Gram-negative bacteria rely on cell wall to synchronize outer membrane building, but a new study identified 'old' peptidoglycan as the key factor controlling this process. Disrupting this mechanism makes Gram-negative bacteria vulnerable to targeted antibiotics.
Scientists have discovered a new multiplanet system about 33 light-years from Earth, featuring two rocky, Earth-sized planets. The inner planet orbits every 2.8 days and is twice as massive as the Earth, while the outer planet orbits every 5.7 days and is three times as massive.
Two new species of giant dwarf crocodiles, Kinyang mabokoensis and Kinyang tchernovi, were discovered in East Africa between 18 million and 15 million years ago. The ancient forms were massive predators that likely posed a significant threat to human ancestors.
Researchers from the University of Georgia Laboratory of Archaeology have discovered evidence of 'council houses' on the Cold Springs site, dating back to around 500 A.D. The findings indicate that democratic institutions associated with collective governance were present in the Americas for at least a millennium before European contac...
A new study published in mSystems demonstrates that a surface sampling method can detect SARS-CoV-2 RNA on surfaces, improving environmental surveillance in public health labs.
A study of over 100,000 individuals found that those who sat for six to eight hours a day had a 12-13% increased risk of early death and heart disease, while those who sat for more than eight hours daily increased the risk by 20%. High amounts of sitting time were associated with increased risk of cardiovascular disease globally.
New Zealand military veterans experience high levels of anxiety and depression, but also struggle with pain and mobility. Factors such as age, deployment, psychological flexibility, and sleep quality are associated with better health outcomes.
A new study finds that the quality of dog-owner relationships is similar between Canadian-born dogs and internationally sourced dogs. Owners reported equal satisfaction, attachment, and problematic behaviors, suggesting owner attitudes play a greater role than dog characteristics.
The Safeguard project recommends improving pollinator knowledge, tackling causes of decline, and raising awareness to reverse the 2030 pollinator loss objective. European Commission's public consultation gathered views on strengthening the current framework on wild pollinators.
Astronomers used the Gemini South telescope to capture high-resolution images of dusty disks around 44 young massive stars. The survey found that smaller star-mass systems have ringed structures, while more massive systems do not.
African countries face a growing cancer burden, with an estimated 2.1 million new cases and 1.4 million related deaths expected by 2040. Insufficient healthcare resources and infrastructure will likely overwhelm capacity levels, delaying screenings and limiting treatment options if action is not taken.
A collaborative initiative aims to establish common protocols for assessing and comparing diffuse optics systems used in medical diagnosis. The study presents the results of a multi-laboratory comparison of 12 institutions and 28 systems, proposing simple numeric values for easy comparison across instruments.
A pilot study found that drinking either alcoholic or non-alcoholic lager daily increased the diversity of gut microbes in healthy men, potentially reducing chronic disease risk. The researchers suggest that non-alcoholic beer may be a healthier choice due to its lower alcohol content.
Researchers compared the accuracy of rapid antigen tests with RT-PCR in detecting SARS-CoV-2 infection among college athletes during the Omicron variant. Rapid antigen tests showed high sensitivity but lower specificity, while RT-PCR demonstrated higher specificity and sensitivity.
Two fossil skulls of a 12- to 15-million-year-old hyena from China suggest the animal was on its way to becoming an insectivore, like the modern aardwolf. The fossils show characteristics intermediate between those of bone-cracking hyenas and termite-eating aardwolves.
Scientists at the University of Oxford have created a new type of computing processor that uses light to process information, achieving speeds faster than traditional electronics. By leveraging multiple polarisation channels, the researchers increased computing density by several orders of magnitude, paving the way for more efficient p...
Adult flu vaccination rates declined in states with low COVID-19 vaccination rates, indicating a potential link between the two. The study found that factors causing low COVID-19 vaccination behaviors also led to declines in flu vaccination rates.
A new study suggests that losing a grandmother may have a significant impact on adolescent boys, leading to a 50% increase in depressive symptoms. The researchers also found that the loss of a grandparent can be a risk factor for teen depression and other negative outcomes.
A new University of California, Davis study found that implementing an educational philosophy called a mindset intervention raised grades among underachieving students. The study, which included nearly 2,000 ethnically diverse sixth and seventh grade students, showed that early intervention with teachers and training on malleable intel...
A study found that COVID-19 leads to progressive cholestasis, cholestatic liver failure, and secondary sclerosing cholangitis in 15% of patients with pre-existing liver disease. These patients often require intensive care and may experience irreversible bile duct damage.
