A newly described microendemic gecko species has been found in three small forest fragments in south-eastern Madagascar. The species, Paragehyra tsaranoro, is critically endangered due to habitat loss and fragmentation, highlighting the importance of protecting its cultural heritage.
Researchers have captured the first microscopy images of atomic thermal vibrations in quantum materials, revealing a new type of motion that could reshape the design of quantum technologies and ultrathin electronics. The breakthrough study uses electron ptychography to map thermal vibrations with atomic precision for the first time.
The conference will feature keynote speakers Donna Ryan and Erik Wilson, as well as informative presentations and breakout sessions on the latest advances in obesity research. The Louisiana Obesity Society aims to support healthcare providers treating obesity through education and networking.
Researchers from HSE MIEM have demonstrated that controlled defect distribution, or correlated disorder, can enhance superconductivity in materials, allowing it to occur at higher temperatures and extend throughout the entire material. This finding could lead to the development of superconductors that operate without extreme cooling.
Researchers have engineered novel microbial cell factories capable of utilizing methanol to produce high-value chemical intermediate α-farnesene. The engineered strain achieved a yield of 3.28 g/L, establishing an effective strategy for low-cost and sustainable biomanufacturing.
Researchers at MIT develop a new method to directly measure the strength of electron-phonon interaction in semiconductors, a crucial property for next-generation microelectronic devices and quantum computers. This approach leverages an oft-overlooked interference effect in neutron scattering to detect electron-phonon interactions.
ShadeLA aims to reduce heat risk by expanding tree canopy and shade infrastructure in key public spaces, targeting major sporting events and heat waves. The initiative builds on USC's Urban Trees Initiative and engages community-based organizations to create locally driven solutions for a more comfortable L.A.
Researchers propose a synergistic combination strategy using systemic type I interferons (IFN-I) and local TLR7/8 agonists to enhance dendritic cell activation and inhibit metastatic tumors. This approach enhances early innate immune control and later induces CD8+ T cell responses.
In a breakthrough study, researchers at the University of Rochester Medical Center found that microglia cells respond differently than neutrophils to photoreceptor damage in the retina. This discovery has high implications for treating vision loss caused by photoreceptor cell damage.
A four-level hierarchical framework has been developed to standardize all experimental processes in biofoundries, facilitating the accumulation of high-quality process data usable in AI applications. This structure enables consistent recording, sharing, and automation of complex biological experiments.
Research suggests that fresh grapes possess numerous health benefits due to their high antioxidant content, including promoting relaxation of blood vessels, healthy circulation, and modulating cholesterol levels. Grapes have also been shown to support brain, skin, gut, and eye health through various mechanisms
A recent study published in JAMA Network Open found that glipizide, a commonly used type 2 diabetes medication, is associated with a 13% increase in cardiovascular risk compared to dipeptidyl peptidase-4 (DPP-4) inhibitors. The study analyzed data from nearly 50,000 patients and found that glipizide was linked to higher rates of heart ...
Researchers have discovered a new species of deep-sea limpet, measuring up to 40.5 mm in shell length, found 5,922 meters beneath the northwestern Pacific Ocean. The species, named Bathylepeta wadatsumi, has broader ecological implications as it appears to graze on sediment layers over rock.
Researchers at King's College London discovered that ketamine's antidepressant effects involve the brain's opioid system, which works together with glutamatergic systems to produce rapid treatment effects. The study also identified a sex-related effect, where males with depression showed a more pronounced response to naltrexone.
A team of researchers from Waseda University investigated the effects of new communication media, including video-conferencing and embodied virtual reality, on self-disclosure. They found that embodied VR, especially with unrealistic avatars, resulted in higher self-disclosure of personal feelings compared to face-to-face conversations.
A multi-university team has developed a system combining magnetic steering and light-triggered release for precise targeted drug delivery. The researchers successfully steered microscopic drug delivery containers using magnetic fields, advancing the development of precision medicine.
A study found that SARS-CoV-2 infection caused different long-term consequences in lean and obese macaques, with obesity increasing risks like persistent lung damage. Lean animals also experienced signs of metabolic disruption, suggesting long COVID may be more common than reported.
