A balance test that measures an individual's ability to stand on one leg for 10 seconds can predict mortality risk in middle-aged and older adults. Researchers found that those who failed the test had a significantly higher risk of death from any cause within the next decade, with an absolute difference of nearly 13%.
Researchers have developed innovative tests for multiple chemicals using plant-based molecules that can detect synthetic cannabinoids and banned pesticides. The system uses a simple and inexpensive approach to quickly signal the presence of nearly 20 different chemicals.
A new study found that the 2021 heat wave caused widespread death among shellfish due to a combination of low tides, high air temperatures, and location. The research team analyzed hundreds of field observations and found that some species fared better than others in terms of survival.
A new nanosensor developed by Chinese scientists can detect mesna, a regional antidote for urinary system protection, in real-time with high sensitivity and selectivity. The platform features an upconversion-based sensor that eliminates background interference and offers a simple and reliable strategy for clinical drug monitoring.
Researchers found that using advanced image-guided technology didn't lead to better outcomes for patients, but rather put them at higher risk of strokes. The study suggests that a simpler approach may be more effective in treating atrial fibrillation.
The USPSTF recommends against using beta carotene or vitamin E supplements to prevent cardiovascular disease (CVD) or cancer. Inflammation and oxidative stress play a role in both CVD and cancer, but dietary supplements have shown anti-inflammatory and antioxidative effects, leading to proposals for their use as preventive measures.
Dermatitis will be published bimonthly in print and online formats with open access options. The Journal focuses on contact, atopic, occupational, drug-induced dermatitis and environmental dermatitis.
The WVU program trains next generation of toxicologists to collect, analyze air samples from mining, fracking sites, using the university's Inhalation Facility. Students will work with preceptors from various fields to investigate health effects of inhaling toxicants.
Scientists at Chung-Ang University have pioneered a novel method for controlling microdroplet motion on solid surfaces using near-infrared light. This approach allows for more precise control than traditional thermal techniques and opens up new possibilities for applications in microfluidics, drug delivery, and self-cleaning surfaces.
A study by UC San Diego's Rady School of Management found that people are more likely to hurt others when they believe it is morally right, rather than for personal benefit. The research suggests that laws and punishments may not be effective deterrents if they don't address the underlying moral motivations behind violent behavior.
The SciComm Identities Project is a five-year initiative creating fellowships for tenure-track faculty members from diverse backgrounds, focusing on climate change issues like energy, water, and agriculture. The program aims to train science communicators from marginalized communities in environmental science.
Researchers have developed a way to fine-tune CAR T cell therapy to strike a balance between safety and efficacy, reducing the risk of severe side-effects. The new approach enables customisation of potency levels for individual patients, broadening its potential as a first-line treatment.
Researchers at Leibniz-HKI found that lactic acid bacteria nourish intestinal cells, promoting bacterial growth and adapting Candida's metabolism to make it less infectious. This balance restores a healthy state and prevents fungal infections.
A population-based study found that patients with estrogen receptor-positive breast cancer who experienced hot flashes while on adjuvant hormone therapy had worse outcomes and a higher risk of early treatment discontinuation. The study suggests that managing side effects may not be enough to prevent treatment discontinuation, highlight...
A study evaluating discharge data from five states found that postoperative mortality rates in children undergoing tonsillectomy were associated with recognized risk factors for complications. The analysis revealed that comorbidities, such as heart disease and respiratory conditions, significantly increased the risk of mortality.
Researchers at Osaka Metropolitan University observed unprecedented collective resonance motion in chiral helimagnets, allowing a significant increase in current frequency bands. This phenomenon enables a boost in frequencies beyond 100 GHz with relatively weak magnetic fields, making these materials promising for 6G technology.
A UC San Diego study suggests COVID-19 rebound symptoms after taking Paxlovid are likely caused by insufficient drug exposure, not resistance or impaired immunity. The study found the virus remained sensitive to the drug and no relevant mutations were detected.
Chronic kidney disease and glaucoma have been found to share common risk factors such as diabetes and hypertension, leading to a higher risk of developing both conditions. The study also reveals that patients with glaucoma are more likely to develop chronic kidney disease over time.
A novel enzyme-free strategy was developed to detect organophosphorus pesticide residues like glyphosate in agricultural products. The new approach uses a ratiometric fluorescence sensor that can visualize and quantify glyphosate residues with high sensitivity, allowing for rapid detection and monitoring of pesticide residues.
A novel technique can rapidly detect chiral molecules in complex gas mixtures, identifying fake perfumes and damaged plants. This approach has vast potential for agriculture, quality control of perfumes, and monitoring plant health.
