Researchers study DNA minicircles using hydrodynamic measurements to understand their behavior under twisting, revealing unique shapes and compactness. The investigation combines theoretical approaches with experimental methods to elucidate dynamic hydroelastic effects in DNA.
A novel, low-cost sensor system utilizing force-sensing resistor technology has been developed by Pusan National University researchers for real-time pipeline monitoring. The system demonstrated a 99.4% correlation with commercial sensors, enabling accurate detection of pipeline damages.
Researchers found that seed systems are often disrupted by conflict, social inequality, and poor policies. Emerging initiatives like participatory plant breeding help farmers secure food supplies by developing crop varieties tailored to their needs.
Researchers analyzed human mortality data from 19 countries and found no evidence of a maximum lifespan being approached. The study suggests that while mortality rates increase with age, the rate of death doesn't reach a plateau or maximum limit.
Researchers from Spain, Italy and Norway uncover a cluster of water channel genes in teleosts that allow eggs to float. The study reveals unique mechanisms for hydrating maturing eggs, which determines their buoyancy.
A team of scientists at Memorial Sloan Kettering Cancer Center identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors. Drugs that activate STING could help prevent the spread of cancer to new sites, a process known as metastasis.
Researchers developed a model to track COVID-19 data, predicting transmission and informing health surveillance systems. The model successfully predicted the spread of COVID-19 in Cali, Colombia, highlighting the importance of high-resolution data in understanding virus dynamics.
Researchers found that receipt of opioid use disorder-related telehealth services was associated with reduced risk for fatal drug overdoses. Additionally, medication from opioid treatment programs and buprenorphine in office-based settings also showed a protective effect.
A recent UBC study reveals that the planet's biomass is disproportionately distributed among tiny and massive organisms, with no clear explanation for this pattern. The findings have significant implications for understanding climate change impacts and ecosystems.
A new generation of head-mounted microscopes has been developed to record neuronal activity in freely-moving mice, allowing researchers to study complex behaviors and behaviors. The device offers a field of view four times larger than previous designs, while weighing just 1.4 grams.
Scientists have discovered a new topological phase in twisted 2D materials, which could lead to breakthroughs in nanotechnology. The discovery reveals the formation of polar domains that are inherently topological and form objects known as merons and antimerons.
Researchers at the University of Missouri have developed a process for marking transplanted donor bone marrow cells, allowing them to target only cancerous cells. This breakthrough offers new hope for bone marrow transplant patients with blood cancers such as lymphoma and leukemia.
A recent experiment at Jefferson Lab has revealed the radius of the proton's mass generated by gluons, which may have shed light on the origin of its mass. The result indicates that this core has a different size than the proton's well-measured charge radius.
Scientists have mapped the complete trajectory of placental development, shedding light on why pregnancy disorders occur. The study reveals new information on cell communication and trophoblast development, providing a better understanding of the process.
Researchers identified a crucial molecular process involving gene expression in neurons that contributes to early memory loss and Alzheimer's disease. Genetic alterations in mice showed that lack of phosphorylation on beta-2 adrenergic receptors led to poor memory, while PDE inhibitors improved memory function.
Researchers used explainable AI to analyze gut microbiomes for CRC biomarkers, discovering four distinct subgroups with unique bacterial profiles. This approach shows promise for a more personalized microbiome exploration and potential disease subgroup identification.
A meta-analysis found strong links between cluster headache and migraine and the circadian system, with specific patterns of attacks and hormonal associations. The study suggests using circadian-based treatments as a potential new approach for headache disorders.
A global study analyzing height and BMI data from 71 million children and adolescents found that urban areas are no longer healthier than rural areas, especially in sub-Saharan Africa. Rural areas have been closing the gap in recent decades due to improvements in nutrition and healthcare.
A research group at Nagoya University discovered that the Japanese longicorn beetle has a symbiotic yeast called Scheffersomyces insectosa. The yeast breaks down xylose and other wood components, making it edible for the beetles.
Researchers at NIST have developed a new method of digitally simulating hurricanes using AI techniques, accurately representing the trajectory and wind speeds of real storms. The simulations can help develop improved guidelines for building design in hurricane-prone regions.
An international project aims to discover modifiable cellular and molecular pathways of the developing infant immune system to improve infant vaccine responsiveness and prevent respiratory disease. By analyzing infants' immune systems from birth to five years old, researchers hope to identify biomarkers that predict vaccine responsiven...
