A new study proposes a simple coating solution to reduce degradation in solid-state lithium metal batteries. The coating, made of LiZr2(PO4)3 (LZP), improves capacity retention and decreases decay by mitigating uneven lithium-ion flux.
A German-Dutch research team has created the first map of the Microverse, redefining microbial niches. Generalists, which can cope with a wide range of conditions, dominate most habitats, while specialists have more specific environments and smaller genomes.
A group led by Virginia Tech's Audrey Ruple developed the PetSORT guidelines to standardize reporting in clinical trials involving dogs and cats. The guidelines address methodological features often missing from reported trials, which can affect meta-analysis results.
The article discusses concerns about the integrity of research and the well-being of participants due to financial conflicts of interest. The authors argue that disclosing these conflicts to potential participants may not achieve their intended moral goals, highlighting the need for improved policies.
A three-year randomized trial found that double-anonymous peer review reduces reviewer bias, with outcomes similar across author demographics. Single-anonymous review, where authors' identities are known to reviewers, resulted in biased ratings and more invitations for revision.
A team from Osaka University discovered that celastrol blocks the progression of rheumatoid arthritis by inhibiting a protein complex that promotes autoimmune responses. The researchers found that celestrol binds to COMMD3 covalently, preventing the formation of the COMMD3/8 complex and impairing antibody production.
A study published in eLife characterizes seasonal effects on human social behavior and indoor mixing patterns for respiratory disease transmission risk. The analysis reveals that the proportion of indoor to outdoor activity is seasonal, with stronger seasonality at northern regions and an additional summer peak in southern regions.
The study found that antibiotics slow down biofilm growth and QS molecule production across both strains, with surface type having a significant effect on the non-mucoid strain. The patterned structure was associated with longer latencies before expression of QS molecules were at their peak.
Researchers at TU Wien develop a quantum version of the third law of thermodynamics, finding that absolute zero is theoretically attainable but requires infinite energy, time, or complexity. This breakthrough reconciles quantum physics with thermodynamics, paving the way for the development of practical quantum computers.
A study found similar birth outcomes for same-sex lesbian couples undergoing ART compared to heterosexual couples who conceived naturally or through ART. Infertility-related factors, not reproductive treatments, contribute to higher adverse birth outcomes in ART pregnancies.
Researchers used computational modeling to identify ultrastable MOF structures, which could be useful for gas storage and catalysis. The study found that about 10,000 of the predicted structures were stable enough for these applications, with high deliverable capacities for methane.
A new study from the University of Kansas reveals significant racial wealth gaps and disparities in health outcomes among young adults. The study found that white and Hispanic individuals with higher wealth had better health outcomes, but Black respondents showed a more nuanced relationship between wealth and health. Policymakers argue...
Researchers found that traumatic brain injury suppresses the recycling function of both neurons and immune cells, including microglia and white blood cells. Boosting this process with a drug like rapamycin improves recovery in mice, reducing inflammation and enhancing memory function.
A recent study identified novel genes that influence PARP inhibitor response in prostate cancer, including MMS22L and RNASEH2B. The research found that loss of CHEK2, a previously approved biomarker, confers resistance to PARP inhibition, highlighting the need for comprehensive genomic analysis to improve treatment decisions.
Researchers highlight gaps in tritium studies, focusing on species uptake and human health risks through the food chain. A global assessment is needed to minimize tritium's impact on individual species and the environment.
Researchers are developing an alley cropping system to mitigate crop stress and promote soil fertility in organic vegetable production. The system involves planting trees between rows of vegetables, reducing heat extremes and improving biodiversity.
A new study in Human-Animal Interactions found that young dog owners prefer proactive coping styles when dealing with undesired behavior. The severity of behavioral issues was associated with the strength of emotions in response, with more severe issues eliciting intense emotions.
SourceCABI·JournalHuman-Animal Interactions·TypeExperimental study·DateApr 4, 2023
An international panel of experts has developed standardized definitions for immunotherapy side effects, providing a shared vocabulary for clinicians to standardize clinical practice guidelines. This will help support clinicians in offering the best treatment to patients and enable research into biomarkers predicting adverse effects.
A recent study by UPF's BCN MedTech defines a computational model that simulates protein interactions to pinpoint osteoarthritis causes in each patient. This model enables personalized and efficient treatments, which are currently challenging due to the disease's multifactorial origin.