A new study published in Blood Advances reveals significant disparities in end-of-life care for individuals with hematologic malignancies living in rural areas versus metropolitan regions. Rural residents are less likely to receive hospice care, instead often dying in nursing facilities or at home without palliative care.
The COVID-19 pandemic significantly impacted patient accruals in oncology clinical trials, with a 46% decline early on. However, the recovery has been progressive, with newly activated clinical trials increasing by 467 from 2019 to June 2021.
Asteroid Psyche's varied surface suggests a dynamic history, with metallic eruptions, asteroid-shaking impacts, and a lost rocky mantle. The new maps hint at the asteroid's ancient core, which could be composed of silicate-rich material that has since disappeared.
Researchers from the University of Tsukuba found that Synapsology, a game-like dual-task exercise, helps maintain or improve cognitive and physical abilities in older adults aged 85-97. The study, published in Alzheimer's & Dementia, suggests that this cost-effective intervention can have a societal impact.
A new review paper has proposed a framework for advancing the application of xenotransplantation, a potential solution to the organ shortage. The study discusses innovations and advances in transplanting animal hearts into human subjects, with a focus on overcoming challenges and barriers.
A new irrigation decision support system enables growers to practice more efficient irrigation by analyzing climate predictions, humidity sensors, and irrigation meters. This system allows for optimal watering schedules and reduces water consumption by up to 20% through controlled deficit irrigation strategies.
Scientists have identified 21 common DNA faults that occur in cancer, which can guide doctors to targeted treatments. The AI algorithm, inspired by Netflix's content recommendation system, categorizes genomic data to predict cancer behavior and outcomes.
A new study from Keck School of Medicine of USC suggests that willingness to give away money may be linked to the earliest stages of Alzheimer's disease. Participants who gave more money scored significantly lower on cognitive tests known to be sensitive to Alzheimer's disease.
A study found that older men, especially dog owners, coped better during the COVID-19 pandemic than those who experienced the HIV/AIDS pandemic. Pet companionship reduced feelings of loneliness and provided a sense of purpose.
A team of researchers from the University of Cologne identified a possible key enzyme that enables algae-eating protists to dissolve algal cell walls. The study, published in Current Biology, reveals new insights into the molecular toolkit used by these organisms to interact with their prey.
Researchers have developed a test that measures blood levels of ceramides, a waxy substance similar to cholesterol, to predict diabetes remission in gastric bypass surgery patients. The study found that individuals with low ceramide levels prior to surgery had a higher likelihood of achieving diabetes remission two years later.
A new study found a close link between ageism and poor physical and mental health in older adults. Those with more health concerns experienced higher rates of everyday ageism, including internalized and interpersonal forms.
A study analyzing fecal samples from COVID-19 patients found that those with healthy gut microbiota had higher diversity and SCFAs, reducing chronic symptoms. Probiotics and supplements may alleviate symptoms and promote prognosis in these patients.
Researchers have developed a framework to analyze chromosomal instability in human cancers, characterizing 17 different types of signatures. These signatures can predict how tumors respond to drugs and help identify future drug targets. The discovery aims to improve survival rates for millions of cancer patients worldwide.
A new study published in Science Translational Medicine reveals that consecutive molecular modifications of the androgen receptor can contribute to drug resistance in prostate cancer. Researchers identified a potential treatment approach using an ACK1 inhibitor to block this resistance.
The University of Tennessee Institute of Agriculture's REM Lab uses eye-tracking technology to study consumer preferences, product evaluations, and behavior. The lab aims to develop new solutions in multiple agricultural industries, with potential applications in marketing design and product displays.
Seagrass meadows are a crucial fishing ground for millions of households in the Indo-Pacific region, providing reliable access to fish and other animals. Research reveals that households with lower income rely more heavily on seagrass due to its proximity and accessibility.
The US Preventive Task Force's revised guidelines have increased the proportion of African Americans screened for lung cancer, a move expected to lead to more lives saved. The study, published in JAMA Network Open, analyzed data from over 800 patients and found that those eligible under the new criteria had a significantly higher rate ...
Researchers found higher AR signaling and better response rates for female patients treated with BRAF/MEK inhibitors. Blocking the AR improved response to BRAF/MEK targeted therapy in both males and females.