A MedUni Vienna study team has identified a specific subtype of macrophages as a protective function against fibrosis in non-alcoholic fatty liver disease. TREM2-positive macrophages have been shown to prevent fat accumulation, inflammatory processes and progression to liver fibrosis.
Foodomics is a data-driven approach to characterize and quantify biomolecules in food, improving wellbeing. The application of omics technologies like genomics, transcriptomics, proteomics, and metabolomics enables the creation of a comprehensive food composition database.
A new study reveals that acids in sugar-free beverages can erode tooth enamel, posing a risk to dental health. Flavored sparkling waters also showed signs of erosion, although less than sugar-containing and sugar-free sodas.
Researchers from Japan developed a new model to assess mangrove forest productivity, which is influenced by environmental factors such as sea surface temperature and salinity. The model uses satellite data to estimate productivity and performed better than traditional terrestrial models.
Researchers discovered how Mycobacterium tuberculosis can evolve efficiently by forming complex biofilms due to genetic mutations. The study sheds light on the bacterium's robustness and identifies potential vulnerabilities for developing more effective treatments.
Researchers at Rensselaer Polytechnic Institute developed an accessible way to make N95 face masks that can kill viruses and bacteria on contact. The antiviral masks use a simple process with widely available tools, reducing plastic waste by allowing for longer wear.
Researchers at McGill University have discovered microbes that can survive in conditions similar to those on Mars. These microorganisms thrive in extremely salty, cold, and oxygen-free environments by eating and breathing simple inorganic compounds. The study provides insights into the possibility of life on Mars.
A team of scientists has developed a complex tissue platform that can restore damaged rotator cuffs through 3D-bioprinting. The platform, which includes stem cells and tissue-specific extracellular matrix bioink, regenerates tissues and improves shoulder function in animal models.
A recent study found that socioeconomic disparities in obesity among US adolescents have significantly increased over the past two decades. The findings suggest that adolescents from lower-income backgrounds are more likely to be obese, highlighting a pressing public health concern.
Wistar scientists have identified a novel therapeutic approach that inhibits the gene KDM5A, which improves immune cell infiltration and attack on tumors. This approach has shown promising results in both in vitro and in vivo studies, including reduced tumor burden and improved survival rates in mice with ovarian cancer.
Researchers found that low-energy helium plasmas pre-exposure creates nanostructures on material surfaces, reducing deuterium plasma-driven permeation flux. Theoretical calculations confirm that surface protrusions and near-surface helium bubbles reduce hydrogen isotope penetration through the material.
Researchers develop BPAWR-SACM process to generate designable spatially coherent wide-band radiation without resonant cavity. The technique amplifies centered non-absorption band with gain up to 26.02 dB, enabling frequency modulation in visible light range.
The American Heart Association warns that e-cigarette use in adolescents can lead to stunted lung development and altered cardiovascular systems, increasing the risk of heart disease over time. Long-term exposure to e-cigarette aerosols has been linked to increased blood pressure, impaired blood vessel function, and arterial stiffness.
A new AI-powered mental health application, FuturSelf, uses machine learning to identify the shortest path to mental stability. The system offers personalized recommendations for improving long-term well-being.
Researchers constructed a synthetic stub lattice in two coupled rings of different lengths, observing flat bands, band transitions and mode localization. This experimental demonstration enables dynamic control of light and may pave the way for future applications in optical communications.
Researchers developed a new testable model to improve understanding and treatment of metabolic diseases. The model integrates various aspects of cell signaling, addressing how calorigenic nutrients activate cells.
Researchers found that hackmanite's structural breathing allows it to change color indefinitely due to sodium atoms moving inside a zeolitic cage. This property enables various applications such as UV monitoring and X-ray imaging.
Researchers at KIST have developed a new polymer additive material to prevent aggregation in photoactive layers of large-area organic solar cells, improving performance and stability. The technology achieves a 14.7% module efficiency, a 23.5% increase compared to conventional systems.
The American Society for Biochemistry and Molecular Biology has honored 14 scientists with its annual awards, recognizing their outstanding contributions to the field. The recipients will give award lectures at the society's annual meeting in March, and each award includes a cash prize, plaque, and transportation expenses.
A new study has found that a medication used to treat multidrug-resistant tuberculosis is associated with favourable pregnancy outcomes and high treatment success. The study examined the experiences of 275 pregnant women living with multidrug-resistant tuberculosis in five countries, finding that 73.2% gave birth to healthy babies.
The American Gastroenterological Association has released new clinical guidelines outlining a personalized approach to treating irritable bowel syndrome (IBS) patients. The guidelines recommend prioritizing lifestyle modifications and dietary changes, such as increasing fiber or following the low-FODMAP diet, before seeking advanced tr...
