A study suggests young people are hesitant to use digital mental health resources due to lack of trust in their effectiveness. Researchers found that perceived ease of use and mental health need did not significantly impact intentions to use a resource.
Researchers at the University of Pittsburgh discovered that exhausted cancer-fighting T cells can become immunosuppressive when working in low-oxygen tumor environments. Targeting these conditions can reinvigorate these cells, improving response to immune-based cancer therapies.
Studies found underrepresentation of American Indian, Asian, Black, and Latinx groups in obstetrics and gynecology research. The disparity varies by race, ethnicity, subspecialty, and funder, with some subspecialties having more diverse trials than others.
Scientists have identified genetic subgroups of a common coral species in Palau's Rock Islands that exhibit remarkable tolerance to extreme heat. The corals' larvae travel from their birthing grounds to the outer reef, where they survive and maintain their heat tolerance.
Researchers found that brains process register-incongruent words similarly to semantic anomalies, requiring additional effort. Listening to sentences with stylistically out-of-context words elicits the N400 component, indicating increased cognitive load.
A new study suggests that an orbiting space probe could provide definitive answers about the presence of life on Enceladus' ocean. The team mapped out how a hypothetical mission could gather data from the moon's plumes, which are thought to contain organic molecules and methane.
New study reveals marine algae adapt to nutrient-poor ocean conditions, sustaining productivity even in depleted waters. This 'metabolic hack' could impact global ocean productivity and carbon sequestration.
A new mathematical model has found a clear trend towards mutualism in ecological interactions, with most relationships eventually leading to a mutually beneficial partnership. The researchers used adaptive dynamics and classical models of population dynamics to study the transitions between different ecological relationships.
A new study found that drinking two or more cups of coffee daily may increase the risk of cardiovascular disease mortality among people with severe hypertension. In contrast, moderate green tea consumption did not show a significant association with increased risk, suggesting potential benefits of polyphenols in reducing mortality.
The ESCAPE-NET project reveals that primary care visits increase before a sudden cardiac arrest, providing an opportunity for prevention. The study's findings highlight the need for targeted efforts to identify individuals at risk and improve survival rates.
Recent changes in climate change coverage in college biology textbooks have been minor and focus on the impacts rather than solutions. The analysis of 57 college biology textbooks since 1970 shows that coverage has continually expanded, but the proportion of text dedicated to actionable solutions has decreased over time.
Researchers at The University of Tokyo have developed a cheap and simple method to bond polymers to galvanized steel, resulting in lightweight and durable materials. The process involves pre-treating the steel with an acid wash and dipping it in hot water, creating nanoscale needle structures that allow for strong mechanical linkages.
Researchers at Georgia Institute of Technology found that AI chatbots' positive emotional displays have no effect on customer service evaluations when the source is a bot, but improve when human agents exhibit emotions. The study suggests businesses should be cautious about equipping AI agents with emotion-expressing capabilities.
Researchers have identified a rare gene mutation that causes severe childhood obesity, leading to a constant feeling of hunger and decreased sensation of satiety. The discovery provides a new understanding of the genetic mechanisms underlying monogenic human obesity.
A new Northwestern Medicine study found that all U.S. OB-GYN subspecialties lack racial and ethnic representation in clinical trials and research publications. This absence has negative consequences, including biased tools for diagnosing endometrial cancer and unacceptably low sensitivity in the Black female population.
A recent study has identified common and unique cellular processes in six neurodegenerative diseases, providing new insights into the underlying causes of these conditions. The research used machine learning analysis to compare RNA markers in whole blood samples from patients with distinct diseases, revealing eight shared themes across...
Researchers discovered that damaged cells and aging induce high levels of oxidative stress and DNA damage in a subset of cells, leading to senescence. Senescent cells repress muscle regeneration by releasing inflammatory factors, while also promoting fibrosis, highlighting the need to remove these cells for improved repair.
The CodeBreaK 100 trial demonstrates meaningful anticancer activity with sotorasib in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer. The results show an objective response rate of 21.1% and a median time-to-response of 1.5 months.
A new injectable hydrogel has been developed to rapidly stop bleeding from traumatic wounds. The material becomes solid when injected into the body and can be easily washed away with a cold saline solution.
As we age, fat cells replace immune system tissue in lymph nodes, impairing their ability to fight infections and respond to vaccinations. This phenomenon, known as lymph node lipomatosis, is more common and prevalent with age, affecting the effectiveness of our immune system.