Researchers developed a new, thermally stable T7 RNA polymerase that reduces harmful double-stranded RNA byproducts and improves mRNA biocatalyst efficiency. This innovation has potential for novel vaccines and treatments targeting various diseases.
Researchers at USC have developed a new understanding of how the human brain organizes its visual memories by sorting them into categories. The study, published in Advanced Science, used human patient brain recordings and machine learning to decode the category of visual image being recalled from precise neural timing.
The Karlsruhe Institute of Technology (KIT) and the Joint Research Centre (JRC) are conducting joint research on nuclear safety and security. The partnership aims to train young researchers and develop innovative tools for nuclear applications, with a focus on medical research, space travel, and decommissioning nuclear facilities.
A new ventilation mode called proportional assist ventilation (PAV+) has been found to improve outcomes for critically ill patients on ventilators. PAV+ reduces the need for sedation and delirium in ICU patients, leading to faster recovery times.
The study reveals that the optimal penetration of grid-forming converters depends on a delicate balance between stability requirements and economic considerations. The researchers found that dynamically adjusting the share of GFMs strengthens system security while reducing total system costs.
A new microscopy technique allows scientists to observe active cells, even in the presence of diseases, and understand how drugs interact with living tissues. The technique has been made available to the scientific community as Open Science, enabling rapid dissemination and further innovation.
A team of scientists from the University of Konstanz has identified the PPM1F enzyme as essential for cell migration in both embryonic development and tumor cell invasion. The study found that increased levels of PPM1F enhance the invasive potential of cancer cells, while its absence impairs cell adhesion and migration.
A new study by Boston University School of Public Health and Harvard T.H. Chan School of Public Health found that energy-efficient strategies can have a significant impact on public health in the European Union. The research reveals dramatic differences in health burdens from electricity use based on the source of energy used, with cou...
A new study finds that risk-reducing mastectomy is cost-effective for women aged 30-55 with a lifetime breast cancer risk of 35% or higher. The findings have significant clinical implications, suggesting that RRM could expand access to the procedure beyond BRCA1/BRCA2/PALB2 pathogenic variant carriers.
A new analysis suggests that preventive mastectomy is a cost-effective way to reduce the likelihood of developing breast cancer compared to breast screening and medication. Women aged 30 or above with a lifetime breast cancer risk of 35% or more may benefit from this treatment option.
Bonn researchers reduce cardiac arrhythmia after heart attacks by using gene therapy to overexpress connexin 43 in fibroblasts of cardiac scar tissue, leading to improved electrical connection between cells and reduced arrhythmias.
Complex organic molecules, precursors to life's building blocks, have been found in a planet-forming disc around the outbursting protostar V883 Orionis. This discovery supports the idea that life's seeds are assembled in space and are widespread.
Researchers have created a new catalyst with an asymmetric single-atom site that dramatically enhances oxygen reduction reaction efficiency. The unique honeycomb-like structure exposes more active sites, improving mass transport and performance.
A study published in the Journal of the American College of Surgeons found that older adults with serious illness before undergoing elective surgery had significantly longer hospital stays, higher rates of readmissions, and almost double the yearly costs of healthcare compared to their counterparts. Depression was found to be a signifi...
Researchers from Northwestern University developed a novel approach to integrate metal-sulfur active sites into metal-organic frameworks, which significantly outperformed their non-sulfur counterparts in hydrogenation catalysis. The study provides a powerful new strategy to design and study metal-sulfur catalysts for various applications.
A new study by the University of Surrey investigates how our brains process face pareidolia and averted gazes, revealing differing mechanisms that influence attention. The researchers found that participants shifted their attention in response to both real faces and imagined face-like objects.
EPFL researchers have developed a 'self-driving' imaging system that can track and analyze protein aggregation in real-time and even anticipate its onset. The approach minimizes the use of fluorescent labels, allowing for accurate analysis. The new technology has important implications for drug discovery and precision medicine.
Researchers discovered complex structures in millipede secretions that can modulate specific neuroreceptors in ant brains, shedding light on potential new medications. The newly found alkaloids, named andrognathanols and andrognathines, have shown potent interactions with the Sigma-1 neuroreceptor.
