An international team of scientists has detected a quasi-periodic oscillation (QPO) signal in the radio band from a Galactic black hole system, revealing features that have never been seen before. The QPO signal may provide the first evidence of activity from a jet launched by a Galactic stellar-mass black hole.
Researchers developed a new method for capturing turbulent flame behavior, providing detailed insights into flame dynamics, ignition processes and combustion efficiency. The high-speed 3D imaging approach can be used to optimize energy production processes and improve fire safety measures.
A first-in-human study demonstrates the efficacy of a novel PRMT5 inhibitor, JNJ-64619178, in treating advanced solid tumors. The treatment showed manageable dose-dependent toxicity and achieved preliminary antitumor activity in patients with various cancer types.
A team of scientists has developed an optically transparent terahertz cavity to manipulate phonon vibrations in semiconducting perovskites. This design allows for on-demand adjustment of ultrafast THz field modulation, benefiting photonic integrated devices and optical communications.
A new study shows that earlier transfer to specialized care is associated with better outcomes for infants with NOWS, including shorter hospital stays and less exposure to medication. The study found that nonpharmacologic interventions, such as swaddling and pacifier use, are critical to clinical outcomes.
A new study finds that climate change poses a significant threat to all listed plant and lichen species, with only a minority of conservation plans taking direct action to address this issue. The researchers urge policymakers to use their findings to inform conservation planning and recovery efforts for these endangered species.
A Washington State University study found that popular health-related videos on TikTok primarily cover sexual health, diet, and exercise topics. Influencer role models and aesthetic details dominate the content, lacking attainable behavior change advice.
An observational study of college students found that young women are more likely to engage in risky behaviors like multitasking and conversation while descending stairs. This is compared to young men who were less likely to engage in these behaviors, suggesting that women may be more distracted while descending stairs.
Researchers found fungi can effectively degrade low-density polyethylene (LDPE) plastic without wood present. In the absence of wood, fungal biodeterioration of LDPE increased, suggesting a potential natural method for plastic waste management.
Researchers found that CAR NK cells lose metabolic fitness when competing with tumor cells for nutrients, leading to resistance. Engineering cells with IL-15 enhances metabolic fitness and provides a longer-lasting anti-tumor response.
Researchers developed an atactic C1 polymer with a high melting point by incorporating amide-linkages into its side-chain. The dense-packing of its side chains enhances hydrogen-bonding interactions, resulting in a higher melting point of up to 130°C.
Researchers have uncovered a novel mechanism of cell death regulation, shedding light on its significance during conditions such as SARS-CoV infection and skin injury. The study reveals that the cleavage of cFLIP restrains cell death during viral infection and tissue injury, favoring tissue repair.
Under warming temperatures, lizards may skip over potential mates to quickly choose a partner. Researchers found this behavior in a social lizard species due to environmental changes.
The BMJ investigation found that pharmaceutical companies contributed £7.5 million to royal colleges between 2015-2022, mainly for events and grants. Critics argue that voluntary industry transparency initiatives do not go far enough and do not guarantee full disclosure.
A new study found that individuals vaccinated with the newer pertussis vaccine show similar immune responses to antigens present and absent from the vaccine, suggesting that asymptomatic infections drive T cell response. This could lead to the spread of the bacteria to vulnerable populations.
A UCLA Health study found that Kundalini yoga increased activity in a region of the brain impacted by stress and associated with memory decline. The study suggests that this type of yoga, which combines movement and meditation, may be beneficial for older women at risk for Alzheimer's disease.
Researchers found no directional change in Arctic spring timing over the past 25 years, instead observing extreme year-to-year variation due to climate variability. This shift is attributed to fluctuating temperatures and snow cover, pushing species to their limits.
Research reveals a significant cross-seasonal connection between Arctic sea ice and Eurasian summertime temperature fluctuations. The study found that changes in Arctic sea ice influence atmospheric waves over the North Atlantic–Barents-Kara Sea–Central Asia regions, leading to corresponding changes in temperature fluctuations.
Researchers at California Polytechnic State University have developed a novel method for storing biological materials such as RNA and proteins in a solid-state, resembling a pill or tablet that dissolves in water for on-demand use. This innovation overcomes current limitations in storage and handling, making it easier to access these m...
Researchers have confirmed that honeypot ant honey possesses unique antimicrobial characteristics, effective against Staphylococcus aureus and two species of fungi. The study marks the first time ant honey has been investigated for its medicinal properties.
