Cancer researchers at University of Cincinnati Cancer Center are exploring a new method called lattice therapy, which delivers higher doses to tumors and lower doses to surrounding tissues. The approach has shown promise in reducing treatment time and improving patient outcomes for head and neck, lung, and brain tumors.
A University of Cincinnati study found that exposure to PFAS may delay the onset of puberty in girls by an average of five or six months. The researchers also discovered decreased hormone levels consistent with the delay, raising concerns about negative long-term health outcomes such as breast cancer and renal disease.
A recent study by University of Cincinnati researchers found that a community-wide naloxone distribution program did not significantly reduce opioid overdose deaths. The study, which ran from 2017 to 2019, saw no significant change in median monthly opioid overdose rates despite widespread availability of the medication.
A new study from the University of Cincinnati explores the molecular mechanism of psychological loss through enrichment removal, identifying a key area of the brain that plays a role in this experience. The research highlights the importance of understanding how loss affects mental health and may lead to novel therapeutic targets.
A team of UC researchers, led by Ashley Kubley, have received a $2.5 million state grant to continue research on improving firefighter protective gear. The project aims to develop a firefighter jacket liner that brings down body temperature through advanced cooling technology and protects against external hazards.
Experts convened at the Stroke Treatment Academic Industry Roundtable XII meeting to address key issues hindering enrollment in acute stroke trials. Broadening emergency consent procedures and adopting efficient trial designs are recommended to enhance participant recruitment.
A recent study published in JAMA found that lowering blood pressure after mechanical clot removal may not be safe or effective among patients with acute ischemic stroke. Researchers recommend allowing blood pressure to auto-regulate after endovascular treatment, but individualized approach may be necessary for specific conditions.
Researchers at the University of Cincinnati have developed a new at-home test that uses saliva to detect early signs of gingivitis, the earliest form of gum disease. The device can identify periodontal disease caused by bacteria in saliva, providing an opportunity for consumers to protect their oral health.
A new battery design without a membrane has been developed by researchers at the University of Cincinnati, offering higher energy density and lower costs. The battery can generate nearly 4 volts of power, eliminating costly and inefficient membrane-separators.
A study by UC professor Gary Painter found that rent-burdened households in Los Angeles face significant trade-offs, including cuts to healthcare, education, and entertainment. The survey, conducted in 2019, revealed that nearly 85% of respondents made consumption cutbacks to make life more affordable.
A new study published in International Journal of Radiation Oncology, Biology, Physics found that multiple beams and intervals in delivery during FLASH proton therapy treatment reduced skin-saving effects in preclinical models.
A UC economist found a strong correlation between park funding and home values in Ohio communities. House prices were 13% higher three years after voting to renew tax levies for recreational areas, but not immediately after the vote. The study suggests that underfunded parks may be a contributing factor to lower housing values.
The Dasypeltis gansi, a harmless African snake, consumes eggs whole and can eat prey three to four times bigger than black rat snakes. This unique adaptation allows it to outeat Burmese pythons relative to its size.
UC researchers investigate signaling pathway of Trypanosoma cruzi to transform and reproduce, aiming to find better drug targets to kill the parasite. The study reveals crucial proteins involved in the parasite's survival and transmission, highlighting potential strategies for disease control.
A new imaging method developed by UC researchers can identify specific lung infections in real time, reducing diagnosis time from 2-3 days to hours. The method uses injectable probes that light up under a nuclear imaging machine, enabling faster treatment for critically ill patients.
A federally funded study led by University of Cincinnati clinical psychologist Sarah Whitton aims to identify mental health risks and protective factors for sexual minority women. The FAB400 cohort, a racially diverse group of nearly 400 women aged 21-26, will participate in an additional six waves of data collection over 2.5 years.
A team of researchers used genetic and isotopic analyses to study jaguar scat in the Mountain Pine Ridge Forest Preserve, revealing habitat needs and conservation insights. The study demonstrates a novel approach to surveying wildlife without direct interaction.
Research suggests that forests played a crucial role on the island before people changed the landscape to grow crops and graze domesticated animals. The study found that hippo isotopes indicate they did not regularly graze in open habitats, but instead fed on sedges and leaves.
Researchers at the University of Cincinnati have discovered two existing drugs that show signs of being effective in treating lymphangioleiomyomatosis (LAM), a rare and devastating lung disease. The study found that these drugs target a novel pathway dysregulated in LAM, which could lead to the development of a cure.
A new study highlights disparities in access to digital technology, leading to fewer health care options for rural communities. The study found that socially vulnerable communities face barriers to adequate health care and have less access to high-speed internet.
Researchers found increased levels of TMAO in abdominal aortic aneurysm (AAA) patients, which led to disease progression. Inhibiting TMAO production reduced aneurysm severity, suggesting a potential therapeutic target.
Researchers developed a new probe to measure pH levels in cells, revealing a constant conversion rate from endosomes to lysosomes. The probe's ability to track pH changes enables faster diagnosis and potential treatments for lysosomal diseases.
A multi-institutional phase 3 clinical trial found that a cancer stem cell test can accurately decide more effective treatments and lead to increased survival for patients with recurrent glioblastoma. ChemoID, a CLIA-accredited diagnostic test, was used to select chemotherapy treatments, resulting in significantly lower risk of death a...
A pilot program, developed by University of Cincinnati anthropologist Kathleen Grogan, invited postdoctoral researchers to review each other's job application packages, providing critiques and psychosocial support. Most participants found the feedback helpful in improving their chances of securing a faculty position.