A new analysis finds that delinking PBM compensation from list prices could lower US annual drug spending by nearly $100 billion. Shifting to a transparent payment model would reduce costs without undermining pharmaceutical innovation, according to USC Schaeffer Center Director Geoffrey Joyce.
A recent study found that a 5 mg dose of olanzapine taken after chemotherapy significantly reduced nausea and vomiting in breast cancer patients, with fewer side effects compared to the standard 10 mg dose. The low-dose regimen was effective for both immediate and delayed symptoms, making it an attractive alternative for patients.
A new method harnessing CYGNSS significantly improves soil moisture retrieval by eliminating vegetation interference and removing dependency on external datasets. The technique enables standalone, high-frequency monitoring of soil moisture, offering a transformative tool for climate research, agriculture, and disaster management.
A novel deep learning approach estimates TOA shortwave radiation using DSCOVR/EPIC satellite images, overcoming traditional challenges and improving accuracy. The method is validated against established CERES data products with a high correlation rate.
A recent study by Florida Atlantic University reveals that up to 40% of hospital transfers from nursing homes can be avoided. The study identified common medical conditions linked to unnecessary hospitalizations, including feeding tube complications and urinary tract infections.
The study found that most plastic bottles and caps on Pacific coast beaches in Central America originated from local companies, while Asian origin bottles were more common on island coasts. The research sampled over 12,000 kilometers of coastline and collected over 92 mainland beaches, 15 island beaches, and 38 human settlements.
Researchers developed an AI platform to design proteins that arm immune cells to attack and kill cancer cells. The method reduces the process from years to just 4-6 weeks, offering a new approach to precision cancer treatment.
Researchers developed a novel deep learning-based framework that improves five-day regional weather forecasting accuracy, even with limited data. The method achieved significant improvements in temperature, precipitation, and wind speed forecasts, outperforming mainstream global AI models.
The H-SUP system offers a portable fuel cell electric generator with greater energy per weight than batteries and lower audible and thermal signatures. The system supports distributed operations, extends mission range, and increases lethality of the force.
Researchers found that ibogaine significantly improves cognitive function and reduces PTSD symptoms in veterans with TBI. The study suggests that stronger theta rhythms may promote neuroplasticity, while reduced cortical activity may alleviate PTSD symptoms.
A study by Kaunas University of Technology reveals that digital mental health platform start-ups prioritize simple, scalable services and use subscription models to achieve success. State funding can hinder development rather than encouraging it to become a unicorn.
A wearable technology enables precise drug dosing through continuous monitoring of disease and drug markers, solving the problems of invasive and painful current technologies. The system combines microneedles, nano-enzyme-based sensors, and a smartphone app to provide real-time pharmacologically guided diabetes treatment.
A recent study published in The EMBO Journal reveals that the Setd8 gene plays a critical role in the premature aging of the brain by controlling neural stem cell activity and proliferation. Artificially lowering Setd8 levels mimicked molecular signatures of aging, highlighting its potential as a biomarker for early aging.
An international team of coral scientists calls for urgent regulatory reform to support assisted gene flow, a powerful tool to boost coral resilience. The researchers outline reforms needed to enable cross-border coral exchanges to introduce new genetic diversity and preserve coral diversity.
A nationwide study in Ukraine found substantial lifetime exposure to hepatitis B and C viruses, with significant ongoing circulation among the population. The study emphasizes the need for hepatitis B vaccination among infants and risk groups, as well as regular screening, treatment, and awareness-raising efforts.
Two research teams will use AI to advance screening and treatment for cardiovascular disease, a leading cause of death in the US. The projects aim to improve health outcomes and save lives by detecting early signs of kidney and liver disease, as well as personalizing CPR techniques.
Researchers at Fralin Biomedical Research Institute have identified a potential target for experimental drugs that block PRMT5, a naturally occurring enzyme some tumors rely on for survival. The study found a new drug combination that works against certain hard-to-treat cancers.
