Scripps Research has received a significant award of in-kind compute power from the Jen-Hsun and Lori Huang Foundation to advance the adoption of AI into biomedicine. The grant will support projects building a virtual human immune system and charting the
Researchers have found that neutrophils, white blood cells, are present in many tissues during embryonic development, performing functions similar to adult neutrophils. This discovery suggests that embryonic neutrophils may have roles in tissue development and homeostasis in addition to immune defense.
Researchers at Mizzou discovered that tongue exercise can improve the activity of surviving neurons controlling tongue movement, helping them compensate as other neurons are lost. This finding offers hope for preserving quality of life for those with ALS and other motor neuron diseases.
A 16-year study found that older adults with greenery within 100 meters of their homes have a 20% lower risk of developing dementia. The study highlights the importance of preserving and enhancing greenspace in urban environments to support brain health and healthy ageing.
Research finds that 1/4 of global data centers are located in water-stressed areas, where demand exceeds supply, and this number could rise to 1/3 under a future climate scenario. Data centers use nearby water resources, which vary seasonally, and their operations can impact local water management and infrastructure.
A team at the University of Basel has identified a molecular switch that controls the sorting of recyclable cargo into transport vesicles. The small protein ARF-1 ensures efficient loading and return of cargo to the cell surface. This process, known as 'kiss-and-run,' allows cells to reuse receptors and transport proteins, and disrupti...
Researchers at McGill University's Trottier Space Institute found that the gas orbiting Sagittarius A* is rich in metals, similar in composition to the stars in its orbit. The metal enrichment likely resulted from stars that exploded and released material into the black hole's surroundings over time.
A new study reveals that afforestation and reforestation efforts face significant social and institutional challenges, including poverty, food insecurity, and weak governance. This threatens to limit the global potential for forests to capture CO2, with the biggest hurdles facing tropical countries.
Vardit Ravitsky, President of The Hastings Center, has been elected to the National Academy of Medicine for her contributions to bioethics and public health. The academy recognized her work on reproductive health, gene editing, and the use of AI in healthcare.
Charles W.M. Roberts, MD, Ph.D., was elected to the National Academy of Medicine for his groundbreaking research on cancer epigenetics and its impact on developing novel therapies for children with cancer. As St. Jude president and CEO-elect, Roberts will continue to advance the field of pediatric oncology.
Carsten Bönnemann, MD, habil., was elected to the National Academy of Medicine for his research on neuromuscular disorders and his work advancing novel therapeutics. As the inaugural chair of St. Jude's Department of Genomic and Translational Neuroscience, Bönnemann aims to address the unmet need for effective treatments for progressiv...
Thiele's five-year award supports new chelator designs to improve targeted radiopharmaceuticals for cancer diagnosis and treatment. The research aims to advance personalized medicine by improving approaches to cancer diagnosis and treatment.
A new study found that increases in risk-taking behavior in people with mild to moderate alcohol use disorder (AUD) precede increases in alcohol consumption, not vice versa. The study used gamified smartphone-based decision-making tasks to track participants' drinking behavior, cognitive control, and decision making over a 1-year period.
The SO322 expedition explores the environmental consequences of polymetallic nodule mining, revealing slow recovery and significant ecosystem disruption. Researchers investigate the effects of sediment plumes and artificial hard substrates on seabed communities, shedding light on the abyssal ecosystem's complexity and interconnectedness.
Researchers at The University of Tokyo developed a contact-engineered MoS₂ memtransistor with brain-inspired memory, enabling analog synaptic behavior and temporal ECG signal processing. The device demonstrated gradual long-term potentiation and depression, spike-amplitude-dependent plasticity, and timing-dependent conductance changes.
Researchers discovered how HSV-1 changes the brain's immune cells response to infection, potentially triggering chronic inflammation and Alzheimer's disease. The virus activates powerful antiviral defenses in microglia, which may compromise their ability to maintain a healthy brain.
