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National University of Singapore


New S$130 million national research initiative to enhance Singapore’s strategic research capabilities in RNA biology and its applications

The National Initiative for RNA Biology and Its Applications (NIRBA) aims to strengthen Singapore's RNA research capabilities, focusing on human health and diverse applications. The program will integrate leading institutions and promote interdisciplinary collaborations to achieve groundbreaking scientific discoveries.

NUS scientists develop realistic ‘micro-gut’ model to study the relationship between gut microbes and human diseases

Researchers developed a 3D microscopic version of the human intestines on a chip, allowing for real-time examination of gut microbes' interactions with the human intestine. The 'Gut-Microbiome on a chip' model enables the study of complex interplay between gut microbes and health, facilitating targeted microbiome-based interventions.

SourceNational University of Singapore·JournalAdvanced Science·TypeExperimental study·DateFeb 9, 2025

NUS researchers pioneer DNA-tagged gold nanoparticles for targeted cancer treatment

The team's novel technique enables high-throughput screening of nanoparticle shapes, sizes, and modifications, reducing associated screening costs. The research demonstrates the distinct preferences of tumour cells for certain nanoparticle configurations, enabling personalized cancer treatments that are safer and more effective.

SourceNational University of Singapore·JournalAdvanced Functional Materials·TypeExperimental study·DateJan 27, 2025

Singapore ranks 10th globally in readiness for a rapidly ageing society: Study by NUS and Columbia University

A recent study by NUS and Columbia University ranked Singapore among the top 10 nations globally for its readiness to address the challenges of an ageing population. The study found that Singapore performed well in key domains such as well-being, security, and equity, with strengths in healthcare systems and social cohesion.

SourceNational University of Singapore·JournalNature Aging·DateDec 27, 2024

Uncovering Salmonella dry surface biofilm

Researchers have discovered unique features of Salmonella dry surface biofilms, including a dense capsule and 'sandwich-like' structure, which contribute to their antimicrobial resistance. The study also identified potential safety concerns and developed an effective water-free antibiofilm strategy for the food industry.

SourceNational University of Singapore·JournalApplied and Environmental Microbiology·TypeObservational study·DateDec 15, 2024

NUS and A*STAR researchers discover cell-type-specific link between alternative splicing and autoimmune disease inheritance

Researchers from NUS and A*STAR have discovered a connection between the regulation of alternative splicing in different cell types and the predisposition to autoimmune diseases. The study used a population-scale single-cell gene expression profiling dataset to analyze splicing events specific to particular cell types, revealing ancest...

SourceNational University of Singapore·JournalNature Genetics·DateDec 3, 2024

Unique multidomain enzymes from bacteria

Researchers have identified a unique multidomain enzyme capable of catalysing two separate reactions, cyclization and hydroxylation, on a single peptide substrate. This breakthrough discovery opens the possibility of developing innovative drug molecules with potential therapeutic applications for life-threatening infections and cancer.

SourceNational University of Singapore·JournalNature Chemistry·DateOct 28, 2024

NUS and A*STAR researchers develop wearable, stretchable sensor for quick, continuous, and non-invasive detection of solid-state skin biomarkers

Scientists created a wearable sensor that can monitor cholesterol and lactate levels on dry skin, enabling early disease detection. The sensor overcomes existing challenges of traditional methods, promising new opportunities for remote patient monitoring and population-wide health screening.

SourceNational University of Singapore·JournalNature Materials·TypeExperimental study·DateAug 19, 2024

NUS researchers develop a novel technique to fabricate three-dimensional circuits for advanced electronics

The NUS researchers developed a state-of-the-art technique called CHARM3D to fabricate three-dimensional electronic circuits with high electrical conductivity, self-healing capabilities, and recyclability. This new technique enables the printing of free-standing metallic structures without support materials or external pressure.

SourceNational University of Singapore·JournalNature Electronics·DateJul 29, 2024

NUS researchers develop new battery-free technology to power electronic devices using ambient radiofrequency signals

A team of NUS researchers developed a compact and sensitive rectifier technology that uses nanoscale spin-rectifiers to convert ambient wireless radio frequency signals into DC voltage. The technology overcomes challenges in existing energy harvesting modules, enabling battery-free operation for small electronic devices.

SourceNational University of Singapore·JournalNature Electronics·TypeExperimental study·DateJul 24, 2024

Boosting the synthesis of stable sugar compounds with a novel nature-inspired approach

Researchers have developed a novel approach to convert native sugars into diverse classes of stable glycosides and glycoproteins. This biomimetic concept uses 'cap and glycosylate' technology to selectively activate and substitute the anomeric hydroxyl group in a native sugar, generating a temporary thioglycoside intermediate that unde...

SourceNational University of Singapore·JournalNature·TypeExperimental study·DateJun 19, 2024