Researchers found that freshwater fish populations near the poles are outperforming their equatorial counterparts due to warming temperatures. Species with larger body sizes and higher trophic levels are responding positively to climate change.
The UN reports that over 77.6% of the world's land experienced drier conditions in recent decades, with drylands expanding by nearly a third larger than India. This trend is driven by human-caused climate change and has dire implications for agriculture, ecosystems, and people living in affected areas.
Researchers have redefined the mechanisms of OER and Ir dissolution in highly dimensional amorphous hydrous iridium oxides. A novel surface H-terminated nanosheet model reveals elongated Ir-O bond lengths and thermodynamically driven Ir dissolution, challenging traditional understanding.
A new study has identified two distinct subtypes of metabolic dysfunction-associated steatotic liver disease (MASH) with similar histological features but different clinical outcomes. The research empowers clinicians to adopt subtype-specific treatments leveraging simple clinical markers, offering a clear path to improve patient outcomes.
The 47th San Antonio Breast Cancer Symposium is the world's largest breast cancer research conference, attracting over 11,000 attendees from 102 countries. The event showcases groundbreaking discoveries in drug development and advances care for underserved populations.
E-scooter and e-bike injuries in the US have tripled since 2019, with most incidents involving alcohol or substance use, particularly among young riders. The study found that nearly 18% of e-scooter visits and 12.5% of e-bike visits ended in hospital admissions.
A team proposes an adaptive robust optimization approach to minimize operating costs in hybrid hydrogen-battery energy storage systems within microgrids. The approach integrates SoC management and considers uncertainty from a holistic daily perspective, affirming exceptional performance efficiency and resilience.
The study presents strong overall responses with a triplet regimen including a novel menin inhibitor, achieving an 82% overall response rate in relapsed or refractory acute myeloid leukemia patients. The combination also demonstrated manageable side effects and significant clinical benefits, providing patients with improved treatment o...
Dr. Christopher Seet has received a $2.9 million R37 MERIT Award from the National Cancer Institute to develop innovative T cell therapies for cancer. The grant will support research into iPSC-derived T cells, which can be engineered for enhanced tumor-fighting capabilities.
Researchers from Case Western Reserve University discovered a large cavern in Manot Cave that was used as a gathering space for rituals, possibly enhancing social cohesion. The site features an engraved rock with a turtle-shell design, contemporaneous with some of the oldest cave paintings in France.
A study published in JAMA found that biomarker-guided antibiotic duration reduced in hospitalized patients with suspected sepsis. However, a daily C-reactive protein-guided protocol did not demonstrate significant benefits. The results suggest that procalcitonin-guided protocols may be a more effective approach.
A study by Indiana University School of Medicine researchers reveals that Toxoplasma gondii parasites use cap-independent translation to make proteins for dormant stages, evading drug treatment. This unconventional method has been found in both the parasite and human cells, making it a potential target for new treatments.
Scripps Research scientists created an AI model called MovieNet that processes videos by mirroring brain processes, recognizing visual scenes and distinguishing subtle changes. This breakthrough has the potential to transform fields like medical diagnostics, autonomous driving and more.
Researchers at Johns Hopkins Medicine have discovered that excessive Gata4 protein accumulation in vascular smooth muscle cells contributes to aortic aneurysm vulnerability in Loeys-Dietz patients. The study's findings may help refine treatments for this genetic disorder, which affects connective tissue systems.
Researchers at USTC have developed a novel photocatalyst that can efficiently degrade 'Forever chemicals' at low temperatures. The method involves the use of a super-photoreductant, KQGZ, which can promote complete defluorination and mineralization of Teflon and small molecule PFASs.
A new study found that Norwegian boys are outperforming girls in learning English as a second language, with the gap increasing at age 13. The researchers suggest that online gaming and digital technology may be contributing factors, contradicting conventional wisdom about gender differences in language acquisition.
Patients with lower education levels and income are less likely to receive stem cell transplants, but accessing treatment equalizes benefits. The study found socioeconomic factors have a less pronounced impact on post-transplant outcomes.
A new toolkit has been developed for clinicians involved in Child Death Review to improve support for bereaved parents. The recommendations include having a named bereavement support key worker within 24-48 hours after the child's death and providing training for healthcare professionals to better understand parents' roles.
Researchers have designed a new strategy for creating pure-red organic light emitting diodes (OLEDs) with improved efficiency and color purity. The molecule BNTPA achieves record-breaking external quantum efficiency, making it suitable for next-generation high-definition displays and energy-efficient lighting systems.
Researchers at City University of Hong Kong have observed a new vortex electric field with the potential to enhance electronic, magnetic and optical devices. The discovery enables the creation of quasicrystals with versatile applications in memory stability, computing speed, spintronics and sensing devices.