A state health department's swift action halted a nursing-home outbreak of drug-resistant Acinetobacter baumannii. Improved hand hygiene, enhanced environmental cleaning protocols, and colonization screening helped contain the spread of the organism, with no additional cases detected after implementation of infection control recommenda...
A study from Cincinnati Children's Hospital Medical Center found that early antibiotic use disrupts the developing immune system of newborns, increasing risks of severe pneumonia and life-long health issues. Fecal transplants may offer a solution to mitigate these effects.
Researchers develop new method to synthesize two-dimensional monolayer polymeric fullerene, a unique member of the carbon material family. The material exhibits interesting properties, including anisotropic behavior and moderate bandgap, making it a potential candidate for electronic devices.
Researchers at the University of Colorado Boulder and NIST have successfully demonstrated reading out signals from superconducting qubits using laser light, preserving the qubit's information. This breakthrough could enable the creation of a quantum internet, allowing for secure communication over long distances.
Homa Alemzadeh's research aims to develop safety monitoring tools for robotic surgery, enabling better training for surgeons and increasing the availability of less-invasive procedures. Her work has the potential to improve patient outcomes in underserved rural communities.
A new technique has identified previously hidden protoclusters that could reveal new details about galaxy evolution. The ancestors of large galaxy clusters were found to be hiding in plain sight, with some protoclusters harboring unseen galaxies that evolved differently.
Menopause is often perceived as a hormone deficiency, but experts argue this can lead to negative expectations. Instead, a more nuanced approach emphasizes the positive aspects of menopause, such as freedom from menstruation and reduced symptoms. Normalizing ageing and celebrating women's strengths can also improve experiences.
Heidelberg University researchers have identified a key protein HYPK that regulates N-terminal acetylation, prolonging plant protein life and enhancing drought resistance. This mechanism appears to be ancient, retained across various organisms.
Researchers found that states implementing Medicaid expansion saw a slower increase in suicide rates compared to those that didn't expand access. The study estimated that 1,818 suicides were averted between 2014 and 2018, with improved mental health care playing a crucial role.
Indiana University researchers have discovered the world's brightest-known fluorescent solid materials, called SMILES, which can transform liquid materials into stable crystalline solids with unprecedented brightness. The grant will help advance research on SMILES to improve existing technologies and create new ones.
Researchers have identified two broadly neutralizing antibodies that can effectively neutralize all SARS-CoV-2 variants, including Omicron BA.1 and BA.2 subtypes. The antibodies, Cv2.1169 and Cv2.3194, were found to be fully active against Alpha, Beta, Gamma, and Delta variants.
Researchers draw inspiration from insect intelligence to create more efficient and robust AI for small autonomous robots. Advances in biology and technology enable fine-grained investigations of insect brains, leading to faster energy efficiency and speed in sensing and neural processing.
A pan-Canadian study found that prescribing buprenorphine-naloxone at home is as effective as traditional methadone treatment in reducing opioid use. The flexible model of care offers improved access and autonomy for individuals with opioid use disorder. With over 270 participants, the OPTIMA study suggests a new approach to treating t...
A Cornell University research team used AI to detect eelgrass wasting disease at nearly three dozen sites along the West Coast. The study found that warmer-than-normal water temperatures are associated with eelgrass wasting, regardless of region. Eelgrass is a vital coastal species for fish habitat and biodiversity.
Researchers identified a molecule called Lac-Phe that suppresses food intake by 50% in diet-induced obese mice. Lac-Phe also improves glucose tolerance and reduces body weight, paving the way for potential exercise pills to treat obesity and related conditions.
A study by Queen Mary University of London found that 26% of patients with asthma are overusing rescue inhalers, which can lead to poor asthma control and increased risk of severe attacks. By reducing SABA overprescribing, hospitals can see a 70% decrease in asthma-related hospital admissions.
Researchers studied miniature frogs from the genus Brachycephalus and found that their small vestibular system prevents them from maintaining balance. The tiny frogs can jump but struggle to control their trajectory mid-leap.
A study found that a methionine-deficient diet alters gene expression and DNA methylation in liver cells, increasing the risk of non-alcoholic fatty liver disease. A methionine-supplemented diet had the opposite effect, reducing the risk of liver damage.
A study of 105,000 participants from 21 countries found high amounts of sitting time were associated with increased risk of all-cause death and cardiovascular disease. This association was particularly strong in low-income and lower-middle-income countries.
