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Science News for September 6, 2011


Scientists make turfgrass safer for animals, deadly for insects

Researchers at Purdue University have created a type of turfgrass that is safe for grazing animals but toxic to certain insects. The fungus, called Neotyphodium, produces compounds that kill insects while protecting the grass from animal harm. This breakthrough could lead to reduced pesticide use and promote sustainability in agriculture.

SourcePurdue University·JournalJournal of Environmental Entomology·DateSep 6, 2011

Songs about sex – how they affect kids

Researchers analyzed Billboard Hot 100 song lyrics from 1959 to 2009, finding a significant increase in sexually explicit references over time. The study suggests degrading music can negatively impact teens' self-worth and lead to poor body image, depression, and substance abuse.

SourceSpringer·JournalSexuality & Culture·DateSep 6, 2011

Integrated health care delivery system and electronic health records support medication adherence

A Kaiser Permanente study found that patients in integrated healthcare systems with electronic health records and linked pharmacies are more likely to collect their new prescriptions for diabetes, cholesterol, and high blood pressure medications. The study revealed primary non-adherence rates of 7% for blood pressure medication, 11% fo...

SourceKaiser Permanente·JournalJournal of General Internal Medicine·DateSep 6, 2011

Chemotherapy can impair speech

Research from the University of Gothenburg found that chemotherapy can cause significant language difficulties in cancer patients, including trouble with sentence completion and word order. The study used a unique questionnaire to assess everyday life difficulties, resulting in an 80% response rate and a long follow-up period.

SourceUniversity of Gothenburg·JournalActa Oncologica·DateSep 6, 2011

Simulation an effective way to train health-care professionals

Mayo Clinic researchers analyzed over 600 studies on simulation-based training, finding it consistently better than no instruction for various learners and clinical topics. Simulation allows for practice without harming patients, repeated training to become more proficient, and structured learning for effective learning outcomes.

SourceMayo Clinic·JournalJAMA·DateSep 6, 2011

Metabolic state of brain cancer stem cells significantly different than the cancer cells they create

Researchers at UCLA found that brain cancer stem cells can change their metabolic state from glycolysis to oxidative phosphorylation, allowing them to evade treatment. This unique ability makes glioma stem cells resistant to conventional treatments, highlighting the need for new therapies targeting these cells specifically.

SourceUniversity of California - Los Angeles Health Sciences·JournalProceedings of the National Academy of Sciences·DateSep 6, 2011

Interventional radiologists: Learn about peripheral arterial disease and get moving

A recent study in the Journal of Vascular and Interventional Radiology found that exercise plays a crucial role in recovery from peripheral arterial disease after treatment. Interventions such as angioplasty and stenting can also help restore blood flow, improving walking ability and overall quality of life.

SourceSociety of Interventional Radiology·JournalJournal of Vascular and Interventional Radiology·DateSep 6, 2011

Misunderstanding surrounds HIV vaccine trials

A new University of Toronto study highlights the need for improved communication with high-risk communities about HIV vaccine trials. Researchers found that misinformation, distrust, and misunderstanding persist, affecting participants' willingness to participate.

SourceUniversity of Toronto·JournalAmerican Journal of Public Health·DateSep 6, 2011

The future of drugs is all in the family

Researchers from National University of Singapore and Tsinghua University found that 88% of nature-derived drugs come from previously known drug-producing families. The study suggests focusing on these pre-existing families to discover new drugs, leveraging knowledge of clustered distribution patterns like oil fields.

SourceNational University of Singapore·JournalProceedings of the National Academy of Sciences·DateSep 6, 2011

Financial consequences of illness devastating and understudied

A recent study argues that existing financial protection measures are insufficient and advocates for new indicators to identify those unable to afford healthcare. The findings highlight the need for improved measurement of financial protection in health systems to better support vulnerable populations.

SourcePLOS·JournalPLOS Medicine·DateSep 6, 2011

UCLA study shows loss of key estrogen regulator may lead to metabolic syndrome and atherosclerosis

A UCLA study reveals that the loss of a critical protein regulating estrogen and immune activity can lead to metabolic syndrome, characterized by Type 2 diabetes, atherosclerosis, and cancer. The research found that this protein's absence promotes increased fat accumulation, inflammation, and glucose intolerance in female mice.

SourceUniversity of California - Los Angeles Health Sciences·JournalProceedings of the National Academy of Sciences·DateSep 6, 2011

Lifetime 'dose' of excess weight linked to risk of diabetes, according to U-M study

A new University of Michigan Health System study found that the degree and duration of obesity in adolescents and young adults significantly increase the risk of developing type 2 diabetes. The study also revealed that black and Hispanic individuals are more susceptible to diabetes for a given amount of excess weight over time.