Researchers found that SARS-CoV-2 infection causes drastic changes to RNA modifications, including the loss of m6A modification. This disruption may lead to persistent COVID-like symptoms and provide a new potential drug target against COVID-19. The study's results could also shed light on chronic post-COVID conditions.
Researchers have developed RGO-MXene membranes that exhibit high pure water permeance and improved electro-enhanced rejection performance. The membranes' wettability-regulated channels enhance water entry rates and boost rejection rates for charged species under electro-assistance.
A new class of compounds reduces weight dramatically and lowers blood glucose in lab animals, boosting calorie burn and avoiding nausea. The injectable treatments activate multiple gut hormone receptors, including GLP-1 and PYY, to signal fullness and curb appetite.
A new study from the University of Delaware refutes criticism that DACA policy hurts jobs and income, finding it may actually improve the economic climate. The study, led by Emily Battaglia, analyzed data from 2005 to 2018 and found no negative impact on native-born Americans or non-eligible immigrants.
Researchers developed a novel enrichment strategy to build a Tetrasphaera-enriched EBPR microbiome, which showed enhanced nutrient removal and increased P recovery. Allylthiourea was found to be the key abiotic factor for Tetrasphaera-rich microbiome establishment.
Researchers at NTNU developed a new test to measure flow state, which can be useful for teachers to adapt instruction. The General Flow Proneness Scale has been shown to be reliable and valid, with good results from 228 participants.
Researchers found that cells in the colon undergo a type of molecular time travel, reverting back to an embryonic state and creating immature, non-functional cells that can form benign growths called adenomas. Blocking Sox9 in mouse models prevented adenoma formation and resulted in mature cell maturation.
A new PET/CT scanner prototype has shown promising results in preclinical testing, offering higher resolution and accurate tumor assessment. The scanner aims to enhance treatment planning for head and neck cancers, which have a low five-year survival rate and high recurrence rate.
Children born to mothers infected with COVID-19 during pregnancy may experience altered growth patterns and increased weight gain in early life, which can lead to a higher risk of obesity, diabetes, and cardiovascular disease. The study highlights the importance of long-term follow-up and prevention strategies for pregnant individuals.
A new condition, Caesarean Scar Disorder (CSDi), has been defined by an international study led by Amsterdam UMC. More than 30% of women who undergo a caesarean section experience long-term symptoms like abdominal pain and fertility problems, caused by abnormal uterine scars.
Researchers have discovered that medieval Swahili people had both African and Asian ancestry, with DNA analysis revealing relationships between Asian merchants and African traders in the 9th-11th centuries. This new research provides a genetic framework for understanding the cultural changes associated with the adoption of Islam.
EPFL researchers have discovered a way to store and process data using magnetic waves, potentially solving the issue of energy-hungry computing technology. This approach enables non-volatile storage within the same system, reducing the need for separate processors and memory storage.
A new AI tool analyzed food consumption data from over 600 residents in long-term care homes, revealing a need for improved dietary habits. The study suggests that a diet rich in whole grains, plant-based proteins, and plain fruits and vegetables can help reduce inflammation and improve clinical outcomes.
According to a recent study, most biological life falls within these two extreme sizes, with substantial uncertainty surrounding body size and biomass across different environments. The research suggests that this pattern may be due to various factors such as energy efficiency and adaptability.
Researchers at NUS developed a new synthesis strategy for highly efficient inorganic membranes, offering maximum energy efficiency and customization. These freestanding membranes have the potential to transform industries beyond filtration and separation, including energy conversion, catalysis, and sensing.
A study by UConn researchers found a significant improvement in shod horses, with better movement and reduced lameness scores. Shoeing with plain stamp shoes improved maximum hock angles and gait quality, indicating potential benefits for athletic performance.
Researchers at Osaka Metropolitan University discovered that whale shark rhodopsin can detect blue light, a common wavelength in the deep-sea environment. The unique adaptation allows the whale shark to thrive in low-temperature and low-light conditions, but also makes it less thermally stable.
The funding will support preclinical research using genetically modified pigs, aiming to improve compatibility and reduce immune rejection in xenotransplantation. The goal is to enable human clinical trials and address the organ shortage crisis.
A UCF research team, in partnership with the City of Orlando, aims to prevent falls among older adults through a low-cost, portable technology-based intervention. The project seeks to address public health disparities and support the development of affordable housing options.