A large clinical trial found that treating high-grade squamous intraepithelial lesions (HSIL) reduces the risk of anal cancer in people with HIV. The study showed a 57% reduction in anal cancer cases after treatment, highlighting the importance of screening and treatment for HSIL in this population.
A new study led by UCSF found that routine screening for and removal of precancerous anal lesions can significantly reduce the risk of anal cancer. The study, known as ANCHOR Study, showed a 57% reduction in anal cancer among people with HIV who underwent treatment for high-grade squamous intraepithelial lesions (HSIL).
Researchers have developed a unique 3D printed system to harvest mesenchymal stem cells from bioreactors, which can be used for various treatments. The system combines microfluidics and 3D printing to process adult stem cells, potentially making stem cell therapies more widely available.
A new standardized method for measuring calcium carbonate on ocean floors can help researchers compare coral reef health globally. The 'how-to' guide enables the collection of comparable data from coral and oyster reefs worldwide, providing insights into the impacts of climate change and human activities.
Patients with diabetes who participate in a free Annual Wellness Visit are 36% less likely to need an amputation, according to a new study from the University of Virginia School of Medicine. This preventive care service helps detect foot complications earlier, reducing the risk of amputations.
Ancient DNA analysis reveals that an epidemic devastated a local community in Kyrgyzstan in 1338 and 1339, linked to the Black Death. The study suggests that the Black Death's ancestor originated in Central Asia, close to Lake Issyk Kul.
A team of researchers from SLAC National Accelerator Laboratory developed a mathematical technique using machine learning concepts to model a magnet's previous states. This approach eliminates the need to reset magnets and results in immediate improvements in accelerator performance.
A new analysis suggests that BP's reputation declined after the 2010 Deepwater Horizon accident, but its long-term stock market returns were not significantly affected. The study found no decline in the reputations or stock prices of other oil firms.
An analysis from Rutgers researchers highlights that different vaccine allocation strategies may be more effective in minimizing COVID-19 deaths in low-income countries. The experts suggest considering factors such as socioeconomic realities, cultural values, and life expectancy when making decisions.
Researchers found that nanocontacts remain solid despite vibrations, due to reversible rheological steady state. This phenomenon, previously thought to be a liquid, is actually caused by the movement of internal micro-surfaces.
Researchers at Case Western Reserve and University of Washington develop AI-3D collaboration to gain insights into highly aggressive prostate cancer. The collaboration aims to provide a new view and understanding of prostate cancer cells using light sheet microscopy.
A new technique, SA-MDP, has been developed to solve the sensitive association rule problem in data mining. It uses a customized particle swarm optimization algorithm to balance data utility and privacy, and introduces particle splitting and preprocessing mechanisms to improve exploration and speed.
A new study found that 64% of adults who had contact with the child welfare system as children achieve excellent mental health, highlighting resilience and factors associated with flourishing. Chronic pain, major depression, and social isolation hinder optimal mental health.
A new study published in PLOS ONE found that dog-assisted interventions can significantly reduce stress levels in elementary school children, both with and without special needs. The research used salivary cortisol levels to track the effects of dog interactions on stress levels, revealing a decrease in cortisol levels after dog sessions.
Researchers at Chalmers University of Technology have invented a material that uses electrical signals to separate biomolecules, paving the way for efficient production of biomedicines. The material's ability to function in biological fluids with buffering capacity enables remote-controlled drug release and reduces energy consumption.
A new analysis published in JAMA Psychiatry shows that brief suicide prevention interventions delivered in healthcare settings drastically underreport the strategies needed for successful implementation. On average, about 85% of these strategies were missing from published reports.
Climate-related events and air pollution disproportionately affect socially and economically disadvantaged children, exacerbating health issues such as preterm birth, respiratory illness, and malnutrition. The authors emphasize the need for simultaneous adaptation and mitigation strategies to protect children's health.
Researchers identified DNA damage-inducible transcript 4 (DDIT4) as a critical factor regulated by histone deacetylase 4 (HDAC4) in skin aging. Overexpression of HDAC4 rescued cells from senescence, while DDIT4 overexpression reversed changes associated with aging.
Youth substance use declined during the COVID-19 pandemic, as teens had limited access to peers and substances due to stay-at-home orders. This reduced risk of substance use is attributed to increased social isolation from peers, which may have a negative impact on mental health.
Research on two worm phyla provides clues on how separate sexes originated and evolved in animals. The study characterizes the evolution of sex chromosomes in flatworms and roundworms, revealing that their diversity is a result of different combinations of genetic elements.
