A new study presents a tumour-customizable mRNA nanomedicine platform that demonstrated efficient mRNA delivery to cancer cells while minimizing harm to healthy tissues. The platform elicited a strong immune response, effectively turning
Scientists at UC Davis have discovered a new species of trapdoor spider, Aptostichus ramirezae, in California's coastal sand dunes. The study reveals that what was thought to be one species is actually two, highlighting the need for conservation efforts to protect habitats shrinking due to climate change and human development.
Researchers have identified a new genetic marker, HLA-A*34:02, which can predict severe gout drug reactions in US patients when combined with HLA-B*58:01. This discovery could improve the safety of allopurinol for millions by expanding genetic screening.
POEM offers excellent dysphagia relief in complex cases, while LHM is preferred for patients with hiatal hernias or concerns about PPI use. POEM excels in type III achalasia and redo procedures, while LHM remains the option for patients with reflux risk.
Researchers achieved first superconductivity in nickel-based superconductors in 2019, with critical temperatures reaching up to 80 K in bilayer La₃Ni₂O₇ under high pressure. Recent breakthroughs enable superconductivity at ambient pressure via strain engineering.
The US economy is expected to grow at 1.8% in 2026, with AI and energy infrastructure investments playing a key role. Despite this, job creation will not be strong enough to keep unemployment rates from rising to 4.8%, with the nation's economy facing uncertainty around trade policy.
A new treatment using platelet-rich plasma (PRP) injections has shown promising results in helping people recover their sense of smell after head injuries. Two-thirds of patients reported improvements in their ability to smell, with significant objective improvements measured at three months.
Solid polymer electrolytes offer a safer alternative to traditional liquid electrolytes, with intrinsic adhesion to electrodes and low interfacial resistance. The authors propose multi-pronged innovations to improve contact, reduce polarization, and prevent dendrites.
A new study finds that gradual land subsidence poses a growing threat to buildings across India's largest cities. Over 2,400 structures in New Delhi, Mumbai, and Chennai are already at high risk of damage, while up to 23,529 buildings could face very high risk if current trends continue for the next 50 years.
Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.
The study maps the entire genetic diversity of oats, including genes present in different species and tissues. The research found that certain genes have been lost but others take over their functions, suggesting a complex genetic landscape.
Researchers found that AI models predict protein structures despite modifications in amino acid sequences or ligands, indicating a lack of understanding of physical chemistry. The models only recognize patterns they've seen before and struggle with unknown proteins.
Researchers identified three types of online brand defenders: promoters (emotionally attached), justice promoters (fairness driven), and self-promoters (ego-driven). Companies can encourage promoters by acknowledging them, while justice promoters require a sense of fairness. Self-promoters are motivated by attention and rewards.
Researchers found that traditional protocols isolate platelet contaminants, whereas optimized protocol yields uniform, cell-derived microvesicles. These findings redefine long-standing assumptions and establish a new foundation for accurately interpreting microvesicle functions.
Researchers have captured a key part of the ribosome formation process, revealing how cells coordinate, regulate, and safeguard protein factory creation. The 'molecular movie' shows the role of Mtr4 enzyme and Utp14 protein in assembly, as well as an elaborate system of built-in safeguards.
A novel digital health program, WECARE 2.0, has been shown to enhance the physical and mental well-being of Chinese American dementia caregivers. Participants reported improved caregiving skills, reduced stress, and increased social support through user-friendly culturally-tailored interventions.
Researchers have mapped the full genetic diversity of oat lines to understand their capacity for adaptation and resilience. The study provides a comprehensive overview of the pan-genome, including a directory of gene activity across different tissues and lines.
The European Society of Endocrinology (ESE) has announced the winners of the 2026 ESE Awards, which recognize outstanding contributions to improving knowledge and expertise in endocrinology. This year's winners include Martin Reincke for his work on neuroendocrinology and Maria-Christina Zennaro for her research on hypertension.
Researchers have developed a menstrual cup with a plant-based, absorbent coating that repels bacteria and requires minimal cleaning. The coating and absorbent tablet could reduce the time and effort needed to clean and maintain menstrual cups, making them more accessible and equitable globally.
A new report warns that the planet is on a dangerous path and that rapid action can avert the worst outcomes of climate change. The report highlights the need for effective climate mitigation and adaptation strategies, including reducing fossil fuel consumption and promoting renewable energy sources.
A new kind of electrochemical system combines two chemical reactions, oxidation and hydrogenation, to produce renewable plastics and fine chemicals. The process achieves full conversion of plant-based molecules into the desired products with high efficiency and stability.
