Researchers at the University of Cincinnati found a link between latent tuberculosis infection and increased inflammation in monocytes, a type of white blood cell. This connection may contribute to a higher risk of cardiovascular disease in individuals with LTBI.
A new study published in the Annals of Internal Medicine shows that direct oral anticoagulant (DOAC) drugs are more effective and cost-effective than low molecular weight heparin for treating cancer-associated thrombosis. The research compared the three DOACs with low molecular weight heparin using a computer model that simulated major...
A University of Cincinnati researcher is leading a study to examine the effectiveness of a stroke treatment for patients with a pre-stroke disability, which are often overlooked in clinical trials. The study, funded by PCORI, will enroll over 1,100 patients across the US and collect data on outcomes such as disability, function, and qu...
A recent study found that COVID-19 vaccination rates vary widely across the US, with underserved communities facing significant barriers to access, including cost, insurance coverage, and transportation. The analysis showed that people in these areas were 34% less likely to be vaccinated against COVID-19.
A University of Cincinnati clinical research study found that participants who received on-site individualized nutrition education and shopping practice had a greater increase in adherence to a heart-healthy diet than the control group. The study, called SuperWIN, was conducted in partnership with Kroger Health.
A self-service vending machine filled with harm reduction supplies such as naloxone helped prevent overdoses and contributed to a decrease in Hamilton County's overdose deaths in 2021. Nearly 900 people used the machine since its installation, with nearly 16% of users reporting they had never used harm reduction services before.
A recent study published in Journal of Clinical Psychiatry found that only about 10% of children and adolescents who didn't improve with cognitive behavioral therapy opted for medication treatment. Patient characteristics, such as racial and ethnic minorities, younger patients, and expectations of treatment effectiveness, were identifi...
Researchers at UC challenge current timeline for mammoth extinction, citing limitations in dating environmental DNA. The team suggests that the slow decomposition of animals in arctic regions could explain how mammoth DNA is showing up thousands of years later than expected.
A new study from the University of Cincinnati examined workplace stress during the COVID-19 pandemic, revealing that increased workload and perception of COVID-19 exposure were major stressors. The research aimed to provide insights for organizations to reduce workplace stress and improve worker mental health.
A University of Cincinnati biologist is using a novel system to track the daily care of 47 northern bobwhite quail. The system uses wireless QR scanners to record health, food, water, and behavioral enrichment, making it easier to collect detailed data on animal welfare.
Researchers found that higher levels of polybrominated diphenyl ethers (PBDEs) in pregnant women were associated with increased anxiety scores in their children at age 12. The study suggests that exposure to flame retardants during early brain development may be a risk factor for developing anxiety symptoms in early adolescence.
A new study led by University of Cincinnati researcher Trisha Wise-Draper found that immunotherapy treatments may worsen COVID-19 disease in patients with baseline immunosuppression. However, patients who received COVID-19 vaccinations had less severe COVID-19 outcomes.
Researchers at the University of Cincinnati are awarded a $3.5 million NIH grant to examine how alcohol use alone or in combination with fentanyl affects HIV medications, including PrEP medication. The study aims to determine metabolite signatures and pharmacological biomarkers of PrEP in HIV-negative populations.
A University of Cincinnati study explores how anti-immigration policies affect Latinx mental health, finding increased depression, anxiety, and behavioral difficulties among affected communities. The research also identifies coping mechanisms that help individuals overcome these challenges.
Researchers found that ancient marine invasions in the Midwestern US, 446 million years ago, did not cause widespread extinctions. Instead, native generalist species adapted to accommodate newcomers. This ancient phenomenon can inform modern strategies for wildlife conservation.
A study by the University of Cincinnati found that veterans face a paradox of simultaneous stigma and social aggrandizement in organizations. They experience negative stereotypes, but also receive unwanted praise for their service. This can lead to conflicts over how to navigate their new civilian culture.
