Climate models used to project climate change are not accurately reflecting the Arctic's future due to limited observations and calibration issues. The rate of warming will be much faster than projected, leading to a faster melt of sea ice.
Researchers have identified two novel genes, SRRM2 and AKAP11, linked to schizophrenia. The study suggests that rare damaging variants in these genes confer a similar magnitude of schizophrenia risk across diverse human populations. This finding has implications for the development of new treatments for the disease.
Researchers found an enzyme in liver cancer cells that can convert a group of compounds into anticancer drugs, killing cells and reducing disease in animals. The enzyme SULT1A1 activates compounds like YC-1, making them toxic to tumor cells.
A nationwide study found that financial disruption, such as a parent losing their job, was associated with increased stress, sadness, and COVID-19-related worry in children, but not sleep. School disruption had no association with mental health or sleep outcomes, surprising researchers.
Researchers have developed a novel and cost-effective anode catalyst that can improve and stabilize power generation performance of MFCs treating vegetable oil industry wastewater. The study investigates modification of electrodes to increase bacterial adhesion and efficient electron transfer.
Researchers have identified two potential molecular targets, CSF1R and CD86, that can be used to develop CAR-T cells effective against acute myeloid leukemia. The study's findings demonstrate the potential of AI-assisted analysis in discovering new treatment options.
A systematic review of 33 randomized controlled trials found that yoga improved gait speed and lower extremity strength in inactive older people. However, it did not offer a benefit for frailty markers compared to exercise or tai chi.
A report by Northumbria University found that 40% of military widows feel lonely or socially isolated, with some feeling abandoned by the military community. The researchers are calling for improvements to support available, not just after bereavement but in the months and years following.
The study reveals that more than 70% of patients developed urinary tract infections caused by endogenous E. coli strains from their own gut microbiota. The researchers also found that non-lactose-fermenting E. coli strains, less common in other countries, were present in the gut microbiota of some patients.
A University of Houston study found rural Americans are more anxious and depressed, with reduced openness and neuroticism compared to urban residents. Access to mental health services is believed to be a contributing factor.
Researchers developed an efficient algorithm that combines classical and quantum correlation functions to improve super-resolution microscopy. The algorithm, called 'super deconvolution imaging,' results in increased spatial frequency content, reduced mean squared errors, and faster imaging speeds.
A comprehensive review paper provides insights into the diffusion of pool fire combustion and fire dynamics, uncovering thermal feedback mechanisms and non-linear evolution of combustion rates. The research has significant implications for understanding pool fire behavior under varying environments.
A new review paper suggests that selective protection of normal cells from chemotherapy could increase the therapeutic window and improve outcomes for cancer patients. The authors propose using antagonistic drug combinations to kill drug-resistant cancer cells, reducing side effects and improving quality of life.
Researchers at Pusan National University have developed a novel FRET-based biosensor to detect double-strand breaks in DNA, providing real-time information on γH2AX. The sensor's sensitivity is higher than conventional immunostaining techniques, making it useful for identifying DNA damage factors and elucidating repair mechanisms.
A study from George Mason University found elevated insulin and hemoglobin A1C levels in early elementary-aged Latino youth with obesity, a risk factor for cardiometabolic diseases. The research aims to identify at-risk children and implement interventions earlier to mitigate the effects of childhood obesity.
Researchers have discovered higher levels of immune proteins in the blood before and after epileptic seizures. The study suggests a potential biomarker for epilepsy, which could be identified using a simple blood test. This finding may help distinguish epilepsy from other conditions, such as psychogenic non-epileptic seizures.
The article explores the role of forensic genetics in solving crimes using DNA analysis, familial DNA searching, and genealogical research. Forensic genetic genealogy has been successfully used to generate investigative leads for unsolved cases, leading to increased solved case rates and development of new investigative tools.
Researchers found that increasing melanin levels in human skin reduces Cherenkov emission intensity, while blood concentration affects different color channels. The study suggests using multispectral signatures to correct attenuated signals based on patient's blood volume or skin color.
A new study reveals that whooper swans thrive in UK nature reserves, with survival rates significantly higher and population growth up to 6% annually. This could lead to a doubling of the species' wintering population in the UK by 2030.
A digital health platform has been shown to reduce injury incidence in youth athletics by providing valuable information on adolescent growth and training loads. The study found that clubs with access to the platform had significantly lower injury rates, with injuries occurring twice as long after the start of the season.
A new study finds that 60% of purchased American foods contain additives, increasing by 10% since 2001. The study also reveals a significant rise in ultra-processed foods with additives, particularly among baby food purchases.