A recent study on the pike icefish revealed significant genetic changes as it migrated from Antarctic to temperate waters. The researchers found divergent genes associated with the physiology that needed to change in response to the new environment, including mutations in the antifreeze glycoprotein gene.
The COVID-19 pandemic had a substantial and diverse impact on cancer care, with changes to screening, diagnosis, and treatment reported. However, the available evidence on how this affected cancer prognosis is limited.
A study of 12,000 older adults found that increased social, cultural, and community engagement was associated with more dental and outpatient care utilization and reduced inpatient care utilization. SCCE may promote beneficial health-seeking behaviors and optimize healthcare utilization.
A UCLA study found that individuals who support the Black Lives Matter movement tend to be less hesitant about receiving COVID-19 vaccines. The researchers suggest that altruistic feelings about interactions between different social groups may account for this phenomenon.
Using image-based computational blood dynamics, researchers mimicked health conditions and investigated hemodynamic parameters to better understand how aneurysm size affects blood flow. They found that altered blood flow velocity distribution can lead to rupture, emphasizing the importance of early detection and treatment options.
The study found that emissions of five CFCs increased after the production for most uses was phased out in 2010, reaching record-high abundance in 2020. The researchers warned that these emissions could contribute substantially to global warming and negate some benefits gained under the Montreal Protocol.
A recent study has identified 60 unique brain proteins that may influence body weight via their expression in the brain. Genetic factors are believed to contribute to up to 50-75% of BMI variation, with the brain playing a critical role in regulating energy homeostasis.
A new study found that US public support for redeemability of Black offenders is high, with 70-80% agreement on offender reform being possible and valued. Racial sympathy and White nationalism significantly influence beliefs in redemption and condemnation of Black offenders.
Researchers at Chalmers University of Technology have developed a unique method to reduce ship aerodynamic drag, which could lead to significant energy efficiency gains and reduced fuel consumption. The method uses the Coanda effect to create a more efficient airflow around the ship's superstructure, reducing drag by 7.5%.
Impact Journals' Oncotarget participates in the AACR Annual Meeting 2023, highlighting its focus on oncology and biomedical sciences. The meeting theme of Advancing the Frontiers of Cancer Science and Medicine aligns with Oncotarget's research goals.
Impact Journals will participate as an exhibitor at the AACR Annual Meeting 2023, showcasing Aging's growth in impact factor to 5.955. The meeting theme focuses on Advancing the Frontiers of Cancer Science and Medicine.
A recent study found that eight hours of social isolation can lead to lower energy levels comparable to eight hours without food. The researchers propose that this is part of our homeostatic response to social contact and may be an adaptive response, but also potentially maladaptive in the long run.
Researchers have successfully produced lab-grown fat tissue with a similar texture and make-up to naturally occurring fats from animals. The breakthrough could enable large-scale production of cultured meat with a more realistic texture and flavor.
A new study reveals a protein in the nervous system regulates collagen expression, potentially extending human lifespan as temperatures rise. Mutant worms with increased collagen production lived longer and looked younger than wild-type worms under warm temperatures.
A comprehensive study of 1,805 German forest insect species reveals a dramatic decline in populations over the past decade. The majority of evaluated species have decreased in number, with larger and more abundant species declining particularly.
A team of researchers at Eötvös Loránd University developed a general formula to calculate honest equilibrium in any model, independent of signal costs. Their results reveal that honesty does not require signal costs to be paid in equilibrium, and that the cost is borne by cheaters, not honest individuals.
Researchers used zircon crystals to unlock information about early Earth's magmas and plate tectonic activity, suggesting that the process was occurring more than 4.2 billion years ago. This finding could be beneficial in the search for life on other planets.
Astrocytes tune down overactive neurons during acute stress, helping to regulate attention and perception. This discovery provides new hope for treating attention disorders like ADHD.
Researchers have developed a new way to produce and shape large, high-quality mirrors that can be rolled up during launch and then precisely reshaped after deployment. The resulting mirrors are flexible enough to be used in space telescopes, enabling larger and more sensitive telescopes to be placed in orbit.
A UC Riverside study identifies how a Fragile X gene mutation contributes to premature ovarian failure, leading to early infertility. Researchers found that the mutation affects neurons regulating reproduction in the brain and ovaries, causing an increase in hormone production and faster secretion rates.
A UNIGE team created customizable treatments by testing drugs on artificial tumors derived from patients' cancer tissue. The approach opens the way for optimized and tailored therapies against various cancers and diseases.