The article explores how export diversification and ICT shape employment patterns, with research highlighting the importance of diversified trade baskets to minimize economic uncertainties. Tailored trade policies can unlock employment opportunities for both high-skilled and low-skilled workers, fostering sustainable growth.
A new study published in Interface found that casein, a protein found in cow's milk, significantly improved wound healing in rats compared to control groups. The promising results suggest that casein could replace expensive materials like silver in wound dressings.
A new study using ancient DNA found that workers buried more than 500 years ago came from different parts of the Inca Empire, including Amazonia. The analysis supports historical documentation and archaeological studies, providing insights into the genetic histories and lifeways of Machu Picchu's occupants.
Research found that very light exercise can improve prefrontal executive function, with pupil dilation during exercise indicating subsequent improvement. Pupil-linked neural activity was also shown to activate the brain's noradrenergic arousal system.
The study developed a new synthetic method for homoHPHACs and synthesized a series of compounds with electron-donating to electron-accepting substituents. Substituent effects on structural, optical, redox, and antiaromatic properties were demonstrated, with electron-accepting substituents showing strongest anti-aromatic and aromatic pr...
A study by researchers at the University of Texas at Austin found that institutional investors demand disclosure of climate risk due to its impact on a company's health and performance. The survey of 439 institutional investors showed that mandatory disclosure has an effect on investors' decisions.
Researchers reconstruct two massive family trees from ancient DNA data, shedding light on the lives of a prehistoric European Neolithic community. The study reveals a strong patrilineal pattern, large family sizes, and a potentially fluid exchange network comprising many groups.
Researchers surveyed primary care clinicians on telemedicine use during the pandemic, noting initial challenges but increasingly positive attitudes towards its value. Clinicians recognized video- and phone-based care as a valuable tool, but also identified obstacles such as infrastructure and reimbursement issues.
Scientists studied 470 sera from vaccinated or MPXV-infected individuals to elucidate mechanisms involved in post-infectious immune response. The study revealed the role of complement and analyzed immune responses in vaccinated or infected individuals, with robust levels of anti-MVA antibodies detected after infection or vaccination.
A team of UCI researchers identified a distinct class of brain inhibitory neurons that may contribute to neuropsychiatric conditions. These neurons, characterized by parvalbumin and cholecystokinin expression, play a crucial role in regulating brain activity.
A nationwide Finnish study found that premature parental death is strongly linked to poor mental health and lower earnings in adulthood for both sexes. Boys are more vulnerable than girls, with nearly twice the odds of hospital admission for intentional self-harm after losing their mother prematurely.
Dr. Amir Asadi's team embeds patterned nanostructures into high-performance composites to achieve multifunctionality and structural integrity simultaneously. This approach offers a practical and scalable method for creating nanostructured materials with tunable properties, revolutionizing the manufacturing of high-performance composites.
A Kenya-based study found that menstrual cups reduced the risk of bacterial vaginosis and improved vaginal microbiome in teenage girls. The study, funded by the National Institutes of Health, followed 436 Kenyan secondary school girls and tested for infections every six months.
A recent study from the University of Cambridge and King's College London found that over half of patients with autoimmune conditions experience mental health symptoms, but are rarely or never asked about in clinic. The study highlighted a significant gap in mental health support for these patients.
A recent journal article by University of Miami researchers outlines ways to achieve greater equity in ocean governance and science in the global tropics. The authors emphasize the need to give a voice to the 'tropical majority' and incorporate indigenous knowledge into ocean management.
Researchers at North Carolina State University have developed a new robot called RoboMapper that can conduct experiments more efficiently and sustainably to develop new semiconductor materials. The robot automates the process of testing multiple samples simultaneously, reducing time and energy consumption by nearly 10 times.
A study suggests that bare minimum reimbursement rates could be a barrier to HPV vaccination, with non-pediatric specialties receiving lower rates. Family medicine doctors were found to be most sensitive to changes in reimbursement, which may contribute to geographic disparities in vaccination rates.
Researchers analyzed 1.8 million aircraft operations and 460,000 sUAS flights to identify 24 near-midair collisions. The study suggests extending runway exclusion zones for drones at high-risk airports to improve safety.
The study, published in Advanced Functional Materials, reveals a novel light-activated material that can be used to effectively reshape and thicken damaged corneal tissue, promoting healing and recovery for patients with keratoconus. The technology has tremendous potential to impact millions of people suffering from corneal diseases.
Researchers have developed a new class of molecules that form a molecular highway for electrons, eliminating charge trapping and improving the efficiency of blue OLEDs. This design simplifies the production of high-efficiency blue light-emitting diodes.
