A novel form of chemoimmunotherapy has been proven to be a promising treatment for canine cancer, extending the lives of terminally ill dogs. The therapy uses modified Mesenchymal Stem Cells carrying a potent 'kill-switch' that induces anti-cancer immunity and improves quality of life.
Research from Cornell University finds that replacement work-from-home (working during regular hours) boosts psychological well-being and engagement, while extension work-from-home (working outside of regular hours) leads to lower well-being, higher turnover intentions, and conflict between work and family. Women are particularly affec...
The study found that the lack of capacity in wastewater treatment works is a fundamental cause behind increased frequency and duration of Combined Sewer Overflows (CSOs). This refutes suggestions that blame unpredictable weather for the issue. CSO use has been increasing, with most of it attributed to WWTWs' inadequate capacity.
Researchers at Complexity Science Hub developed a model using physics principles to predict group sizes in humans. By analyzing social stress and homophily, they found that group sizes can be predicted with relatively small information, revealing new insights into human behavior.
Researchers found that spinal cord stimulation improved insomnia severity index and Epworth sleepiness scale scores by at least 30% in 39.1% and 28.1% of participants, respectively. The study also established minimally clinical important difference values to gauge treatment success.
Researchers at Tampere University have developed a polymer-assembly robot that can fly by the power of wind and be controlled by light. The fairy-like robot has several biomimetic features, including high porosity and lightweight structure, allowing it to float in the air and travel long distances with stability.
A team of psychologists found that adopting a partner's perspective reduces the likelihood of infidelity and other partnership-destroying behaviors. By putting themselves in their partner's shoes, individuals can increase commitment and desire for their current partner, while decreasing interest in alternative mates.
Researchers found muskies' size, boldness, and exploration levels are linked to their likelihood of striking. Anglers should prioritize catch-and-release and best practices to protect these traits.
A new approach recovers the elastic tensors and moduli of superionic materials through first-principles molecular dynamics simulations. This resolves a significant overestimation issue with static methods, providing accurate reference results for three benchmark materials.
A study using tree rings reveals a 400-year trend of increasing droughts and floods in the Kabul River Basin, with severe events becoming more frequent. The research suggests that climate change is intensifying hydrological cycles, leading to devastating consequences for natural resources management.
A systematic review and meta-analysis of 34 studies found individuals with autism have a higher associated risk of developing diabetes, dyslipidemia, and heart disease. Clinicians should monitor individuals with autism for early signs of cardiometabolic disease and its complications.
Researchers from the University of Tsukuba found that mandatory cognitive testing during driver's license renewals in over-75-year-olds leads to decreased motor vehicle crashes. However, this policy change is associated with an increase in bike and pedestrian injuries among the same population.
A recent study published in the Journal of Dental Research compared ten pharmacological interventions for managing tooth extraction pain in adults. The study found that NSAIDs with or without acetaminophen result in better pain-related outcomes than opioids with or without acetaminophen.
Anu, a Purdue University startup, received a $970,993 NSF SBIR grant to further develop its innovative Rotary Aeroponic Cultivation Chamber. The technology aims to increase yields while reducing energy consumption and environmental impact through multispectral photomorphogenesis and deep-learning algorithms.
Researchers have visualized the structural dynamics of 2D perovskite materials under light-induced excitation, revealing a transient lattice reorganization towards a higher symmetric phase. The study demonstrates the potential to tune the interaction between perovskite lattices and light.
Researchers at Drexel University have developed a wearable textile supercapacitor patch that can charge in minutes and power programmable electronics for almost two hours using MXene material. The innovative design enables seamless integration of technology into fabric, paving the way for health care technology applications.
Researchers have identified a new class of potent antimalarial compounds that target the parasite's sexual phase, preventing it from infecting mosquitoes and subsequently humans. The compounds inhibit the parasitic protein Pfs16, forming the strongest bond with the drug.
A new research project aims to promote dual-language development for children with autism in bilingual families. The study will examine the type of bilingual environment and factors related to their ability to speak or understand both languages.
Heavy rainfall in Northwest India and North China in September 2021 was unexpectedly high, triggering dire consequences. The study found that warmer conditions over continental Eurasia led to an anomalous cyclone in India, transporting abundant water vapor into the region.
Dr. Nico Spiller to develop new analysis methods using machine learning to analyze complex brain data related to memory, decision making, and movement. The fellowship aims to provide insights into neurodegenerative diseases such as Alzheimer's and Parkinson's disease.