Research shows that higher Body Mass Index (BMI) in the oldest old is associated with a range of health issues. The study also found significant differences between women and men in terms of mental health concerns related to BMI.
A large-scale study found that diagnostic errors in neuroradiology were associated with longer interpretation times and higher shift volumes. The study also revealed a significant increase in diagnostic errors during weekend work, highlighting the need for targeted quality improvement interventions.
Researchers at Georgia Institute of Technology developed a synthetic tumor model to understand the impact of microenvironment on targeted therapies for Activated B Cell-like Diffuse Large B cell lymphoma. The model showed promise in demonstrating how combining therapeutics can overcome tumor resistance to inhibitors.
A study found that honeybee hive debris contains diverse genetic information from environmental bacteria, fungi, and plants, indicating unique microbial signatures for each city. This could be used to assess the overall health of cities and honeybees.
A rapid genetic testing model identified pathogenic variants in 51 patients with advanced prostate cancer, leading to discussions of possible treatment changes for 22 patients. The streamlined approach detected actionable gene variants eligible for newer targeted therapies in nearly half of patients with these variants.
A new study led by UCL researchers found evidence of ancient empires' impact on migration in Africa, revealing genetic traces from across the continent. The study used DNA data from over 1,300 individuals from 150 ethnic groups, identifying migrations linked to empires like Kanem-Bornu and Aksum.
Recent studies using first-principles calculations and micromagnetic simulations have shown that chiral magnetic domain walls can coexist with the quantum anomalous Hall effect in specific materials, such as VSe2 and Fe2XI. This control enables precise manipulation of dissipationless chiral edge states.
Delattre is being recognized for his seminal genetic insights into the etiology of pediatric solid tumors, which have had substantial clinical implications. He has also been instrumental in identifying genetic alterations in other childhood cancers, including the BCOR-CCNB3 translocation.
The article provides 12 recommendations to enhance the quality of surveys, including transparency, clarity, and correcting the record. The recommendations aim to address challenges in survey research, such as biased responses and inaccurate forecasts.
A recent study found that polymeric PFAS used in food packaging break down into toxic smaller molecules, contaminating food and the environment. The research contradicts claims that polymeric PFAS are harmless and poses a risk to human health.
A new study reveals that the most endangered turtles and crocodiles are those with unique life strategies, which carry out critical processes in their ecosystems. The researchers highlight the urgent need for effective conservation management plans to protect these species and their habitats.
Research at IRB Barcelona reveals CPEB4's essential role in T lymphocytes' adaptation to chronic cellular stress. By overcoming this stress, these cells can exert their antitumour function and halt tumour growth.
A team led by Professor Yoshihiro Yamazaki from Kyushu University discovered the chemical innerworkings of a perovskite-based electrolyte developed for solid oxide fuel cells. By combining synchrotron radiation analysis, large-scale simulations, machine learning, and thermogravimetric analysis, they found that protons are introduced at...
Scientists from CSIC and UPV create modified ABA receptor activated by iSB09 molecule, increasing drought tolerance in plants. The combination efficiently activates the ABA pathway, triggering adaptive mechanisms and reducing water loss.
Researchers investigated life and death of a West Antarctica subglacial lake and found evidence for Caribbean plate subduction in southern Costa Rica. Additionally, studies examined oxygenation in Earth's oceans and explored the control of Cambrian paleotopography by Precambrian crustal-scale features.
A proactive patient education/recruitment program, administered with a nurse navigator, identified 37.3% more eligible patients for low-dose computed tomography (LDCT) screenings for lung cancer. The program led to a 42% increase in LDCT prescriptions among willing and eligible patients.
A team of paleontologists used the history of steam engines to test competitive exclusion theory, finding limited evidence supporting its role in extinction. The researchers analyzed data on tractive effort, revealing that newer engines generated more power, making steam locomotives less efficient and eventually obsolete.
Researchers found significant decreases in the levels of KRAS, RHOA, RAC1, and CDC42 after PCAI treatment, implicating their role in cancer progression and metastasis. These findings support the potential of PCAIs as potent agents for developing new anticancer therapeutics.
A new study by Florida Atlantic University suggests that monetary policy can impact pollution, with domestic effects being more significant than international spillovers. The research found that changes in the US Fed's interest rates can reduce CO2 emissions in the short run, but not necessarily in the long run.
Genetic welding proposes using CRISPR-Cas9 technology to rapidly change evolutionary courses in animals or plants. Cutting argues that this method requires scientific and ethical scrutiny before its application.