A new AI model, Percival, analyzes CT scans to uncover hidden patterns in disease and potential future health risks, improving the accuracy of health assessments. The model has been trained on a diverse dataset of 350,000 people and has shown promising results in detecting chronic conditions such as atrial fibrillation and chronic kidn...
KAIST researchers developed an unmanned synthesis platform combining robots and light to automate the entire process from mixing raw materials to synthesis and analysis. The platform successfully synthesized the N-methyl pyrrole scaffold and demonstrated potential for continuous manufacturing.
A study found that PAI-1 and S100A10 are key drivers of tumor growth in the ascites microenvironment. A novel nanobody, E8, targeting PAI-1 showed therapeutic efficacy and safety in laboratory, mouse, and human tissue models, suppressing tumor growth with minimal toxicity.
Researchers discovered a previously unknown fungal GPCR that uses a peptide to detect host entry and trigger growth changes. This mechanism allows the fungus to manipulate the plant's growth and increase its chances of successful infection.
The Yangtze River pilot program showed ecological gains after 3 years, with native fish species increasing and porpoise populations thriving. Restoration pathways, such as decommissioning hydropower stations, helped revive habitats and species.
Researchers discovered DNA methylation patterns associated with treatment response in OCD, suggesting potential for personalized therapy. These epigenetic markers were linked to brain plasticity, stress responses, and immune function.
A study found that wood supported a higher abundance of hydrocarbon-degrading bacteria compared to other materials like plywood and polypropylene. The biofilms on wood exhibited greater microbial richness and continuity, suggesting it as a favorable surface for developing microbial communities associated with hydrocarbon degradation.
Researchers found that co-digesting textile waste with food waste improves methane yields, stabilizes digesters, and diverts waste from landfill. Optimal conditions include a high food waste share and a balanced C/N ratio.
A 74-year-old Chinese man presented with persistent nail separation, which led to the discovery of subungual amelanotic melanoma. The lesion was initially misdiagnosed, but histopathological evaluation revealed atypical melanocytes, prompting treatment and successful removal of the tumor.
Researchers developed a scalable photonic crystal scintillator that improves light extraction efficiency and X-ray imaging signal-to-noise ratio. The approach increased light output by 4.64-fold and maintained spatial resolution better than 25 μm.
Exosome/sEV therapy may support re-epithelialization in diabetic wounds through direct and indirect mechanisms. However, evidence linking exosome/sEV treatment to coordinated epithelial-mesenchymal plasticity-associated state transitions remains limited.
Recent progress in terahertz meta-device design is fueled by machine learning and deep learning approaches, promising improved performance and multifunctionality. However, challenges persist, including computational pressure, interpretability, and fabrication constraints.
Researchers discovered a molecular pendulum in hydrogenases, which captures protons for high catalytic activity. This mechanism is unique to Group A enzymes, suggesting evolutionary specialization.
The PROSPERO project seeks to overcome current telecommunications fragmentation by designing a unified framework for network and computing as a single logical resource. The goal is to achieve higher network reliability and reduce costs, enabling new business models and monetizable services.
A study has identified genetic clues to flowering time, salt stress responses, and seed characteristics in soybean landraces from Zhejiang Province, China. The researchers found 81 association signals across 11 agronomic traits and highlighted candidate genes that could guide future crop improvement.
Researchers from the Universities of Würzburg, Konstanz, and Tübingen are exploring Nadar's guest book, a 19th-century Parisian Golden Book. The team aims to reconstruct the cultural and historical context of the book, featuring entries from prominent figures like Charles Baudelaire and Gustave Doré.
The 2026 year class of juvenile striped bass maintains average abundance in Virginia waters, consistent with historically observed patterns. This represents a significant increase from 2024, with the population recovering from historic lows in the late 1970s and early 1980s.
Researchers have used X-rays to investigate the dynamics of quasiparticles in solids, revealing their interactions and potential for controlling electron spins. This could lead to the development of ultrafast logic components and more efficient electronics.