Researchers have made significant breakthroughs in high-speed photonic sources using metal-halide perovskites, promising to increase bandwidths into the gigahertz levels. The technology has vast potential for future data communication, IoT devices, and other emerging services.
Researchers have developed a novel DNA-filtering system using α-hemolysin nanopores to reduce contamination in single-molecule DNA extraction. The technique, which uses phospholipids and the PCR clamp method, achieved a 99.98% reduction in DNA contamination.
Scientists found that contemporary fires in dry conifer forests are burning hotter and killing more trees than in previous centuries, due to a lack of low-severity fires. Regular management and prescribed fires can help mitigate this trend and restore resilience to these ecosystems.
Researchers discovered δ-FAPbI3 as a promising material for X-ray detection due to its high ion mobility barriers, low Young's modulus, and exceptional long-term stability. This enables the creation of ultra-stable imaging applications with high sensitivity and low detection limits.
A new underwater mass spectrometer has successfully completed sea trials to detect dissolved gases in the deep sea, with long-term detection capabilities reaching 25.8 hours. The technology paves the way for research on global climate change and the origin of life.
Researchers at the University of Virginia Health System discovered that improper calcium signaling in mitochondria accelerates chronic inflammation, leading to age-related conditions. Increasing calcium uptake in macrophages may help prevent harmful inflammation and its effects on the brain.
Researchers from Tokyo Institute of Technology have successfully synthesized high-purity SrVO2.4H0.6 and Sr3V2O62H0.8 perovskite oxyhydrides using a novel high-pressure flux method, opening up new possibilities for catalysts and lithium-ion battery electrodes.
Researchers identified key strategies contributing to significant reductions in Medicare acute hospitalization rates at high-performing Comprehensive Primary Care Plus (CPC+) sites. These clinics implemented effective strategies such as improving timely access to primary care, identifying high-risk patients with enhanced care managemen...
A study by the University of Essex found that top performers had a specific combination of 19 gene variants linked to running performance, resulting in an average improvement of 11.5% after just eight weeks of endurance training. Despite having the same training, those without these genetic markers showed little or no improvement.
A preclinical study found that the drug ADX106772 reduced oxycodone intake and relapse in animal models of opioid use disorder without disrupting other reward responses. The therapeutic was tested in rats trained to self-administer oxycodone and showed significant reduction in oxycodone intake for up to 12 hours.
Metalenses have been developed with differentiated design principles to eliminate chromatic aberration. By merging bright spots into a single focusing spot, researchers achieved an efficiency of up to 43% and demonstrated the versatility of their approach for various optical applications.
A pooled data analysis of clinical trials found that static isometric exercises were the most effective in lowering blood pressure, with reductions of up to 8.24/4 mmHg after isometric training. The findings suggest that current exercise guidelines may be outdated and support the development of new recommendations.
Researchers examined core elements shared between human intelligence and AGI, focusing on scale, multimodality, alignment, and reasoning. They found that brain-inspired AI systems can mimic human-like rapid learning capabilities through large language models.
A multidisciplinary team of scientists has revealed the existence of a brain circuit involved in sensing and regulating inflammation. The circuit detects inflammatory hormones in the blood and organizes the immune response through the vagal complex and parabrachial nucleus.
Researchers found that fork-tailed drongos use unique egg 'signatures' to identify cuckoo eggs, rejecting 93.7% of 'forgeries'. This defence mechanism may help explain why African cuckoos remain common in Africa despite high mortality rates among young birds.
Researchers discovered primary cilia play a crucial role in self-healing mechanisms after growth plate fractures. The Hedgehog signaling pathway and Smoothened agonist activation accelerate cartilage repair.
A new study found that babies with food allergies are more likely to develop asthma and have reduced lung function by six years of age. Early life food allergy was associated with an increased risk of both conditions, even if the allergy resolved or persisted.
A recent study in Japan found that consumer awareness of bioplastic characteristics is limited, with most respondents unaware that not all bioplastics are biodegradable. Educational interventions can increase willingness to pay for more environmentally friendly products, particularly those reducing CO2 emissions.
A new clinical practice resource provides valuable information for healthcare professionals caring for individuals with pathogenic variants in the CHEK2 gene. The resource assesses personalized risk estimates based on family history, specific variant, and other factors.
A study by Dana-Farber Cancer Institute researchers found that gliomas can arise from epigenetic changes, which affect gene activity without altering DNA sequence. The findings pinpoint two genes, an oncogene and a tumor suppressor, whose activities are epigenetically altered in human gliomas.