SourceMichigan Medicine - University of Michigan·JournalArchives of Pediatrics and Adolescent Medicine·DateSep 6, 2011

Ultrasound improves stem cell transplants

Researchers from Lund University have developed a method using ultrasound to improve the quality of transplanted blood stem cells. This improvement could lead to better treatment outcomes and reduced risk of graft-versus-host disease and infections.

SourceLund University·JournalPLOS ONE·DateSep 6, 2011

A 'jumping gene's' preferred targets may influence genome evolution

Researchers have discovered that certain transposon elements can coordinate their movement with DNA replication, allowing them to spread more rapidly through genomes. P elements, one such transposon, tend to insert themselves near the beginning of genes and at regions functioning as starting sites or origins for DNA duplication.

SourceCarnegie Institution for Science·JournalProceedings of the National Academy of Sciences·DateSep 6, 2011

Virtual reality may help adults recover from stroke

Early results suggest that virtual reality (VR) human-computer interfaces can improve arm function and daily activities in adult stroke patients compared to traditional therapy. VR training has been found to have positive effects on these outcomes, but more data is needed to assess the long-lasting benefits of this approach.

SourceWiley·JournalCochrane Database of Systematic Reviews·DateSep 6, 2011

Researchers identify new drug target that stimulates

JDRF-funded researchers identify a protein and chemical compound that stimulate beta cell growth, providing a new drug target for diabetes treatment. The discovery may lead to the development of tests to measure beta cell number using Tmem27 fragments as a biomarker.

SourceJDRF·JournalCell Metabolism·DateSep 6, 2011

Pain relief can now be based on solid evidence

A Cochrane Review analyzed 35 Cochrane Reviews of randomized trials to evaluate the effectiveness of 46 different drug/dose combinations against acute pain. The review found that no single drug provides high levels of pain relief for all patients, but some options have a solid evidence base

SourceWiley·JournalCochrane Database of Systematic Reviews·DateSep 6, 2011

Recycling fat might help worms live longer

Researchers found that increased autophagy in germline-less worms led to higher activity of a fat-digesting enzyme, extending their lifespan. The study suggests that recycling fat is beneficial for worms, and may have implications for human diseases such as cancer and Alzheimer's.

SourceSanford Burnham Prebys·JournalCurrent Biology·DateSep 6, 2011

Prenatal exposure to phthalates linked to decreased mental and motor development

A new study found that prenatal exposure to phthalates is associated with decreased mental and motor development in preschoolers, as well as increased behavioral problems. The researchers measured metabolites of four phthalates in maternal urine and evaluated associations between prenatal exposures and child development at age 3.

SourceColumbia University's Mailman School of Public Health·JournalEnvironmental Health Perspectives·DateSep 6, 2011

Circadian clocks in a blind fish

Researchers found that a species of cavefish, Phreatichthys andruzzii, has an unusual circadian clock that ticks at an extremely long period, unaffected by eye loss. The study suggests that the fish's clocks can be regulated by feeding behaviour, but not light exposure.

SourcePLOS·JournalPLOS Biology·DateSep 6, 2011

Violence remains in top 10 causes of death

The National Center for Injury Prevention and Control and the American Journal of Lifestyle Medicine have developed a special issue to examine violence prevention. The issue highlights the complexities of violence and its deep impact on society, with significant monetary effects estimated at over $70 billion annually.

SourceSAGE·JournalAmerican Journal of Lifestyle Medicine·DateSep 6, 2011

Major advance in sleeping sickness drug made by Glasgow scientists

Researchers at the University of Glasgow have created a safer oral version of the sleeping sickness drug melarsoprol, increasing its solubility and releasing it slowly in the gut. The new treatment retained its ability to kill the infection and cured mice infected with the parasite after a seven-day daily dosing schedule.

SourcePLOS·JournalPLOS Neglected Tropical Diseases·DateSep 6, 2011

'White-coat effect' elevates greyhounds' blood pressure

A new study has found that retired racing greyhounds' blood pressure increases significantly when taken to a veterinary clinic, but returns to normal at home. The 'white-coat effect' was observed in 22 greyhounds, with systolic pressures averaging 30 points higher in the hospital than at home.

SourceOhio State University·JournalJournal of Veterinary Internal Medicine·DateSep 6, 2011