A phase 3 trial found that combining a second-generation BTK inhibitor, acalabrutinib, with a BCL-2 inhibitor, venetoclax, resulted in high progression-free survival rates and low toxicity. The treatment showed promise in treating chronic lymphocytic leukemia (CLL) patients.
Okayama University of Science has ranked 601+ globally and tied for 22nd among Japanese universities in the Interdisciplinary Science Rankings. The university excelled in the process category, ranking 15th in Japan, due to its high-quality research facilities and strong institutional support.
Researchers from USTC and Harvard Medical School create PocketGen, a deep generative model for generating protein pocket sequences and spatial structures. The model achieves over 10-fold improvement in speed and demonstrates high accuracy in binding small molecules.
A recent study by Duke-NUS Medical School has discovered that foetuses possess a functional immune system capable of combating infections before birth. This breakthrough finding suggests that fetuses are not defenceless against diseases and infections like Zika, which can cause serious health conditions such as microcephaly.
Two clinical trials testing loncastuximab tesirine showed promising results in patients with high-risk forms of follicular lymphoma and marginal zone lymphoma. The treatment achieved impressive response rates, including a 70% complete response rate for marginal zone lymphoma and an overall response rate of 97% for follicular lymphoma.
Researchers reconstructed the energy spectrum of a significant SEP event on February 15, 2022, for Mars using data from multiple detectors and models. This breakthrough enhances understanding of the Martian radiation environment, crucial for future mission safety.
Scientists have discovered proton halos in several exotic atomic nuclei, including phosphorus-26 and sulfur-27, using precise nuclear masses. The findings shed light on potential experimental and theoretical research on proton halo nuclei.
Researchers have developed a novel imaging device called Nonlocal-Cam that extracts additional spectral and polarization information, empowering new applications in machine vision and microscopy. The camera leverages nonlocal dispersion in optically active materials to capture hidden data.
The new guidelines provide 145 recommendations on symptoms, diagnosis, causation, sequelae, and treatment of POI. They emphasize personalized hormone therapy, prompt institution, and continuation until the usual age of menopause to prevent chronic disease and improve patient outcomes.
A new study by Reichman University reveals a digital treatment protocol improving spatial memory tasks and brain connectivity in aging adults. The innovative mobile app harnesses neuroplasticity to enhance navigational knowledge and potentially mitigate age-related cognitive decline.
New research from Flinders University suggests the Zuytdorp shipwreck was caused by a storm, not poor navigation. The authors analyzed historical records and weather patterns to support their findings.
A new study published in the journal Nutres found that adopting a healthy diet can reduce the severity of chronic pain, regardless of body weight. The research, conducted by the University of South Australia, explored associations between body fat, diet, and pain and found that higher consumption of core foods was directly associated w...
Branden Baptiste, 20, becomes the world's first patient to receive base editing gene therapy for sickle cell disease. The treatment has left him feeling 'more than fine' with no symptoms of the disease. After undergoing chemotherapy and a series of tests, Branden was infused with genetically treated cells in December 2023, allowing his...
Researchers at Memorial Sloan Kettering Cancer Center found that a high fiber plant-based dietary intervention can significantly improve disease progression trajectory in participants with precancerous blood disorder. After 12 weeks, two participants showed a significant improvement and none progressed to multiple myeloma within one year.
Researchers from Tokyo Metropolitan University found that agricultural land preserved around river confluences can reduce flood risks, with stronger correlation near confluence points. This Eco-DRR approach uses existing environmental resources to improve resilience against flooding.
A global clinical trial has shown a significant improvement in disease-free survival rates for children with B-cell acute lymphoblastic leukemia (B-ALL) by combining standard chemotherapy with blinatumomab, an immunotherapy. The study found improved survival rates of up to 97.5% after three years, compared to 90% with chemotherapy alone.
Researchers found that a ketogenic diet's beta-hydroxybutyrate (BHB) improves tumor control and survival in mice with diffuse-large B-cell lymphoma. A BHB supplement also boosts CAR T cell expansion and activation in laboratory models of human cancer.
A new simulator study demonstrates the role of the nasal cavity in dispersing respiratory aerosols, impacting disease transmission. Aerosol dynamics vary depending on exhalation method and environment.
A new grant will support a five-year investigation into the role of the brain's reward network in two neurodevelopmental conditions. Researchers will use high-resolution fMRI scans to analyze how the reward network interacts with other parts of the brain in autism, ADHD, and co-occurring autism and ADHD.
Researchers have developed a network-based approach to understand how immune cells called microglia transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study identified three unique subtypes of harmful microglia that promote disease progression, with genetic signatures driving their behaviors.
