Fibro-adipogenic progenitors (FAPs) influence muscle regeneration, fibrosis, and degeneration through inflammatory cytokines. IL-33 secreted by FAPs plays a crucial role in muscle injury repair and recruiting regulatory T cells.
Northeastern University researchers develop a new material that cools high-power laser systems while increasing luminous efficiency by 73.2%. The breakthrough enables practical, high-performance laser lighting technologies with improved thermal stability.
Researchers in New Zealand are shedding light on the prevalence of dementia in multicultural communities, revealing up to half of those affected are unaware they have the condition. Early diagnosis can be life-changing, providing access to social support and improving quality of life for both individuals and caregivers.
A multidisciplinary study reveals Middle Paleolithic Quina technology in East Asia, dating back to approximately 60,000-50,000 years ago. The discovery suggests potential Neanderthal dispersal into Southwest China and reshapes the understanding of East Asia's evolutionary landscape.
Research finds that strengthened westerly winds enhance clockwise oceanic circulations, transporting warm seawater and causing accelerated ice sheet melting in East Antarctica. This study's findings improve future sea level rise projections.
Three UVA Engineering faculty members, Scott T. Acton, Gustavo Kunde Rohde and Shannon Barker, have been named to the 2025 class of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. They are recognized for their contributions to biomedical engineering research, innovation, teaching and leadership.
A new study from USC Dornsife's Brain and Creativity Institute found that nostalgic music engages the brain's default mode network linked to memory and self-reflection, as well as its reward circuitry. This discovery could support emotional well-being and cognitive function in individuals with memory impairments.
A new study achieves substantial wavelength tuning at ambient conditions, surpassing previous reports by an order-of-magnitude. The breakthrough enables the development of programmable light sources with potential applications in secure quantum communication and photonic-based computing.
Researchers at USTC identify a novel approach to preventing acute graft-versus-host disease (aGVHD) in allo-HSCT by considering the recipient's circadian rhythms. Infusing stem cells early in the day can efficiently reduce the incidence and severity of aGVHD.
Researchers developed a method to visualize different types of chromatin and revealed distinct physical properties. They found that euchromatin is more flexible and dynamic, while heterochromatin is more rigid and static. This discovery changes how scientists think about chromatin and its role in regulating gene function.
The Golden Light Sutra, a 1,000-year-old Chinese translation of a Buddhist scripture, is now freely accessible online via Kyushu University Library's digital archive. The collection offers valuable resources for studying the history of Japanese language and literature.
A new study by Edith Cowan University found that people who pursue goals for reasons connected to relationships experience greater happiness and wellbeing, while those driven by external pressures report lower levels. The study also suggests that personally autonomous motivation is generally associated with personal wellbeing.
The study found that Semen podocarpi extract (SPE) promotes apoptosis, arrests cell cycle, and presents radiosensitizing effects on radioresistant nasopharyngeal carcinoma cells. SPE regulates the Raf/MEK/ERK signaling pathway, increasing C-Raf gene expression and reducing ERK1 and ERK2 protein levels.
Researchers developed an AI algorithm to help surgeons position knee components in a way that better matches each patient's natural anatomy. Patients with naturally bowed legs responded well to the 'functionally aligned' knee surgery, reporting better outcomes.
Trigonelline effectively mitigates SCI-induced changes in behavioral tests, biochemical markers, and histological damage in rat models. The compound downregulates apoptotic and inflammatory markers while upregulating neurotrophic factors.
The ALL ALS Consortium has recruited over 300 participants across two studies, ASSESS and PREVENT, aiming to disrupt traditional ALS research by making data and samples available worldwide. The consortium seeks to discover new drug targets and approaches for effective treatments.
A new study from Mass General Brigham identified patients with heart ultrasound results indicating thickened heart muscle, a condition often caused by hypertension. The study used natural language processing to analyze electronic health records and found that physicians were nearly four times as likely to diagnose hypertension and pres...
A new study found that reported tuberculosis diagnoses among incarcerated people in Europe and the Americas plummeted by up to 100% during the pandemic, despite consistent incarceration rates. This reduction was distinct from general population trends, highlighting the need for improved healthcare systems within prisons.
A new Electronic Frailty Index 2 (eFI2) system will improve the accuracy of identifying older people's frailty by integrating data on 36 health problems. This will enable GPs to provide personalized treatments to prevent costly loss of independence and falls in older age.
Artificial neural networks trained on spontaneous retinal activity patterns show improved motion prediction in natural scenes. The approach also enhances performance when combined with naturalistic movie data.
A complete Quina technological system, used for making tools, was discovered in southwest China dating back 50,000 to 60,000 years. This finding disputes the widely held belief that development in China was sluggish during most of the Paleolithic period.