A novel hydrogel enhances chemotherapy by targeting hypoxic regions in tumors, reducing metastasis. The gel's oxygen-scavenging properties improve the delivery of prodrugs, increasing its effectiveness against cancer.
Researchers at the University of Bath are developing a new power system for zero-emissions electric aircraft using liquid hydrogen fuel. The project aims to create a reliable and efficient superconducting DC distribution network, reducing environmental impact and noise in air travel.
A model shows enhanced rock weathering will only leak minimal carbon if its products are stored in the ocean. The technique may help constrain global warming below 1.5ºC or 2ºC by century's end.
Researchers used machine learning techniques to analyze seven years' worth of seismic data from Axial Seamount, identifying new signals including fin whale calls, tremors, earthquakes, and lava events. This study improves understanding of volcano dynamics and aids in predicting eruptions.
A new study published in JNCCN identifies a targeted approach to improve end-of-life conversations for people with cancer. Researchers found that specially trained oncology infusion room nurses can increase the rate of advance care planning, leading to more supported decision-making.
Researchers developed 'BioArm,' a portable 3D bioprinter for cancer research, which can print complex tumoroids in under 90 seconds. The device enables testing of immunotherapy treatments and mimics the tumor microenvironment.
Researchers Pawel Burkhardt and Fred Wolf will study the simple nervous system of marine organisms to understand brain evolution. The project aims to reveal the neural network of ctenophores, a predator with an alien-like brain.
A new approach to trauma-informed care, CARE, has been found to improve support organizations' care for survivors by better recognizing brain injury and addressing its often long-lasting repercussions. The toolkit helps staff proactively recognize these injuries and provides information about head trauma, strangulation, and mental heal...
A recent study revealed the key to a protein that commonly causes blindness, including its role in transporting toxic compounds out of the eye. Mutations in this protein can cause vision loss in diseases like Stargardt disease, which affects approximately 30,000 people nationwide.
The Arctic permafrost is home to thousands of industrial sites storing hazardous substances. As climate change accelerates thawing, these contaminants can be released, causing irreparable damage to ecosystems. The study estimates 13,000 to 20,000 contaminated sites in the region.
A new study published in the AATCC Journal of Research found that per- and polyfluoroalkyl substances (PFAS) in furniture fabrics have limited effectiveness in preventing stains. The researchers tested six PFAS-finished and three non-PFAS-finished fabrics, finding that only fabric type affected coffee stain performance.
A study reveals that neutrophils destroy liver cells undergoing apoptosis by burrowing into them, contradicting previous beliefs about their role in immune responses. The findings also suggest that a lack of neutrophils may contribute to human autoimmune liver disease.
A new study finds that clear and accurate information about the cause of death, provided in multiple formats, can influence family members' decisions to seek follow-up screening for inherited heart conditions. The study suggests that communication from death investigators and health care professionals is crucial in addressing families'...
Scientists at CiQUS have developed a methodology to quantify the folding degree of helical polymers, identifying the direction of helix rotation and its impact on structure-function relationship. The innovative approach allows for the estimation of folding degree and potential improvements in polymer performance.
A new shape-shifting antibiotic has been developed by Cold Spring Harbor Laboratory researchers, offering a potential cure for deadly infections caused by drug-resistant bacteria. The innovative design uses click chemistry to create a molecule with multiple possible configurations, avoiding the development of resistance.
Scientists developed a new clustering method to analyze similarities between chess openings, revealing ten distinct clusters that group similar strategies. The new classification complements the existing ECO Code and provides insights into player skill and opening complexity.
Patients with low sodium levels before or after total knee or hip arthroplasty are at increased risk of complications and adverse outcomes. Postoperative hyponatremia was linked to longer hospital stays, higher rates of discharge to rehabilitation centers, and readmission within 90 days.
Physicist Sekazi Mtingwa recognized for promoting accessibility, diversity, and equity in STEM. He co-developed the Bjorken-Mtingwa formulation solving intrabeam scattering effects, enabling more efficient particle accelerators.
A WPI researcher is leading a three-year project to investigate the effects of stretching and blood flow on cardiovascular cells in tissue-engineered heart valves. The project aims to expand understanding of mechanical forces that propel cells in the body, with potential applications in other fields like cancer and wound healing.
Researchers call for integration of creative science courses into curricula, emphasizing improvisational discussions and questioning existing assumptions to drive transformative science. This approach aims to reduce misconceptions among the public about the scientific process.