A plant virus, cowpea mosaic virus (CPMV), has shown promise as a low-cost and potent cancer immunotherapy. CPMV stimulates type I, II, and III interferons, which have well-known anti-cancer properties, and activates toll-like receptor 7 to prime antiviral and anti-tumor immune responses.
Researchers found that standard DNA testing does not detect NUT carcinoma fusion genes in over 75% of patients. Additional tests like NUT immunohistochemistry and RNA fusion testing can reliably identify gene fusions, leading to more accurate diagnoses and potentially life-saving treatments.
Worcester Polytechnic Institute has received a National Science Foundation grant to study an electrochemical system for removing insoluble mineral deposits in water treatment. The goal is to develop a lower-cost, environmentally friendly system that can selectively remove scale-forming cations and prevent the buildup of harmful minerals.
The Obesity Society has appointed a new CEO, Sherlyn Celone-Arnold, and several key experts to its leadership team, enhancing its commitment to addressing obesity through innovative strategies and expert guidance.
Researchers developed a new defense strategy, LSH-FL, to protect federated learning from poisoning attacks in healthcare, autonomous vehicles, and finance. The approach maintains accuracy losses below 1% using short-term perturbations and long-term gradient history, ensuring secure and private decentralized AI.
A team of researchers has discovered that ancient nectocaridids, thought to be cephalopods, are actually an early descendant of arrow worms. This finding reveals complex predators in the food chain and sheds light on the evolution of these creatures.
Two studies found that industrial fishing is rare in fully and highly protected marine areas, averaging just one vessel per 20,000 square kilometers. However, nearly half of the world's coastal MPAs showed evidence of industrial fishing, with factors like MPA size and remoteness more predictive of fishing presence than official protect...
A research team has experimentally demonstrated a nonlinear wave phenomenon that changes its frequency depending on the direction of incoming waves. The system exhibits different responses to waves entering from one side versus the other, with potential applications in medical ultrasound imaging and noise control.
A recent study published in Brain reveals that a mathematical model can classify genes into four categories based on their interaction with the brain's network patterns. This classification helps explain why some brain regions deteriorate rapidly while others remain intact, providing new insights into Alzheimer's disease.
Chronic cellular senescence disrupts tissue homeostasis, creating a self-propagating
Researchers found that ChatGPT-4 performed better across demographic groups, while LLaVA showed significant sex-related biases in diagnosing skin diseases from medical images. The study emphasizes the need to address these biases to ensure AI models are safe and effective for all patients.
Researchers at National Institutes for Quantum Science and Technology developed a technique to decompose polytetrafluoroethylene (PTFE) into gaseous products using electron beam irradiation. This process reduces energy required by 50% compared to traditional methods, making large-scale recycling of fluoropolymers more viable.
The study reveals significant differences in transition duration, location, and mechanism among four clusters of ETCs. Recurving ETCs undergo transition during track recurvature, while westward ETCs transform rapidly after landing. Northwestward ETCs typically undergo transition in the baroclinic zone, and abnormal track ETCs complete ...
A new study reveals that fully and highly protected marine reserves successfully curb industrial fishing activity, offering a powerful new way to assess fishing compliance. The research combines satellite imagery and AI technology to detect previously untraceable vessels, finding that most MPAs are well-respected and effective in deter...
A study published in iScience found that cells in breast tissues of women with African ancestry send cues promoting breast cancer growth. Researchers discovered that PZP cells activate epithelial cells, allowing them to invade surrounding tissue.
VCU Massey Comprehensive Cancer Center is the first US site to enroll patients in a global Phase 2a clinical trial of PTX-100, a small molecule inhibitor for cutaneous T-cell lymphoma. The trial aims to evaluate the efficacy and safety of PTX-100 in patients with relapsed or refractory disease.
A new study uses deep learning to map microscopic structures and simulate mass transport in CO₂RR catalyst layers, providing a scalable blueprint for industrial CO₂ electrolyzers. By optimizing catalyst layer composition, high current densities can be sustained without sacrificing selectivity or durability.
A recent study by JAMA Network Open reveals racial differences in care quality among men with newly diagnosed prostate cancer. Black men had lower odds of overtreatment, suggesting better care, while having lower odds of confirmatory testing on active surveillance, indicating worse care.
