decline in cancer patients undergoing chemotherapy. Researchers found that patients who exercised while on chemotherapy maintained their daily step goals and reported improved mental clarity, while those who did not exercise experienced significant dec...
Researchers explored using CDK4/6 inhibitors to treat PDAC by targeting RB1, which is often inactivated by oncogenic KRAS. This approach showed promise in inducing cellular senescence, but further combination therapy is needed for therapeutic benefit.
Researchers discovered that intrinsically disordered regions (IDRs) retain function through interplay of linear motifs and chemical characteristics, not just conserved sequence blueprints. The study found that short binding motifs and overall chemical context are crucial for protein function.
Researchers have identified and resolved molecular bottlenecks to produce doxorubicin, a vital chemotherapy agent, resulting in a 180% increase in production. This breakthrough enables cost-effective manufacturing of essential antibiotics and anti-cancer agents, promising a cleaner and more reliable supply of life-saving medicines.
A novel design strategy has been proposed to efficiently synthesize methanol from CO2, decoupling active sites through a strong metal-support interaction. This approach enables a significant increase in methanol yield compared to conventional catalysts.
Researchers at Brown University develop a way for robots to use inputs from both human language and gesture to reason about object location. The approach, which incorporates insights from dog behavior, achieved an 89% success rate in finding the correct object in complex environments, outperforming other methods.
Researchers found that D, L-buthionine-(S, R)-sulfoximine (BSO) replicates the anti-obesity effects of sulfur amino acid restriction without causing bone loss in male mice. The study suggests BSO as a promising tool for dissecting the beneficial versus deleterious axes of sulfur amino acid biology.
Researchers at Tohoku University have developed a comprehensive digital materials ecosystem that integrates AI tools to streamline materials design, enabling faster and more accurate discovery of new materials. The ecosystem uses databases, AI, and scientific workflows to predict material properties and optimize design processes.
The study investigates ocean-atmosphere variability under Miocene-like high-CO2 conditions to evaluate climate-model performance in warm climates. ENSO variability peaked under 3×CO2 and was damped under 4×CO2, with El Niño events exhibiting longer mean duration than La Niña events.
Researchers engineer T cells to express specific TCRs, demonstrating that antigen recognition drives phagocytosis and identifying key regulatory parameters, such as antigen density. The study's findings offer mechanistic insights and translational promise for immunotherapy.
A study led by Dr. Edward Ricemeyer reveals that the Amazon molly maintains its genome through gene conversion, which helps remove harmful mutations and allows natural selection to keep working in the absence of recombination. This process empowers natural selection in a clonal fish species, maintaining overall genome integrity.
Scientists have developed a novel 2D multiferroic metal, bilayer CrTe2, with intrinsic room-temperature multiferroicity and strong magnetoelectric coupling. The material exhibits reversible out-of-plane polarization and demonstrates 'electrical writing and magnetic reading' capabilities.
A new photocatalyst design using machine learning interatomic potential calculations has successfully identified suitable dopants for a novel tin oxide material. The resulting aluminum-doped material produces 16 times more hydrogen under visible light than the undoped material, paving the way for next-generation clean energy applications.
Researchers from Institute of Science Tokyo created a system that turns spoken impressions into personalized makeup colors, combining AI and projection technology. The system shows realistic makeup previews on real skin under natural light, making it easier for users to find suitable colors.
Moons around free-floating planets can keep their water oceans liquid for up to 4.3 billion years due to dense hydrogen atmospheres and tidal heating. This allows for stable habitats for complex life to develop and could significantly broaden the spectrum of possible environments that could harbor life.
Researchers found penicillin-streptomycin increases macrophage stiffness and rewires ECM mechanosensing, impairing immune function and suggesting potential off-target effects in clinical use. The study highlights the need to re-evaluate common cell culture reagents through a mechanobiological lens.
Researchers at Kyoto University discovered that bees favor flowers with early visitors over color, even when the latter has an initial disadvantage. This finding indicates that social information plays a crucial role in pollinator choice, and flowers that secure early visitors may gain a lasting advantage.
Researchers investigated temperature-dependent sex determination in leopard geckos, finding that temperature influences sex development during a specific window of embryonic development. Early genetic changes, including the activation of male and female developmental pathways, occur before physical differences become apparent.
A Chinese study reports a 100% technical and clinical success rate for robot-assisted brain angiography, with median procedure times 11 minutes shorter than manual angiography. No added radiation or complications were observed, showcasing the feasibility and safety of the YDHB-NS01 system
Researchers have discovered a new chemical reaction that can be used to modify anti-tumor compounds, produce recyclable plastics, and develop new materials. The 'trisulfide metathesis reaction' is a clean, efficient method that can be completed within seconds.
A study by the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona establishes the principles for modelling post-growth scenarios, pointing to the need for targeted demand-side measures and investments in low-carbon technologies. The research highlights the potential for post-growth to achieve pos...
Researchers developed predictive AI models that identified patients at risk of intimate partner violence from their medical records, years before they enrolled in care. The models achieved high accuracy and could detect IPV up to four years before patients sought care.
A study by Florida Atlantic University researchers has uncovered the impact of stress on wild songbirds, finding that even mild challenges can alter the gut microbiome, leading to changes in health indicators such as beak color and stress hormone levels.
Researchers developed an AI tool to predict patients at risk of intimate partner violence, using data from medical visits. The tool achieved high accuracy in detecting IPV among patients, with the multimodal fusion model outperforming others, detecting risk 88% of the time.
Researchers discovered a freshwater alga that captures far-red light for photosynthesis by rearranging ordinary chlorophyll. This unique strategy allows the alga to thrive in shaded forests and murky waters, making it resilient in tough environments. The findings have practical implications for sustainable bioenergy production and may ...
Scientists extracted thousands of years' worth of air pollution from a 9.5-meter ice core, recording medieval mining, fires, and volcanoes. However, global warming is destroying this frozen archive, and researchers warn that it's a race against time to capture critical climate information.
Researchers at Osaka Metropolitan University discovered how shifting electric fields control light-emitting efficiency in devices like LEDs. By probing electron spin resonance, they found optimal electric field conditions for efficient recombination, leading to higher electroluminescence efficiency.