A study of multilingual children in Vanuatu found that they produced as much speech as monolingual populations, despite hearing fewer minutes of speech per hour. The strongest association was with vocalisations by other children, highlighting the importance of children's language acquisition.
A study by University of Michigan researchers found that older adults with dementia are at a higher risk of mortality after hurricane exposure due to disruptions in caregiving and daily routines. The analysis highlights the need for integrated preparedness and response strategies that address the special needs of people living with dem...
Researchers found that long-term antibiotic use during adolescence disrupts the healthy gut microbiome, leading to changes in liver metabolism that promotes central fat accumulation. The study suggests that antibiotic treatment may have lasting detrimental effects on liver metabolism and promote adiposity.
A new study assesses DNA metabarcoding's performance in identifying fish eggs on the West Florida Shelf, highlighting its value for long-term monitoring of spawning sites and habitats. The technique can identify multiple species from a single sample, but may introduce biases by excluding rare species.
Researchers discovered that great apes deliberately spin themselves to dizzy, mimicking human behaviors like whirling dervishes. This study suggests that humans may have inherited the need for altered states from their evolutionary ancestors.
Researchers found a strong association between high levels of telomerase reverse transcriptase (TERT) expression and an elevated immune response in patients with head and neck squamous cell carcinoma. This link suggests a potential new target for cancer immunotherapies, which may lead to improved outcomes for patients.
A European consortium has achieved a world-record solar-to-fuel efficiency of over 10% in converting CO2 and H2O into sustainable fuels using sunlight. The innovative cell produces hydrogen continuously (24/7) without the use of critical raw materials.
Researchers from Xi'an Jiaotong-Liverpool University identify vital differences between the plants, including pollinators and lifespan, confirming their classification. The study highlights the importance of recognizing every species for conservation programs.
A new study suggests CANDOR programs can improve staff's well-being and increase retention rates, addressing the growing concern of burnout among healthcare workers. The program aims to promote honesty in medical error situations, supporting both patients and healthcare professionals.
Researchers pioneered a technique to observe the 3D internal structure of rechargeable batteries, enabling direct observation of the solid electric interface (SEI) and its progression. The study reveals key predictors of SEI layer formation in a complex interplay of molecular dimensions, surface properties, and solvent interactions.
A team of Swedish and Norwegian palaeontologists has discovered remains of the earliest known ichthyosaur on the remote Arctic island of Spitsbergen. The discovery pushes back the origin and early diversification of ichthyosaurs to before the beginning of the Age of Dinosaurs.
A research team from HKUMed developed thyroid hormone (TH)-encapsulated nanoparticles that selectively target adipose tissues, reducing obesity-related metabolic complications and atherosclerosis. The treatment converts 'bad' white fat to 'good' brown fat, burning calories and alleviating hypercholesterolemia.
Researchers at University of Technology Sydney have successfully created personalized 'bio-inks' from patients' own stem cells, which are then used to 3D-print cardiac tissues to repair areas of dead tissue. This technology shows promise in treating heart failure and may reduce the need for expensive and traumatic heart transplants.
Researchers at Garvan Institute of Medical Research found that introducing bacteria to a tumor's microenvironment triggers an immune response, activating neutrophils to destroy tumors in animal models. This breakthrough therapy targets neutrophils to improve cancer treatment outcomes.
Researchers from Kumamoto University found that synchronizing ovulation and mating in
A recent study published in PNAS reveals that the protein TSKS plays a crucial role in eliminating sperm cytoplasm, enabling a streamlined structure necessary for successful fertilization. The findings suggest potential applications for diagnostic tests and male contraceptives.
A new device developed by quantum engineers can measure the spins in materials with high precision, breaking the current record of thousands of spins. This breakthrough enables researchers to study systems that were previously inaccessible, such as microscopic samples and two-dimensional materials.
A phase two trial found that exenatide significantly reduced brain pressure and monthly headaches in seven patients with Idiopathic Intercranial Hypertension (IIH). The study showed a rapid action of the drug, with results indicating significant reductions in brain pressure and headache days compared to the placebo arm.
A new technique involving a small flap in the peritoneum can reduce postoperative complications in prostate cancer surgery by allowing lymphatic fluid to escape and be absorbed. The study found that this technique significantly reduced the incidence of lymphocele, a common complication where lymphatic fluid collects in the pelvis.
