Researchers at MedUni Vienna studied Covid-19's impact on lungs and colon, identifying novel biomarkers and treatment strategies. SARS-CoV-2 infections evoke different molecular mechanisms in pulmonary and gastrointestinal manifestations.
Researchers recreated primordial seawater containing phosphate in the lab, suggesting that seawater could be a major source of this essential element. This finding has implications for understanding the origins of life on Earth and potentially even beyond our planet.
Researchers at Case Western Reserve University found that chronic daily stress was beneficial against a second injury, inducing formation of immune cells called TLOs which protected against intestinal inflammation. The study also revealed an association between stressed mice and increased production of cytokines IL-23 and IL-22.
Scientists analyze environmental data to find temperature, rainfall, and pastureland areas as key factors contributing to viral transmission. The researchers project that areas hospitable to Lassa virus spread may extend into Central and East Africa in the next several decades.
Electrochemists have identified what makes nitrile additives effective at improving the performance of lithium-ion batteries using a lithium cobalt oxide cathode, opening up new avenues for further battery performance improvements.
In a new study, researchers found that immune T cells lacking the key transcription factor Satb1 are more susceptible to suppression by regulatory T cells, leading to transplant tolerance. The study provides insight into the mechanism behind transplantation tolerance and may lead to the development of new immunosuppression regimens.
A study by neuroscientists at New York University reveals that the brain's machinery interacts in nuanced ways to form long-term memories. The researchers found that neurons can sense not only repetition but also the order of repeated experiences, allowing them to discriminate between different patterns and build memories.
Climate variability in eastern Africa influenced hominin evolution, leading to anatomically distinct groups and modern human separation. Researchers analyzed lake sediment cores, revealing stable humid conditions, abrupt arid pulses, and extreme environmental shifts.
Researchers found no link between R&D costs and high drug prices in the US, contradicting industry claims. Despite $83 billion spent on R&D in 2019, drug prices are driven by market demand rather than investment costs.
Researchers at Champalimaud Centre for the Unknown discovered that female fruit flies engage in aggressive behavior during mating, triggered by courtship and food odors. The study found that virgins become aggressive after being courted first, while mated females remain indifferent to copulating pairs.
An international team developed two methods to protect and deprotect graphene nanoribbons from atmospheric oxidation, enabling scalable applications of their unique characteristics. The new strategy allows for the integration of carbon nanostructures into devices.
Researchers have identified the largest natural carbon onions, measuring up to 55 nm in diameter, within intrusion-affected coal samples. The discovery sheds new light on the synthesis of these onion-like structures during coal metamorphism due to magmatic intrusion.
A new study from St. Michael's Hospital found that a low-carb vegan diet has the same health effects as a vegetarian diet, but at a much lower cost to the environment. The researchers also discovered that the lower carbon emission value of the vegan diet was associated with a larger reduction in blood cholesterol.
Stronger hurricanes are more likely to reach Europe, with those encountering strong jet stream winds often reintensifying and moving further east. This study investigates the link between hurricane strength and European impact.
New research from the University of Georgia suggests that students who understand their strengths and weaknesses and are willing to ask for clarification and correct misinformation in small groups are more successful. The study identified seven types of metacognitive statements or questions associated with higher-quality reasoning.
UCF researchers have designed a cerium oxide nanoparticle to protect bones against radiation damage from cancer therapy. The treatment also improves bone regeneration and kills cancer cells, reducing the risk of bone fractures and tissue damage.
Researchers found that subcutaneous anchor securement systems significantly reduced catheter migration (1.76%) compared to other methods (4.17%, 6.77%, and 9.69%). The study adds to the evidence supporting the use of SecurAcath, which has been shown to reduce bloodstream infections and prolong catheter lifespan.
A new study by UC Santa Cruz researchers demonstrates 'transgenerational epigenetic inheritance,' where epigenetic marks are transmitted from parents to offspring and grandoffspring. This can lead to altered gene expression patterns in tissues, affecting health and development.
A joint research team from Korea and Japan developed site-specific organelle fluorescent thermometers that visualize temperature changes in almost all typical organelles. The new thermometers, called Thermo Greens (TGs), provide quantitative images of heat generation at different organelles, offering insights into cellular processes.
A new study identified a remdesivir-resistant version of COVID-19 in two kidney transplant patients treated with immunosuppressive drugs. The virus developed the V7921 gene mutation, which allows it to resist antiviral therapy, highlighting the need for continued monitoring and potential development of additional treatments.