Researchers have identified two brain waves, alpha and delta waves, as key markers for obsessive-compulsive disorder (OCD). These findings could lead to more targeted deep brain stimulation treatments, improving outcomes for patients. The discovery provides a significant breakthrough in understanding OCD and its neural mechanisms.
A new study has identified genetic changes in the parasite responsible for trichomoniasis that may have helped it adapt to human hosts. The research found dozens of genes associated with key functions such as phagocytosis and exosomes, which could be exploited for future treatments.
Researchers discovered antibiotic-resistant Staphylococcus saprophyticus in the Southern Ocean, showing complete resistance to multiple antibiotics. The study highlights the need for greater awareness of human impact on pristine ecosystems like Antarctica, which may exacerbate public health issues through the food chain.
Researchers found that billing codes may mistakenly identify diseases in up to 45% of cases, highlighting a significant limitation in using administrative data for clinical research. The study examined records of 1.36 million patients and found discrepancies between coded diagnoses and actual disease presence.
A new study has found that TAF1 operates as a key molecular switch in adult hematopoietic stem cell maintenance and lineage commitment. This discovery challenges prevailing models of gene regulation and has the potential to lead to new therapeutic strategies targeting the molecule, which could improve blood production and transplantation.
Answer ALS is launching a groundbreaking collaboration with Tulane University and the Pennington Biomedical Research Center to harness AI for ALS treatment discovery. The Louisiana AI Drug Development Infrastructure for ALS (LADDIA) will prioritize therapeutic targets using AI-driven insights from the Answer ALS' Neuromine Data Portal.
The Josep Carreras Leukaemia Research Institute is launching a joint research programme on childhood leukaemia, aiming to develop common strategies and improve treatments for the disease. Paediatric leukaemia remains a significant challenge due to its low incidence and high mortality rate.
Physicists developed a method to control atomically thin semiconductors using terahertz light pulses, enabling ultrafast signal control devices. The technique allows real-time control of electronic structure on timescales of less than a picosecond.
Colorectal cancer claims more lives in Black communities than any other racial group, with incidence and mortality rates about 20% and 30% higher respectively. A new review by UCLA researchers highlights the need for equal access to screening, diagnosis, and treatment to eliminate these disparities.
Recent advances in chemistry have led to innovations in industrial carbon capture technologies, reducing energy consumption by over 30% and improving efficiency. The research highlights novel amine blends, metal-organic frameworks, and electroswing technologies that can selectively capture CO2 with high efficiency.
Scientists discovered that marine copepods rely on both genetic and epigenetic changes to survive climate change. Epigenetic changes, which are temporary chemical modifications, play a crucial role in helping these tiny crustaceans adapt to ocean acidification and warming conditions.
Researchers have discovered star-shredding black holes in dusty galaxies, confirming that these events are powered by dormant black hole accretion. The study uses the James Webb Space Telescope to detect clear fingerprints of black hole activity in four galaxies, revealing key differences between active and dormant black holes.
A recent clinical trial found MyMenoplan.org effective in increasing treatment intentions and menopause knowledge among users. The website offers personalized information and decision-making tools, guiding women through symptom discussions and outlining treatment options.
Researchers found that certain antibodies can reduce antitumor immune cells, highlighting the need to consider ADCC activity when designing or selecting ICI therapeutics. This study could help improve cancer treatment by engineering antibodies that avoid damaging essential immune cells.
A new study reveals a significant association between neighborhood firearm violence exposure and adolescents' perceived ability to obtain a firearm outside the home. Fighting behavior was found to mediate 32% of the relationship, highlighting the layered risks faced by youth in high-violence settings.
Research found passing rates peak at noon, lowest in early morning and late afternoon, with implications for high-stakes evaluations like job interviews. Strategies like quality sleep and mental breaks can help counteract time-of-day effects.
Tonic signaling in CAR-T therapy allows for precise tuning of signaling intensity and duration, enabling personalized treatment optimization. By balancing activation thresholds and duration, researchers can predict therapeutic efficacy and mitigate exhaustion.