A study by Oregon State University researchers found that synchronized fishing with dolphins in Brazil increases the number of fish caught and supports both species' survival. The cooperative relationship is specific to this population of dolphins and has been passed down through generations of fishermen.
Researchers developed a neural network model that uses terahertz time-domain spectroscopy data to predict burn healing outcomes with high accuracy. The new approach improves upon existing methods by reducing training data requirements, making it more practical for processing large clinical trials.
Researchers applied deep learning techniques to a previously studied dataset of nearby stars, uncovering eight previously unidentified signals of interest. The new approach enabled faster and more accurate results, with the potential to accelerate discovery of extraterrestrial life.
Researchers at UCF have developed single-atom platinum catalysts that reduce the amount of precious metals needed in catalytic converters. These improvements can enhance catalytic performance while minimizing environmental harm.
Researchers have created a new type of polymer that can be triggered by light, enabling faster chemical reactions and more efficient energy use. The polymers, which respond to different wavelengths of light, show promise for use in various fields, including pharmaceuticals and future Mars habitats.
Researchers successfully treated a young man with recurrent non-gonococcal urethritis caused by Mycoplasma genitalium using chloramphenicol. The patient showed improvement after 14 days of treatment, despite initial failure with first and second-line antibiotics.
A team from UMass Amherst developed an all-fabric pressure sensor that works even under pressure, allowing for long-term data gathering on health indicators like bone density and depression. The sensor can be worn in comfortable clothing, providing fine-grained details for remote detection of disease or physiological issues.
The researchers aim to create a set of tools to help other chemists select and produce the right crystal structures for new drugs, potentially saving time and cost. By understanding how molecules crystallize, they hope to speed up the development process and lower costs.
A Korean joint research team has developed a new tissue adhesive that restores damaged corneas by filling them and exposing them to light, potentially treating cornea ulcers without surgical interventions. The new sealant integrates well with adjacent tissues and promotes scar-free corneal tissue reconstruction.
Scientists have identified horizontally transferred genes in insect genomes as valid targets for selectively killing green peach aphids and whiteflies. Silencing these genes using RNA interference reduces pest survival by up to 40%, with potential expansion to other insects through 'stacking' multiple targets.
A new poll by Michigan Medicine and U-M found that 13% of people aged 50-80 experience addiction to highly processed foods, with higher rates among women and those in poor physical or mental health. The survey used a standardized questionnaire to measure addictive eating habits.
A study found that people with coeliac disease have a 27% increased risk of cardiovascular disease compared to those without the condition. Despite this, they tend to have lower BMI and blood pressure, which are traditional cardiovascular risk factors.
A team of researchers identified a rare lead compound, lead(II) formate, in various areas of Rembrandt's The Night Watch using micro and macro X-ray analysis. This discovery provides clues about the artist's pictorial practices and the reactivity of lead driers in historical paintings.
New biodegradable plastics can be strengthened by adding a small amount of cream of tartar or citric acid, making them suitable for bags and food packaging. The new materials are stronger than conventional bioplastics and some petroleum-based products.
The researchers suggest acknowledging factors like race, gender, and class background to impact course material. They also provide lesson plans, online resources, and social media tools to help instructors develop diverse syllabi.
Researchers at Rice University have discovered a new way protein structures communicate with each other to regulate hormone activity. This finding could lead to improved therapies for breast cancer and other diseases.
A new study has uncovered a nearly complete specimen of the ancient 'marine crocodile', Turnersuchus hingleyae, from the Early Jurassic period in Dorset, UK. The find provides crucial insights into thalattosuchian evolution and origin, suggesting that these creatures likely emerged around 15 million years earlier than previously thought.
Researchers found a quantifiable amount of microbiome within soft tissue sarcoma tumors, linked to patient prognosis and immune system interaction. The study's findings suggest that the microbiome plays a role in attracting cancer-fighting cells, such as natural killer cells, which can improve immunotherapy effectiveness.
Researchers from the Institute of Atmospheric Physics have created a new climatological range-based automatic quality control system for ocean temperature profiles. The system, called CODC-QC, uses 14 distinct quality checks to identify outliers and aims to provide a quality-homogenous database.
Researchers at Bar-Ilan University have developed a new type of artificial neural network that outperforms traditional deep learning architectures. By using tree architecture with single routes to output units, they achieve better classification success rates, paving the way for efficient and biologically-inspired AI hardware.