Researchers explore fluid dynamics of stentors' cooperative feeding behavior, discovering that grouping together generates more powerful flows to sweep in food from a greater distance. This finding could provide insight into how single-cell organisms evolved into complex organisms like humans.
Researchers found that whales and dolphins use a unique sleep strategy by turning off one half of their brain at a time. This phenomenon is enabled by specific genes and pathways that enable secondary aquatic adaptation.
The SUMMIT trial shows tirzepatide reduces the risk of cardiovascular death or worsening heart failure in patients with obesity, chronic kidney disease, and heart failure, while improving kidney function. Researchers found significant improvements in both patient groups with and without chronic kidney disease.
Nurses in states with abortion bans face communication gaps and moral distress when providing care to pregnant patients. They resort to 'work-arounds' like reading the room for allies or using online resources to find legal reproductive health care, highlighting the need for better guidance and support.
A new study from the University of Ottawa's Human and Environmental Physiology Research Unit has validated lower limits of human heat tolerance, highlighting the urgent need to address climate change impacts on human health. The research found that many regions may soon experience conditions exceeding safe limits for human survival.
The Fred Young Submillimeter Telescope (FYST) has arrived at its final home in Chile's Parque Astronómico Atacama after a six-week ocean voyage and trekking through the mountains. The telescope will study cosmic dawn, star and galaxy formation, and gravitational waves from the Big Bang.
Researchers at Mass General Brigham have developed a new hydrogel that continuously releases medication without breaking down under mechanical stress. The hydrogel showed promising results in preclinical studies, significantly reducing cartilage damage and improving joint lubrication.
Researchers at University of Liège have developed a method for rapidly creating NOON states with ultra-cold atoms, accelerating the process by a factor of 10,000 while maintaining high fidelity. This breakthrough opens up prospects in quantum metrology and quantum information technologies.
A study found that only a quarter of mental health providers correctly diagnosed bulimia nervosa, with common misdiagnoses including binge eating disorder. Excessive exercise is often overlooked as a compensatory strategy used by people with bulimia.
The MOPEVACLAS vaccine candidate is being tested in a Phase I clinical trial for its safety and immune response in humans. The vaccine targets Lassa fever, a hemorrhagic disease responsible for thousands of deaths worldwide each year.
UT Dallas researchers have invented a mandrel-free method for fabricating springlike polymer muscles with high-spring-index yarns. These muscles can significantly contract and elongate due to their large spring index, enabling applications in comfort-adjusting jackets and mechanical energy harvesting.
A study found that patient navigators significantly improved one-year follow-up colonoscopy completion rates by 12% and reduced time to follow-up by 27 days. The researchers emphasize the importance of timely follow-up colonoscopies for patients with abnormal stool test results.
Researchers at Mayo Clinic are conducting a study to understand the factors that contribute to rapid progression of dementia in patients with Alzheimer's disease and Related Dementias. The team aims to identify biomarkers and disease-modifying targets that can improve diagnosis and treatment outcomes for these patients.
Dr. Hui Shen, a leading expert in bioinformatics and computational biology, has been elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. Her research focuses on cancer prevention, detection, and treatment by studying epigenetics, leading to breakthroughs in ovarian cancers and enhanced u...
Researchers developed a novel blood test that accurately indicates spinal cord injury (SCI) severity and predicts potential recovery. The test identifies multiple biomarkers, including DNA and proteins, to rapidly diagnose SCI and project long-term neurological functional recovery.
Dr. Christopher Kramer began a one-year term as head of the American College of Cardiology, addressing workforce issues, health equity and AI-driven solutions to improve cardiovascular care. With over 35 years of membership and leadership roles, Kramer brings experience in cardiovascular magnetic resonance imaging.
Police reports of hate crimes in 42 major US cities declined 2.7% in 2024, with anti-Jewish and anti-Muslim hate crimes rising 12% and 18%, respectively. Anti-Jewish hate crimes reached record levels in several cities, while anti-Asian hate crimes fell more than 14%. The upward trend is attributed to the timing of the Israel-Gaza war.
A Yale-led study finds that global climate change may devastate butterfly habitats, turning mountain ecosystems into traps and eroding temperature niches. The researchers urge conservation efforts to protect key habitats and migratory corridors to ensure butterfly diversity survives.
The Flatiron Institute's Center for Computational Astrophysics is now supporting MESA's ongoing maintenance and development after its creator Bill Paxton steps down. The center has hired Philip Mocz as a full-time software engineer to ensure MESA's continued growth and impact in stellar physics.
