Researchers at UC University challenge prevailing Alzheimer's theory by discovering that normalizing brain protein levels can prevent cognitive impairment. The study found a correlation between high levels of soluble amyloid-beta peptide and normal cognition, suggesting future therapies should focus on replenishing these proteins.
Scientists at the University of Cincinnati have developed a blueprint for the protein anti-Müllerian hormone (AMH), which plays a crucial role in reproductive organ development. Understanding how AMH interacts with its signaling receptor may lead to novel treatments for infertility, polycystic ovary syndrome (PCOS), and even feral cat ...
Researchers found over 30 species of plants along the banks of Tikal's reservoirs, including trees like ramón and cabbage bark. The study suggests that the Maya protected these areas as sacred groves to provide medicinal or edible plants and fruits.
Researchers at the University of Cincinnati found that poorly fitting face masks can double the infection risk to wearers and others, while custom-fitted masks greatly reduce this risk. The study used CT scans to measure gaps between faces and masks, revealing substantial leaks around the nose that compromise mask effectiveness.
A national study by University of Cincinnati researchers has identified 25 geographic hot spots for fatal opioid overdoses and linked them to poor mental health. White males aged 25-29 are most at risk, followed by white males aged 30-34, with a correlation between fatal overdoses and mental distress increasing the relative risk by 39%
Researchers and community members collaborate to develop a program promoting healthy eating habits in infants, addressing real barriers faced by families. The study aims to improve nutrition and behavior outcomes, with the goal of reducing obesity risk later in childhood and adulthood.
A University of Cincinnati researcher has found that plasma proteins discovered in the blood samples of diabetic patients who developed obstructive coronary disease may serve as biomarkers of severe heart blockage. This discovery could help patients with diabetes identify their risk and receive timely medical attention.
Researchers from the University of Cincinnati discovered that some BPA-free drinking bottles can contain traces of BPA, a chemical linked to heart health issues. The study found that multiple cycles through the dishwasher effectively removes BPA from these bottles.
A recent study by the University of Cincinnati found that inactive oil wells in Texas can leak significant amounts of methane, with some emitting up to 132 grams per hour. The study suggests that regular inspections using infrared cameras could help address the issue.
Researchers at the University of Cincinnati found that a protein in skeletal muscle fibers regulates the body's fight or flight response, enabling quick bursts of power. This discovery may lead to advancements in understanding and addressing skeletal muscular disorders.
Researchers at the University of Cincinnati have developed a new treatment for Pompe disease, a genetic condition that affects 1 in 40,000 people in the US. The treatment has been shown to be safer and more effective than current therapy, improving respiratory muscle function, endurance, and overall quality of life.
Researchers found that high levels of particulate matter exposure were associated with a 60% higher chance of hospitalization in COVID-19 patients with pre-existing respiratory disease. Patients without respiratory disease showed no increased risk. Air pollution may have policy implications, such as reducing particulate exposure.
A new study by UC researchers uses brain imaging to predict treatment outcomes for adolescents with anxiety disorders. The study showed that medication can 'dampen' the overactivity of fear areas in the brain, leading to improved transmission of messages between neurons.
A new study estimates an 'eliciting dose' for peanut allergies, revealing that tiny amounts can trigger reactions in some individuals. The researchers found that exposure to 0.052 milligrams of peanut protein is likely to cause or elicit an allergic reaction in 1% of patients.
Children exposed to tobacco smoke are more likely to use emergent health services, leading to higher costs and toll on the nation's healthcare system. The study highlights the need for prevention strategies such as standardized interventions in urgent care settings and promoting smoke-free home and car policies.
Researchers used quantum simulations to understand glycerol carbonate, a compound that could improve lithium-ion battery efficiency and reduce environmental impact. The study revealed new details about hydrogen bonding and its effects on solvent properties.
University of Cincinnati assistant professor Ashley Ross is developing tools to detect and study chemical signals between the brain and immune system using a federal grant. Her research aims to understand how neurons regulate inflammation and develop new therapies.
Researchers are developing an ocular drug delivery system based on RNA nanotechnology to deliver therapeutics into the eye without requiring eye injections. This method aims to create a reservoir for medications to treat diseases over time, reducing adverse effects and increasing treatment efficiency.
A global multicenter study has uncovered a correlation between the severity of COVID-19 in the lungs and brain using CT/MRI scans. Researchers found that patients with more severe respiratory disease are more likely to experience neurological symptoms, such as stroke and brain bleeds.
Researchers have identified 1,600 genes related to stable fly reproduction, which could lead to new biological controls. The study's findings have huge economic implications from tourism to agriculture, with estimated annual losses of $2.2 billion.
UC researchers found that cooperation between HER2 and MED1 genes promotes breast tumor growth, spread, and treatment resistance. Targeting MED1 alone or in combination with current therapies may be an effective treatment strategy for nearly 90% of breast cancer patients.
A randomized clinical trial found that patients who received corticosteroids after kidney transplantation had similar survival rates compared to those who did not receive them. Corticosteroid use was associated with increased risk of side effects, including acne and bone disease.
A new study found that male fruit flies with the most impressive sexual ornamentation also have super sperm that can outcompete rivals in the post-mating fertilization game. The researchers discovered a strong link between the males' competitive success at passing on their genes even after a female fly has mated with other flies.
UC researchers discovered that stopping autophagy in cancer cells can help treat HER2-positive breast cancer. By blocking this process, cancer cells were unable to develop and grow, and the HER2 protein was altered in a way that prevented its role in cancer development.
A recent UC study found that drugged driving is outpacing drunk driving in the US, with 4.49% of adults reporting marijuana use while driving compared to 8.52% for alcohol. The study also reveals higher rates among sexual minorities, African Americans, and males.
