A new study describes phage therapy as a game-changing solution to combat multi-drug resistant Pseudomonas aeruginosa infections. Researchers found that sequential administration of phages and antibiotics can clear infection and re-sensitize bacteria to antibiotics.
The study of 5,951 women aged 63 to 99 found that higher levels of physical activity and lower amounts of sedentary time were associated with reduced heart failure risk. Promoting regular physical activity and limiting sedentary time may be a prudent strategy for primary prevention of heart failure in older women.
Researchers developed a portable, droplet-based millifluidic device to monitor patients in the critical first days after surgery. The device measures drainage fluid's alpha-amylase activity in real time, reducing test duration from six hours to two minutes.
Researchers analyzed tissue and fecal samples from 90 stranded marine mammals to study the distribution of toxic elements. The study found that Risso's dolphins and short-finned pilot whales had high concentrations of mercury, cadmium, and lead, while dwarf sperm whales had low levels.
Kun Luo uses atomic structure models to uncover novel materials and their properties, such as superhardness and conductivity. His research has led to the discovery of a new material called Gradia, which could be applied to new technologies.
A recent study reveals that converting rainforests to plantations erodes and restructures food webs, fundamentally changing their functioning. The researchers found that energy flows differently in plantation ecosystems compared to rainforests, with a greater emphasis on invasive species and reduced predation.
A groundbreaking research breakthrough has led to the development of the world's most efficient quantum dot (QD) solar cell, retaining its efficiency even after long-term storage. The newly-developed organic PQD solar cells exhibit both high efficiency and stability simultaneously.
A new study has found that heavy alcohol use and illicit opioid use are linked to a higher risk of falls and fractures among people living with HIV. The study suggests the need for targeted clinical screening and interventions to prevent falls and related injuries, particularly among populations already at risk.
Researchers at KIT's Institute for Advanced Membrane Technology found that the interplay of hydrodynamic forces, friction, and forces of attraction and repulsion affects adsorption in membrane nanopores. This study provides basic findings with respect to water processing and may benefit ultra- and nanofiltration processes controlled by...
A new method combines a tri-channel chiral metasurface with a deep convolutional neural network to analyze polarizations, achieving fast, robust, and accurate measurements. This approach supports high spatial resolution requirements and compact design, enabling diverse applications in remote sensing, astronomy, biology, and microscopy.
Researchers at the University of Manchester have developed new methods to simulate blood flow, enabling faster and more accurate modeling of vascular diseases. These advancements have the potential to transform medical treatment and device innovation, providing real-time insights during surgical procedures and improving patient outcomes.
A UCLA-led study found that a combination of telehealth coaching, peer support, and automated text messages increased PrEP uptake among younger Americans by more than doubling it. The intervention's success suggests the importance of behavioral interventions and wraparound services in supporting HIV prevention.
Researchers have introduced an optimization technique that accelerates Bayesian inference without requiring extensive user effort. This new automated method achieves more accurate results faster than another popular approach and offers reliable uncertainty estimates to help scientists understand when to trust their predictions.
The Biophysical Society recognized 10 students for their exceptional poster presentations during the annual Undergraduate Poster Award Competition. The winners are from top universities across the US and explored various biophysics topics.
A Princeton University team developed an AI model that can forecast potential plasma instabilities up to 300 milliseconds in advance, allowing for real-time adjustments to avoid reaction-ending escapes. The model uses past experimental data and demonstrates a promising approach to solving a broad range of plasma instabilities.
Scientists at CeMM Research Center have discovered a new method to mark proteins for destruction, potentially treating diseases like cancer. The technique uses 'intramolecular bivalent glues' to alter the protein's surface, triggering targeted protein degradation via ubiquitin ligases.
A research team at Children's National Hospital found that maternal mental illness contributes significantly to the death of new mothers in the US. The study highlights the need for urgent action to address this public health crisis, which is driven by a lack of access to maternity care and inadequate screening for depression postpartum.
Researchers identified a putative paclitaxel response predictive biomarker for glioblastoma and breast cancer using the whole genome CRISPR knockout screen. The biomarker candidate was validated in two independent breast cancer patient cohorts that received taxane treatment.
Researchers analyzed over 200 butterfly and moth genomes to understand their evolutionary history. They found that chromosomes have remained largely unchanged since the last common ancestor over 250 million years ago, despite the diversity seen today in wing patterns and caterpillar forms.
New research from the University of California San Diego found that men with a higher area of abdominal muscle have a greater risk of cardiac trouble. Men with the densest muscle in their abdominal cavity had about one quarter the risk of coronary heart disease later on.
