A review of research on childhood adversity sheds light on its long-term consequences on brain development and introduces innovative methods for tackling mental health issues. Emerging factors like societal inequality and pollution are gaining recognition as potential contributors to adverse neurodevelopmental outcomes.
ARDD 2025 to feature Nobel laureates and pharmaceutical executives discussing latest advancements in aging research. Maxwell Biosciences will showcase its CLAROMER technology enhancing innate immune system, promoting healthy longevity.
A new bacterial protein, BeeR, has been identified and its structure is being used to develop protein nanoparticles for targeted cancer drug delivery. The protein forms a hollow tube with a cavity capable of containing drug molecules.
Researchers identify SPP1+ macrophages as critical in CRC development and metastasis, promoting EMT, hypoxia, glycolysis, and immunosuppression. Preoperative chemotherapy reduces SPP1 expression, highlighting a potential role in immunotherapy.
Researchers developed a synthetic mRNA that revitalizes the immune system to recognize and attack metastasizing cancer cells, significantly reducing metastasis in mice and human cells. The treatment shows promise for use in patients with colon and breast cancers, outperforming existing therapies.
A new theme issue in the Canadian Journal of Cardiology emphasizes the importance of personalized heart health advice considering individual differences. The issue highlights disparities in sports participation and related health outcomes between males and females as well as socioeconomic disparities, with women showing a lower risk of...
Researchers at Penn State discovered that Zika virus builds tiny tunnels called tunneling nanotubes to transport material needed to infect nearby cells, including in placental cells. This allows the virus to cross the placental barrier without raising alarm in the immune system.
Research from Edith Cowan University found that increasing muscle strength and cardiorespiratory fitness can reduce all-cause mortality by 31-46% in cancer patients. Regular exercise, including aerobic activities like brisk walking and resistance training, can help extend survival and reduce mortality risk.
Fiji iguanas are most closely related to North American desert iguanas, with a lineage that split around 30 million years ago. The animals likely colonized the Pacific islands after volcanic activity produced land, and their arrival coincided with the formation of Fiji.
European wolf populations have seen a remarkable 58% growth over the past decade, with at least 21,500 individuals now roaming the continent. This recovery is attributed to conservation efforts and policies supporting large carnivore populations.
Scientists have developed a technology called 'audible enclaves,' which can create localized pockets of sound zones where only one person can hear. This innovation uses nonlinear ultrasonic beams to generate a privacy barrier between people for private listening, enabling sound and quiet zones.
Researchers demonstrate a new technique for encapsulating beneficial bacteria that can be stored and applied to plants to improve growth and protect against pests. The technique enables customized probiotics for plants, allowing farmers to use these bacteria in conjunction with agrochemicals.
A new study explores how policymakers can ease the burden of climate threats on people in informal settlements, refugee camps, and war zones. The researchers argue that these 'trapped populations' require tailored policies to adapt in their location or facilitate migration.
Researchers from Saarland University are developing novel air conditioning technology using elastocaloric effect, which can cool and heat more sustainably than current systems. The aim is to commercialize the technology within five years.
A new study found that adenotonsillectomy, a surgical procedure for enlarged tonsils and adenoids, significantly reduces medical office visits and prescription medicine use in children with mild sleep-disordered breathing. The surgery was associated with a 32% reduction in healthcare encounters and a 48% reduction in prescriptions.
A new study from Karolinska Institutet found that patients with heart failure who stop taking medications like RASi, ARNi, or MRA have a higher risk of heart-related death or hospitalization. Despite improved symptoms and pump function, continued medication is crucial to prevent complications.
Researchers identify how a balance of innate structure and flexible learning produces our remarkably organized visual brains. They found that regions in the ventral temporal cortex have distinct cellular organization and white matter connections from birth.
A Cambridge study highlights the need for India to recognize its own sign language, Indian Sign Language (ISL), as a constitutional right. The study also calls for increased investment in education and training programs for deaf and hard-of-hearing students, including more schools and higher education institutions.
A post-treatment blood test measures cancer-derived molecules in patients with lung cancer years after treatment. This tool can inform clinical intervention, including restarting or intensifying treatment for high-risk patients.
A new study in the Circulation Journal reveals that babies born with heart defects may be at a higher risk of developing childhood cancer. Mothers of infants with congenital heart defects also show an increased cancer risk. The study highlights the importance of maternal factors and genetic traits in understanding this connection.
Researchers at the University of Birmingham discovered that presenting information in areas where participants are naturally drawn to it can influence cooperative choices. This is particularly effective when cooperation information is placed at the bottom of the screen, contrary to natural reading patterns.