A new study by the University of Maryland School of Medicine found that ChatGPT provides correct information on breast cancer screening for most questions. However, inconsistencies and outdated information were detected in some responses. The researchers recommend relying on doctors for advice due to the limitations of ChatGPT.
A new proteomic risk model developed by Penn Medicine researchers is more accurate than existing clinical models for predicting cardiovascular risk among chronic kidney disease patients. The model uses nearly 5,000 proteins and identified specific proteins that can help identify individuals at high risk of future cardiovascular events.
A new study examines how socialization impacts gender-based research in marketing, finding that most studies focus on differences between men and women, with few exploring social construction of gender experiences and identities. Researchers recommend more diverse and inclusive methods to reflect current gender expressions.
A new study has made significant advances in understanding the underlying reasons behind crop yields, paving the way for engineering smarter plants to improve their productivity. Researchers have identified key elements that enable C4 photosynthesis, a process that allows certain crops to thrive in hot and dry environments.
Researchers at California NanoSystems Institute have developed a nanoparticle that delivers mRNA to specific cells in the liver, teaching the body's natural defenses to tolerate peanut proteins. The study found that the nanoparticle not only reversed existing peanut allergies but also prevented them from developing in mice.
A recent study found that conservatives are not easily persuaded by traditional pro-environmental messages, even when framed in terms of their own moral values. Instead, messages emphasizing loyalty, authority, or purity were equally effective in promoting pro-environmental behavior among conservatives.
Researchers analyzed 557 subjects to link genetic variations, brain structure, and behavior to intelligence test performance. They found specific brain areas where gene variations influence brain characteristics, which in turn affect intelligence.
A new study reveals that 26% of Canadian high school students have vaped in the past month, with 12% exclusively smoking vapes containing nicotine. The researchers found that male students are more likely to vape, and substance use is linked to higher odds of vaping with or without nicotine.
OncoMerge uses genetic data to analyze tumor activity and predict future changes. The software detects abnormal gene fusions and mutations affecting protein expression and gene copy numbers, improving the accuracy of cancer modeling predictions.
Researchers found that low-impact development practices, such as permeable pavement and bioretention cells, are effective in reducing flood risk in residential areas. Detention basins are also a viable option for areas with high impervious surfaces.
Researchers at the Forsyth Institute have discovered a molecule naturally produced by the human host that targets and inhibits Fusobacteria, an opportunistic oral pathogen linked to colorectal cancer. The findings suggest a chemically modified version of this molecule could be used as a potential therapeutic to prevent colorectal cance...
Researchers at the National Institutes of Health have found that immunotherapy can prevent the progression of low-grade lymphomatoid granulomatosis to high-grade disease. The treatment significantly improves survival rates for patients with the rare precancerous condition, with a median overall survival of over 20 years.
Researchers found that rats, like humans, tend to overestimate the likelihood of two events occurring together. This study suggests a shared cognitive mechanism between humans and animals, which could have implications for understanding psychopathological conditions.
Recent research by Norwegian University of Science and Technology revealed that East Antarctica's ice sheet melted rapidly along its margins between 9,000 to 5,000 years ago. The study suggests that the less stable, rapidly flowing parts of the ice sheet were broken up more easily, leading to the ice sheet becoming much thinner within ...
A new study by EPFL researchers has calibrated the best cosmic yardsticks to unprecedented accuracy, further amplifying the Hubble tension. The Hubble constant is measured in kilometers per second per megaparsec and has puzzled astrophysicists and cosmologists worldwide.
A new camera design allows for cheaper and more efficient long-term volcano monitoring, enabling researchers to track gas emissions and predict eruptions. The camera's affordability and user-friendliness make it accessible to more volcanologists, facilitating new research opportunities.
Researchers have developed a novel autonomous, submersible, 3D holographic microscope and imaging system to study marine particles and plankton in their natural environment. The AUTOHOLO system achieved 90% accuracy in detecting red tide blooms at varying concentrations, enabling near real-time monitoring and tracking of bloom phases.
Studies investigate multimorbidity, which is increasing due to improved survival from chronic diseases and population aging. The prevalence of multimorbidity varies greatly depending on the number and types of conditions considered, with some combinations spending more than the sum of individual diseases.
In a new study, NC State University researchers had high school students develop their own machine-learning AI models to analyze data. The project aimed to prepare students for the future workforce and help them understand the potential and challenges of AI. Students created text classification models using StoryQ technology, which all...
A new study analyzing over a million lonely hearts ads found that personality has become a more important factor than finances when it comes to dating. In Western countries, economic factors declined in importance, particularly after the 1960s, while in India, finances remained a key issue for people searching for love.