The ProtecT trial found that active monitoring of prostate cancer has the same high survival rates after 15 years as radiotherapy or surgery. Men on active monitoring were more likely to see their cancer progress, but this didn't reduce their likelihood of survival.
A cross-disciplinary team developed a convolutional neural network to analyze microscopy images of chromosomes with cohesion defects. The algorithm achieved 73.1% accuracy in classifying new images, streamlining experiments with chromosome analysis.
A UK study reviewing over 90,000 vasectomies found that chronic scrotal pain occurs in just 0.2% of patients, while post-operative infection rates are around 1.6%. The study updates outdated figures and aims to encourage more men to undergo the procedure.
A study published by the European Association of Urology defines 'growers' and 'showers' as men whose penises increase in size by more than 56% when erect, compared to flaccid states. The researchers found that most men fell into a 'grey zone', with only 24% classified as growers and 25% as showers.
Domestic solar panel manufacturing in the US can reduce greenhouse gas emissions by 30% and energy consumption by 13% compared to international trading partners. By 2050, US-made solar panels will be more efficient, reducing carbon footprint by 33% and using 17% less energy.
A study of nearly 24,000 individuals reveals insurance status as a modifiable risk factor for racial and ethnic inequities in advanced cervical cancer diagnosis. Expanding access to care may mitigate these inequities.
A recent study published in JNCCN found that the lack of genomic research for people with African ancestry is hindering efforts to reduce disparities in prostate cancer outcomes. The researchers evaluated molecular genetic results for 113 Black South African men diagnosed with advanced prostate cancer, identifying 17 pathogenic and pot...
A team of scientists discovered a new genus and species of ancient gnat fossils in Mallorca, Spain, dating back to the early Middle Triassic period. The fossil, found near the harbor of Estellencs, shows how insects adapted to a post-apocalyptic world after a mass extinction event that wiped out over 80% of species.
Researchers have discovered unexpected similarities between stone tools used by monkeys and some of the earliest hominin stone artifacts. The findings suggest that accidental production of stone fragments during nut cracking may hold clues to the origin of intentional tool use in early humans.
Scientists have demonstrated a breakthrough in manipulating magnetic materials without using magnetic fields, paving the way for ultra-fast and energy-efficient memories. The researchers achieved sub-picosecond magnetization reversal in rare-earth-free spintronic structures, expanding the bandwidth of common devices.
A study found that telemedicine visits did not adversely affect the quality of care for patients with major depression, and even improved some aspects of care. The transition to virtual visits also led to increased adherence to measurement-based care practices.
A new study suggests that pregnant women who have dimmed lights and screens for three hours before sleep are less likely to develop gestational diabetes. Dim light exposure before bedtime may help regulate glucose levels, reducing the risk of this common pregnancy complication.
Researchers in Japan used a synchrotron to create gamma rays that revealed unusual fluctuations in the electrical charge of a strange metal alloy. The study provides insight into the inner machinery of these materials, which could inspire new forms of electronic matter and high-temperature superconductivity.
Researchers developed a new method combining pMINFLUX microscopy with graphene energy transfer, enabling axial precision of less than 3 angstroms. This allows for the study of molecular structures and dynamics at the nanoscale, fundamental for understanding cellular biomolecular reactions.
A new study found that Black patients with pulmonary fibrosis are significantly younger than their Hispanic and white counterparts, experiencing accelerated disease progression. Lifestyle and socioeconomic factors linked to environmental exposures may contribute to these disparities.
A team of microbiologists proposes using powerful microbial technologies to reduce global and local challenges leading to conflict, including food supply security and pollution. The authors advocate for deploying these technologies to address humanitarian crises and advance Sustainable Development Goals.
Peeter Laud's research aims to create a distributed identity system by removing single points of failure and improving privacy properties. He will explore how digital evidences can be issued privately using cryptographic technologies like zero-knowledge proofs.
A new study found that future incidents of simultaneous climate extremes will be exacerbated by human-driven climate change, with the strongest increases in tropical regions. Increasing concurrent temperature extremes will weaken tropical ecosystems' ability to act as carbon sinks, amplifying global climate change.
The γ-MnO2 dual-core pair-hole fiber enables the production of an all-fiber mode-locked laser with a pulse width of about 1 ps and a repetition frequency of about 600 MHz. This fabrication scheme offers good stability and is suitable for combining other novel materials with specialty fibers, expanding ultrafast optics and sensing appli...
Researchers found that phosphorus limitation decreases global and Chinese carbon sink strength by 7-16% by 2030s. The positive feedback between net primary productivity and soil decomposition amplifies this impact in China.