A new CAPSTONE study aims to identify inflammatory biomarkers associated with positive and poor outcomes in patients after intracerebral hemorrhage (ICH) strokes. By analyzing patient blood and plasma samples, researchers hope to develop targeted treatments to prevent long-term brain degeneration.
Researchers from the University of Cincinnati found that low levels of soluble amyloid-beta protein in the brain, rather than its buildup into plaques, are associated with cognitive decline and Alzheimer's disease. Patients with high levels of soluble amyloid-beta showed improved cognitive outcomes, contradicting previous theories.
Researchers at the University of Cincinnati found a significant link between poor metabolic health and low breast milk production. Women with conditions like insulin resistance, high blood pressure, and obesity were more likely to experience persistent low milk supply despite best breastfeeding practices.
A potential new treatment for glioblastomas, a deadly form of brain tumor, is being researched using the medication letrozole. Studies have shown that letrozole can be effective in killing tumor cells and reaching target tissue safely.
Researchers warn that pharmaceutical companies' pursuit of psychedelic treatments threatens Indigenous and counterculture traditions. Magic mushrooms have spiritual significance for many people, but corporations seeking patents and monopolies on these medicines are being criticized for their approach.
Researchers at the University of Cincinnati found that Burmese pythons have evolved super-stretchy skin between their lower jaws, enabling them to consume prey much larger than expected. This adaptation allows pythons to eat deer and other large animals whole, providing a significant energy advantage in their ecosystem.
A UC researcher is using information technology to track and study the endangered little brown myotis bat species in Ohio. The team has established a summer roost at Clendening Marina, where they are collecting data on the population's size and trajectory.
Researchers at University of Cincinnati found that emphasizing cost savings over global warming increases support for renewable energy sources. The study tested four messaging approaches and found durable bipartisan effects in favor of cost savings.
Researchers conducted a study on administering immunotherapy drug pembrolizumab before surgery for oral cavity cancer and found no increased rates of complications during and after surgery. The findings are encouraging for patients who have not previously received treatment for their oral cavity cancer, suggesting that complication rat...
Breast cancer recurrence and metastatic spread remain a significant challenge, with researchers identifying a metabolic signature that can predict patient outcomes. The signature could be used to develop new therapies targeting cancer metabolism.
Chemistry experts examined a decorative tassel on a 1,300-year-old Chinese dancing horse sculpture, discovering it was made of plaster and animal glue. The find provides new insights into the artwork's conservation history, suggesting multiple restoration efforts over centuries.
A massive landslide in Nevada's Red Rock Canyon National Conservation Area flattened an area larger than downtown Cincinnati, covering over 7 square miles. Geologists studied the landslide to better understand its dynamics and predict future landslides, which are a growing concern in areas with significant topography.
Researchers discovered the Griffin Warrior likely grew up near the seaside city he would rule and was from wealthier social status. Ancient DNA analysis showed that around 5,000 years ago, people with ancestry from Eastern Europe spread across the European continent and into Western Asia.
The study examines the complex factors contributing to vaccine hesitancy, including mixed media messages and concerns about effectiveness and safety. The researchers found that highly educated individuals were among those hesitant to receive the vaccine, highlighting the need for targeted education approaches.
University of Cincinnati researchers are studying whether targeting an inflammation pathway can improve patient results for soldiers with burn injuries combined with traumatic brain injuries. The research focuses on a specific protein that causes inflammation, which can lead to complications such as anemia and death.
The University of Cincinnati is conducting a study on a potential new treatment for pancreatic cancer using SapC-DOPG, a nanotechnology drug delivery system. The treatment has shown promise in reducing tumor growth by 50-80% in animal models and aims to develop an effective immunotherapy treatment.
University of Cincinnati researchers have discovered a technique using light-activated proteins to normalize dysfunctional mitochondria in cells. This method has the potential to treat certain diseases, including cancer and neurodegenerative disorders.