Researchers at La Jolla Institute for Immunology have discovered the detailed mechanism of action of Inmazeb, a three-antibody cocktail designed to combat Ebola virus infection. The study reveals new information about how the drug interacts with the virus and its potential effectiveness against additional species of Ebolavirus.
A study by researchers in Brazil found that loss of muscle mass during COVID-19 hospitalization is associated with the development of persistent symptoms such as weakness, shortness of breath, and fatigue. The study also showed that patients who lost more muscle mass had higher healthcare costs six months after discharge.
A new solid film can perform visible-to-UV photon upconversion for weak incident light while remaining photostable in air. The material has an ultralow excitation threshold and a high quantum yield, making it suitable for various applications.
A recent study published in Nature Climate Change has discovered that hybridization between species can help vulnerable populations adapt to climate change. Hybrid populations have been found to contain more genetic diversity, making them less susceptible to extinction due to environmental changes.
Characteristics of a patient's neighborhood and hospital where they received treatment are both associated with risk of death after inpatient surgical procedures. Efforts should include improving hospital quality and addressing drivers of neighborhood deprivation to reduce postoperative mortality.
A new study predicts which invasive non-native species could pose a future threat to the UK's Overseas Territories, with Gibraltar and Saint Helena most at risk. The list includes species such as green mussels, little fire ants, and brown rats that could outcompete native species and alter unique ecosystems.
Researchers propose a new hypothesis for developing small diameter vascular grafts (SDVG) that heal in a reconstructive manner. They aim to emulate the structure and behavior of living arteries, incorporating a blood vessel network within the graft walls.
Researchers at Flinders University and Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit developed a new DNA tracking technique to identify counterfeit antimalarial medicines. The 'pharmabiome' method analyzes environmental DNA (eDNA) found in fake medicine packaging, revealing differences between genuine and substandard tablets.
Researchers provide a comprehensive catalog of medical knowledge graphs, their creation, and usage. Medical knowledge graphs have wide-ranging utility in the medical field, including disease diagnosis and drug development.
A research team from HKUMed identified chronic Type I Interferon signalling as a driver of CD8+ T cell exhaustion and therapy resistance. The study highlights the harmful effect of IFN-I on tumour-killing CD8+ T cells, providing new insights into immunotherapy improvement.
Researchers have developed a technique for confining light in air using Mie voids, a novel building block that can manipulate and control UV radiation. The discovery has significant implications for optical sensing, trapping, and reprogrammable structures, with potential applications in fields like quantum emitters and metamaterials.
A research team led by Professor Kwang-Hyun Cho at KAIST has developed a fundamental technology to revert metastatic lung cancer cells to a non-metastatic state. This breakthrough could lead to the elimination of drug resistance and metastatic potential in cancer cells, while increasing their responsiveness to chemotherapy.
The world's first international clinical guidelines have been created to prevent and treat heart complications in children undergoing cancer treatment. The guidelines cover cardiovascular disease assessment, screening, and follow-up for pediatric patients receiving various cancer treatments.
A research team developed an AI-powered method to automatically detect single cells in microscopic images, achieving a mean Average Precision (mAP) of 0.989. This technology reduces human labor and improves single-cell analysis, enabling the discovery of new treatment methods for diseases.
A team of researchers has successfully modeled the complex fluctuations in soft X-ray signals detected by satellites using numerical methods. They were able to capture how the signal varied with the orbital motion of the satellite and reproduce it up to a factor of two, an impressive feat in the field.
Scientists have successfully triggered chemical reactions in AgI using mechanical energy equivalent to 420,000 atmospheres. This approach allows for solvent-free synthesis and could lead to the discovery of new battery electrolytes. The research used computational modeling to predict the behavior of the material under extreme pressure.
Patients with myelofibrosis experience significant symptom improvements when treated with momelotinib, including reduced spleen size and decreased transfusion dependency. The Phase III MOMENTUM trial reports meaningful benefits over standard therapy danazol.
A study published in Nature Astronomy suggests that a volcano-like rupture on the surface of a neutron star could have caused its sudden slowdown. The research used X-ray data from orbiting telescopes to analyze the magnetar's rotation and found evidence supporting this theory.
A study by the American Society of Anesthesiologists found that inaccurately recording anesthesia start times results in lost billing time for anesthesia practices and medical centers. The study analyzed 40,312 procedures and determined a potential loss of $638,671.57 in one year.
A new study suggests that Thai confectioners can gain a competitive advantage by using their country's local heritage and culture. The research found that youngsters in Thailand still enjoy local confectionary as well as Western brands, but local products have strong emotional value to them.