Researchers found that kinship dynamics vary across species and sex, influencing helping behavior. In spotted hyenas, females' relatedness decreases with age, while males' increases, affecting their willingness to help groupmates.
A recent study found that over 11,000 people treated in US emergency departments for drug-related bike injuries were men, with methamphetamine being the most common substance involved. The study highlights the need for further research and interventions to prevent these incidents.
A study published in Cell reveals that the shape of receptor proteins determines axon targeting precision in mice, helping explain how olfactory neurons send signals to specific glomeruli. This discovery could lead to early detection of olfactory deficits and understanding of brain function.
Scientists developed a cellulose nanofiber-carbon fiber composite film with excellent in-plane anisotropic thermal conductivity, improving heat dissipation in thin-film devices. The material also exhibits recyclability and can be reused after burning the cellulose matrix.
A study found that building trust with community health workers (promotores) can lead to long-term self-care in type 2 diabetes patients. 32.4% of participants achieved 'self-care generativity,' while 40.5% progressed to 'stabilization.' The model, called Nosotros, could be replicated to improve chronic disease management.
A recent study from the University of Gothenburg found that young men aged 18-29 are most resistant to gender equality, while older generations are less so. The researchers identified factors such as unemployment and distrust in social institutions as contributing to modern sexism among young men.
Researchers at UT Austin fabricated a new type of electrode using magnets to create vertical alignment, enabling faster charging and potentially doubling range on single charge. The vertically assembled nanosheet networks show superior electrochemical performance due to high mechanical strength and electrical conductivity.
Women with anxiety about their pregnancies give birth earlier on average than those without anxiety. Doctors should screen for general anxiety early in pregnancy to prevent preterm birth.
Researchers at Indiana University School of Medicine have identified the autophagy pathway in hair cells linked to permanent hearing loss caused by aminoglycosides. The study developed laboratory models with reduced RIPOR2 expression, which did not exhibit hair cell death or hearing loss when treated with antibiotics.
Researchers investigate how interparticle interactions affect dynamical localization, a phenomenon where disorder brings particles to a standstill. In disordered systems with multiple interacting electrons, the system's behavior is closely analogous to that of an insulator.
A new study found that small mammals can serve as reservoirs for fungi that cause lung infections in humans. The researchers detected fungal pathogens in the lung tissues of rodents from areas with high rates of disease.
A recent study from the Paris Brain Institute has identified a region of the brain where the decision to procrastinate is made: the anterior cingulate cortex. The researchers developed an algorithm to predict participants' tendency to procrastinate, suggesting that procrastination is related to the impact of deadlines on task evaluation.
Researchers deciphered the ovarian reserve in cynomolgus monkeys using quantitative morphometric study. The study found that the number of primordial follicles decreased with age, with abundant reserves in perinatal periods and sharp decline during adolescence and adulthood.
The research team created a new porous silica/sulfur interlayer that achieves higher long-term stability than conventional materials, enabling more efficient lithium-sulfur batteries. By loading sulfur in the intermediate layer, they increased capacity per cell area and improved battery performance.
Research reveals that gut flow velocity directly affects nutrient absorption and bacterial levels, with optimal conditions for each. The study suggests the gut adjusts its flow speed to regulate these processes in response to meal intake or fasting, potentially preventing diseases such as chronic fatigue and poor nutrient absorption.
A team of scientists studied how relatedness to a social group changes with age in seven mammal species, finding that incentives to help or harm shift depending on the species' social structure and gender. This understanding can explain differences across species and sexes.
A new study by UC Santa Barbara researchers Anabel Ford and Mattanjah de Vries reveals that cacao was accessible to the general populace and used in celebrations at all levels of ancient Maya society. The analysis of 54 archaeological ceramic sherds from El Pilar, Belize, found evidence of cacao residues in all vessel types, including ...
A cohort study found that endoscopists performing colonoscopies in FIT-based screening programs should aim for markedly higher ADRs compared to primary colonoscopy screening. The study suggests that high ADRs are associated with lower colorectal cancer incidence and mortality. Researchers recommend using ADR targets, including differen...
Researchers found that basaltic magma chambers can grow extremely rapidly, with rates of hundreds to thousands of meters per year, producing large, well-differentiated intrusions. This challenges current understanding of slow growth rates for such formations and suggests a new perspective on the formation of layered mafic intrusions.
A University of Washington study found that heat-related mortality is a current environmental public health problem in Washington state, even in temperate areas. The study analyzed deaths from 1980 to 2018 and found significant increases in mortality on days with high humidex values.