Researchers from Osaka Metropolitan University used a deep learning model to discover new bubble-like structures in the Milky Way galaxy, providing insights into star formation and galaxy evolution. The study also revealed shell-like structures formed by supernova explosions.
A recent Canadian Medical Association Journal study found no differences in in-hospital deaths or hospital admission rates between people experiencing homelessness and housed patients with severe COVID-19. However, those experiencing homelessness were less likely to be admitted to the intensive care unit or intubated.
Researchers found that placing naloxone kits at public transit locations using an optimization strategy and ensuring blanket placement at take-home naloxone program locations effectively covered a major proportion of opioid poisonings in Vancouver. The study suggests that easy accessibility of kits is crucial to prevent deaths from opi...
Oropouche virus has been reported in travellers from Canada and the US who visited Bolivia, Brazil, Peru, and Cuba, with symptoms including fever, chills, headache, and muscle aches. The risk of miscarriage and microcephaly is high for pregnant individuals, prompting cautionary measures.
A team of researchers developed a highly efficient mesoporous catalyst that can produce hydrogen peroxide even in air supply environments with low oxygen concentrations. The catalyst achieved world-class hydrogen peroxide production efficiencies of over 80% under near-commercial conditions.
A new self-assessment questionnaire has been developed to evaluate the progress of novice nurses during on-the-job training. The Modeling Scale for Novice Nurses assesses four subscales and 21 Likert scale questions to understand the nurses' behavior and growth, enabling senior nurses to provide targeted support.
A study from UC San Diego's Rady School of Management finds that earnings reports can move stock prices in milliseconds, triggering significant movements. The research analyzed over 89 billion after-hours stock quotes and found a spillover effect, where one company's announcement affects other firms' stock prices.
Researchers found that EBV infection activates pyroptosis in intestinal macrophages through upregulation of glycolysis, leading to increased inflammation and disease severity. Inhibiting glycolysis with 2-deoxy-D-glucose may provide a potential therapeutic strategy for UC patients.
The KIT-led ASCCI measurement campaign is analyzing the effects of ozone and water vapor in the Arctic troposphere and stratosphere on climate change. The research focuses on understanding the causes and consequences of Arctic warming, including ozone depletion and air pollutant transport.
A new study found that adding green-synthesised iron nanoparticles (G-nFe) to pig manure neutralises bioavailable copper, reducing environmental risks. The process reduces exchangeable cooper by 66.8%, carbonate-bound copper by 47.5%.
The Tots & Tech Study aims to understand how children and families grow, sleep, move, and interact with technology. Families will participate in 20 hours of activities over three years, earning up to $1,200, with no risks involved.
Researchers found a unique ecosystem in the deep waters of the Farasan Bank coral reef system, where corals and fish adapted to survive in low-oxygen environments. The discovery highlights the need for further marine exploration and conservation of these extreme habitats.
A recent study led by Emily Hackworth and colleagues found that youth with internalizing mental health symptoms are more likely to turn to nicotine products. The analysis showed a strong association between non-combustible product use, including e-cigarettes, and poor mental health among adolescents.
Researchers found that women who became pregnant after the start of the pandemic were more likely to experience preterm birth and low birth weight, regardless of COVID-19 infection severity. Moderate-to-severe infections during pregnancy also increased the risk of adverse outcomes.
Researchers developed a two-stage Transformer-based model that processes hourly and daily time-series data from ICU patients. The model demonstrated robust predictive performance, with an AUC of 0.92 by the fifth day of ICU admission.
A Ben-Gurion University social psychologist argues that toxic masculinity and traditional gender roles impose significant costs on men, affecting their personal and professional lives. Men are pressured to conform to narrow standards of masculinity, leading to increased stress and negative mental and physical health outcomes.
Researchers found that soil micro-food web complexity significantly enhances soil fertility and promotes crop growth, with more complex webs maintaining higher soil nutrient levels. The study provides valuable evidence for improving agricultural yields and optimizing ecosystem management strategies.
Researchers developed a dual bio-/photo-catalytic system for achieving enantioselective hydroamination of enamides, producing diverse enantioenriched vicinal diamines. The system utilizes green light to initiate nitrogen-centered radical reactions, achieving high yields and enantiomeric excess.
Scientists have discovered a potential new treatment strategy for pancreatic cancer by identifying the molecule Neuropeptide Y (NPY) as a key driver of its spread. Blocking NPY's function has been shown to reduce cancer cell movement and metastatic outgrowth, potentially limiting disease progression.
A new study found that poor sleep health is associated with a higher risk of developing Type 2 diabetes among women with a history of gestational diabetes. Women who slept six hours or fewer per night had a 32% higher risk compared to those who met the recommended seven to eight hours of sleep.