A team of researchers has created a mixed magnon state in an organic hybrid perovskite material by harnessing the Dzyaloshinskii–Moriya-Interaction. This allows for magnon-magnon coupling, which is crucial for processing and storing quantum computing information. The work expands the number of potential materials for creating hybrid ma...
Researchers provide a panoramic view of catalytic conversion networks for lignocellulose valorization, highlighting key reaction routes and products. The review aims to facilitate large-scale production and promote sustainable development through collaborative efforts.
The POSTECH team developed a multifunctional tip-enhanced spectroscopy that dynamically controls the physical properties of quasiparticles in 2D materials. This technology increases interlayer excitons' luminous efficiency by 9,000 times and modulates their energy.
Research by State University of New York College of Optometry suggests that reading lacks diversity in visual inputs, potentially leading to myopia development. The study proposes a mechanism where sustained reading reduces activation of ON pathways, causing eye growth beyond its focus plane and blurring vision at far distances.
A study published in Radiology found that ultrasound is an effective standalone diagnostic method for patients with focal breast complaints. The analysis showed that ultrasound alone led to accurate diagnosis in 90% of patients, with over 80% of complaints being benign findings.
Researchers find that patients with destructive nasal lesions may be suffering from cocaine-induced granulomatosis with polyangiitis, a condition often misdiagnosed. Cocaine use can trigger production of antibodies leading to symptoms similar to idiopathic Granulomatosis With Polyangiitis.
The Peking University team has developed a miniature three-photon microscope that successfully captured deep-brain images of freely moving mice. The new device features an innovative optical configuration, maximizing the collection efficiency of scattered fluorescence and achieving low phototoxicity.
A systematic review of clinical trials found that strength training with moderate to vigorous intensity, two or three times a week, can significantly lower blood pressure in hypertensive patients. The study analyzed over 21,000 scientific articles and concluded that effective results appeared around the twentieth training session.
Researchers at the University of Illinois have identified a novel class of ribosomal peptides called daptides, which exhibit hemolytic activity. This discovery opens up new avenues for therapeutic development and highlights the vast potential of undiscovered RiPP classes.
Researchers found that elephants exhibit hallmarks of domestication, including low aggression, empathic behaviour, and social learning. They propose that elephants' massive size and safe environment may have relaxed selective pressures for aggression, allowing for the evolution of prosocial behaviour.
Researchers found that COVID-19 infection leads to rapidly progressive dementia, blurring the lines between different types of dementia. Cortical atrophy and inflammation were key indicators, suggesting previously compromised brains have limited defense against new insults.
SourceIOS Press·JournalJournal of Alzheimer s Disease Reports·TypeObservational study·DateApr 4, 2023
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
A team at UC San Diego developed a biodegradable polymer system to treat rheumatoid arthritis by working with the immune system. The method uses encapsulated all-trans retinoic acid (ATRA) that transforms disease-causing cells into regulatory T cells.
A study found that monkeys with opposable thumbs were fooled by a sleight-of-hand trick, while those without were not. The French drop trick worked for capuchins and squirrel monkeys due to mirroring in their neural motor system.
In a 50-generation evolutionary experiment, male beetles from lineages with intense sexual selection produced lower quality offspring after DNA-damaging radiation. This suggests that males invest more in competition at the expense of DNA repair, impacting future offspring survival and fertility.
A study found that high deductible health plans may lead women to skip additional testing after an abnormal mammogram finding, particularly those with lower incomes and education levels. This can result in delays in diagnosis and treatment, worsening breast cancer outcomes.
Researchers found that infected mosquito saliva contains molecules called sfRNAs that can blunt the body's immune response. These molecules are injected during the mosquito bite, making it more likely for people to become infected with dengue virus.
Researchers at Ulsan National Institute of Science and Technology (UNIST) have identified seven types of zirconium metal clusters found in MOFs and fourteen potential new metal building blocks. This discovery provides a crucial clue to accelerate the development of carbon-neutral porous materials.
Researchers discuss cortactin's impact on cancer progression by modulating the Wnt5a/ROR1 signaling pathway. Cortactin expression is found in various cancers, including breast and chronic lymphocytic leukemia, suggesting its potential role in promoting metastasis.
During the early phase of the COVID-19 pandemic, prenatal telehealth visits substantially increased. The study found that deliveries in November 2020 had the highest telehealth visit rates during pregnancy.