Researchers at University of Cincinnati and Case Western Reserve University found a novel drug enables nervous system repair and functional recovery in animal models of severe ischemic stroke. The study demonstrated significant improvement in motor function, sensory function, spatial learning, and memory. NVG-291-R repairs damage throu...
Researchers have developed a novel simulation method to calculate free energy using deep learning artificial intelligence, providing accurate models of molten salts' thermodynamic properties. The study could help examine corrosion in metal containers and improve the design of next-generation nuclear reactors.
Researchers created a machine-learning algorithm to predict neighborhood racial segregation, showing 86% accuracy in one test. The map analyzed census data and showed less segregated areas becoming more mixed by 2030.
Researchers found evidence of wild trees and plants growing near ancient Maya city Yaxnohcah, suggesting the civilization managed their environment prudently. The study suggests the ancient Maya cultivated pine trees for fuel, but also left much of the rainforest intact.
A new survey found dozens of non-native invasive species thriving in southwest Ohio's woods, including Amur honeysuckle, which is crowding out native plants. The study highlights the dangers of introduced species, such as allelopathy and fungal diseases that can wipe out native trees.
A recent study found that rural counties in the US experienced higher mortality rates during the Omicron wave of COVID-19, particularly among unvaccinated patients. Vaccination coverage was a significant factor in reducing patient outcomes.
A recent study found that certain bacteria species in the gut are associated with a higher risk of colorectal cancer in younger populations. The research suggests that dietary patterns high in processed meats, low-calorie drinks, and liquor may contribute to this increased risk.
Researchers at the University of Cincinnati are studying how lipids help fortify lung cancer cells and if targeting them can lead to better outcomes. The team discovered that lipids play a crucial role in cancer cell growth, membrane fortification, and energy production.
Researchers led by Atsuo Sasaki aim to identify mechanisms behind cell movement and energy allocation in cancer cells, with potential applications beyond cancer treatment. They will use scanning ion-conductance microscopy and machine learning technology to study the role of GTP in cellular migration.
A Phase 3 clinical trial is investigating the effectiveness of a combination of two immunotherapy drugs, nemvaluekin alfa and pembrolizumab, compared to standard chemotherapy for patients with platinum-resistant ovarian cancer. The trial aims to provide a novel treatment option with better efficacy and safety profiles.
Researchers found that mosquitoes whose slumber is disrupted are less interested in feeding, with a 54% decrease in feeding behavior. This phenomenon, called sleep rebound, highlights the importance of sleep for even insects.
Researchers at the University of Cincinnati found that a double layer of silk in combination with a surgical mask can enhance its ability to prevent the spread of viruses like COVID-19. The study also showed that double masking with a silk face mask prolongs the life of surgical masks without impeding breathing comfort.
Research found that even a single light source can throw off the butterfly's internal clock, leading to erratic movements and disrupted navigation. Monarchs rely on darkness to process proteins key to their orientation, but light pollution can disrupt this process.
A University of Cincinnati study found that adding blueberries to middle-aged diets may lower the chances of developing late-life dementia. The researchers discovered that blueberries' high level of micronutrients and antioxidants helped improve cognitive function and metabolic function.
Researchers at the University of Cincinnati are exploring a cost-effective solution to deploy in urban streams, such as adding fallen logs and branches. The goal is to create more standing pools for fish during droughts, slow periodic floodwaters, and reduce nutrients that can harm aquatic life.
Researchers from the US and Japan have discovered the mechanism of GTP recognition by a tumor-promoting kinase, leading to the evolution of a GTP sensor kinase. This finding could lead to the development of a new cancer-treating drug that targets PI5P4Kβ using GTP instead of ATP.
Researchers at the University of Cincinnati are searching for the ideal exosuit design to reduce muscle load and prevent work-related musculoskeletal disorders. The study found that commercially available exosuits have limitations, with the Auxivo LiftSuit being stiff and uncomfortable during prolonged wear.