Researchers at EMBL discovered how messenger RNA molecules bind to and regulate the enzyme ENO1, which breaks down glucose. This riboregulation process can determine cell growth and differentiation, with potential implications for understanding cancer.
Researchers warn policymakers that inadequate charging networks can derail EV adoption efforts, particularly if floods disrupt charging infrastructure, affecting not just the immediate area but also farther away. Strong public confidence in the network is crucial for long-term adoption and meeting carbon reduction targets.
A novel study published in the Canadian Journal of Cardiology demonstrates that Nordic walking provides greater long-term improvements in functional capacity compared to high-intensity interval training and moderate-to-vigorous intensity continuous training. Nordic walking engages core, upper, and lower body muscles, resulting in a sig...
Researchers from Tel Aviv University and the Hebrew University discovered charcoal remnants from olive trees at the Chalcolithic site of Tel Zaf, indicating intentional cultivation around 7,000 years ago. This marks the earliest evidence of domestication of a fruit tree worldwide.
A recent study found that higher exposure to air pollution is associated with increased functional brain connectivity among several brain regions in preadolescents. The findings also identify the first years of life as the most sensitive period for exposure to air pollution, with black carbon particles being the most associated polluta...
Scientists at Max Born Institute demonstrate ultrafast emergence of all-optical switching by generating a nanometer-scale grating through interference of two pulses in the extreme ultraviolet spectral range. The researchers identify an intensity ratio as a fingerprint observable for AOS in diffraction experiments.
The June 2022 issue of GEN Biotechnology features groundbreaking research on adenine base editing, which could lead to more precise and safer genetic therapies. Additionally, the journal explores racial disparities in biotech leadership and advocates for improving diversity, equity, and inclusion.
The device can instantly recognize what it sees, like automatic descriptions of pictures taken by a camera or phone, and outperforms the eye in the number of wavelengths it can see. It's uniqueness comes from its ability to integrate three different operations into one, making it many times faster than current technology.
Scientists have found evidence for a young and extremely powerful neutron star, dubbed VT 1137-0337, in a dwarf galaxy 395 million light-years from Earth. The pulsar is thought to be as young as 14 years old and has the strongest magnetic field of any known object.
A recent study published in the Journal of Alzheimer's Disease found that poor sleep among African Americans is associated with lower cognitive function, including attention and executive function. The study suggests that improving sleep health may support prevention of Alzheimer's disease and related dementias.
A telephone survey of over 1.4 million US adults found modest increases in clinically significant anxiety and depression during the first year of the pandemic. Key population segments, such as first responders, may have experienced more substantial increases.
Researchers have created a new classification system for coexisting mangrove-coral habitats, identifying four distinct types: lagoons, creeks, fringe areas, and under the mangrove canopy. These habitats are diverse, with about 130 species of corals living in them, and are crucial for coral survival.
Researchers used ALMA to study 30 Doradus, a large star-forming region in the LMC, and discovered that gravity is shaping molecular clouds despite intense stellar feedback. The observations revealed a pattern of highly organized filaments, which are likely an important step in the process of star formation.
Researchers at Politecnico di Milano developed a new nanomaterial with a superfluorinated gold cluster, exhibiting unique optical and catalytic properties. The findings have potential applications in precision medicine and the green transition, including diagnostic and therapeutic applications and efficient production of green hydrogen.
USC Viterbi School of Engineering researchers introduce platinum as a non-toxic catalyst to transform toxic aldehydes into harmless carboxylic acids in wastewater. The breakthrough enables the production of clean and reusable water, addressing growing concerns about water shortages and regulatory requirements.
A UC San Diego longitudinal study found that most COVID-19 long-haulers continue to suffer from neurological symptoms six months after infection, with memory impairment and decreased concentration being the most prevalent. Researchers identified a new subgroup with advanced symptoms, including tremor and difficulty balancing.
A groundbreaking study using cellular barcoding in mice reveals that blood cells originate from two independent sources: hematopoietic stem cells and embryonic multipotent progenitor cells. These findings have significant implications for understanding blood cancers, bone marrow transplant, and the aging immune system.
A recent study published by the American Academy of Neurology found that brand-name epilepsy drugs experienced a significant price hike between 2010 and 2018, with costs rising by 277% compared to generic alternatives, which decreased in value by 42%. This shift in pricing has major implications for patients and healthcare systems.