A study published in PLOS ONE found that raised blood pressure has been the leading risk factor for death in Australia for three decades, contributing to at least 44% of cardiovascular disease (CVD) deaths. The research highlights the importance of prioritizing blood pressure control efforts in public health agendas.
Researchers tracked bowhead whale migrations using acoustic data, revealing shifts in winter departure times and increased summer presence in the Chukchi Sea. Climate-driven changes may push whales into shipping lanes, posing risks to both humans and animals.
A one-year interdisciplinary therapy program reduced inflammation and cardiometabolic risk in obese adolescents, improving insulin resistance and weight management. The semi-intensive model produced better results than previous intensive models, reversing hyperlipidemia and promoting energy balance.
A study found that weedy rice's promiscuity allows it to crossbreed with wild rice, enabling it to adapt and outcompete cultivated rice. This process, called adaptive introgression, has contributed to the evolution of Southeast Asian weedy rice.
Researchers developed a CRISPR RNA-editing platform to regulate immune cell metabolism, boosting anti-tumor function and sustaining T cell proliferation. The platform enables reversible changes to gene expression and can be controlled by a drug, offering a safety switch for immunotherapy treatments.
The ERC project will integrate data on plant traits from above- and below-ground levels to predict the effects of global change scenarios on plant communities. This comprehensive approach aims to shed new light on how plant communities structure and respond to environmental pressures.
Researchers identified an optimal approach that uses periods of stricter and less strict lockdowns to accompany recurring epidemic waves. They also found that small changes in key parameters can flip the optimal strategy from one extreme to the other.
Scientists identify chronic ER stress and mitochondrial damage in DM2 cells, triggering an antiviral response and autoimmune diseases. The study provides new therapeutic targets to suppress the development of autoimmune diseases in patients.
Researchers found a subducted oceanic slab that has completely overturned beneath the western Mediterranean. The discovery helps sort out the complicated tectonic structure of the region, where Africa and Eurasia are converging.
Men with low sperm count or none have a higher risk of developing cancer, including at younger ages, compared to fertile men. Families of azoospermic men have a significantly increased risk of five cancers, while families of oligozoospermic men have a higher risk of colon, bone and joint, and testicular cancers.
Scientists found a mutation in E. coli that allows it to spread further into the body and infect organs, causing life-threatening diseases. The discovery helps explain why certain types of E. coli become more dangerous and provides an explanation for emerging virulent bacteria.
Researchers have developed a novel 'nano active control platform' to control excitons and trions, providing valuable insights into the optical properties of two-dimensional semiconductors. The breakthrough discovery enables real-time analysis of nano-light properties with exceptional spatial resolution.
A survey-based study found that exposure to news clips of immigrant deaths decreased white individuals' belief in the American dream, while increasing their views on systemic racism. In contrast, Latinx individuals increased their belief in the American dream and decreased their beliefs in systematic racism.
Scientists create 'μkiss' technique for precise delivery of materials to individual cells, offering new possibilities in single-cell science and next-generation therapeutic applications. The method provides full control over location, time, and scale of material application, enabling detailed studies of cellular processes.
Researchers discovered exceptionally high levels of PFAS in birds and mammals at Holloman Lake, contaminating thousands of species. The study found that even low concentrations of PFAS can cause harm to animals and people, highlighting the need for environmental action.
A study of 1,948 U.S. adults with lifetime suicide attempts found that nearly 20% had no prior psychiatric diagnosis, raising questions about suicide risk screening limits. This finding suggests a broader population is at risk and warrants further investigation into suicidal behavior.
Researchers at University of Alaska Fairbanks have developed a new detection method that can identify landslides within minutes and determine if they pose a tsunami hazard. The method uses seismic data to estimate a landslide's location, volume, and potential impact, with the goal of issuing warnings in under 5 minutes.
Researchers at Tokyo Institute of Technology developed a 300 GHz-band transmitter that solves issues with high-frequency electromagnetic waves and offers high data rates of up to 108 Gb/s. The proposed solution features a phased-array design, low power consumption, and area efficiency.
Researchers have developed a novel biohybrid catalyst that uses an anchor peptide to oxidize polystyrene microparticles, making them degradable. The catalyst accelerates the formation of polar OH groups through reaction with Oxone, allowing for efficient breakdown and degradation of polystyrene.
Researchers found six pesticides and related compounds in kale from small farms in Maryland, but levels were much lower than a concern. The study provides insight into the safety of farm-raised greens and will help identify health risks associated with other fruits and vegetables.
A new study published in LANCET eClinicalMedicine found that regular exercise can help individuals maintain weight loss after completing medical weight loss treatment. The study showed that exercising just two hours a week can lead to better quality of life, improved mental health, and reduced fatigue.