Research published in Developmental Medicine & Child Neurology reveals a link between maternal diabetes and neurodevelopmental disorders such as autism, ADHD, and intellectual disability in children. Type 1 and type 2 diabetes were associated with increased risks of these conditions, while gestational diabetes was linked to autism spec...
A systematic review and network meta-analysis found that acupressure has a greater effect on reducing sleep disturbance in patients with cancer. The study suggests that nurses should be trained in acupressure to help patients experiencing sleep problems. The analysis included 24 randomized controlled trials involving 2,002 patients.
Researchers at POSTECH developed high-performance n-type semiconductor Bi2S3 and p-type Te semiconductor through thermal evaporation, reducing energy consumption and environmental impact. This method can be integrated into standard OLED manufacturing, lowering production costs and contributing to the growth of sustainable electronics.
A study by Duke University Medical Center reveals that loss of smell in long COVID-19 is caused by an ongoing immune assault on olfactory nerve cells and a decline in their number. The finding also sheds light on possible underlying causes of other long COVID-19 symptoms.
University of Wisconsin-Madison researchers Hayley Boigenzahn and John Yin investigated the potential role of the drying process in prebiotic chemistry. They found that amino acids could bond together into peptides during periods of environmental change, such as when a pool of water evaporates.
Neuroscientists have uncovered a brain circuit that enables mice to rapidly escape to shelter when faced with a threat. The retrosplenial cortex and superior colliculus form a circuit that encodes the direction to a shelter, allowing mice to accurately orient and escape.
Scientists from CHOP and NJIT created a software tool to analyze information from a single cell, revealing relationships between different cellular characteristics. The 'single-cell multimodal deep clustering' method can help identify the causes of genetic-based diseases by integrating data on gene expression, mRNA, proteins, and organ...
A new study found that Black patients have lower odds of undergoing minimally invasive mitral valve surgery and higher odds of serious complications or death compared to white patients. This inequity is linked to factors such as Medicaid insurance, hospital resource, and surgeon experience.
Researchers review recent advancements in carbon-based electrochemical catalysis, highlighting progress in designing high-performance catalysts with controlled active sites. Despite this progress, challenges remain, including efficient synthesis strategies and scaling up production for practical applications.
A new rapid test developed by the University of Würzburg uses magnetic nanoparticles to detect antibodies against SARS-CoV-2 with high sensitivity. The test takes only a few seconds to produce reliable results, enabling faster diagnosis and treatment of infectious diseases.
Researchers linked the mutation that causes Huntington’s disease to developmental deficits in oligodendrocyte cells caused by metabolism changes. High doses of thiamine and biotin treatments restored normal cellular processes.
A study by researchers from the University of Tsukuba found that treating cabbage leaves with multiple amino acids can prevent disease caused by Pseudomonas cannabina pv. alisalensis, a bacterium that causes blight in brassica crops. The amino acids trigger stomatal closure, reducing bacterial entry and disease symptoms.
A University of Houston study found that anger over how the industry responded to the pandemic is a major driver behind hospitality workers' reluctance to return. The research team suggests that rebuilding trust with employees and offering better compensation and benefits are key recommendations for businesses.
A new algorithm developed by researchers at Charité improves motor symptoms comparable to standard of care treatment, increasing efficiency in deep brain stimulation for Parkinson's disease. The study suggests a promising result for imaging-based algorithms to simplify clinical practice and improve therapeutic outcomes.
Researchers found that deep-sea trenches store 500,000 to 1.5 million tonnes of black carbon annually, which is a significant contributor to the global carbon cycle. This organic material can also support microbial life forms, counteracting the rate of CO2 accumulation in the atmosphere.
The Inflation Reduction Act offers significant benefits for public health through its tax credits and financial incentives. The law aims to reduce the adverse health effects of climate change by targeting greenhouse gases, conventional air pollutants, and carcinogenic chemical contaminants. By providing a more politically feasible appr...
The Endocrine Society's Clinical Practice Guideline provides suggestions for the treatment of hypercalcemia of malignancy, a common and life-threatening metabolic complication of cancer. Treatment options include intravenous bisphosphonates or denosumab medications, with denosumab recommended as the preferred choice.
Non-Hispanic Black patients are less likely to undergo minimally invasive mitral valve surgery and experience poorer outcomes compared to non-Hispanic white patients. Increasing access to private insurance and high-volume surgeons may be necessary to address these disparities.
A study by researchers at the University of Tsukuba found that a 'valley of recovery' marks progress after a stroke, where performance initially slows before improving. The study modeled fine motor skills regained after a stroke to better understand this process.