The University of Exeter team identified a 'master regulator' that controls the formation of invasive hyphae in the fungus Zymoseptoria tritici. This discovery provides a crucial target for developing new control strategies against Septoria tritici blotch, a destructive fungal disease affecting wheat yields worldwide.
Research by Kirill Kavokin found that around 100 hair cells in an animal's inner ear can act as effective biological compass needles, allowing them to detect the magnetic field. This discovery could bring biologists closer to understanding the origins of magnetoreception and identifying mechanisms responsible.
A machine learning multi-city model is developed to predict municipal solid waste generation in China, using a wide range of feature variables. The model shows good performance with an R-squared value of 0.939 and is suitable for predicting MSW generation in China.
A new scoring tool prioritizes countries with higher vaccination rates and vulnerable populations, aiming to allocate Covid-19 vaccines more fairly. The tool considers a broader range of factors than current global COVAX facilities, which have been criticized for insufficient access.
Researchers at the University of Toledo found that consumption of highly refined fiber may increase liver cancer risk in some individuals, particularly those with a silent vascular deformity. The study discovered that high concentrations of bile acids caused by a portosystemic shunt led to the development of liver cancer.
Researchers at UVA Health have developed a new magnetic-resonance imaging (MRI) technique to track peripheral artery disease, which affects over 200 million people worldwide. The CEST approach produces comparable results to the current gold standard without requiring specialized equipment.
A study conducted at the University of Zurich has identified a key gene network responsible for severe tooth enamel defects. The researchers found that mutations in the Adam10 molecule lead to disorganization of ameloblasts and severe defects in both structure and mineral composition of enamel.
Physicists used machine learning to compress a complex quantum problem into four equations, capturing the physics of electrons on a lattice with high accuracy. The approach could revolutionize how scientists investigate systems containing many interacting electrons and potentially aid in designing materials with sought-after properties.
August COVID Update data show little change in unemployment numbers for people with and without disabilities on temporary layoff or looking for work. Challenges are on the horizon due to inflation concerns, which may lead to a tightening of the labor market and rising unemployment.
A study identifies a molecule called NIK that promotes the growth of bile duct cells in the liver, leading to scarring and liver fibrosis. Removing NIK or blocking its action with inhibitors may prevent disease progression.
Researchers at Bangor University used multibeam sonar to positively identify the SS Mesaba, a merchant ship that sent an iceberg warning to the Titanic in 1912. The wreck was found in the Irish Sea, revealing new information about this infamous maritime event.
Researchers developed a novel 3D microfluidic device to study complicated processes within the placenta, including placental malaria. The model demonstrates that CSA-binding infected erythrocytes add resistance to the simulated placental barrier for glucose perfusion and decrease glucose transfer across this barrier.
A free web-based resource called Menstruation Matters has been developed to provide young people with accurate information about menstrual health. The study found that nearly half of participants reported a change in their understanding of what a normal period is, and 94% could identify symptoms of endometriosis.
MIT researchers create a low-power, sound-harvesting camera that captures color photos and transmits data wirelessly. The autonomous device can run for weeks without power, enabling scientists to explore remote oceans and monitor climate change impacts.
A large observational study found that moderate coffee consumption, including decaffeinated and ground coffee, was associated with reduced risk of cardiovascular disease and death. The study suggests that mild to moderate intake of coffee can be part of a healthy lifestyle.
A new study led by Yale University's Nyeema C. Harris found that 91 African carnivore species have some portion of their range at risk of contraction, with an average of 15% of ranges threatened. The research introduced a novel approach to assessing threats and assets across species ranges.
Researchers at Cornell University suggest that bright reflections on Mars' South Pole may be caused by layered composition rather than liquid water. The team's simulations showed that layer thickness and separations have a greater impact on reflection power than material composition.
Researchers at FIU Stempel College are investigating the translocator protein 18 kDa (TSPO) in relation to Alzheimer's disease. They aim to determine if an increase in TSPO levels is harmful and may be a potential target for treatments.
Researchers at the University of Colorado Boulder have developed a method to break down durable plastics into their most basic building blocks and reform them into the same material. This breakthrough could lead to the creation of new technologies, new materials, and enable the circular production of more plastic materials in daily life.
A public consultation is launched to develop best-practice standards for diverse and inclusive healthcare datasets used in Artificial Intelligence. The project aims to reduce biases that affect patients from minoritised racial/ethnic groups, ensuring they receive accurate predictions and treatments.