Researchers at ITQB NOVA are developing a portable sensor to measure phenylalanine levels for people with phenylketonuria (PKU), a rare metabolic disorder. The device aims to allow patients to adjust their diet and treatment in real-time, improving health outcomes and quality of life.
A new study found that mental health after trauma follows distinct patterns, predicting post-traumatic stress symptoms beyond distress levels. Early positive emotions and viewing the world as safe were associated with better outcomes, while empathy was linked to greater distress.
A new study by Penn State researchers found that pregnancy brain, or 'baby brain,' is associated with anxiety and depressive symptoms, but exercise may not be the solution. Women who exercised regularly may actually experience more brain fog if they have high levels of anxiety symptoms.
Scientists from the University of Surrey will develop an mRNA vaccine platform for major livestock species to tackle antimicrobial resistance and future epidemics. The platform aims to reduce reliance on antibiotics and improve resilience across farming systems.
A study by George Mason University researcher Kyeung Mi Oh found that caregivers' sleep, physical functioning, and emotional well-being are key factors associated with caregiving burden and psychological distress. The research highlights the importance of recognizing caregivers' health needs and providing tailored support to mitigate t...
Researchers mapped brain responses to faces and voices expressing different emotions, finding that emotional information is integrated across senses. The brain's response changes when processing faces and voices together, suggesting a combined emotional understanding.
This review systematically explores superhydrophobic wearable strain sensors' advances, addressing critical failure drawbacks and proposing reinforcement strategies. The authors establish a robustness optimization paradigm and comprehensive evaluation metrics to enhance environmental tolerance.
Researchers at the University of Jyväskylä have developed a new strategy for programming synthetic molecules to self-assemble into precise 3D structures. The approach, termed hierarchical sequence control, enables the formation of a triple helix with preferred handedness, surpassing current limitations in molecular organization.
A review of nine international studies found that 71% of caregivers experienced anxiety, 50% depression, and almost all struggled to care for themselves, while social isolation and poor sleep were common. Healthcare services can play a vital role in supporting caregivers by delivering coordinated care that includes them in follow-up care.
A new Flinders University paper highlights the benefits of rural medical education in strengthening healthcare access, building a sustainable workforce, and improving health outcomes in First Nations communities. The study emphasizes the importance of embedding First Nations knowledge and leadership in medical education, as well as rec...
A study at the University of Eastern Finland found that international students in Finnish universities face unmet expectations and conflicting pressures, leading to stress and frustration. The study highlights the need for career counseling to examine these conflicts and inequalities critically.
A new platform, SwiVirScan, has been developed to screen many antibody responses in parallel, revealing extensive viral exposure histories in pigs. The platform uses 36,416 short protein fragments from 140 swine-associated viruses to identify patterns of viral antibodies.
A single subcutaneous injection of a live, unattenuated influenza virus provides strong neutralizing antibodies and fully protects mice against a lethal challenge. The study decouples immunogenicity from pathogenicity by confining viral replication to the injection site.
Taylor & Francis has announced a new open access partnership with CRUI, the largest university association in Italy, supporting OA publishing of over 2,100 journals across various disciplines. The agreement enables researchers at CRUI-affiliated institutions to choose OA without paying a charge, with articles becoming OA immediately up...
A new study examines why recyclable waste moves between countries, how its price is formed and how public policy shapes these flows. The research finds that global trade in recyclable waste has remained at around 170–200 million tonnes per year since 2010, with high-income countries exporting up to 72 million tonnes more recyclable was...
A new framework identifies 13% of global land area as biodiversity hotspots, emphasizing the need for conservation approaches tailored to local conditions. The study considers multiple threats and proposes a method to update conservation priorities as new information becomes available.
A Johns Hopkins Medicine-led team will build an artificial intelligence model to identify protein misfolding for earlier disease detection and treatment. The goal is to generate tools and resources for clinicians and researchers to diagnose and intervene at earlier stages of neurodegenerative conditions.