A study published in Clinical Pharmacology & Therapeutics has identified six single nucleotide polymorphisms associated with opioid use disorder. The findings suggest that genetics play a role in the development of OUD, but environmental factors also contribute to its progression.
Neurologist Soma Sengupta introduces the concept of integrative neuro-oncology, combining conventional treatments with alternative therapies to enhance patient well-being. Her approach prioritizes the unique needs of brain tumor patients and their caregivers, promoting a holistic understanding of medicine.
The study found associations between prenatal maternal stress life events and adverse neurodevelopmental outcomes in offspring. DNA methylation likely plays a role in these associations. The research provides new insights into how the fetal environment influences neurodevelopment, metabolism and immunologic functions.
Biologists found that underfed jumping spiders lose photoreceptors, key to their vision. The study suggests nutrition affects retinal and neuronal health, potentially leading to breakthroughs in treating macular degeneration.
A research team led by the University of Cincinnati's Atsuo Sasaki aims to understand how an enzyme regulates lysosomal function based on energy molecule GTP. This study could lead to new treatments for cancer, neurodegenerative diseases and anti-aging.
New research suggests the Marinoan Ice Age, which created glaciers from pole to pole 635 million years ago, had patches of open water in mid-latitude seas. This finding provides evidence that life could have persisted during this period, potentially influencing the carbon cycle and climate.
Researchers found that low-impact development practices, such as permeable pavement and bioretention cells, are effective in reducing flood risk in residential areas. Detention basins are also a viable option for areas with high impervious surfaces.
Researchers found that monk parakeets lose their social standing after a brief absence, particularly among high-ranking birds. The study, led by Annemarie van der Marel, used networks of aggression and observational studies to quantify bird status in dominance hierarchies.
A study published in the journal Cancer found that long-term pancreatic cancer survivors have a robust immune response and enriched gut microbiome species, including Faecalibacterium prausnitzii. The research suggests that these bacterial species may promote immune response to pancreas cancer.
Researchers found that corridors with abundant mature trees and deadwood help pileated woodpeckers adjust to urban landscape fragmentation. The Little Miami River corridor is one of the best places for these birds in Hamilton County, Ohio.
A new UC study reveals that participating in a civic leadership program empowered refugees and immigrants, increasing their perception of civic engagement. The program, designed by the refugee community, improved participants' consciousness about power, rights, and opportunities.
Researchers found that dexamethasone prevents cytokine storms in severe COVID-19 patients by inhibiting ion channels and reducing immune cell inflammation. This led to improved lung function and reduced mortality rates. The study's findings provide new insights into the mechanisms of steroid treatment in severe COVID-19.
Scientists have engineered a unique strain of probiotic bacteria to over-express a metal transporter that binds and concentrates copper, facilitating the delivery of radionuclide therapy to cancer cells. This approach targets tumors without relying on specific receptors, making it potentially effective against treatment-resistant cancers.
A new study highlights digital divide disparities in rural US communities, citing limited broadband and lower socioeconomic resources. Researchers stress the need for targeted policies to increase access to telemedicine and online health services.
Researchers in Japan used a synchrotron to create gamma rays that revealed unusual fluctuations in the electrical charge of a strange metal alloy. The study provides insight into the inner machinery of these materials, which could inspire new forms of electronic matter and high-temperature superconductivity.
Researchers at the University of Cincinnati developed an innovative breathing device called PEP Buddy, which improves symptoms of breathlessness, quality of life, and oxygen levels in people with COPD. The study found significant reductions in shortness of breath and improvements in quality of life among participants.
A recent study published in JAMA Network Open found that the US government allocates very little federal funding for research on incarceration from a public health standpoint. The lack of funding is attributed to structural racism, business interests, and a lack of awareness among healthcare professionals.
Researchers found that no single helmet design consistently reduced concussion incidence, with the back of the helmet showing vulnerabilities. The study suggests combining lab tests with field-based impact tracking could provide better protection for athletes.
Researchers found that psychedelics combined with talk therapy can help people see themselves as nonsmokers, leading to a higher success rate in quitting smoking. The study suggests that psychedelics can reshape self-perceptions to help break free from old habits and addictions.
Researchers found that female caribou shed their antlers within days of giving birth, leaving behind a record of their annual travels across Alaska and Canada's Yukon. The study demonstrates how important the area is for an animal that native Alaskans and Canadians still depend on for sustenance.
The NCI is funding a $587,000 research grant to improve KRAS treatment resistance in pancreatic cancer. Dr. Andrew Waters aims to develop personalized medicine approaches by studying unique resistance mechanisms.
Researchers found a unique, silent frog species in Tanzania's Ukaguru Mountains, highlighting the importance of conservation and understanding diverse ecosystems. The discovery provides critical information for protecting this critically endangered species and its habitat.
Biomedical engineers at the University of Cincinnati are investigating the potential of interstitial fluid for early disease diagnosis and long-term health monitoring. The study proposes sampling interstitial fluid just under the skin using tiny microneedles, offering a more accessible and less painful alternative to blood testing.
A study published in PLOS ONE found that wearing tefillin, a traditional Jewish practice, can induce preconditioning associated changes in heart rate variability, leading to lower metabolism and potential protection against heart attacks. The research suggests this low-intensity method of protection could be a game changer for cardiova...
A multidisciplinary team of UC students developed a new understanding of spinal column formation and reengineered the process in mutant zebrafish. This breakthrough could lead to possible treatments for scoliosis in humans.
Researchers are working to understand the events contributing to pancreatic cancer development by studying gene abnormalities and their effects on the disease. Dr. Krushna Patra's lab is focused on understanding how genetic mutations like GNAS contribute to pancreatic cancer growth.