Researchers from Nagoya University have identified two microRNAs that are downregulated in systemic lupus erythematosus, a disease where the immune system attacks itself. The study found that these miRNAs regulate the same set of genes through 'seed overlap' co-targeting, which negatively regulates inflammatory cytokine production.
A study by OHSU researchers found that immunity from COVID-19 gathers strength over time, indicating that vaccination should not be delayed. The study suggests that vaccine boosters can be spaced no more frequently than a year apart among healthy individuals.
A team of scientists has discovered a way to preserve quantum coherence in quantum dot spin qubits by exploiting the properties of a material with the same lattice parameter. This breakthrough improves storage time beyond hundred microseconds, paving the way for practical quantum networks and computing applications.
University of Central Florida researchers observed de Broglie-Mackinnon wave packets, a long-standing theoretical concept, by exploiting a loophole in 1980's-era laser physics theorem. The team's use of space-time wave packets, which resist stretching in dispersive media, verifies predicted properties and opens the path to studying top...
The study found that seismometers overlying the basin's deepest areas recorded stronger low-frequency amplification, while monitors at shallow edges recorded minimal amplification. Higher frequency amplification was detected in both deeper and shallower areas. This phenomenon is making the ground motion last longer and feel stronger.
A recent study found that heatwaves decrease phytoplankton biomass in a boreal lake by reducing the depth of the mixed layer. This reduction limits light and nutrient availability for photosynthesis.
A study analyzing local government spending on water infrastructure between 1980-2015 found associations with decreased poverty, increased per capita income, and unemployment. However, communities with higher Latino or Indigenous populations showed no significant effects, while Black American counties experienced stronger correlations.
Aston University is setting up the first integrated centre to explore low carbon hydrogen production from biomass conversion. The new research centre will enable the acquisition of state-of-the-art equipment, including gasification, membrane separation and fuel cells.
A new study reveals a significant increase in nocturnal production of nitrate radicals in China, which could exacerbate air pollution and pose a major health threat. The country's 'hot-spot' for nitrate radical production may worsen ozone and fine particulate pollution if emissions are not reduced.
Scientists successfully synthesized the elusive Λ(1405) particle and measured its complex mass, revealing a temporary bound state of a K- meson and proton. The findings may provide insights into the interior of ultra-dense neutron stars and the early formation of the Universe.
Evolution has occurred rapidly in Chesapeake Bay wetlands, potentially reducing the ability of coastal marshes to withstand future sea level rise. Plants now allocate less resources to roots below ground, allowing for quicker carbon storage, possibly due to increased pollution.
The Chan Zuckerberg Initiative grant will support advanced imaging training for over 2,000 scientists through a combination of hands-on events and online resources. Array tomography, an imaging technique that offers higher resolution and detailed molecular labeling, will be a key focus of the project.
The Faraday Institution has successfully scaled up its battery research to support the development of five projects funded by Innovate UK. These projects focus on recovering valuable materials and developing new battery technologies, such as quasi-solid-state lithium-sulfur batteries and solid-state pouch cells.
Using artificial human skin, researchers have successfully blocked invasive growth in a skin cancer model by targeting the TGF beta pathway. The study aims to develop new skin cancer therapies using existing drugs that can block these signalling pathways.
Scientists have discovered a connection between Amazon rainforest temperature changes and Tibetan Plateau climate patterns, highlighting the global impact of Earth system tipping elements. The study found a pronounced propagation pathway from South America to Tibet via Southern Africa and the Middle East.
Researchers demonstrate a model for developing probiotic therapies to modulate the microbiome by targeting intestinal biofilms and identifying beneficial microbial strains. The study showed positive effects in reducing GI symptoms and improving overall well-being in healthy individuals.
A new study found that Indigenous communities with formal tenure rights in Brazil's Atlantic Forest reduced deforestation and improved forest cover, outperforming territories without such rights. Strengthening self-determination rights of Indigenous peoples has been shown to be crucial for forest conservation efforts globally.
A recent study reveals that Native Americans have the highest rates of mortality from deaths of despair, including suicide, drug overdoses, and alcoholic liver disease. In contrast, white communities are often portrayed as being disproportionately affected by this phenomenon.
A diabetes screening program in an urban emergency department found high rates of undiagnosed prediabetes and type 2 diabetes among racial and ethnic minority individuals and low-income patients. The study suggests that targeted outreach to those with higher hemoglobin A1c levels may be more cost-effective.
A study found that standardizing evaluation processes and expanding telehealth use can significantly improve access to kidney transplants for African Americans. The interventions also led to increased organ acceptance rates, but post-transplant survival outcomes were not statistically significant.