Researchers developed a machine learning-based workflow, SPaDe-CSP, to predict crystal structures of organic molecules. The workflow narrows the search space by predicting probable space groups and crystal densities before computationally intensive relaxation steps.
Nagur Shareef Shaik's AI-powered data intelligence platform PRISM automates data workflows through automation, transparency and ethical AI integration. It empowers users to get critical insights from their data securely and instantly without needing programming expertise.
Research highlights the challenges of maintaining fat bike trails due to climate disruption and volunteer burnout. The study calls for seasonal strategies to distribute workload, create binational events, and implement recognition programs.
The National TRAP Program has awarded $1.8M to 13 projects focused on removing derelict fishing gear from US coastal waters, resulting in the removal of over 7,000 traps and 300,000 pounds of debris. The program aims to improve derelict trap prevention and mitigation through data analysis and policy recommendations.
A new report published in BioScience reveals Earth's climate crisis is accelerating at an alarming rate, with 22 of 34 planetary vital signs now at record levels. The study emphasizes that climate change mitigation strategies are available and urgently needed to limit warming.
Researchers found that female astronauts showed a greater reduction in brain fluid shifts than their male counterparts. Globe flattening, a form of eye compression, was the most consistent eye change among crew members, with males experiencing more frequent changes.
Researchers developed a vertical drawing technique to fabricate intricate micro/nano optical fibers with tailored geometric precision. The approach enables meticulous control over diameter transitions and unlocks new possibilities for manipulating light-matter interactions, including supercontinuum generation.
The University of Phoenix College of Doctoral Studies has released a white paper on mentorship programs that can help organizations address the growing crisis of worker autonomy. The study highlights the importance of skills-focused development, such as mentorship, to reduce burnout and improve retention.
Researchers uncovered the oldest known complex three-dimensional burrow systems in Hubei's Shibantan Biota, dating back approximately 550 million years. These trace fossils show that complex animal behaviors emerged nearly 10 million years earlier than previously thought.
The study highlights the frequent use of aerosol therapy in critically ill patients with acute respiratory distress syndrome (ARDS), with bronchodilators being the most commonly prescribed drugs. However, the lack of sound scientific evidence and randomized controlled trials suggests that standardized protocols are needed to align clin...
A new study reveals the deep connection between wildlife trafficking and other serious crimes, including arms dealing and human smuggling. By mapping these intersections, researchers can focus on key players driving global networks, boosting anti-trafficking interventions.
Dr. Anna Wuttig, a UChicago chemist, receives the award for her innovative work on electrocatalysis for energy storage and conversion, as well as medicinal chemistry. Her lab develops new concepts that integrate physical and synthetic inorganic and organic chemistry to enhance catalytic reactions.
A Rutgers University review of 31 studies found that exposure to digital alcohol marketing increases the likelihood of past 30-day alcohol use, binge drinking, and susceptibility to drinking. The study suggests that algorithmic amplification can normalize alcohol for subsets of young people, leading to increased drinking behaviors.
Researchers developed an ultrasonic microrobot capable of ultrafast bidirectional navigation in confined tubular environments. The robot achieves high speed and low voltage operation, while maintaining stability in various environments and carrying loads beyond its weight.
A study published in PLOS One mapped ancient tomb distributions across China to identify patterns influenced by socioeconomic factors and geography. The research found that tombs from periods of relative stability were more common than those during times of war and instability.
Researchers at the University of Freiburg are developing boronic acid-catalysed amidation reactions that use sustainable solvents, consume little energy, and produce only water as a by-product. The AI-powered approach aims to improve resource efficiency in the chemical industry and achieve United Nations' global sustainability goals.
An international team is calling for a US $14 billion investment to protect and restore one million hectares of kelp forests by 2040. The funding would help achieve the Kelp Forest Challenge, a global mission to conserve and restore three million hectares of kelp forests, which fringe nearly a third of the world's coastlines.
A study published in Neurology found that veterans with epilepsy after a traumatic brain injury had a higher mortality rate compared to those with no prior traumatic brain injury. The risk varied by cause of the traumatic brain injury, with those with skull or facial fractures having an 18% higher risk of death.
A new Oxford-led study reveals Africa's wildlife ecosystems are running on less than two-thirds of their natural energy, posing risks to biodiversity and the livelihoods that depend on it. The research uses an ecosystem energetics approach to quantify how energy flows through food webs, finding that smaller species now dominate Africa'...