Researchers compared zebrafish and medaka bones, finding medaka lacks bone cells but retains water-absorbing Proteoglycans. The study suggests a new explanation for why some bones respond better to stress than others.
A study found that acidification of aerosols post-exhalation significantly impacts viral load. Influenza A viruses are inactivated within minutes, while SARS-CoV-2 requires days at typical indoor pH levels.
Bicycle-related injuries in the US decreased over time, with an increasing rate of injuries among older patients, particularly head injuries and fractures. Helmet wearing is crucial regardless of age to prevent such injuries.
A global study has discovered a gene, SULT1A1, that may help reduce the risk of breast cancer, especially in women with BRCA1 gene mutations. The study, involving over 26,000 women, found that reducing levels of this protein can lower breast cancer risk and is being used to develop a new risk-reducing drug.
Researchers from City University of Hong Kong developed a novel device-engineering strategy to suppress energy conversion loss in organic photovoltaics, achieving PCE over 19%. The discovery enables OPVs to maximize photocurrent and overcome the limit of maximum achievable efficiency.
The UT Extension Center for Profitable Agriculture project is studying six niche crops: cut flowers, persimmons, blueberries, elderberries, garlic, and microgreens. The project aims to provide education and outreach to help Tennessee producers make informed decisions about marketing and sales.
A team at Lawson Health Research Institute discovered unique patterns of blood plasma proteins in critically ill COVID-19 patients, which may aid in developing targeted therapies. By analyzing over 1,000 proteins, researchers found changes in immunosuppression pathways and identified potential biomarkers for the disease.
Dupilumab, an FDA-approved medication, offers new hope for patients with eosinophilic esophagitis, a rising condition in the US. The treatment reduces eosinophil counts and improves symptoms of dysphagia, leading to better endoscopic healing and histologic severity improvements.
Research found that people using social media to escape superficial boredom are preventing themselves from progressing to profound boredom, a state that can lead to more creative and meaningful activity. Profound boredom stems from uninterrupted time spent in solitude, allowing individuals to question their sense of self and existence.
New research reveals that California nursing homes exposed to wildfire risks have poorer compliance with emergency preparedness standards. The study found that 83.9% of these facilities had at least one deficiency compared to 76.9% of unexposed ones.
A cross-cultural study found that Ugandan mothers have more relational attitudes toward parenting, while UK mothers focus on autonomy. Despite these differences, infant experiences vary across cultures.
The Society for Healthcare Epidemiology of America recommends against routine COVID-19 testing for symptom-free patients. Instead, enhanced infection prevention interventions should be used to protect patients and healthcare providers.
Researchers have developed an improved genetic test that allows for more accurate prediction of which parent's genes led to an individual's increased cancer risk. The new test confirms whether a cancer predisposing gene variant is present in a patient and determines its origin, enabling targeted prevention efforts.
Research finds that intentional celebrations can boost perceived social support, a key factor in health and well-being. Celebrations with social gathering, eating or drinking, and marking positive life events increase this belief.
Scientists at ASHBi have successfully generated a 3D model that recapitulates the early stages of human body plan development, including somite formation and axial skeleton development. The study revealed the importance of retinoids in this process and demonstrated its potential for understanding congenital spine disease.
Scientists at Seoul National University and Korea University created a new method to detect molecular chirality, a property crucial in biology, chemistry, and pharmaceutics. They achieved ultrasensitive detection of up to 10^-4 M using chiral plasmonic nanoparticles with four-fold rotational symmetry.
A recent study published in PLOS ONE found that faces paired with fake news headlines are perceived as trustworthy regardless of disputed labels. The research suggests that long-term perceptions of trustworthiness are more influenced by the content of the headline rather than the label itself.
A recent study by University College London reveals that the COVID-19 pandemic has exacerbated mental health issues and food insecurity among individuals living with obesity. Nearly half of participants reported worsening mental health, while nearly a third experienced severe depression. Food insecurity also increased significantly, wi...
Researchers have uncovered a rare piece of evidence showing Microraptor, a small feathered dinosaur, ate mammals. The preserved gut contents contain the foot of a small mammal, providing conclusive proof of a diverse diet for this species.
This study uses high-quality observations and CMIP6 model data to constrain future solar radiation projections in China. The research reveals that clouds and aerosols cause significant biases in projections, resulting in large uncertainties. Constrained results significantly reduce projection uncertainties by about 56%.
Georgia Tech researchers developed a new nanoelectronics platform based on graphene, enabling smaller devices, higher speeds, and less heat. The platform may lead to the discovery of a new quasiparticle, potentially exploiting the elusive Majorana fermion.