Experts call for a nuanced discussion around gain of function research, highlighting its benefits for human health and its potential to reduce future disease outbreaks. The authors emphasize the need for evidence-based policies that balance safety concerns with the importance of this research in protecting humanity from viral threats.
A study by Hannes Wagner finds that governance mechanisms aligning investors' and directors' interests improve environmental performance. The study also shows a positive relation between the appointment of female directors and environmental performance.
A personalized brain modeling approach is being tested in a large-scale clinical trial for drug-resistant epilepsy, aiming to improve surgery preparation and patient specificity. The technique uses virtual models of patients' brains to simulate abnormal activity during seizures, helping clinicians identify target areas more effectively.
A new study published in Radiology: Cardiothoracic Imaging shows that photon-counting detector CT can acquire high-quality images at lower contrast media volume than conventional CT scanners. The technology reduces the amount of contrast needed for CT angiography, improving image quality and reducing environmental impact.
A new study published in The American Journal of Pathology suggests that promoting autophagy with rapamycin restores intestinal barrier function during sepsis. The study also identifies the PLK1-mTOR axis as a crucial regulator of autophagy and intestinal barrier dysfunction, providing novel insights for treatment of sepsis.
Research at Linköping University reveals that larger cities' benefits disproportionately favor the successful few, while typical residents receive little to nothing. The study highlights the growing inequality within and between cities, threatening the sustainability of urban life.
Researchers are using AI to assess soil datasets and measurements, aiming to build an automated data-driven decision support system for European soils. The goal is to create an effective soil health certification system that can be used by farmers, landowners, and policy makers.
A UC Riverside study found that fathers exposed to chemicals in plastics can affect the metabolic health of their offspring for two generations. Paternal DCHP exposure led to high insulin resistance and impaired insulin signaling in F1 offspring, while F2 offspring showed weaker effects.
A study published in Emerging Infectious Diseases suggests that long COVID affects up to 36% of university community members who tested positive for COVID-19. The research identifies potential risk factors, including vaccination status and underlying medical conditions, which can reduce the risk of developing long COVID.
A recent study reveals that the UK severely underestimates its greenhouse gas emissions from offshore oil and gas production by as much as five times. The researchers suggest alternative methods for calculating methane emissions, which could also apply to other countries.
Researchers developed AI algorithms to predict ICU delirium risk, showing promise in identifying patients at high risk. The models can detect early warning signs and provide continuously updated risk predictions, enabling clinicians to devote more resources to interventions.
The BepiColombo and Solar Orbiter missions provided a unique insight into Venus' atmosphere retention through their gravity-assist flyby. The study revealed that the induced magnetosphere protects the atmosphere from solar wind erosion, extending to an unexpected distance of 1,900 km above the planet's surface.
A new study found that Black and Hispanic hairdressers are exposed to a complex mixture of unknown chemicals, many potentially hazardous, and undisclosed on product labels. Researchers used advanced screening techniques to identify these chemicals and found higher levels in hairstylists compared to women working in office jobs.
Researchers at the Queensland Brain Institute developed a new ultrafast fMRI technique to study brain activity. The technique revealed that brain activity follows preferential circuits depending on cell type organisation, and blood signals can reflect network organisation and cell type distribution.
Researchers have discovered a way to produce limonoids, a family of valuable chemicals with potential as bee-friendly insecticides and anti-cancer drugs. By identifying the enzymes required for production, they can now use host organisms to create these compounds in a more sustainable way.
Disparities in access to pediatric ophthalmological care have increased over the past 15 years, with lower socioeconomic status being a significant factor. Online sources can lead to inaccurate databases, highlighting the need for accurate publicly available information.
Researchers developed BrightEyes-TTM, an open-source stopwatch to study molecular interactions inside living cells. The platform records the lifetime of fluorescent molecules, providing insights into cellular structure and function.
Researchers at KAIST developed a quadrupedal robot control technology that enables robots to walk robustly on deformable terrain like sandy beaches. The technology uses artificial neural networks to simulate ground characteristics and adapt to changing environments, allowing the robot to maintain balance and perform high-speed walking.
Researchers at IBS CSLM discovered pair quasiparticles in a classical system of microparticles driven by viscous flow. These long-lived excitations exhibit anti-Newtonian forces that stabilize pairs, similar to the behavior of Dirac quasiparticles in graphene.
A new measure called c-value helps researchers choose between techniques based on the chance that a new method is more accurate for a specific dataset. The tool answers questions like whether to use alternative estimation methods despite potential costs and effort.