Researchers have found a new potential therapeutic target for autoimmune diseases such as lupus and multiple sclerosis by identifying an overlooked sequence in the IκBζ protein. This sequence, known as the OCA peptide, can activate key proteins in immune cells and may help reeling in immune cells gone haywire.
A team of researchers at Max Planck Institute for Evolutionary Anthropology developed a new simulation model to study the cultural evolution of collective property rights. The model shows that these institutions critically depend on clearly defined and enforced access rights.
A University of Michigan team recalibrated traffic signals using GPS data from connected vehicles, resulting in a 20-30% decrease in stops at intersections. The system reduces costs and cuts vehicle emissions by optimizing signal patterns for changing traffic flows.
A genetic study reveals two distinct clusters of deer populations in Nara, Japan, highlighting the need for reconciliation among stakeholders. The research emphasizes the importance of careful management to address conflicts between preserving sacred deer lineage and allowing admixture for conservation.
Zero-index metamaterials (ZIMs) exhibit uniform electromagnetic field distribution over arbitrary shapes, enabling ultra-compact cloaking devices and arbitrarily shaped waveguides. Researchers have developed a highly homogeneous ZIM using high-permittivity materials, reducing its physical dimensions by threefold.
Researchers engineered tiny spinning micro-robots that bind to immune cells to study their function and aid in the design of immunotherapies. The robots mimic the role of physical force in immune cell interactions, enabling scientists to analyze large collections of immune cells with high accuracy.
Researchers have discovered a new mechanism by which oocytes remain healthy for decades without succumbing to the wear and tear that would cause other cell types to fail. The study reveals the presence of EndoLysosomal Vesicular Assemblies, specialized structures that capture and hold onto protein aggregates, rendering them harmless.
A study published by the University of Córdoba and Maimonides Institute for Biomedical Research found that a Mediterranean diet reduces levels of harmful compounds called AGEs, which can accumulate in the bodies of diabetic patients with kidney problems. This dietary pattern may mitigate kidney disease deterioration in diabetic patients.
A recent study by UNM Health Sciences researchers has found that microplastics are present in all 62 human placenta samples tested. The concentrations ranged from 6.5 to 790 micrograms per gram of tissue, with polyethylene being the most prevalent polymer found. The study suggests that microplastics may be linked to puzzling increases ...
The NSF director highlights the benefits of AI in scientific research, from accelerating discovery to automating routine tasks. He emphasizes the need for safe and accessible AI, calling for a diverse AI ecosystem that incorporates broad perspectives and problem-solving approaches.
Researchers found that Inuit residents in Nunavik had shorter survival rates for lung cancer compared to Montreal residents, despite similar disease stages. The study attributes this disparity to chronic under-resourcing of healthcare services and lack of Inuit representation in healthcare provision.
A study published in Global Change Biology found that low deep-water oxygen concentrations lead to increased algae growth and further oxygen declines. This positive feedback cycle can result in frequent algal blooms, disrupting lake ecosystems and human health.
A 15-year longitudinal study by UCLA researchers identifies an association between prenatal stress and early signs of adrenal puberty in first-born daughters. This finding adds to the understanding of fetal programming and its impact on child development.
The study successfully manipulates distinct exciton species within a hybrid monolayer WSe2-Ag nanowire structure, exhibiting high coupling efficiency with surface plasmon polaritons. This breakthrough enables precise control over light emissions and paves the way for advanced optical and quantum applications.
A new species of rare pseudoscorpion, Olpium caputi, has been discovered in French Polynesia and named after Slovak President Zuzana Čaputová. The species was collected on the island of Tahiti and is the first new record for the region.
Researchers developed a biosensor to measure hypoxanthine levels in meat, indicating freshness. The sensor achieved over 98% accuracy and was demonstrated on pork tenderloins.
A new study found that the 2021 Child Tax Credit expansion significantly reduced food insufficiency among American families, particularly those with children who experienced economic shocks during the COVID-19 pandemic. The monthly advance payments included in the expansion enabled all families to afford enough food and had a greater i...
A new study from Binghamton University finds that preannouncement marketing can positively impact stock market reactions, especially when it comes to costless approaches. The researchers analyzed 149 product launch events and found that surprise effects and information asymmetry can also play a role in shaping market expectations.
Neural stem cells developed into nerve cells when adhering to hydrogels with high positive charge, while those on lower positively charged gels became glial cells. The ability to influence differentiation could aid in nerve and glial cell regeneration and treatment of diseases like multiple sclerosis.