Researchers at the University of Cincinnati studied monk parakeets' behaviors, distinguishing between 'displacements' and 'crowding'. Their computational analysis supported pooling these behaviors, providing a framework for informed decisions in animal behavior research.
Researchers at the University of Cincinnati have developed a new combination therapy that combines radiation therapy with an approved drug to make it more effective in treating head and neck cancer. The study found that the drug alone reduced cancer cell growth by up to 90% and increased the efficacy of radiation treatment by 40%.
Researchers discovered that certain gene pairs are essential for healthy spine development in zebrafish, which can provide insights into human congenital scoliosis. The findings suggest that separating these genes leads to disease development under environmental stress.
A recent study published by the University of Cincinnati identified a shift in caribou movement patterns after the 1970s that coincided with changes in herd size, climate change, and human development. Researchers tracked the movements using antlers shed by female caribou, which contain an isotopic fingerprint of their summer range.
A University of Cincinnati study has found that a mother's stress levels can affect her child's DNA and increase the risk of developing diseases such as asthma, obesity, and autism. The research suggests that maternal stress can alter physiological states in the fetus, leading to adverse health outcomes.
A University of Cincinnati study found that remdesivir permanently stops the activity of an enzyme needed for medication breakdown, increasing toxicity with certain heart and anticancer drugs. The researcher recommends using remdesivir with caution in patients with specific enzymes and in proper dosages.
Researchers found that rural girls in South Africa rely on peer, parental, and environmental factors to prevent pregnancy and HIV/AIDS, rather than modern contraceptive methods. The study highlights the need for more comprehensive education on sexual health beyond HIV/AIDS prevention.
A recent study by University of Cincinnati Cancer Center researchers shows that the pandemic had a negative impact on both preventive screening and patient outcomes for lung cancer. The team found that total monthly CT scans and new patient scans significantly decreased during the COVID-19 period, leading to increased proportion of sus...
Researchers found a significant increase in suicidal behaviors, including ideation, planning, and attempts, between 2015-2018. The study's findings emphasize the importance of addressing mental health issues and developing effective coping skills to prevent suicide. Key risk factors include African Americans, younger adults, sexual min...
University of Cincinnati researchers discovered that certain immune cells respond to immunotherapy by increasing activity in potassium ion channels, allowing them to more effectively target and kill cancer cells. However, patients who do not respond to treatment lack this increased channel activity.
Researchers will analyze human tissue samples to determine genetic predispositions to liver side effects from antiviral drugs. The study aims to identify potential genetic factors and dosing recommendations for safer treatment.
A University of Cincinnati immunologist recommends individuals with contact dermatitis choose facial masks made without elastic to avoid allergic reactions and safely use masks during COVID-19. Cotton-based, knot-tie masks can be a suitable alternative, helping patients manage symptoms and prevent delayed reactions.
A new study from the University of Cincinnati found that only 5.3% of women with kidney failure on dialysis in the US use contraceptives, increasing the risk of unplanned pregnancies. The study emphasizes the importance of family planning and counseling for this high-risk population.
Researchers have developed AI algorithms to decipher waveform bio signals from the heart and brain, identifying individuals at risk for cardiovascular death. By analyzing these signals during sleep, they can detect hidden signatures indicating homeostatic imbalance or early onset of potentially fatal diseases.
Researchers have identified a new class of sedatives that could enhance the effectiveness of radiation and immunotherapy treatments for metastatic melanoma, reducing toxic side effects. In animal models, these treatments resulted in improved infiltration of immune cells into tumors, shrinking or eliminating cancerous growths.
The University of Cincinnati researcher is studying the role of a muscle protein in the development of distal arthrogryposis, a rare skeletal muscle disorder. The protein in question, myosin binding protein-C, has been found to be essential for muscle formation, function, and regulation in both heart and skeletal muscles.
Harshita Kumari, a UC pharmacy faculty member, has received a research grant to study the properties of eco-friendly surfactants. The project aims to characterize these molecules in terms of their sustainability and environmental safety compared to leading benchmark products.
A University of Cincinnati cardiologist is developing a smartphone app to deliver targeted COVID-19 information and education to Black communities. The app aims to address the disproportionate impact of COVID-19 on African Americans, with input from focus groups in three states.
Scientists have sequenced the genome of New World screwworms, identifying ways to slash populations by targeting specific genes. This research could lead to a more efficient biological barrier system to prevent the species from moving north and causing massive livestock losses.
A University of Cincinnati biologist found that even small concentrations of estrogen in water can lead to a gender ratio imbalance and smaller fish populations. The study used least killifish, which have live young, and found that exposure to estrogen resulted in more females than males.
The ancient Maya created a water filtration system nearly 2,000 years ago, using crystalline quartz and zeolite to remove harmful microbes and toxins from drinking water. This innovative system would still be effective today.
Researchers at UC have identified metabolic fingerprints that distinguish cancers from nonsmokers compared to smokers, providing important steps toward new and better therapeutic strategies for kidney cancers in both smoking and nonsmoking populations. The study reveals a separate metabolic subtype of kidney cancer with different weakn...
A University of Cincinnati researcher is conducting a study on pharmacogenomics and opioid addiction. The goal is to identify genetic markers associated with OUD and compare them between patients who have and don't have the condition.
A new report by the University of Cincinnati suggests that large majorities of American news audiences care about climate change and want more information on the topic. The study found that fewer than 20% of Americans in these news audiences feel 'very well informed' about climate change.
Researchers at University of Cincinnati discover sphingosine, a natural element, can interfere with SARS-CoV-2 binding to human cells, preventing infection. The study suggests sphingosine could be used as a nasal spray to prevent or treat COVID-19.