Researchers at National University of Singapore have identified a novel double-stranded DNA structure, dubbed S-DNA, which has sparked a 16-year scientific debate. The team's findings suggest that S-DNA may be a potential binding substrate for DNA intercalators and proteins.
A NUS-led team has discovered how bacteria respond to salt changes using specialized protein molecules that change shape in response to environmental salt concentrations. This finding provides a unified model of how bacteria sense their environment and has immediate applications in understanding life processes across species.
Researchers from NUS have discovered how a drug-lead compound named BPTES can deprive cancer cells of energy and stop them from growing into a tumour. Building on these findings, they also derived positive results for a novel dual-drug treatment regime that kills kidney and breast cancer cells more effectively.
Researchers at NUS identified a protein, FTIP1, that regulates flowering in plants under normal light conditions. Plants with mutant FTIP1 genes flowered later, but were restored to normal when the gene was functional.
A recent study found that Asian breast cancer patients suffer from memory loss, decision-making difficulties, and speech problems after chemotherapy treatment. To cope with these changes, many turned to mind stimulation activities such as mahjong and qi gong.
Researchers have discovered a way for soil bacteria to convert an epoxide into a six-membered cyclic ether, a common structural feature in hundreds of drug molecules. This breakthrough has implications for the development of new polyether drugs and potential biosynthesis strategies.
Researchers from National University of Singapore and Nanjing University establish a new scalar curvature flow method to solve the prescribing scalar curvature problem. The method adapts Hamilton's Ricci flow approach and infinitely dimensional Morse theory to tackle the problem, providing a stronger conclusion than previous methods.
Researchers developed a method to prevent graphene re-stacking and created materials that can process in solvents and film matrices, exhibiting giant broadband nonlinear optical absorption response. The discovery sets a new record in energy limiting onset of 10 mJ/cm^2 for linear transmittance of 70%.
Researchers at National University of Singapore discovered a collective electronic state not seen before in insulating oxides, exhibiting ferromagnetism. This is achieved through the interface of two materials, enabling novel electronic phases stabilized by the interface.
The Singapore research team led by Associate Professor Xiaogang Liu developed a synthesis of lanthanide-doped core-shell nanocrystals with advanced optical properties, enabling efficient upconversion and tunable light emission. This breakthrough has significant implications for cancer detection, medical imaging, and therapeutic delivery.
A recent study by the National University of Singapore reveals that climate change is causing a significant decrease in body size among various species worldwide. This trend has far-reaching implications for ecosystems and biodiversity, as smaller organisms can lead to reduced resource availability, population declines, and even loss o...
BioLynx Technologies Pte Ltd has launched a new biotech company to provide research tools targeting the international malaria research community. The company's LynxTag TM technology platform demonstrates biological activity similar to chloroquine, enabling researchers to visualize intracellular drug-cell interactions.
A comprehensive assessment of tropical forests found primary forests sustain the highest levels of biodiversity and are vital to many species. Human activities like logging and agricultural expansion have transformed most remaining primary forests, leaving little unaltered.
Researchers from National University of Singapore and Tsinghua University found that 88% of nature-derived drugs come from previously known drug-producing families. The study suggests focusing on these pre-existing families to discover new drugs, leveraging knowledge of clustered distribution patterns like oil fields.
At least 351 species thought to have disappeared over the past 122 years have been rediscovered, but most remain highly threatened and on the brink of extinction due to habitat loss. Researchers stress the need for rapid conservation efforts to prevent further decline.
Researchers at the National University of Singapore have invented a graphene-based polarizer that can broaden the bandwidth of prevailing optical fibre-based telecommunication systems. This innovation uses graphene to convert light beams into polarized light, enabling multiple-channel high-speed optical communications.