The ASCOLT trial found that aspirin does not statistically improve disease-free survival for all patients but demonstrates a consistent trend of improving overall and disease-free survival. Aspirin taken for up to 3 years is efficacious in patients with PIK3CA mutation, reducing recurrence by over 50%.
A recent study found that a sulfur amino acid restriction diet induces rapid fat loss and enhances glucose sensitivity in mice without impacting appetite or physical activity. The study identified cystine as a key regulator of fat metabolism, suggesting its potential implications for weight management in diabetic patients.
Researchers from Kumamoto University and colleagues found that left-right symmetry-breaking occurs prior to node formation, indicating a tightly regulated program for asymmetry. This study demonstrates the involvement of physical mechanisms in biological patterning using quantitative biophysical parameters.
Research published in the European Heart Journal suggests that Australia's burden of cardiovascular disease caused by extreme heat will more than double by 2050. The study found that hot weather costs around 49,483 years of healthy life annually, with this number expected to increase significantly under climate change scenarios.
A study published in Political Science Research & Method found that around one in six people falsely recall the party affiliation of a politician, with those who admire a hero more likely to see it as their own party. Researchers say this projection could be fuelling polarisation in politics.
This groundbreaking research systematically reviewed construction robots' scientific technologies and progress in extreme environments, including hazardous work environments, polluted environments, and harsh natural environments. The study elucidated four key technical performance aspects: mechanism, perception, planning, and control.
Researchers at Cleveland Museum of Natural History propose that early humans used naturally sharp rocks as cutting tools before developing their own stone technology. This new hypothesis challenges current understanding of the origin of stone knapping, suggesting a more extensive use of natural resources than previously thought.
A recent study identified 26 viral species from ticks in Hulunbuir, including four novel viruses and 11 new strains of human-pathogenic viruses. The study highlights the potential spillover risk of these viruses and underscores the need for One Health strategies to monitor emerging tick-borne viruses.
The platform has been clinically proven to significantly increase levels of confidence for most users after a single 30-minute session. A week of self-guided use was beneficial to 100% of participants, helping them feel more prepared, adaptable, resilient, confident, and able to manage nerves.
The summit will highlight the latest research on coronavirus, plant-based protein, and probiotics, with a focus on their applications in clinical practice. Studies have found that COVID-19 affects the gut microbiome in children, while dietary protein like S100B may promote a healthy microbiome.
Researchers have developed new methods to boost chiral optical signals, including tailoring optical fields, photonic resonance, orbital angular momentum beams, metasurfaces with bound states in the continuum, and nonlinear optics. These strategies offer promising avenues for further research in chiral optics and its applications.
A new free VR platform has been launched to help people overcome public speaking anxiety, with clinical trials showing significant increases in confidence after a single 30-minute session. The platform uses Overexposure Therapy to build adaptability, grit, and resilience through repeated practice in extreme scenarios.
A global survey of over 30,000 people found that those from the Global South are more hopeful about climate change, leading to increased support for climate interventions. Meanwhile, European countries express strong anger and sadness towards climate change, highlighting the need for diverse perspectives in addressing the crisis.
A new AI model developed by UC Riverside scholars combines historical sales data with economic demand theory to predict prices in uncertain times. The model retains high accuracy, demonstrating a substantial improvement over other methods in reducing generalization errors.
Researchers have created a new open-source tool to optimize the placement of visual brain implants on a large scale. The tool, developed by the Netherlands Institute for Neuroscience, uses data from participants with intact vision to predict optimal implant locations and minimize safety risks.
Researchers at Annenberg Public Policy Center found that using 'I Will Vote' stickers significantly enhances voting intentions and attitudes towards voting. The study suggests that a future-oriented perspective promotes thoughts about outcomes and planning, strengthening citizens' capacity to successfully perform the intended behavior.
The study reveals that a high magnetic field significantly affects the directional solidification microstructure of the Al–18 at.%Ni alloy, causing hypereutectic reactions instead of peritectic reactions. The preferred orientation of the Al3Ni phase is also influenced by the growth velocity.
A new study from Colorado State University found that fortified corrals can reduce livestock losses due to predator attacks on nearby carnivores. The study demonstrated a beneficial spillover effect where households neighboring those with chain-link corrals also reported fewer attacks on their livestock.
A new study finds that an open-source AI model, Llama 3.1 405B, has caught up with a leading proprietary model, GPT-4, in solving challenging clinical cases. This development could offer a valuable alternative to proprietary models, benefiting patients and clinicians alike.