A new report by Michigan State University and Michigan Public Health Institute found that shootings in Lansing fell after the implementation of a prevention program, with some variations between years and communities. The Advance Peace Lansing program employs fellows to engage with individuals affected by gun violence.
The Association for Molecular Pathology (AMP) has won a court ruling that vacates the FDA's rule on laboratory-developed test procedure regulation. This decision will avoid adding billions of dollars in healthcare costs and protect access to high-quality care for hundreds of millions of Americans.
A randomized clinical trial found that 4:3 intermittent fasting resulted in modestly greater weight loss over 12 months compared to daily caloric restriction. The study showed improved cardiometabolic outcomes, including lower blood pressure and cholesterol levels, suggesting that fasting may be a more effective approach for weight loss.
The University of Texas at Arlington has launched a new Mobile Simulation Lab to tackle workforce and training challenges in rural areas. The lab, equipped with advanced patient manikins and simulation bays, will provide specialized training for local healthcare providers to expand their expertise.
The new facility will offer a range of services including ambulatory surgery, expanded diagnostic imaging, and outpatient procedural services. It is designed to provide comprehensive cancer care for adult patients with low-to-medium acuity needs.
Dr. David Winchester will lead the American College of Cardiology's Board of Governors, guiding chapters representing all 50 states and promoting heart health improvement in communities. His term aims to address practice challenges through advocacy and chapter support.
Fossil fuels are driving interlinked crises that threaten people, wildlife, and a livable future. The review highlights the importance of transitioning to clean, renewable energy and materials across the economy.
A new species of the elusive 'fairy lantern' genus Thismia has been discovered in eastern Peninsular Malaysia. The critically endangered species, Thismia aliasii, relies entirely on fungi for its nutrition and is threatened by habitat degradation due to increasing hiking activities.
A recent study found that individuals with reduced slow wave sleep and rapid eye movement sleep had smaller volumes in critical brain regions, particularly the inferior parietal region. This association suggests a potential link between sleep deficiency and brain atrophy, which may increase the risk of Alzheimer's disease.
Researchers have developed a method for synthesizing carbon nanotube-supported intermetallic RuM alloys with sub-5 nm nanoparticles using ultrafast laser confined alloying. These alloys exhibit excellent electrochemical catalytic activity and robustness, outperforming commercial benchmarks and existing catalysts.
A new study found that people with PTSD symptoms experience greater fear of their emotions, which is associated with less constructive communication and more unproductive communication in romantic relationships. This fear can lead to a vicious cycle where behavior triggered by PTSD symptoms strain relationships, maintaining PTSD symptoms.
A recent study published by CU Center for COMBAT Research investigators found that targeting slightly lower levels of oxygen saturation, from 90-96%, had similar outcomes for adult trauma patients. This approach resulted in fewer days spent on supplemental oxygen and reduced hospital stays.
Researchers developed a new viscoelastic model of enzymes, elucidating the intertwined effects of elastic forces and friction forces on enzyme function. This breakthrough allows proteins to be perceived as soft robots or programmable active matter, revolutionizing our understanding of enzymatic catalysis.
A new study resolves the long-standing debate on low-pressure phase transitions in HfO2 by combining high-pressure experiments, spectroscopy, and calculations. The research reveals two distinct orthorhombic phases and finds that doping with yttrium reduces transition pressures.
Approximately 1,900 US scientists warn that the Trump administration's actions are slowing scientific advances and harming Americans. The experts argue that gutting funding for research, firing scientists, and removing public access to data will damage the economy and national security.
Researchers have discovered that common anticancer drugs can reduce vascular growth in patients with PTEN Hamartoma Tumour Syndrome, offering new hope for treatment. These findings were made possible by the development of a mouse model and clinical trials using rapamycin and capivasertib inhibitors.
A new study by researchers at McGill University found that annual COVID-19 vaccine booster doses help avoid breakthrough infections in people with immune-mediated inflammatory diseases. The study tracked 366 patients across Canada and used saliva PCR tests and antibody measurements, offering a more precise picture of infection risks.
Between 2015-2020, 893,430 pregnant women were identified with a cannabis use disorder diagnosis, resulting in 1,058,448 total pregnancies. The cumulative prevalence of CUD diagnosis was 0.26%. Clinicians are well-positioned to intervene but may lack structural support due to fear of legal repercussions and underestimated diagnoses.
In extremely thin films of niobium diselenide (NbSe₂), superconductivity becomes confined to the surface when thinner than six atomic layers. This discovery challenges previous theories and could have important implications for understanding superconductivity and developing advanced quantum technologies.
A new study reveals significant barriers to including non-English speakers in health research, with common reasons including lack of training and budget constraints. Researchers recommend increased access to interpretation and translation services, guidance on budgeting, and methods training to improve inclusion.