A team at HZB reports polar vortices in BaTiO3/SrTiO3 superlattices on silicon, expanding materials and substrates options for complex ferroelectric states. The study opens up new possibilities for silicon-based technologies.
Researchers at the University of Illinois Chicago have developed a 4D biofabrication technology using kirigami strategies to generate complex tissue forms. This approach enables the creation of tissue geometries with precise control over shape and curvature, potentially addressing a longstanding challenge in tissue engineering.
Researchers found that GLP-1 receptor agonists were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease. This study suggests that a popular class of medications may offer an added benefit by helping protect kidney health in a high-risk group.
Breast cancer research is making progress through clinical trials, with 8 active trials currently open to patients and survivors. The trials aim to improve treatments and offer hope to millions of people affected by the disease.
The American Meteorological Society has selected three winners for its 2026 Photo Contest, with cash prizes ranging from $200 to $500. The contest, which received over 1,075 submissions from 84 countries, aims to capture themes of weather, water, and climate through original photography.
ViVac Pharma, an early-stage biotech company, develops RNA-based immunotherapies to reprogram the immune system to eradicate cancer. The company's platform mimics the immune-stimulating response of a natural viral infection, triggering a comprehensive attack to destroy cancer cells.
Researchers investigated the unique rolling behavior of dwarf reedsnakes, finding that they use alternating cycles of body rotation to maintain head stability. This sophisticated body control enables the snakes to overcome morphological constraints and achieve rapid, controlled locomotion at high speeds.
Researchers argue that the gut's enteric nervous system evolved first, influencing digestion and other essential functions, and may have driven the evolution of the brain. This reframing could lead to new avenues for research into conditions like obesity, diabetes, and Parkinson's disease.
Hantavirus infections can be spread through saliva, causing early oral warning signs such as severe sore throats and swelling of the face, neck, and throat. Dental teams should be aware of the risks and take precautions, including referring patients promptly and avoiding aerosol-generating equipment.
Researchers have successfully visualized the enzyme SacC, which plays a key role in building the complex core structure of the anti-sarcoma drug trabectedin. This achievement could lead to new approaches in optimizing existing compounds and creating new ones.
A new study found that partisan differences in perceptions of Covid-19 vaccine safety and effectiveness are more pronounced than those for MMR and flu vaccines. The study suggests that positive perceptions of science and scientists are more strongly associated with vaccine perceptions among Republicans than among Democrats.
A national study reveals that girls have been vaping at higher rates than boys in US adolescents since 2021, with the gap becoming more pronounced among older teenagers. The study suggests that vaping may be displacing cigarette smoking among young people, but researchers emphasize the need for public health action to address the alarm...
A study of 16 million participants found that ADHD is linked to higher rates of suicide, injury, and natural-cause mortality. However, taking ADHD medication appears to lower mortality risk, suggesting that medication may play a crucial role in supporting the health of people with ADHD.
A six-week home-based brain stimulation program combined with a video game showed promise in reducing depressive symptoms, but the experimental combination did not lead to greater improvement than a control condition. Both groups showed a marked reduction in depressive symptoms, raising questions about what drives symptom improvement i...
Frontiers will provide AI-powered data curation for 1,000 Horizon Europe datasets and award 100 FAIR Data Publication Grants to early-career researchers. This initiative aims to make research data easier to discover, understand, and reuse, supporting the European Strategy on AI in Science.
Researchers from the University of Osaka have uncovered the first steps in the development of ANCA-associated glomerulonephritis, a kidney disease triggered by ANCAs. They found that injured kidney cells send signals attracting immune cells, including neutrophils, which drive inflammation in the early stages.
A team at Kyushu University analyzed 1,623 annual securities reports from 340 Japanese food and beverage companies, finding that firms place greater emphasis on social issues, while environmental disclosure remains relatively limited. Disclosure priorities shifted after 2022, with greenhouse gas emissions showing the sharpest increase.