Researchers have engineered a novel enzyme, PET2-21M, to enhance the biodegradation of bottle-grade polyethylene terephthalate (PET) plastics. This breakthrough offers a sustainable and efficient alternative to conventional recycling processes, achieving significant improvements in catalytic activity and substrate efficiency.
Researchers argue that hepatitis B treatment should be expanded to include more people, as current drugs are safe and effective in slowing disease progression and reducing transmission. By treating more people earlier, the net disease and death rate can be significantly reduced.
Researchers at Sanford Burnham Prebys found that blocking macropinocytosis reshapes the tumor microenvironment, allowing more access to immune cells. This change made immunotherapy and chemotherapy more effective in treating PDAC tumors in mice.
Standard perovskite solar cells perform well during summer months but decline in efficiency during darker periods. Small-scale perovskite cells can achieve up to 26.95% efficiency under standard conditions.
Researchers have developed a novel polymer nanocomposite from COVID-19 waste masks, achieving record-high thermal conductivity and electromagnetic shielding. The closed-loop upcycling strategy reduces environmental impact and cost, paving the way for sustainable electronics and circular economy applications.
Research at University of Arizona Health Sciences found PFAS exposure affects gene activity, tied to cancers, neurological disorders, and autoimmune conditions. Changes in miRNA activity indicate potential health risks, suggesting a link between environmental exposures and disease.
Researchers used satellite data and AI methods to assess industrial fishing activity in MPAs, finding that strongly protected areas had significantly less fishing activity than surrounding waters. In some cases, no vessels were detected at all.
Diana Hargreaves will receive $1 million to advance her project on improving immunotherapy in patients with pancreatic cancer. Her previous work identified better drug targets for cancers with SWI/SNF mutations, leading to breakthroughs in treating difficult-to-treat cancers.
Researchers found that metastable epialleles in mice, which determine gene expression through DNA methylation, are remarkably scarce. In contrast to earlier studies, the study revealed that maternal diet had no effect on these epialleles, challenging previous findings.
A groundbreaking study found significant mitochondrial cardiolipin dysregulation in patients with bortezomib-induced peripheral neuropathy. The researchers identified diosmin as a promising candidate for targeting this condition, providing new avenues for therapeutic intervention.
Coral reefs face severe threats from climate change and heat stress. Researchers are turning to assisted gene flow (AGF) to restore genetic diversity and boost resilience. International collaboration and revisions to conservation laws are necessary to proactively expand AGF efforts, safeguarding and restoring coral reef ecosystems.
Researchers used IntelliCage to assess spontaneous behavioral changes in a mouse model of schizophrenia, finding increased hyperactivity and exploratory behavior after treatment with MK-801. However, cognitive flexibility was impaired, suggesting schizophrenia-like behaviors.
Researchers from the University of Illinois have demonstrated a viable and high-performance modular architecture for superconducting quantum processors. Their work enables system scalability, hardware upgrades, and tolerance to variability, making it an attractive option for building system networks.
A new study by Mass General Brigham found that over 35% of responses from large language models contained stigmatizing language related to alcohol- and substance use-related conditions. However, targeted prompts can reduce this language substantially. The authors recommend using patient-centered language to build trust with patients.
A new robotic slip-prevention method has been developed to improve robots' grip and handling of fragile or slippery objects. This bio-inspired approach allows robots to predict when an object might slip and adapt their movements in real-time, outperforming traditional strategies.
Researchers from NUS develop non-alternant carbon nanobelts featuring five-membered cyclopentadienyl units, allowing for improved electron flow and new electronic properties. The novel structures emit bright red light and exhibit small energy gaps, making them suitable for organic light-emitting diodes and solar cells.
A study published in PLOS One found that AI-generated music triggered greater physiological responses and was perceived as more emotionally stimulating compared to human-created music. The complexity of the prompt used also affected the impact of the music, with more complex prompts causing higher cognitive loads.
A new study identified seven immune-related genes downregulated in hepatocellular carcinoma and intrahepatic cholangiocarcinoma, which are associated with immune surveillance and complement pathways. The findings also revealed macrophage migration inhibitory factor signaling as a critical communication channel in ICC.