Researchers have developed 3D-printable super-black silica-carbon composite aerogels with unmatched multifunctionality. These aerogels combine ultra-low thermal conductivity and extreme light absorption for transformative potential in thermal insulation and solar-driven applications.
Pennington Biomedical researchers will participate in numerous panels and presentations during the conference, sharing their latest findings on obesity treatment and prevention. The institution is well-represented at the event, with faculty members among the experts leading courses, presentations, and speaker panels.
The People's Case for Curators highlights the vital role of information curators in navigating today's complex landscape. The guide emphasizes their importance in uncovering and sharing reliable scientific information.
Researchers created an artificial tongue using milk powder that can detect capsaicin and pungent-flavored compounds, including those found in hot sauces. The study's findings show the potential of the casein-containing material to quickly test a food's spiciness level without putting taste buds at risk.
Dr. Jonathan D. Licht, a renowned expert in blood cancer and epigenetics, will succeed Peter A. Jones as the next president and chief scientific officer of Van Andel Institute. Licht's extensive research experience and leadership skills will further strengthen the Institute's efforts to improve health and lives.
The RADAR pathway is a specialized quality control mechanism in yeast peroxisomes that prevents malfunctions and supports cellular health. It involves the AAA-ATPase Cdc48p, which extracts defective import receptors from the peroxisomal membrane for degradation by the proteasome.
A recent study found that over 11,000 physicians were sponsored for H-1B visas in the US, representing 1% of the workforce. Notably, rural counties had nearly twice the percentage of H-1B-sponsored physicians compared to urban areas.
A recent presidential proclamation increased H1-B visa fees, affecting international doctors sponsored by the program. Rural and high-poverty counties will likely face significant challenges in accessing healthcare services due to a shortage of foreign healthcare workers.
Researchers examine how genAI affects task structure, worker adoption, and job displacement. The authors suggest genAI will widen the 'cone of automation,' substituting for complex work and infrequent tasks.
This study finds that PCB congeners accumulate in intermediate waters of the Sea of Japan due to air-sea exchange, bio-particle sorption, and remineralization. The biological pump enhances the subsurface delivery of PCBs, which poses risks to mid-water and benthopelagic biota.
A study by Wake Forest University School of Medicine reveals that a stress response in immune cells contributes to chemotherapy-induced nerve damage. By blocking this pathway, researchers aim to develop new treatments to protect cancer patients from debilitating side effects.
Researchers found significant overlap in ultrarare genetic variants between ALS and HSP, including newly identified genes contributing to disease risk for both conditions. This study highlights the shared origins of these disorders and may lead to more personalized care for patients.
A new study by Tel Aviv University researchers challenges the common belief that tipping is a key motivator for better service. The study reveals that tipping rates are driven more by social pressure than genuine appreciation for the service. As a result, average tipping rates tend to rise over time in societies with stronger norms.
Researchers at University of California San Diego School of Medicine have harnessed bioinformatics to identify Thiorphan as a promising new drug for spinal cord injury, showing effectiveness in adult human brain cells and improving hand function in rats with SCI.
Scientists from Salk and UC San Diego have discovered a new hybrid seagrass that demonstrates low-light tolerance, offering a promising solution for coastal restoration efforts. The hybrid combines the shallow-water Zostera marina with its deeper-water cousin Zostera pacifica, inheriting the latter's low-light toolkit.
Kobe University's new web application combines quantum game theory with jazz improvisation to explore creativity. Users can interact in a 'quantum jam session', receiving real-time visual and auditory feedback on their strategies.
Dr. Bruce D. Gelb, MD, is selected as recipient of the 2026 APS John Howland Award for his groundbreaking work on congenital heart disease (CHD) and related developmental disorders. His research has significantly expanded the scientific understanding of CHD and opened new avenues for diagnostic approaches.
Researchers discovered a unique protein in bowhead whales that repairs damaged DNA, potentially contributing to their remarkable longevity. The protein, CIRBP, is present at 100-fold higher levels in bowhead whales compared to other mammals.
Researchers develop serial tissue optical clearing methods to image neuro-vasculature of whole organ in mouse, enabling study of larger animal models like pigs and non-human primates. The technique facilitates the study of organ development and disease mechanisms in models closer to humans.
Researchers found that combining serum neurofilament light chain (sNfL) and cardiac troponin T (cTnT) biomarkers significantly improves ALS diagnosis by differentiating it from other neurodegenerative diseases. The study identified an ALS-specific threshold for cTnT, allowing for increased sensitivity in identifying affected patients.