Dr. Steve Dellenback, VP of SwRI's Intelligent Systems Division, receives Lifetime Achievement Award for his work on intelligent transportation systems. He has developed and managed ITS software for the US public, deploying the ActiveITS platform across 15 state agencies.
FAU is developing post-quantum cryptographic protocols with advanced capabilities to secure digital communications and systems against future threats from quantum computers. The research will focus on algebraic structures and investigate protocols capable of supporting advanced cryptographic functions.
A new study by Klick Labs reveals complex patterns in voice recordings that are associated with Type 2 diabetes. The research used 14,759 voice recordings from 461 adults, analyzing spectrograms and identifying acoustic patterns related to diabetes. The study achieved balanced accuracy of 71.3 percent for women and 72.4 percent for men.
The European Space Agency's Euclid space telescope has made its first-ever discovery of a new comet, located approximately 1.3 billion kilometers away from Earth, using moving object detection software developed by Mikko Pöntinen. This groundbreaking finding demonstrates Euclid's capabilities in detecting fast-moving Solar System objec...
A new study finds that e-health literacy actively encourages young adults to visit doctors' offices, rather than relying on online health information for treatment. Higher e-health literacy was associated with more online research, doctor visits, and easier navigation of digital health platforms.
DS1025, a CD25-directed antibody drug conjugate, targets immunosuppressive regulatory T cells in the tumor microenvironment, aiming to reduce a mechanism that can limit the body's immune response against cancer. The trial is an international effort to investigate DS1025 in patients with advanced solid tumors.
Researchers discovered a protein called Miro1 linked to insulin resistance in muscle, offering a potential new target for future diabetes treatments. Removing Miro1 restored muscle response to insulin in preclinical models, while exercise reduced protein levels in people with Type 2 diabetes.
Researchers found that including small drainage channels up to a certain threshold improves flood simulations by reducing inundation depth and increasing river water levels. The study suggests using a minimum upstream drainage area (Amin) as a measure to determine how far upstream channels should be represented in flood models.
A new study reveals that accounting for daily weather variability leads to more realistic simulations of glacier melt, resulting in greater projected ice loss and sea-level rise. The study finds that short-term weather events, such as heatwaves and extreme melt seasons, play a significant role in glacier melting.
Researchers at Korea University developed an AI-guided strategy to discover potential antiviral compounds against viruses like HIV-1 and SARS-CoV-2. The study combined AI-guided molecular design with experimental validation to identify potential inhibitors of a host enzyme involved in viral replication.
Researchers have identified a new insect species on the Ogasawara Islands using genome-wide DNA data, revealing intricate evolutionary relationships among island insects. The study found that the Hahajima population is a distinct species, driven by geographic isolation and host plant shifts.
Researchers at UNIGE have discovered how cells prevent their repair system from rebuilding the cell wall during cell fusion, leading to an irreversible process. This mechanism, involving the enzyme Pak2, could lead to new antifungal strategies by disrupting cell wall formation and repair.
Researchers at ETH Zurich have developed a new, simpler approach to recycling acrylic glass polymers, achieving high monomer yields and pure material recovery. The process uses a single chemical reagent and requires lower energy than other methods, making it economically viable.
A new approach to education, known as the philosophy of pathos, recognizes passivity, suffering, and vulnerability as meaningful aspects of human life. This philosophy encourages a deeper engagement with experiences of suffering and makes space for complexity and contradictions.
A national poll found that four in five parents struggle financially to raise young children, with many supporting policies like paid leave, formula subsidies, and free childcare to alleviate these burdens. Parents are finding creative ways to make ends meet, but many want to help but are unsure where to start.
Research in Ontario found that 23% of people with de novo metastatic breast cancer died within 6 months of diagnosis, with factors including older age, chronic illness, and housing marginalization contributing to early death. Access to a primary care provider was associated with lower odds of early death and improved outcomes.