A study led by UF Health Cancer Center researchers found that a toxin in the bacteria Campylobacter jejuni accelerates the spread of colorectal tumors. The findings could lead to new tools for detecting metastatic colorectal cancer early, ultimately helping determine patients who need more aggressive treatments.
The University of Tennessee Institute of Agriculture has won a four-year grant to create hands-on curriculum about AI-related technologies for future farmers and leaders. Selected students will test the curriculum in drones, robotics, and other smart agriculture technologies, gaining skills in coding, drone-work, and robotics.
Researchers found that roof greening in all major Chinese cities could potentially create a large carbon sink, with grass planting scenarios showing approximately 52.2 Tg C a−1 emissions offset, equivalent to fully offsetting household emissions. Prioritizing greenery on low-rise roofs can harvest the most carbon sinks, over 90%.
The study found that critical states in animal groups consist of heterogeneous structures, with role sharing among individuals being crucial for optimized decision-making. The distribution of criticality was nonuniform within the group, but averaging confirmed traditional criticality status.
Researchers discovered a single mutation in the H5N1 virus that improves its ability to attach to human cells, potentially making it easier for humans to become infected. The study's findings stress the importance of continued genomic surveillance and public health preparedness to monitor potential genetic changes.
A study reveals that 36 non-native mammal species are threatened in their original range, highlighting the need to weigh opportunities and risks of non-native populations for species survival
Researchers at Wake Forest University School of Medicine found a strong association between living in disadvantaged neighborhoods and higher blood pressure and lower cognitive scores. The study analyzed data from over 500 adults aged 55+ and used the Area Deprivation Index to measure neighborhood disadvantage.
The University of Virginia School of Data Science will receive a $20 million grant from the Quantitative Foundation to support the construction of a new building. The facility will enhance the school's research, scholarship, and teaching capabilities, while fostering an entrepreneurial ecosystem.
The EPFL researchers built a drone with birdlike legs that can walk, hop, and jump into flight, greatly expanding the potential environments for unmanned aerial vehicles. The design allows it to take off autonomously in previously inaccessible environments.
KIST researchers develop a nanostructured composite fiber material to efficiently recover rare earth metals from waste permanent magnets and industrial wastewaters. The material achieves high adsorption capacities, outperforming conventional adsorption materials.
A hybrid method links bottom-up behaviors and top-down causation in a single theory to capture interactions between small-scale behaviors and system-level properties in disturbed systems. The approach has been tested in examples such as post-fire forest ecosystems and pandemics, predicting ecological patterns and system dynamics.
Researchers from Linköping University confirmed a direct connection between quantum theory and information theory, revealing the degree of unknown information in a quantum system. The study used a new experimental setup to demonstrate the equivalence of entropic uncertainty with wave-particle duality.
Scientists at The Jackson Laboratory have identified the CAST/EiJ mouse as a highly susceptible model for studying severe COVID-19. This genetically pure background allows researchers to investigate the virus's impact without artificial receptor modifications, mirroring human responses. Initial trials using antiviral treatments show pr...
Research reveals two unique mercury accumulation patterns in Qinghai-Tibet Plateau wetlands, driven by climate change and human impact. The study found a 'Surface Peak' in monsoon-controlled regions and a 'Subsurface Peak' in westerly-controlled regions, highlighting the need for ecological sustainability efforts.
Researchers discovered that BKPyV's large tumor antigen is expressed after the first round of cellular DNA replication, suggesting new drug targets to prevent kidney transplant failure. The study offers a possible solution by targeting host proteins required for re-replication, reducing the likelihood of virus resistance.
The study found that military directors are more inclined to attribute performance shortfalls to the CEO and advocate for stricter accountability, resulting in CEO dismissal. Military directors' influence is more pronounced when serving on a nominating committee.
Anthem's revised policy reverses its previous plan to stop paying for anesthesia care after a certain time limit, a move that would have compromised patient safety. The American Society of Anesthesiologists welcomed the decision, highlighting the need for fair payment for anesthesiologists to ensure adequate care for vulnerable patients.
Researchers at ISTA discovered novel network structures that boost cooperation throughout a system. These structures have the potential to be applied in biology, particularly in bioreactors, to speed up evolution and cultivate microorganisms. The findings could also improve cooperation in computer science-based systems.
Recent studies analyze hurricane damage, water flow into dams, marine heatwaves, and the impact of air pollution on vegetable market prices in South Korea. Hurricane Katrina remains the most damaging U.S. hurricane, while a new system predicts extreme air pollution episodes in India's New Delhi megacity.
Researchers call for a shift away from outdated bathtub modeling, which oversimplifies flood risks, and towards dynamical modeling that accounts for key factors like storm drains and levees. The study found that bathtub models are consistently inaccurate, with scores below 0.5 on the critical success index.