A transnational collaboration led to the characterization of Physostegia chlorotic mottle virus (PhCMoV), a plant disease first identified in Austria in 2018. The study revealed that PhCMoV can infect at least nine plant species, causing severe fruit symptoms on economically important crops.
A new study by the University of East Anglia finds a significant association between low literacy and poor mental health outcomes across multiple countries. People with lower literacy skills are more likely to experience anxiety and depression, highlighting the importance of addressing literacy as part of mental health services.
Researchers created monthly infant brain atlases to track normative trends in brain development. The atlases reveal changes in brain structure, cortical geometry, and tissue contrast, shedding light on conditions like ADHD and dyslexia. The study aims to facilitate discovery of new insights into child cognition and social behavior.
Researchers developed a blood-based test that predicts Alzheimer's disease risk by analyzing changes in brain cell growth and division. The study found that the body's circulatory system can modulate the formation of new brain cells, and that this process occurs 3.5 years before a clinical diagnosis.
Researchers found a five-fold increase in autism cases among children with no intellectual disabilities, contradicting previous findings. The study suggests that better awareness and testing for ASD play a role in the observed surge.
Researchers from Utah State University have developed a new LiDAR system that improves the response time of commercial vehicles and detects movement without flaws. The technology can differentiate between stagnant and moving objects, see in the dark, and recognize potential collisions in real-time.
Researchers have discovered a new form of carbon, LOPC, which consists of 'broken C60 cages' connected by long-range periodicity. The formation of LOPC occurs under specific temperature and carbon/Li3N ratio conditions, and its characterization reveals unique electrical conductivity properties.
A new study published in The Journal of Nuclear Medicine found that e-cigarette users have greater lung inflammation than cigarette smokers and non-smokers. The study used PET imaging to compare lung inflammation between e-cigarette users and cigarette smokers, revealing a unique inflammatory response in the lungs.
Researchers have developed a new detector that can precisely measure single photons at very high rates, enabling practical high-speed quantum communication. The PEACOQ detector is made of superconducting nanowires and operates at extremely cold temperatures, allowing for precise measurement of photon arrival times.
Researchers at NYU Langone Health and the University of Toronto have developed a new AI tool called ZFDesign, which enables customizable protein editing for treating genetic diseases. The tool promises to accelerate gene therapy development on a large scale, offering a potentially safer alternative to CRISPR.
Researchers developed a cancer-selective therapeutic agent that targets cancer cells' unique acidic pH microenvironment, inducing mitochondrial dysfunction and killing only cancer cells. The agent, Mito-SA, forms charge-shielded nano-assemblies that selectively disassemble in the tumoral environment.
A German junior research group, RIMANUS, has been awarded €1.28 million to focus on refining imaging processes and monitoring nuclear fuels. The team aims to enhance reactor safety by developing non-invasive testing methods using cosmic-ray muons to inspect spent nuclear fuel storage containers.
A phase 2 clinical trial combining immunotherapy and targeted therapy showed a 24.3% confirmed response rate and 5-month median progression-free survival among patients with BRAF V600 mutations. The treatment also demonstrated increased durability, with 57% of patients remaining on treatment for more than 6 months.
Researchers from the University of Tsukuba have found distinct changes in brain activity patterns that can differentiate between Alzheimer's disease and Lewy body dementia. These changes were present before symptoms emerged and could be detected using conventional MRI.
Researchers at UC Irvine used super-resolution electron microscopy combined with deep machine learning to decipher minute changes in lithium-ion battery materials. This project enables the optimization of high-nickel-content batteries, improving their power and life cycles.
Researchers have discovered that primitive meteorites contain a different mix of potassium isotopes than those found in other, more-chemically processed meteorites. This suggests that the Solar System was formed from a 'poorly mixed cake batter' of materials, with some planets receiving a unique blend of elements from distant sources.
Researchers developed bioprinted artificial skin that mimics human skin, reducing animal testing in cosmetics and pharmaceutical industries. The model achieved similar results as traditionally produced models, passing international validation tests, including barrier function and irritant response assessment.
Researchers found a 200,000-light-year-long stellar tail emanating from F8D1, suggesting recent interaction with another galaxy. The discovery provides crucial evidence for understanding the origins of ultra-diffuse galaxies.
Researchers at MLU discovered a structure made of rings with four, seven and ten atoms that order aperiodically in titanium oxide. High temperatures and barium create this network of rings, stabilizing them through electrostatic interactions.
A new study in the Journal of Dairy Science confirms that milk packaging affects taste, with paperboard cartons and plastic bags imparting off-flavors and compounds to milk. Glass containers remain an ideal choice for preserving freshness, while plastic containers provide additional benefits.