The TherVacB vaccine aims to activate the natural immune response to eliminate the hepatitis B virus. In a new phase 1b/2a clinical trial, 81 patients will receive increasing doses of the vaccine components to determine its safety and effectiveness.
Hospital and nursing home food are found to be lacking in healthy plant-based options, with too many refined grains, added sugars, and saturated fats. The study recommends reducing animal-source foods and increasing plant-based options to improve both human and planetary health.
The team aims to deliver AI power directly to devices, improving resilience and speed in constrained environments. By processing data step-by-step across a network of devices, they can create a safe and adaptable system that can withstand attacks and extreme conditions.
BASILISK, a global esports organization for science, partners with CalTech's IQIM and The Planetary Society to amplify science advocacy. BASILISK's players introduce respected scientific institutions to over 3.5 million gamers, expanding science outreach.
Researchers create AI model called UNITE that detects fakes by analyzing faces and backgrounds, making it one of the first tools capable of identifying synthetic or doctored videos. The system can flag a range of forgeries, from simple facial swaps to complex fully synthetic videos.
A national study found that healthcare providers exhibit varying levels of stigma towards patients with substance use disorders (SUD), particularly for opioid and stimulant use. This stigma leads to missed opportunities for care and is often embedded in clinical encounters.
Researchers found that protein structures are more like Lego than Jenga, with only a few critical amino acids in the core. A machine-learning algorithm created a tool to predict protein stability, potentially speeding up the development of new medicines and enzymes.
Researchers create metasurfaces to control photons and entangle them for quantum computing and sensing. The discovery could lead to miniaturized optical setups with improved stability, robustness, and cost-effectiveness.
A new case report describes the use of extracorporeal blood filtration to treat stage IV poorly differentiated pancreatic adenocarcinoma. The patient experienced clinical improvement, reduced pain, and no signs of new tumor growth over 12 months of follow-up.
The 2023 marine heatwaves were the most intense and persistent in recorded history, with temperatures reaching 96% of the global ocean surface. Regional drivers, including increased solar radiation and weakened winds, contributed to their formation and persistence.
A team of researchers led by Simona Stäger identified IRF-5 as a guardian of T cell metabolism and mitochondrial function. The discovery provides new strategies for boosting immunity to chronic infections or cancers, where T cell exhaustion is observed. IRF-5's role in preserving immune cell energy could play a key role in this approach.
The American Heart Association trained Duke student-athletes in Hands-Only CPR to equip them with the knowledge and confidence to act in emergencies. Nearly 9 out of 10 people who experience cardiac arrest outside a hospital die due to lack of immediate CPR, highlighting the importance of this skill.
Researchers use AI to solve differential equations, such as Schrodinger's equation, for large-scale systems, improving efficiency and accuracy in fields like drug discovery and material design.
A team at HZB used 3D X-ray tomography to create a digital copy of a Mongolian scroll, then virtually unrolled it using mathematical methods, revealing the scripture and ink traces. The scrolls contained Tibetan script in Sanskrit language and traditional Chinese ink with metal particles.
Researchers at Fox Chase Cancer Center have provided a detailed assessment of how fast breast cancers grow in patients and how surgical delays may affect breast cancer staging. The study found that upstaging rates associated with delays are relatively small and consistent with prior data.
A recent study detected titanium dioxide particles in 100% of animal milk samples and 83% of infant formulas, revealing widespread contamination. The findings suggest that infants' exposure to these particles does not end at birth, raising concerns over human and animal health.
Researchers analyzed 96 years of forest census data, revealing homogenization trends and loss of tree species. The study suggests that reduced forest diversity makes the ecosystem less resilient to future disturbances.
Researchers found that oxidative stress actually suppressed cancer development in rats with BRCA2 gene mutations, contrary to prior expectations. This discovery suggests that avoiding radiation exposure may not be the best method for people with BRCA2 pathological variants.
Research analysis of over 29 million people reveals a positive association between three types of air pollutant and dementia. The study found that long-term exposure to PM2.5, NO2, and soot increases the relative risk of dementia by 17%, 3% and 13%, respectively.