A new analysis by University of Pittsburgh scientists demonstrates that institutional racism, rather than race-based biology, worsens asthma severity in Black people. The study links discriminatory lending practices from the 1930s to long-term environmental and health inequities, particularly in historically redlined neighborhoods.
Astronomers use Gemini South Telescope to study how planet formation differs in low-mass star systems, discovering large rings composed of tiny dust grains around some stars. The team also finds a potential new exoplanet candidate orbiting a young star with a mass similar to Jupiter.
A recent study published in the New England Journal of Medicine found that COVID-19 vaccine immunity against new infection appears to wane rapidly, whereas people with a prior-infection were moderately protected from Omicron. Natural immunity provided strong and durable protection against severe illness.
A recent study of Polish teens reveals that even teachers trying to counteract gender stereotypes in the classroom can end up reinforcing them. The research observed 34 classes and found that teachers' responses to students' stereotypical behavior often perpetuated these same biases.
Researchers found that mesenchymal-like cells with enhanced contractility guide epithelial cancer cell migration through heterophilic N/E-cadherin complex formation. Inhibiting this complex reduces interaction between mesenchymal-like and epithelial cells, preventing tumor invasion.
A UC Riverside genetic discovery found that mosquitoes lack the primary ecdysone transporter, allowing researchers to develop a mosquito-specific insecticide. This breakthrough could help control Zika, dengue, and other virus-carrying mosquitoes without harming beneficial insects.
A systematic review and meta-analysis found that physical activity can boost the body's immune response to influenza vaccination. The study analyzed data from over 100,000 individuals and concluded that regular exercise may provide better protection against the flu.
Researchers at Kyoto University's Institute Advanced Study of Human Biology (WPI-ASHBi) have gained new insights into how totipotency is programmed in germline cells. They found that DNA methyl groups are removed and DNA strands are unwound to create a 'clean slate' for embryo development, while also building insulation to prevent earl...
Researchers found that humans can better locate targets when moving sideways than straight ahead, challenging previous understanding of human spatial hearing. This discovery has implications for echolocation instructors and users, who can now turn their head away to improve accuracy.
Researchers analyze weekly markets in Catalonia to highlight the cultural significance of vendors' pitches and their role in promoting diversity and spontaneity. The study shows that such practices can be a form of intangible cultural heritage, attracting customers who value uniqueness.
Research found a link between genetic variants that mimic statin medication effects and increased risk of developing cataracts. Genetic analysis revealed carriers of rare mutations in the HMGCR gene have almost complete protein inhibition, similar to taking statins.
Researchers discovered that copper availability affects the release of nitrous oxide, a potent greenhouse gas. When copper is not available, microbes release more harmful gases instead of nitrogen, which makes up 78% of Earth's atmosphere. By adding metal to natural systems, it may mitigate nitrous oxide release.
Researchers found that user-initiated corrections with reliable sources consistently helped users reject fake news. Individuals with higher health anxiety and conservative political stance were more susceptible to misinformation. The study encourages social media users to correct fake news they see online if they have a reliable source.
A recent scientific review suggests that the oral microbiome may hold key answers to pancreatic cancer development, diagnosis, and treatment. The study found a distinct association between oral microbiome patterns and pancreatic tumors, with certain disease-driving bacteria identified in both.
Children are at higher risk of health changes due to air pollution and climate change impacts, including increased asthma rates and vector-borne diseases. Caregivers can take steps to minimize exposure by making personal and family changes such as using electric cars, reducing meat consumption, and improving indoor air quality.
A new study published in The Journal of Urology found that a super-pulsed thulium fiber laser system improved stone-free rates and reduced residual fragments in pediatric patients with urinary stones compared to standard low-power holmium:yttrium-aluminum-garnet lasers. The study, which evaluated 125 procedures in 109 patients, showed ...
A novel staging framework assesses Huntington's Disease progression and enables early-stage clinical trials of drugs. The HD-ISS groups patients by biological, clinical, and functional characteristics, allowing researchers to evaluate therapeutics in the earliest stages of disease.
Researchers identified a three-gene signature in multiple myeloma tumors that predicts a positive response to selinexor-based therapy. The discovery could improve patient selection for targeted agents and expand the use of the drug into patients who haven't failed other therapies.
A new species of large carnivore, Tartarocyon, has been discovered in the Pyrenees with a fossilized lower jaw weighing around 200 kg. The discovery provides insights into the development of European 'bear dogs' during the late Miocene period.