The study investigates relative gaps in COVID-19 vaccination between ethnic groups, finding significant disparities in vaccination rates. Researchers use different population estimate methodologies to analyze the resulting population risk among people in New Zealand.
Researchers at MIT have developed a method to enable quantum sensors to detect any arbitrary frequency without losing nanoscale spatial resolution. The new system, called a quantum mixer, injects a second frequency into the detector using microwaves, enabling detection of signals with desired frequencies.
Researchers used LiDAR technology to create high-resolution scans of log 'castles' that house Western Spiny-tailed Skinks, revealing what makes them suitable habitats. The study aims to help conservation efforts by replicating these 'log castles' and managing introduced predators in mining landscapes.
A team of scientists has developed a novel computational approach to analyze DNA sequences of thousands of bacteria, revealing previously unknown gene clusters responsible for producing metabolites of interest. The study highlights the potential of these bacterial compounds in treating colon cancer and improving treatment options.
Researchers found that walking enhances performance on cognitive tasks in 14 participants by increasing frontal brain function, while 12 others showed no improvement. This discovery highlights the flexibility of a healthy brain and has implications for understanding aging and neurological disorders.
Researchers used X-ray crystallography to reveal the structure of HIV-1 matrix protein at 2.1 angstroms resolution, advancing understanding of viral assembly and envelope protein incorporation. The study showed that molecular details at this level can help develop new therapeutic agents inhibiting HIV-1 assembly and virus production.
Researchers studying Mexico City's 700-year history highlight the need for democratic adaptation decisions and prioritizing climate justice over technological innovation. The city's complex water management system, built on an island in a saline lake, demonstrates trade-offs between flood control and urban development.
The European Society of Gynaecological Oncology and four international medical societies have published consensus statements on the treatment of pre-invasive vulvar lesions. These guidelines highlight the need for specific attention to these lesions, which can cause symptoms such as burning and itching, and may progress to invasive can...
A study by Rice University finds that agricultural nitrogen emissions cause substantial damage to air quality, human health, and the climate. The researchers quantified emissions from fertilized soils over three years and found that ammonia had a much larger impact on damages than nitrogen oxides and nitrous oxide.
Researchers from Hefei Institutes of Physical Science found that singlet oxygen plays a crucial role in synergistic antimicrobial mechanism with other ROS generated by cold atmospheric plasma. This study improves understanding of fungicidal mechanism and provides theoretical guidance for applications of plasma technology.
Researchers discovered that sex differentiation in Bursaphelenchus nematodes occurs through a stochastic regulation mechanism, dependent on random events. This finding may help develop population engineering strategies for controlling nematode populations and mitigating plant diseases.
Researchers investigated the cell adhesion behavior on spider silk fibers, films, and nanofibers. The study found that native spider silk exhibits superior properties for medical use, preventing blood clots and enduring repetitive loading and unloading.
Researchers developed zinc oxide/graphene oxide nanocomposites to detoxify cadmium poisoning, which competitively inhibited cellular Cd uptake and promoted Cd excretion. The compounds showed excellent detoxification capacity and biosafety, holding promise for treating occupational exposure populations.
Scientists have discovered a way to harness animals' olfactory ability to protect endangered plants and animals by masking their scent, disguising it, or spreading similar scents. This method is more effective, sustainable, and animal-friendly than traditional deterrents like fences and lethal control methods.
A new study reveals that COVID-19 variants are formed in chronic patients with weakened immune systems, who experience prolonged infections. This leads to the accumulation of mutations, similar to those found in severe illness variants.
Researchers found that climate change is shifting the risk of human-wildlife conflicts in Thailand, with northern areas more vulnerable to elephant-human interactions. The study suggests that as natural habitats become fragmented, conflicts may intensify in rural areas where agriculture relies heavily on land.
A new muscle biopsy test could lead to an earlier diagnosis of amyotrophic lateral sclerosis (ALS), a progressive disease affecting nerve cells in the brain and spinal cord. The test targets transactive response DNA-binding protein 43 (TDP-43) accumulation, which may be a biomarker for early ALS diagnosis.
Researchers discovered PDE5 inhibitors can reverse chemotherapy resistance by targeting cancer-associated fibroblasts, potentially shrinking oesophageal tumours more than chemotherapy alone. The treatment is already proven to be safe and well-tolerated, with promising results in a phase I/II clinical trial.
A systematic review of 84 studies found insufficient evidence that multivitamins or supplements can prevent cardiovascular disease and cancer in healthy adults. In contrast, diet and exercise are key to maintaining health. Whole fruits and vegetables contain a mixture of vitamins, phytochemicals, fiber, and other nutrients that act syn...